PubMed: Search a PICO question (Demo 2) 

The Question: In infants (P), does the measles-mumps rubella vaccine (I) cause autism (O)? The final search strategy using PubMed's advanced search builder was: (((((-Vaccines-adverse effects-[Mesh] OR MMR vaccine)) AND (autism OR autistic disorder)))) AND (cohort study OR case control stud* OR case series OR systematic review). There are many strategies that could be used. Experiment to see what works best. At the end of the video, multiple search strategy examples are shown with the numbers of results for each.