This was the one concept I absolutely could not understand no matter how many times I read the chapter, went to tutoring, watched other videos, etc.. until now. Thank you so much.
Thank u Leah ...surprisingly for every speck of doubt in organic; I'm instantly reminded of your videos and every time you come to my rescue since you explain things wonderfully!
My professors of the past never really handled teaching this well when it came to assigning configurations for more complex molecules (especially cyclic compounds). Your video, however, had me up to speed in a matter of minutes. Thank you! This was a super helpful explanation.
I'm 2 days before my exam and so lost with R and S configuration with organic chemistry THANK YOU SO MUCH you're legend, that's so easy to follow and to understand
Oh wow, so glad this came at the perfect time for you. Make sure to watch the entire series so that you catch all the different ways of solving these problems simply
My teacher barely went over this. Thankyou for this clear breakdown on what to do. I recommended to my teacher to teach the breakdown like this as his lecture didn't really explain why he was choosing the paths he chose beyond one molecule or ring.
Hi Leah.....your lecture videos are really amazing... you made them look so simple even though they are tough to understand. Can you please do a lecture video of converting Newmann to saw horse formula and vice versa....of both a single chiral as well as a two chiral centred carbon molecules??
If I needed help you would be the #1 choice Leah. But I'm just watching for fun. Many thanks for your great videos! I would love to support you by purchasing a kit but the link you give doesn't work.
Thank you so much for watching! I really appreciate the support. I don't see any issues with the link. First, go to Leah4sci.com/Kit and then click on the first linked text that reads "Molecular Visions Model Kit (Amazon)".
Thank you SO MUCH! No one else including multiple youtube videos and even my professor ever adress what to do when the atom is surrounded by carbon chains! It's a real problem if your professor tells you to determine the rotation of all 50 stereocenters of Gargantulide-A for a take home project!
Hey Leah, you're videos are the best organic chemistry resource I've come across online. I went through the Chirality and Fischer Projection videos on your website and couldn't find anything in regards to Diastereomers and Meso compounds other than the cheat sheet. Have you made any videos on those topics? Also, finding chiral centers in complex skeletal structures? Thanks again!
The videos that I have made on those topics are housed in the Organic Chemistry Study Hall. These Study Hall videos are longer and more in depth than the free videos that I share on RU-vid or on my website. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/
How do we decide which secondary atom to count next? In other words, when we’re doing a tie breaker and an initial carbon (bound to the chiral center) is bonded to another carbon and an oxygen - do we count the oxygen or the carbon first?
We actually take all of the atoms (that the initial carbon is bound to) into account. For example, one initial carbon may be bound to an oxygen and carbon while another is bound to TWO separate oxygen atoms. That one would outrank the other, according to Cahn-Ingold-Prelog priority rules, because two oxygens are higher in atomic number than one oxygen with a carbon. For more on ranking substituents according to priority, I suggest taking a look at my full series and cheat sheet at Leah4sci.com/chirality
Sulfur is attached to carbon attached to carbon attached to the chiral carbon. However, since we don't look all the way out on the chain. Instead only look at the atom directly attached and compare. C-O beats C-C-S due to being closer to the chiral carbon
does it matter what direction you go with carbons on the phenyl ring because you couldve gone up and gotten the double carbon bond before you went down and decided earlier it was number 1 priority
Great question! The conjugated system of pi bonds in a benzene ring resonates in a complete circle. That means, no matter which way you go around that ring, you are going to have at least partial double bond character. The phenyl substituent will always outrank the cyclohexyl group.
The Phenyl has pi bonds on all Carbons since the bonds are in 2 spots at once, forming that donut shape (that's why it's drawn with a circle, not double bonds, see Crash Course Chemistry), so that wasn't the best example there. The answer was still the same, but not very clear.
I'm sorry, but I don't offer tutoring through RU-vid comments. For help with this and more, I recommend joining the organic chemistry study hall. Full details: leah4sci.com/join
I have a separate video for that in this series. leah4sci.com/chirality-stereochemistry-enantiomers-diastereomers-r-s-organic-chemistry-tutorial-series/
