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Prion disease animation 

Nanobot Group
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Nanobotmodels animation studio presents medical and molecular biology education video about prion disease.
This video opens branch of education materials on molecular biology and medicine.
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19 сен 2024

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Комментарии : 243   
@CoasterCountry.
@CoasterCountry. 9 месяцев назад
Prions are one of my worst fears. They're infectious, they're uncureable, and they always result in death. Also they're INCREDIBLY painful. And the worst thing is, it's so hard to develop a cure because they aren't even alive.
@user-op8fg3ny3j
@user-op8fg3ny3j 6 месяцев назад
It's like a radioactive virus
@exosproudmamabear558
@exosproudmamabear558 Месяц назад
But they are proteins which proteases can degrage and bind unfortumately we are still cave men who doesnt understand how proteines and enzyme works
@tinang5999
@tinang5999 6 лет назад
My brother died last night at 1:00 after 6 weeks. They call CJD. I am still shaking and also confusing. So painful and horrible 😢. I love my brother so much.
@michaelpanichella707
@michaelpanichella707 6 лет назад
Ewww, Sorry to hear that. :(
@laffydaffy5133
@laffydaffy5133 5 лет назад
Hello. After a year are you coping with it better. I know how hard losing a loved one is. We all have to go through this at some point in our lives. Hope you're doing better.
@VividlyNight
@VividlyNight 4 года назад
Tina NG I feel sorry for you. May your brother rest in peace
@Ivan_1791
@Ivan_1791 4 года назад
How did it happen? Did he eat contaminated meat?
@Stevder
@Stevder 4 года назад
This is so sad to heard that...its terible 😭
@computerfraudandabuseactof43
@computerfraudandabuseactof43 4 года назад
Who would wi: The human brain, the most mysterious and complicated structure in the universe, or some weird proteins
@niklasvilhelm7247
@niklasvilhelm7247 4 года назад
This is not really the best place for jokes
@insanejarviimeanredspot7491
@insanejarviimeanredspot7491 3 года назад
@PSYKING 666bad take
@baseballworldwide9439
@baseballworldwide9439 2 года назад
@@insanejarviimeanredspot7491 just saying "bad take" is not an argument
@inesab.5901
@inesab.5901 Год назад
@@baseballworldwide9439 It wasn't really true though
@thefumyandthechev
@thefumyandthechev 8 месяцев назад
​@@niklasvilhelm7247"oh no someone died' dude, every second around 2 people die
@EEGMan
@EEGMan 10 лет назад
its excellent. Is there supposed to be a sound track (not that its needed)
@ebsss100
@ebsss100 4 года назад
I wish there was one
@Queen.Sindel
@Queen.Sindel 4 года назад
Is it me or the vid really has no audio?
@Trianglewitch.
@Trianglewitch. 7 лет назад
So it reproduces by conversion and not replication like every thing else. Freaky!
@RoyalBlueJay
@RoyalBlueJay 3 года назад
Yep, pretty much a zombie protein. Infects other proteins and doesn't die.
@СветланаТрофимова-у2щ
The shittiest disease
@dimdimbramantyo7666
@dimdimbramantyo7666 3 года назад
And the mortality rate is 100%, really scary
@Monkeytype6
@Monkeytype6 3 года назад
Saw an article proposing that prions can also be in the form of Rna...
@spaceedementia
@spaceedementia 3 года назад
That has some dark implications
@juliekonicke5329
@juliekonicke5329 2 года назад
Mrna
@luftwaffle3766
@luftwaffle3766 2 года назад
U know central dogma?
@luftwaffle3766
@luftwaffle3766 2 года назад
If it folds it can turn to prion
@jjk2one
@jjk2one 7 месяцев назад
@@luftwaffle3766 pacman a ----m ///?? o +++ E} B A
@Juleka-and-roaar
@Juleka-and-roaar 11 месяцев назад
fact: prions can slao be in fungi! its much more common to have prions in fungi then in animals.
@mexicanchamp2282
@mexicanchamp2282 4 года назад
How can something so evil and fucked up exists? Omg
@MH-up1xe
@MH-up1xe 3 года назад
It’s almost like a cheat code to kill humans. Make me wonder if something out there is trying to stop biological beings.
@competitiveshooter9577
@competitiveshooter9577 11 месяцев назад
Natural Population control agent maybe?
@KRAKEN91O
@KRAKEN91O 3 года назад
Just a few modifications and I think we can make Zombies work
@bigiecheese919
@bigiecheese919 3 года назад
Rna will work
@juliekonicke5329
@juliekonicke5329 2 года назад
Mrna
@xXanonxxefgXx
@xXanonxxefgXx 4 года назад
What does the text say from 3:30 through the end of the video regarding Kuru? Some preview thumbnails pop up blocking the information.
@B0rgerX_
@B0rgerX_ 3 года назад
Although it's considered a transmissible prion disease via cannibalism among members of the Fore tribe or Papua New Guinea
@jjk2one
@jjk2one 7 месяцев назад
@@B0rgerX_ That area had more gold than anywhere in the world, figure it out.
@ourochroma
@ourochroma 4 года назад
SO you're telling me, that the decease's strands cling to the neurons like a parasitic coiling plant? So Metal...
@4L3PH4
@4L3PH4 8 лет назад
Amyloid plaques themselves aren't neurotoxic. For example, PrP knockout mice don't suffer neurodegeneration when inoculated with PrPSc.
7 лет назад
4L3PH4 wrong
@4L3PH4
@4L3PH4 7 лет назад
So explain the phenomenon I mentioned. There's a Nobel prize waiting for you. Ok , you're just a troll.
@jamaursa
@jamaursa 7 лет назад
PrP knockout mice don´t suffer neurodegeneration when inoculated with PrPSc, because the host susceptibility to scrapie infection and prion propagation requires the expression of PrP. But doesn´t explain if amyloid plaques are neurotoxic or not.
@jessd956
@jessd956 7 лет назад
Veronica Baragona wait, could you please explain what turns into spirochetes and how? I'm interested because I have Lyme disease which is linked to dementia, and Alzheimer's where 100% of plaques in certain brains contained spirochetes, and also, nematodes containing spirochetes have been found in Alzheimer's brains.
@kumarvishokanand3992
@kumarvishokanand3992 4 года назад
@@jessd956 hey are you OK?
@antonio8693
@antonio8693 4 года назад
This thing gave me nightmares
@jamesJohnson-qe4gw
@jamesJohnson-qe4gw 3 года назад
What is the difference between prions and "spike proteins"
@spurdosparde9487
@spurdosparde9487 3 года назад
Different acids and structure
@blockerhall4532
@blockerhall4532 Год назад
Spike proteins are on viruses, the thing is prion proteins aren’t viruses or bacteria, they sit on the surfaces of the nerve cells in clusters of thousands and if one goes wrong they replicate by a domino effect that spreads across the brain, or from the gut to the brain.
@Rudol_Zeppili
@Rudol_Zeppili 8 месяцев назад
If spike proteins were prions literally everyone who has ever gotten a virus with spike proteins would be dead. That isn’t the case at all, we can resist viruses and get better from the illness caused by them most of the time, while with prions not so much.
@jjk2one
@jjk2one 7 месяцев назад
@@blockerhall4532 isn't allowed here what it really is, it's very simple and diabolic.
@blockerhall4532
@blockerhall4532 7 месяцев назад
I’m confused please elaborate
@VZerda
@VZerda 10 лет назад
You're confusing me by calling PrPc a prion rather than a (normal) protein. They're most definitely not the same thing. This mistranslation could be very confusing for us English speakers, I hade to cross-reference to make sure I wasn't crazy.
@Th-Rbt
@Th-Rbt 2 года назад
A prion is a normal protein, though when referred it can be abnormal protein but in reality thats called a diseased Prion, some call it a prion and the rest protein instead of prion disease like it should, prions help with stress and other causes, they have proteins that are normal, while prions disease or abnormal prion/protein or folds in a protein that is not normal and that could infect others, and because it does harm, its called a prion disease
@Th-Rbt
@Th-Rbt 2 года назад
I forgot to include that a prion is also short for prion protein, and which is hard to understand it’s uses rather than stress relievers, so when the guy says prion he means prion protein which could be useless yet when transforming into a prions disease is fatal
@Th-Rbt
@Th-Rbt 2 года назад
Yeah language is being mixed up here which is why we need to more videos to clarify different meanings, see even the Oxford dictionary was wrong on the definition of prions since it’s so complex and one can spend hours researching this topic
@matijasedmak8056
@matijasedmak8056 2 года назад
@@Th-Rbt one question, what is that stringy curly green thingy inside the protein? Is the the prion?
@draliasadullah
@draliasadullah 4 года назад
Thank you for such a great animation!
@rezarohani4088
@rezarohani4088 3 года назад
How come this clip has no sound and is mute?!
@amberblyledge7859
@amberblyledge7859 6 лет назад
And here I am wondering why the animation has to be so twitchy.
@lizexi7115
@lizexi7115 3 года назад
Am very late at the party but basically in molecular levels, theres a lot of vibrations due to heat. Heat is basically molecules moving and vibrating.
@masonisgaming5225
@masonisgaming5225 3 года назад
We're both late to the party. But why? Ask yourself, "why am i watching this?" And then you'll know something about the future. . Deer all over the world are contaminated. . It's only a matter of time. .
@amberblyledge7859
@amberblyledge7859 3 года назад
@@masonisgaming5225 I didn’t know it had gone global. I’ll have to double check that. CWD is the kind of thing that happens when we screw with the natural predators that keep this in check. Yellowstone is a prime example.
@lizexi7115
@lizexi7115 3 года назад
@@masonisgaming5225 Prions only affect CNS, one dies but other are still alive. Prions are also broken down in digestive system most of time. Its only when body fluid come in contact: rubbing eyes and cannibalism that the disease is transferred. No worry
@ReptillianHumanoids
@ReptillianHumanoids 3 года назад
@@masonisgaming5225 this is what the covid vaccines are doing to people
@rosariovarela2882
@rosariovarela2882 9 лет назад
No audio?
@zaiman97
@zaiman97 8 лет назад
Intelligent people don't need audio nor music.
@julesverne6287
@julesverne6287 8 лет назад
+Zaiman Syahzmi some of us like it though
@sandeepsonawane3535
@sandeepsonawane3535 6 лет назад
Rosario Varela
@savvyyahv8272
@savvyyahv8272 4 года назад
@@zaiman97 the issue is not Intelligence, it's trying to quickly read the words on the video without missing the transformation of the prions in question....🤔
@AJArmin
@AJArmin 20 дней назад
Very difficult to understand about these prions, so I understand they still have no cure.
@jacobbosley2144
@jacobbosley2144 4 года назад
"...It also results in very large electrostatic forces of attraction between the nucleus and the valence electrons in the 2s and 2p shells, resulting in very high electronegativities. Hypervalency is almost unknown in the 2p elements for the same reason, because the high electronegativity makes it difficult for a small nitrogen atom to be a central atom in an electron-rich three-center four-electron bond since it would tend to attract the electrons strongly to itself." is it possible this fundamental mechanic of nitrogen is what causes the proteins to fold?
@jjk2one
@jjk2one 7 месяцев назад
it's "pacman" controled by polarity and "swarming" behavior. (batteries)
@sebaxxxish
@sebaxxxish 4 месяца назад
Which book are you citing my friend? I'dike to read the whole chapter
@jaidagr8
@jaidagr8 9 лет назад
Just Beautiful....
@parisreilley6743
@parisreilley6743 11 месяцев назад
Would feel better if there wasn't misspellings in the text, unless 'incide' is a new spelling.....
@taniyakruplani8150
@taniyakruplani8150 11 месяцев назад
the best.
@lakshitha3851
@lakshitha3851 3 года назад
Vera level animation 🔥
@klavesin
@klavesin 10 лет назад
Спасибо огромное за видео, очень познавательно! Возможно, будут полезны небольшие поправки в английском: 0:44 are crossing -> лучше are penetrating 1:05 membrana -> membrane 1:13 happen incide -> happens inside
@shellbacksclub
@shellbacksclub 7 месяцев назад
My uncle was diagnosed with this just before the new year, today he can no longer swallow... Please find a cure! This is the worst!
@SlavTiger
@SlavTiger 3 месяца назад
It's nigh impossible to stop once it starts, researchers are still unsure why exactly it happens in the first place and once it starts, it's a domino effect
@brienluck4783
@brienluck4783 Год назад
Good animations, but needs sound.
@PhillipYewTree
@PhillipYewTree Месяц назад
White text on pale blue is not easy to read.
@김소연-f2m6m
@김소연-f2m6m 5 лет назад
감사합니다!! 잘 보고 가요~
@প্ৰাণপ্ৰতিম
No sound??
@zed1671
@zed1671 8 лет назад
Nice video, thanks
@meghanmaxwell2993
@meghanmaxwell2993 9 лет назад
What organelle produces normal prion protein? smooth or rough ER?
@DaveMH1985
@DaveMH1985 9 лет назад
Meghan Maxwell PrPC is synthesized in the rough endoplasmic reticulum and transits through the Golgi apparatus on its way to the cell surface
@cabdarasaqcomar9882
@cabdarasaqcomar9882 7 лет назад
Meghan Maxwell it produced by ER as well as come from.ou of body
@medicalalex7610
@medicalalex7610 2 года назад
really thanks.
@Cece-cp1in
@Cece-cp1in 11 месяцев назад
There's no sound
@michaelmiller8205
@michaelmiller8205 9 месяцев назад
No Sound ??????
@abacaxirusso2023
@abacaxirusso2023 6 месяцев назад
Caraca mano boa animação
@DanhNguyen-wg5lu
@DanhNguyen-wg5lu 4 года назад
Wonder why suddenly all u guys practice social distance hmmm..hmm
@baseballworldwide9439
@baseballworldwide9439 3 года назад
Lmfao just stop. Surprised you had the intelligence to spell “Prion”
@whosyourdaddy4579
@whosyourdaddy4579 3 года назад
No sound!
@iliayasny
@iliayasny 10 лет назад
Спасибо! Почему-то в этом видео нет звука, в отличие от остальных
@TANSZ548
@TANSZ548 11 месяцев назад
fatal sporadic insomnia
@deepthibalaji4519
@deepthibalaji4519 8 лет назад
A brilliant video :)
@blockerhall4532
@blockerhall4532 Год назад
I’m so sure I’ve got variant cjd I’ve had these symptoms since September 2020 muscle twitches and visual disturbances and sleeping problems, now there’s a blind spot appearing in my left eye and some weakness in my right leg, and two weeks before all this I was woken with a punch in the gut sensation, and vcjd spreads from the gut.
@nenduu
@nenduu Год назад
:(
@art1k243
@art1k243 Год назад
how are you?
@blockerhall4532
@blockerhall4532 Год назад
I’ve got the same symptoms, and there’s a blind patch slowly getting Worser in my left eye.
@art1k243
@art1k243 Год назад
@@blockerhall4532 so what is your diagnosis? Have you been tested?
@blockerhall4532
@blockerhall4532 Год назад
The doctors haven’t diagnosed me yet, but I’ve had an mri scan that was normal.
@TovenDo.O.Video-
@TovenDo.O.Video- 2 года назад
So it's just a r-et-4rd3d protein
@oahuhawaii2141
@oahuhawaii2141 Год назад
01:20 "incide" -> "inside"
@ellios5734
@ellios5734 2 года назад
For hot second I thought I'm deaf
@Pastel522
@Pastel522 3 года назад
Why this on my recommended
@biohazardaxx1332
@biohazardaxx1332 7 лет назад
prion plague inc.
@lanchanoinguyen2914
@lanchanoinguyen2914 7 лет назад
that's must be called the cancer type.
@yuvarudra6602
@yuvarudra6602 2 года назад
By some how i get the funny feelin that am deaf since i cant hear anythin. 😨🤯
@rakhichakraborty5164
@rakhichakraborty5164 3 года назад
i dont understand how the prions are harmful
@juliekonicke5329
@juliekonicke5329 2 года назад
Prions are in our Brains. Humans are not to eat themselves especially their own brains. Neither are Cows or any other animal. When you see two lions fight to the death the one that wins does not eat the other one! Not natural
@anandisrocking007
@anandisrocking007 7 месяцев назад
Anyone came here after reading the nature of predator novel......😅😅😅😅
@omkr0122
@omkr0122 4 года назад
This is the reason why Jurrasic Park failed! DX Disease...
@JDMKEV
@JDMKEV Месяц назад
"INCIDE"
@toichoiroblox24
@toichoiroblox24 3 года назад
Real zombie virus
@competitiveshooter9577
@competitiveshooter9577 11 месяцев назад
Prion is NOT a virus
@ColemanBentz-m8z
@ColemanBentz-m8z 3 дня назад
This video is so 2024
@izzi1931
@izzi1931 3 года назад
Trains fucking podcast...
@rrpo811
@rrpo811 9 лет назад
many sheep on this RU-vid channel. This is only a cartoon based on theory and anybody who knows anything about science is that theory is always replaced with another theory. This means that theory is not based on fact so to take this as fact is laughable.
@rrpo811
@rrpo811 9 лет назад
+Le “DaggerWrath” Dagz evolution has not been proven. and never will be
@antonk.2748
@antonk.2748 8 лет назад
+rr po So then, my stupid friend, pls step outside and go for a flight, because gravity is also a theory. Furthermore, please allow me to ask what you are studying, or what is your area of expertise to write such (fairly amusing) rubbish? I am 4th semester microbiology student, I can tell you that there are prions and evolution does happen and was proven a long time ago, just because you and your tin foil hat wearing friends of religious morons dont accept any sort of scientific prove doesnt mean it is not proven. Accumulation of mutations leading to a different species happens literally every couple years in viruses. The reverse-transcriptase of some viruses and the DNA/RNA polymerase of most viruses are of such low grade that mutations are very very common (sometimes 1 point mutation every transcription), which is actually advantageous to the virus, because it creates more variety. Funny enough you talk about sheep, because A) you are one and B) Prions actually cause a disease in sheep called scrapie, and there you go, existence of prions proven, because in the brains of these sheep scientists ( these are the guys that actually know what they are talking about, unlike shitheads like you) found prion proteins. So, pls believe in your own stupidity, and hopefully die sometimes from rather praying to "god" then visiting a doctor, but please dont spam the internet with retarded comments like the one above.
@rrpo811
@rrpo811 8 лет назад
+Anton Kubala Uh ho an academic watch out. So you say your degree is in micro biology, that degree is a BS not a BA which is a supreme to me because you can take most of that curriculum on line. Me, personally ally would have never wasted 100,000 on a degree like that. Though you could have had many grants because your race, but that is another problem in this countru. So for now we will concentrate on the Big Pharma agenda that you so happy and gullible accepted. You start off with ignorance I might add, appealing to gravity as your defense for your argument on theories. We'll since I am wasting my time responding to a statement that is just a bunch of regergitated tripe you took from your joke that you call a degree I will happily set you straight on gravity. Gravity is an actual event though theory of gravity, which you should know is how and why it occurs can change as the science on gravity matures. So please when you use a fact to argue a point get your facts straight. Now that I know I am dealing with a child who has just achieved to obtain more ignorance from a field that is riddled with an agenda driven base, I can keep this simple. You start your argument with prions and you try to prove your point with viruses. We'll earth to the academic they are two totally different things. Since you are an academic in the field of micro biology I thought you would realize this but you don,t. A bit of advice for the young acedemic, intelligence is not measured by the knowledge one obtains but the common sense that one uses to analyze and use the information that was achieve. Yes, I do have a higher degree in science,true science and is much more respected than the degree you are trying to achieve.
@antonk.2748
@antonk.2748 8 лет назад
Lol, are u seriously arguing a Bachelor of Arts is more scientific then a Bachelor of Science? U gotta be kidding. What I do is real science, I stand in the lab for hours, do research, what you do, I dont know, but it is not scientific. I dont do my degree in the USA (luckily) but in the UK, I dont get any grants or anything ( how the fuck are you linking that to a race issue????) I didnt even mention anything about pharma, ( but I know, you pseudo-scientific conspiracy theorists love to just go from one topic to another). I know that prions and viruses are entirely different (because I am actually studying it for quit a while now), even thou some aspects are comparable. I used viruses as an example of every day evolution. What exactly is your higher degree in "true science"?? If its not a Biological or Chemistry degree, please spare me any further "arguments", because you are surely not qualified nor have the knowledge to give any, which is clearly shown by your first statement.
@rrpo811
@rrpo811 8 лет назад
Apparently, you don't understand what you are reading. I am saying your degree might as well be a liberal arts degree you moron.
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