you might just save me from failing my biochem test on transcription and translation. There's no time left to read books so i resorted to listening your lectures, the decision i'll never regret. You have given me hope. Thank you! Keep up the good work!
Transcription in AP Bio, transcription in microbiology, transcription in genetics, transcription in molecular biology, transcription in biochemistry, UGH!!!!!!!!!!!!!!
I really enjoy the videos, especially the fact that everything isn't shoved into one video but a series of videos. I'm only in gen. bio. 1 but this is very helpful.
I have a question. on the last part of splicing the exons, you mention about the poly(A) tail also spliced in the nucleus. And it is also mentioned before that, poly(A) tail aids in the transport of mRNA across the nuclear membrane. So, my question is why the poly (A) tail is spliced if it actually aids in the transport? or is it because its long structure is degraded gradually during the travel? Thanks in advance.
hi du have any vedes on chemistory from beginning because am rubish with molecules and bonding stuff, i wanna start from the begging of understanding atoms, thanks
HY! I have a question.u said splicing occur after adding caps and tail.but i said splicing before occur then add cap and tail.basically cap meaning protect if splicing after capping occur then cap not protect mRna?am i right or not?plz answer my question.thanks
One little nit-pick, on the diagram of the pre-mRNA, the introns look relatively small compared to the exons. In reality, introns tend to be far longer than exons (I say "tend" because their size varies). Again, just a nit-pick that I think is worth mentioning.
Thanks Good lecture, good explaining. Just please make writing bigger and don't put so much on the screen at once. It makes it very hard to read even on a full screen setting.
You're welcome! Not sure if there is a specific name for that complex but its basically a collection of different proteins and factors that work together to add the poly A tail and cap.
The methyl transferase is the enzyme which adds the methyl group basically the cap on the 5 prime end. The polyadenylation occurs through binding of cleavage stimulatory factors which recruit cleavage factors which cleave the mRNA. The poladenylations then begins with the addition of adenine residues by poly A polymerase (PAP).
I could be wrong , but i think you've made a mistake here. The exons are actually the coding regions for proteins! Introns are in fact the non coding regions!
