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Propensity scores: Everything you need to know in 5min 

Michael Fralick
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This is a crash course on propensity score methods. If you don't know what a confounder is, watch this first: • Why double-blind rando... . If you don't know what regression is can skip to 38min mark and watch this: • An introduction to cli...
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12 ноя 2021

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Комментарии : 71   
@JacobRasey
@JacobRasey Год назад
Been reading articles about propensity scoring in multiple different articles but this is by far the most reasonable and down to earth description
@Fralickmike
@Fralickmike Год назад
thank you very much!
@user-yw1ul4xq1g
@user-yw1ul4xq1g Год назад
Wah, many thanks, Sir. This 5 mins is probably more useful than a paid stats course🙏👍😊
@ghadah9120
@ghadah9120 3 месяца назад
Michael, the man that you’re!! Thank you from the bottom of my heart.
@HsimingLiu
@HsimingLiu 2 года назад
Very informative and concise introduction! Thank you very much!
@wisdomindABC
@wisdomindABC Год назад
Excellently lucid explanation!! Great job ✅
@lingfeitang8213
@lingfeitang8213 2 года назад
Very nice video. Covered the big picture information on why we do it and how we do it in a very concise format. Would be great to get the details on how to Performa matching in a stats package (is it a manual process or can be automated). That would probably make it much longer than 5 mins, but I believe it would be very useful). Another thing: I wanted to watch with subtitle but somehow the closed caption is Vietnamese. Thank you for the video!
@yulia6354
@yulia6354 Год назад
wow! Thank you for such a concise and clear explanation! It was pure pleasure to watch!
@Fralickmike
@Fralickmike Год назад
thank you!!
@FROSTHAWK247
@FROSTHAWK247 3 месяца назад
I am a masters student studying social work and even when the focus of the research is different the process of calculating these scores is more or less similar. This video was a great deal of help and extremely digestible, thank you so much!
@Fralickmike
@Fralickmike 3 месяца назад
That’s very kind of you. And I’m glad you found it helpful !
@nattachainew6330
@nattachainew6330 2 года назад
Excellent presentation ! very informative and concise. thanks for sharing
@Fralickmike
@Fralickmike 2 года назад
Thank you!
@Calvindi
@Calvindi Год назад
Excellent, clear and concise interpretation!
@Fralickmike
@Fralickmike Год назад
Thank you!!
@yuyangzhu6822
@yuyangzhu6822 10 месяцев назад
Thank you for the video!! saved me when I got totally lost in my intermediate pharmacoepidemiology class 😂
@danielaperezvasquez3340
@danielaperezvasquez3340 2 месяца назад
Omg!! This was perfect thanks!
@akshitbhalla874
@akshitbhalla874 5 месяцев назад
Thank you so much for making this video!
@Fralickmike
@Fralickmike 5 месяцев назад
My pleasure. Thank you for your kind words!!
@jananys3156
@jananys3156 2 месяца назад
thank you so much for this video helped me with my journal club!
@user-dominhtung
@user-dominhtung Год назад
Many Thanks sir. Your explanation is clear and easy to understand.
@Fralickmike
@Fralickmike Год назад
You are most welcome
@josefoso15
@josefoso15 4 месяца назад
Fantastic! Nicest explanation of PSM ever
@Fralickmike
@Fralickmike 4 месяца назад
Thx so much!
@user-uu7co5li9v
@user-uu7co5li9v 6 месяцев назад
Thanks for the clear explanation!
@Fralickmike
@Fralickmike 6 месяцев назад
My pleasure. Thank you for watching
@datadoctor10
@datadoctor10 10 месяцев назад
Thanks for the video
@jekamito
@jekamito Год назад
Nice job. Thank you. 😊
@Fralickmike
@Fralickmike Год назад
You are most welcome
@ericyeh4315
@ericyeh4315 7 месяцев назад
genius! deeply appreciate this video! helpful for med students drowned by statistical terms
@Fralickmike
@Fralickmike 7 месяцев назад
Thank you !
@sucharitaray5488
@sucharitaray5488 2 года назад
Sir we need more and more videos like this. Survival analysis, what test to use in what situation etc.
@Fralickmike
@Fralickmike 2 года назад
Thank you! i agree and hope to add more soon
@yutingchen9701
@yutingchen9701 7 месяцев назад
great video!
@Fralickmike
@Fralickmike 7 месяцев назад
Thank you!!
@Chrissi961
@Chrissi961 Год назад
thank you, I finally got it (2 days before my exam) :)
@Fralickmike
@Fralickmike Год назад
Great to hear!
@ec.juanfranulcuangolee3294
@ec.juanfranulcuangolee3294 Год назад
Thank you dear teacher. Excellent, in spite of it wasn't in Spanish or without subtitles
@Fralickmike
@Fralickmike Год назад
You are welcome!
@alsonyang230
@alsonyang230 Год назад
Thank for the concise videos that explain the overall concept very well. It was very easy to understand. There are 3 implementation details during the matching phase (at 5:00) hoping you could clarify. 1. After we get the score, if there are two rows with scores 0.5 in control group (where `SGLT2 = No`), should both of them be matched to row 3 in treatment group? 2. In the real world, the score would rarely be exactly the same if we allow infinite decimal. How do you consider a match? Would there be an arbitrary numeric difference allowed? 3. If there are two rows in treatment with score 9.15 and 9.18 (row A and B), and two rows in control with score 9.16 and 9.25 (row C and D). Would row A and B both be matched to C? Or would row A matched to C as they are have the smallest difference, then row B has to be matched to D?
@Fralickmike
@Fralickmike Год назад
The stats section of this article will help answer your Qs www.acpjournals.org/doi/10.7326/M19-2610
@joelkitha7802
@joelkitha7802 Год назад
thank you for this
@Fralickmike
@Fralickmike Год назад
You are most welcome
@frankvanschellen4980
@frankvanschellen4980 4 месяца назад
thank you for this great explanation! Is there also a possibility when having 3 treatment groups to calculate propensity scores with the same strategy?
@Fralickmike
@Fralickmike 4 месяца назад
You’re most welcome. There is but that gets complicated fast! If there are 3 groups and one is the ref then I do two pair wise comparisons to the ref. Hope that helps.
@silverlight7938
@silverlight7938 6 месяцев назад
Really helpful, I wanted to ask What is the difference between Propensity score matching and Case control matching (SPSS)?
@Fralickmike
@Fralickmike 6 месяцев назад
Case control matching is unrelated. Here is great resource on everything you need to know about case control studies sphweb.bumc.bu.edu/otlt/MPH-Modules/EP/EP713_Case-Control/
@chadibenchakroun6465
@chadibenchakroun6465 Год назад
Can you please explain the slide at 5:10? Why don't we have the same number of persons, means...? Is it just that we do not take into account people without a match?
@3alanii
@3alanii Год назад
thanks, great video. what are the pros and cons of weighting vs matching?
@Fralickmike
@Fralickmike Год назад
Pro - you retain all participants (or almost all) Con - harder to explain to readers, you create a “synthetic” population (which is also hard to understand!) The risk of bias is similar with matching vs weighting. So I stick with matching
@3alanii
@3alanii Год назад
@@Fralickmike thanks. one other question please, how come some do both propensity score matching/weighting and then Cox adjustments for variables? if the population is similar after propensity score matching then what does the cox adjustments add?
@A_Psych_Nurse
@A_Psych_Nurse 7 месяцев назад
Hi Michael, Appreciate this breakdown, despite most of it going over my head. When you say these statistical methods do not mimic RCTs, what exactly does that mean? How closely do we get to the results of a RCT using this method, and has this method been verified against the findings of RCTs? The reason I'm asking this is b/c I came across a cohort article comparing adolescents who took antipsychotic medication vs. those who didn't, and compared how they were doing 5 years later. The article suggests, after using IPTW, that antipsychotic medication in those w/ their first episode of psychosis, actually makes for a worse 5 year outcome. I'm skeptical though b/c it's a cohort study and no randomization was done. The authors acknowledge this weakness, and then state that the Stabilized IPTW is used to eliminate the possibility that those with worse psychosis were the ones who were given an antipsychotic medication. (I think this is the most probable explanation for why those who were given AP medication fared worse. . .simply b/c they already were experiencing more profound psychosis and so we would expect them to be doing worse at a 5 year follow-up). Seems super fishy to me. . .any thoughts here are appreciated, thx.
@Fralickmike
@Fralickmike 7 месяцев назад
You are totally right to be skeptical. There’s no way to answer this Q “how close do we get to the results of a RCT”. It would be like asking how much does this glass of wine taste like a beer. They are two different things. To learn more about why RCTs are so powerful and what randomization achieves (that no cohort study can) here is link to my 6min crash course on RCTs: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-oQt8jR5RgVQ.htmlsi=cpMn3c6YQnWYj3wv
@A_Psych_Nurse
@A_Psych_Nurse 7 месяцев назад
awesome, thank you for the insanely prompt and helpful response Michael!@@Fralickmike
@-shaw360
@-shaw360 Год назад
Can you use mediators in addition to / in place of confounders as your variables when calculating propensity score?
@Fralickmike
@Fralickmike Год назад
Good question. I have never done this before and would probably suggest against it.
@gopalakrishnanms
@gopalakrishnanms Год назад
Can one use the propensity score as the probability of death in 14 days (say, using an online calculator like CRASH for traumatic brain injury) and then match patients with similar probabilities of death to see if a particular treatment has lower mortality than another one? If the treatment had an effect, there would be a difference in the actual mortality rates? Is that a valid propensity matched analysis? How does one find the sample size for such an analysis?
@Fralickmike
@Fralickmike Год назад
No. Propensity scores are not used to match on outcomes. That’s a disease risk score
@saminaaftab3088
@saminaaftab3088 2 года назад
kindly guide how to analysis step by step in.spss
@Fralickmike
@Fralickmike Год назад
avoid SPSS. use R, it is way easier for propensity score methods like the matchit package
@jayagupta9239
@jayagupta9239 Год назад
how do we get weights as 0.6 and 0.9 ? can you please elaborate
@Fralickmike
@Fralickmike Год назад
what do you mean?
@NickGhale
@NickGhale Год назад
You run the regression in your software using the age and sex as inouts
@girlthatcooks4079
@girlthatcooks4079 9 месяцев назад
There are 3 scores as 0.6, would it be fair/unbiased to match with random 2 only?
@Fralickmike
@Fralickmike 9 месяцев назад
that is a good question. you are right that it would be ok to pick at random. In some studies people match "many to one". so you could keep all 3. But the "ideal" approach is 1:1 based on prior studies.
@girlthatcooks4079
@girlthatcooks4079 9 месяцев назад
@@Fralickmike Thank you!!
@ishikahalder799
@ishikahalder799 7 месяцев назад
🤩
@noidea1234100
@noidea1234100 Год назад
Didnt't understand anything.
@user-oj2bu6sv3n
@user-oj2bu6sv3n 8 месяцев назад
Very good lesson except that you are extremely fast. I wish you could slow down your pace
@Fralickmike
@Fralickmike 8 месяцев назад
Thank you for feedback. Note you can slow the speed to 0.75 or 0.5 to slow it down
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