This is quite fascinating. Dr. Yong, do you find polynucleotides more effective than dermal fillers with poly-l-lactic acid such as sculptura? I’m curious what your thoughts are and what you’ve experienced in your patient population. IMO I think skin boosters like HA often make people look puffy and pillowy, which actually makes them look older and not a desirable look. However, I have seen higher molecular weight HA (profhilo) utilised on women’s underarms with crepey skin to completely eradicate the crepey skin to make it look firm and toned. I’m curious about which procedures you have done on yourself (if any) and where you tend to inject polynucleotides on your patients? I do know that in South Korea, rejuran (salmon sperm- a type of polynucleotide) is injected during micro needling sessions. However, I do not think I personally want salmon sperm injected into my skin. BTW I love how you explain everything quite thoroughly and try to educate your patients, I always think that is the sign of an excellent doctor. 😊
Thank you for your comment, @PtolemyXVII! The choice of injectables varies based on individual skin conditions and goals. Polynucleotides (like Rejuran) improve skin texture, while bio-stimulators (like Sculptra or Radiesse) focus on collagen production and volume loss. Profhilo is useful for areas with crepey skin but doesn’t address skin laxity as effectively. Hyaluronic acid boosters, when applied correctly, can enhance hydration without looking overfilled. It's always best to consult a skilled practitioner for personalised advice. Hope this helps!
Hello @ngoctrangle-alfonso9771, in general for skincare, antioxidants are good for most/all skin types, hyaluronic acid in a serum or moisturiser, niacinamide or other soothing calming agents like heartleaf can all be useful. It is recommended to incorporate a good antioxidant serum including a good potency vitamin C, broad spectrum sunscreen with at least Spf 40-50 and PA +++ in the day, and depending on skin type, using a retinol or retinoid 2-3 times a week can be helpful to preventing fine lines and photo-ageing. For injectables, some good products that improve skin quality, consider skin boosters that contain hyaluronic acid to hydrate the skin, polynucleotides to repair the skin and improve fine lines/pores, and also certain bio-remodelling injectables can be helpful to improve elasticity and hydration safely. At the end of the day, skincare and treatments are not a one size fits all and will vary depending on your skin's condition and your history. Do make sure to seek a professional's help for customised skincare to your skin type and condition if you have trouble addressing it yourself!
