Propofol is an IV anesthetic with strong sedative properties. It acts via potentiation of GABA in the brain. This decreases membrane excitability and ultimately inhibits neuronal activity, making it a useful agent for reducing pain and inducing sedation. One of the most important side effects of propofol is profound hypotension due to reduced systemic vascular resistance and depression of myocardial activity.
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22 мар 2020
