Ranking Isaac Characters by How Well They Are Designed 

I think the Keeper is probably the best designed character. He changes a lot of things about the game with buying devil deals and whatnot. I feel like he adds just the right amount of challenge while also being fair.

lilith is a mindless murderer makes her perfect

I'm going to call out that Judas starts with 3 cents, for the 30 pieces of silver he gained by selling out Jesus. That puts him on good design. He also.(used to) have a guarantee deal with the devil every time he used his book. That's proof that he can no longer return to grace. Judas is the persona of himself that Issac most fears, hence why he only has 1 heart.

I’m surprised that Azazel didn’t at least make it to well designed. The only thing I think slightly brings him down is less synrgies.

t laz is literally one of the coolest charachters, as well as jacob and esau, while t. blue baby is super gimmicky on the other hand imo

Tbh t laz has a criative design, even if he is a terrible character to play

Issac is kinda badly designed. His d6 makes the player less resourceful and basically trivializes any run. He’s one of the most boring characters because of that imo.