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Structural Activity Relationship (SAR) of Barbiturates 

egpat
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Activity and duration of action of barbiturates is highly related to the groups at 5th position in barbiturates. Interestingly the total number of carbons, nature of chain, branching and presence of unsaturation all these factors at 5th position greatly influence lipophilicity of the drug thereby affect the duration.
#barbiturates
#phenobarbital
#barbiturateacid

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18 ноя 2020

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Комментарии : 34   
@01shadmanalshakib71
@01shadmanalshakib71 3 года назад
Sir,your videos of SAR of drugs is very informative❤️. Plz make more videos based on medicinal chemistry(synthesis),stereo chemistry, biopharmaceutics.
@egpat
@egpat 3 года назад
Definitely, Soon I will upload more videos on these topics. Thank you.
@sandhiyasaravanan9968
@sandhiyasaravanan9968 2 года назад
VERY VERY CLEAN EXPLANATION WHICH MADE MEDICINAL CHEMISTRY VERYEASY😊
@rengi17dk11
@rengi17dk11 3 года назад
Sir your explanation is the best!
@prof.drjaafarhjmdzain6032
@prof.drjaafarhjmdzain6032 3 года назад
Its very educational and make it easy to learn
@anotherone4669
@anotherone4669 7 месяцев назад
Very helpful and informative
@gopinathnarayanan9069
@gopinathnarayanan9069 3 года назад
super explanation.
@hanasilewnet2320
@hanasilewnet2320 3 года назад
Thank you very much
@pundikrishna2136
@pundikrishna2136 Год назад
Good presentation sir p krishna
@sonalipatil5008
@sonalipatil5008 2 года назад
Thanks a lot
@TheBeresford7
@TheBeresford7 Год назад
Barbiturates are an awesome example of what the power of simple carbon chains can do for a molecule , the ring / ketones are obviously the functional parts but without those elaborate carbon chains the molecule is useless
@tashoi876
@tashoi876 Год назад
EXCELLENT VIDEO!!!!
@egpat
@egpat Год назад
Thank you very much!
@praveenkumar-jd1zl
@praveenkumar-jd1zl 3 года назад
Nice explanation ,sir pls make video about anthelmintic
@egpat
@egpat 3 года назад
Sure.
@user-dt2wu9zo9r
@user-dt2wu9zo9r 3 года назад
my question is if we have alkyl on position 1 the activity decrease or increase?? please answer me
@hanasilewnet2320
@hanasilewnet2320 3 года назад
N alkylation increase anticonvulsant activity and large alkyl have sedative hypnotic effect and only one of N can be substituted
@user-dt2wu9zo9r
@user-dt2wu9zo9r 3 года назад
@@hanasilewnet2320 thank you very much 🌼🌼🌼
@ceepeeverma7130
@ceepeeverma7130 3 года назад
nice
@notebook4978
@notebook4978 2 года назад
Amazing sir
@egpat
@egpat 2 года назад
Thanks and welcome
@prisinha
@prisinha 2 года назад
5:05 factors contributing to duration of action for Barbiturates
@ImtiazAsim
@ImtiazAsim 3 года назад
Make more videos on SAR of drugs.
@egpat
@egpat 3 года назад
Sure, Keep watching.
@sayanikundu8854
@sayanikundu8854 3 года назад
Sir plz make a video on sar of Bzd
@egpat
@egpat 3 года назад
Already uploaded earlier. You can find here. Thank you. ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-kfPlnwZG7b8.html
@prisinha
@prisinha 2 года назад
3:44 Risks of Monosubstituted
@Saleemsan
@Saleemsan Год назад
Needs synthetic methodology
@abhirathod9778
@abhirathod9778 2 года назад
Sir 5 position on methyl grup not ethyl
@newworld.com88
@newworld.com88 2 года назад
How u told 3-4 carbons sir
@newworld.com88
@newworld.com88 2 года назад
Any one Reply pls
@VnoSelva
@VnoSelva Год назад
Same doubt
@jatinjadav1097
@jatinjadav1097 Год назад
@@newworld.com88 I think Unsaturation of Carbon Atoms formation of pi bond that makes electrons less available..
@martinatravnikova7959
@martinatravnikova7959 3 года назад
0:17 virtual-chat-girls.online
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