Please note that at 9:00 I made a small typo error when writing out metabolites of Gemcitabine. Gemcitabine diphosphate is abbreviated dFdCDP (not FdFCDP) and Gemcitabine triphosphate is abbreviated dFdCTP (not FdFCTP).
The way you explained the DeNovo synthesis at the start, to later relay a better understanding of how each drug works, was simply amazing. Sincerely, a pharmaceutical student looking to pass an equivalency board exam. Thank you very much, forever grateful :)