What type of experiments should we be carrying out on RoboColumns? Which ones are important to us?
Luke Cach of Synthace discusses DOE design and how to facilitate Design of Experiments on Repligen RoboColumns - from experimental design to structured data analysis at the end.
Scientists are often bound by feasibility. "Will my experiment work in the lab with my equipment" rather than "what is the best possible experiment I can run?"
DOE adds an additional layer of complexity, taking into consideration all the factors at play and how they impact each other at the same time. The good news is, DOE doesn't have to be difficult, and anyone can now run powerful DOEs, easily.
Not only does DOE result in a better, more powerful experiment, recently there's been more and more of a push from regulatory agencies to implement QbD methodologies, explicitly DOE.
These regulatory agencies expect manufacturers to use DOE and identify and control their CPPs and critical quality attributes.
Synthace can easily run RoboColumns experiments on your Tecan devices, from building and simulating workflows, to running your lab automation and executing the experiments, to structuring your data and mapping out results for quick and easy analysis.
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29 май 2023
