Pyrrole Disorder & Low Stress Tolerance

Courtney Snyder, MD - Holistic Psychiatrist

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In this video, I discuss pyrrole disorder - one of the most common nutrient imbalances in brain-related conditions affecting adults and children. Elevated Hydroxyhemopyrrolin-2-one (HPL) in the urine, often referred to as “pyrroles,” has been associated with depression, anxiety, schizophrenia, bipolar disorder, autism, ADHD, learning disorders, substance use disorders, and violent behavior. Here, I address:
1. How pyrrole disorder relates to other “root causes.”
2. What we know, what we don’t know, and why this topic is controversial.
3. Causes.
4. Zinc and B6 depletion and how these impact brain health.
5. Brain and physical symptoms and traits.
6. Treatment.
7. How low-stress tolerance can impact one’s ability to pursue meaningful education, work, and relationships.
To learn more about this and other factors contributing to brain symptoms or to receive these newsletters in your mailbox each week, visit www.CourtneySnyderMD.com
Related Resources:
Pyrrole Disorder Symptoms List
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Zinc & the Brain
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Discerning the Mauve Factor, Part 1
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Discerning the Mauve Factor, Part 2
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RCCX Theory, Hypermobility, Mental Health & Complex Chronic Illness
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Medical Disclaimer:
This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your own physician for any medical issues that you may be having.

Опубликовано:

18 сен 2024

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Комментарии : 29

@dzzzzzz1 2 месяца назад

I’m am shocked… All the puzzle pieces are falling in place it seems… I had most of these diagnosis in my life till date but no one diagnosed it under one umbrella I am wrapping it around my head slowly…

@courtneysnydermd-holisticp3072 2 месяца назад

Thank you for commenting on this. I hope something here helps you find your answers.

@dzzzzzz1 2 месяца назад

@@courtneysnydermd-holisticp3072 yes of course Three years ago I came across the term “hyper mobility” during a rheumatologist consultation. He dismissed any issues with my health. Mind you I was unable to stand for good fifteen minutes at a stretch due to my fibromyalgia flares So Sensitivity to light and noise, fibromyalgia, hyper mobility, sensitivity to fabrics and smells. Easily triggered and isolation. … Would Pyrrole by considered under Bipolar Disorder? Wondering 💭 Please advise

@susanwilson4069 2 месяца назад

What type of zinc is best for pyrrole disorder?

@courtneysnydermd-holisticp3072 2 месяца назад

@@susanwilson4069 I wouldn't necessarily say that one form is better, however I usually use zinc picolinate because it is the best absorbed.

@criticalthinker72 2 месяца назад

Well there is. Highly Sensitive person also. Which already makes your whole nervous system more sensitive especially to this chaotic world we live in

@courtneysnydermd-holisticp3072 2 месяца назад

Yes. I agree. I think for those of us who are highly sensitive, there's a lot more that we need to do in these modern times to find calm.

@Needless2say 2 месяца назад

How many of these people with so many health issues are suffering from the SAD diet that modern farm8ng practices in growing that Phood.

@courtneysnydermd-holisticp3072 2 месяца назад

@@Needless2say I agree diet (and the nutritional quality of the food) can be a factor, but usually there are other factors that appear to be at play that are driving pyrroles up (and secondarily decreasing B6 and zinc).

@Truerealism747 Месяц назад

@courtneysnydermd-holisticp3072 stress from the symptoms will send us in a spiral to once we're in the cycle?

@courtneysnydermd-holisticp3072 Месяц назад

@@Truerealism747 I'm not quite sure I'm understanding your question, but glad to response if you'd like to clarify.

@CreativeFlowWithJo 2 месяца назад

Thank you so much for sharing this shocking and important information. I wish I could have learned what you’re teaching decades ago.

@courtneysnydermd-holisticp3072 2 месяца назад

You're welcome. I understand that feeling. It took me many years to come across information that was especially helpful on my own health journey. Thank you for commenting.

@Capri-x8m Месяц назад

Thanks for getting more information about this condition out there. I tick nearly all the boxes for it, according to online questionnaires I've done. Have you noticed patients presenting symptoms of high inflammation with pyroluria? I often have scalp pain, despite an anti-inflammatory diet. I wonder if there was a connection between inflammation and pyrroles.

@reesecup6915 2 месяца назад

Great video. Thank you! Can you do a video on Gilbert’s Symdrome and Pyrolle. I am seeing some Doctors say these are related.

@courtneysnydermd-holisticp3072 2 месяца назад

Thank you. If you can share with me the information you're seeing, I'm glad to check it out. I see a lot of people with pyrrole disorder, but have only seen a few people with Gilberts. While there may be a relationship for those who have Gilbert's, for most with pyrroles, there's another source of pyrroles. Again, I'm glad to look into it and comment further.

@juliuss.5797 2 месяца назад

The thing that shocks me about the pyrrole myth is that researchers have not considered the idea that they should run tests to determine B6 and zinc levels before AND after "pyrrole treatment". It should be no surprise as to why the "targeted nutrients" help those who have mental health disorders, they are literally mental health multivitamins.

@juliuss.5797 2 месяца назад

if you tend to treat people regardless of whether pyrolles are "high or not" then why bother testing at all? the amount of ambiguity in psychiatry "science" shocks me

@courtneysnydermd-holisticp3072 2 месяца назад

@@juliuss.5797 Hi. When pyrroles are especially high, we use EPO (omega 6), avoid omega-3, and use a higher doses of B6.

@AsOfYetUnnamed 2 месяца назад

My guess is that I have pyrrole disorder, and the avoidance of omega 3 is interesting because I've tried different high quality fish oil supplements many times, and they make me feel like I have the flu.

@Truerealism747 Месяц назад

Heds Asperger's ADHD ocd fybromyalgia i have rccx theory is very good and your work to ldn helps fatigue but not pain awake at night all.my life and pain is better at night than day mostly?

@Truerealism747 Месяц назад

Low stress tolerance stress avoidence so this is high what is causing autism ocd

@courtneysnydermd-holisticp3072 Месяц назад

In my experience, there are multiple factors at play with any brain condition (including autism and OCD). I do think RCCX theory helps connect a lot of the dots. Many people I see with autism spectrum symptoms, and OCD have inflammation, mast cell activation (likely due to a 21-hydroxylasevariants), and an exaggerated stress response. High pyrroles (with low zinc, B6 and Magnesium), candida, and mold and metal toxicity are also very common as are COMT or MAOA variants. I'm usually thinking of an alignment of factors instead of one cause

@Needless2say 2 месяца назад

How many of these symptoms are simular to beri beri?

@courtneysnydermd-holisticp3072 2 месяца назад

I think the hallmark symptoms are different, but feel free to comment on the similarities that you see.

@ROMANS3-25KJV 2 месяца назад

Courtney, is your soul saved from hell? All have sinned (Romans 3:23 KJV). The Lord Jesus Christ died for our sins, was buried and rose again the third day (1 Corinthians 15:1-4 KJV). Jesus shed His blood for our sins (Ephesians 1:7 KJV). Water baptism DOESN'T save us (1 Corinthians 1:17 KJV). We are saved by grace through faith, not our works (Ephesians 2:8-9 KJV). Only Jesus saves from hell.