The Anatomy of THC 

CLARIFICATION: At around 07:00, Justin misspeaks. THC has an inhibitory effect on the POMC neuron, causing LESS GABA (the neurotransmitter being secreted) to be released. The CB1 receptor is indeed stimulated, but in his excitement he made it seem as though an excitatory signal is being sent through the POMC neuron. Oh Justin.... Thanks to the user @Potatomanure for catching the flub!

Let’s all have a moment to thank our hearts, lungs, and liver for handling things our mind and soul couldn’t.

I’m new here thought this was a weed channel. Bro started pulling out real body parts like I’m too high for this rn

In school health class they used to show us cigarette smoker vs non-smoker lungs. I’d be curious to see a comparison of those with an exclusively THC smokers lungs

I started eating edibles after I got breast cancer. I do a blend of Thc and cbn. Cbd is a sedative that curbs anxiety. 5 mil a day for me. Just a small amount to let it do it’s work. I also have chronic pain and this has gotten me off of three prescriptions.😄

Always trust a guy who says we fully don't understand. He's honest and wants to learn

I used to vomit 15+ times a day after chemotherapy. With one joint. I was healthy and alive af

If you are looking to treat symptoms of a mental health condition I'd recommend psychedelics.

I think one of the most interesting thing about the endocannabinoid system is that is ubiquitous: we are finding proof of cannabinoids modulating the immune system, the digestive and secretory ones, among all the others we know about. Fitocannabinoids are so fascinating especially for their adaptability and evolution coherent with the progression of the various apparatus and system of mammals. And so I really hope cannabinoids will get to be used more in treating a large plethora of diseases and conditions, also giving us other perspective of the neuromodulation they are involved in. Great video as always!

Watching this while smoking a joint. I now feel both scared and educated

THC: *interacts with cell Cell: bruhhh

This video lasts around 10 mins and not for one second I am bored or wanted to stop….awesome 👏👏

Honestly I wasn’t bored at all throughout the video and I was paying attention.Thank you for making it Interesting and informative at the same time, looking forward to more vids

I'm on medical THC for my spinal injuries and arthritis, this is by far the best medication I've been on, it's made my life somewhat normal again, I can now sleep and wake up fine with no side effects, I was on morphine and other drugs for 14 years, I had terrible side effects and lack of sleep,

I can tell you that long term use is wonderful, Lol. Started at 14 and now 61. The strains are powerful as hell now. I was smoking it back when it was called ditch weed or alcapolca gold. I feel fabulously 45, aside from a few aches and pains of natural body aging. Health is good. Eyesight; last year they put a hole in each of my eyes just outside the color part due to hypertension. My eyesight is good for my age but has improved since my eye pressure has been reduced. I graduated high school 5th in my class at age 17, had a great career (retired at 56), raised a family as a single parent and now a Grandmother. I have always had munchies. To combat that - drink warm tea or lemon water and munch on low calorie things like sugar free jello, salad, etc. - then you can eat until you can't. Stay away from sugary sweet things, it's not easy, even I have to have a spoonful of honey that magically turns into 4 spoonfuls, Lol.. Not sure if anyone will read this or no - but if you do and got this far .. don't let anyone tell you you will fail if you partake, you won't. Don't let anyone tell you it will affect you weird or harmful when you grow older, it doesn't. Don't let anyone tell you that you won't amount to much because you partake, because you will develop wonderful creative skills that allow you to cope in the harshest of situations you will run into, in your lifetime. Eat organic foods when you can, drink clean water always, don't eat too much meat, live and let live (others have the same rights you do), don't get uptight over those little things - You will go far. As a 48 year partaker - if it is meant for your body to continue using, your body will tell you and you will know if it's for you, but keep in mind, it can become a long term medicine. *Cheers*

Great explanation. Thoroughly enjoyed your relaxed way of communication about the "side effects" of THC. I would love to see a video about the power house Mitochondria and the effects of the THC levels...

this is the best way to teach, i watched the whole vid thoroughly and actually learned more and remember it wen it’s said this way

Don't let this distract you from the fact that mitochondria is the powerhouse of the cell.

As a smoker this was so much more educating than any drug class ive ever seen. Its so interesting to see how munchies occurs and how dry mouth isnt just the bases of smoke itself.

I would love to be donated for science and education or for doner organs. Thank you so much for this wonderful and fun educational channel. A true beacon of light on this platform.

I’d love to learn more about how THC, CBD and terpenes effect our bodies longterm and what causes “stoned forgetfulness”. These videos are educational and amazing! I would be interested in learning more on how drugs in general impact the brain

Maybe because I’m stoned but that heart you held, was someone’s life. Someone’s lover, father,sister, daughter etc. they were probably loved, probably are missed and here you are teaching me about thc with it. Love it

I have never been more grossed out and absolutely transfixed at the same time. Should I stop smoking? Should I take another hit? Nobody knows.

I run a sales floor of a dispensary in Canada and found this very informative. Very interesting stuf, presented well.

This is very helpful and educational! Please do more on this subject.

Once he pulled a heart out I knew this shit was getting real

I can't be the only one smoking while watching this, saying "damn that's insane" while exhaleing

Love the video, Very informative. People should know more about what they put in there bodies, as you said there is still so much we don't know yet, I appreciate the fact that people are now studying the effects and letting the people know especially since cannabis is widely used.

Definitely want more of you talking on cannabis and TBI and other nerve damage. Love you peeps!

Marijuana content that’s actual content and educational vs pothead science? Y’all I thank you from the bottom of my heart for this

I love your videos! You are breaking down something so complex into something understandable. Thank you for doing these. I would love for you to make one on the effects thc has on the brain. Chemicals released, how different regions are effected during the high.

I use CBD for chronic pain. I'd like to see a video comparing effects of THC and CBD. Thanks. Love this channel. If we had this kind of learning in high school, I'd have gotten much better grades!

I'm the Head of Research for Elixinol Sub Saharan Africa doing my professorship in Endocannabinology under Dr Phillip Blair and I'm greatful for you using your platform to bring validity to this field 🌱

I get very anxious when I smoke only if I have obstacles I need to handle in my life. When everything is going well in life I become happy and chill and live in the moment. If you must smoke, handle your responsibilities first.

Awesome video. Great stuff thanks Justin

Hi, I am also a Human Physiology student and I am really watching your channel for my knowledge purpose. And as you asked I am really interested if you can make a full video about the cannabinoid receptor types and some of the signaling system.

I’ve never been more disturbed and more informed In my entire life, thanks?

Explaining how people build tolerance, as well as how you can lose your tolerance and why would be interesting. I also think talking about sativa vs indica and how they affect you differently would be super interesting!

Love to see more of these - I would be super interested to see a video on the endocrine system/HPA axis!

Thank you for this. I live in Canada where prohibition is only a bad dream in the past now. I really grasped all that you explained using the body parts. It's one thing to be told these things but I feel you really brought it home with how you explained and used your human examples. I completely surprised my doctor after consuming some edibles and waiting for the high blood pressure to lower blood pressure transition to occur. She was happily surprised at the results. I have moderate high blood pressure and am taking pharmaceutical medication to control it, but I am hopeful that science can all of us the same results without the pills, possibly using micro dose levels of Cannabis to moderate instead. There is so much to learn about this plant. You mentioned that Cannabis affects all the body organs. I would like to learn more about the effects on liver and kidneys, since they all have receptors. Could it be that Cannabis is fixing, tweaking and repairing us as we damage ourselves from the world we live in?

"Ya fam just chop my skull in half and educate people on that dank".. Hell of a talk to have before you go to the other side

Cannabis is pretty big among the body building community due to it's ability to over emphasis what's called "mind muscle connection". Having a greater connection to the muscle with the brain and not just moving weight, apparently has the ability to increase muscle growth. I would love to hear a deep dive about this.

Wow! amazing! I wish you were my teacher back in nursing school for all those pathophysiology classes!!

I’ve seen dozens of AMA physicians for my gastroparisis and what that got me was on 14 different types of lab created pills, patches and treatments that did everything but work with my body. Then they introduced Fentanyl. What I have learned though this process is that natural remedies work best, hands down. I was 50 the first time I ever tried cannabis for pain relief and nausea and that changed my life. I am no longer on any of the petroleum based prescription products and have my life back now. I’m grateful to see the stigma of CBD and cannabis changing and hearing story after story of how lives are improving with the use of plants.

i don't get red eyes, its a super power to stone during a family gathering and no one can tell.

i am dead weak at the fact this man is just holding someone’s throat in his hands 💀🤣🤣🤣

I love how educational this video was, a lot of us have learned new interesting facts thanks to you. Could you make a video about how to cleanse your body from thc?

One of the most educational and interesting videos I’ve seen! Being high while watching was worth it 😂

I'd love to see the lungs of a avid cannabis smoker, vs non smoker, vs Cigarette smoker.

“That’s why your eyes don’t get instantly red” Dabs: “am I a joke to you?”

Magnificent, i've looking for info like this, all consumers must see it. Thanks;)

It was startling seeing the way he held a human esophagus so nonchalantly.

Not sure if you’ve done this but it would be really interesting if you did a video on the physiology of mental disorders such as bipolar disorder or schizoaffective disorder.

I bet most of us lit up when he mentioned the mitochondria. We've been trained since middle school for this moment. It finally came naturally.

No wonder why I love the so much, it goes to my heart almost instantly

I'm glad smoking can trigger my anxiety for the first few hits and this definitely help with understanding why and what's going on . Keeps it controlled

"to celebrate 4/20 we gonna have a look at the cadavers" not what i had in mind for today but ok

This is fuckin trippy dude I'm on some edibles right now and my guy is straight whippin out body parts 🤣 He wasn't playing any games about the whole anatomy part LOL

Bro I've never been so geeked about this😂😂 this makes so much more sense to me now😂 plz keep educating ppl cause this just made my entire day🫶🏽 I used to love learning about the body back in high school😅 just so interesting and I love you guy's channel, keep it up🙌🏽💙

Currently watching this high while eating a bowl of cereal. I honestly feel like I’m high in science class eating a bowl of cereal during a lab 🤦🏽‍♀️😭😂😂😂

Great explanation. Could you do a video on opioid addiction (toxicity and withdrawal symptoms)? Thank you. Have a nice day.

As a THC user: why do Delta-8 and Delta-9 products have different dosage recommendations but also very different effects (for me anyways); educating the public how to use these products is amazing ❤

Im nursing student in México (yeah, the nursing its for men also) and there arent many studios of the effect of these cannabinoids and i think it is very important to have knowledge of these components because the cannabis consume has become popular and having that knowledge will help a lot to understand how it works in our body

I learnt more about science in this video than roughly 14 years of 1-2 hours of science every day.

Dude, I'm pretty loaded right now and most of what you said went right over my head.

Thank you, Your knowledge is greatly appreciated.

Great footage. Yes I am interested in learning more about the endocannaboid system, have you uploaded yet? As always, nice work…

This man literally just taught me more and 9 1/2 minutes than I did in anatomy and physiology

I got severe PTSD and it helps everyday, i can day dream, i can laugh, i allow me to think freely, i love it, it saves my life.

My brain was reacting when you started poking the hypothalamus with that tool. I got the chills man. Lol

Hi Justin, just saw your video. Idk if you heard for Doctor Melamede, his sources may have a lot about cannabinoid system. I would be curios to know more about "eating" thing, since I dont get instantly hungry anymore... WHen I started to smoke I used to get hungry (especially for sweets) instantly and now I barely see the difference when I smoke.

I can't believe we know so little about something that is so commonly used at this point! I would love a video on how and why we get anxious sometimes when you consume thc.

Is no one gonna talk about how this man just had access to hearts and throats

Any new info is good info I’ve been needing to know more about the human body and very interested in how it actually works

Mannn, going to this cadaver lab was the coolest field trip I’ve ever been on 🤯

“Hey let’s talk about weed, don’t mind these corpses behind me”

This stuff is so cool. Now when I smoke I can actually visualize what’s happening in my body and that is so trippy. You’ve taught me a lot! And have inspired me to stay away from alcohol after seeing your video about it.

Amazing that this little plant can do so many wonders for out bodies and mind!

Always good to receive scientific info

I'm an organ donor and hope that my body is used for something cool, possibly educational. However having my head cut vertically would be pretty metal.

Justin I am a medical assistant and there are soooooo many videos that I would like to see.Seizures, female vs male orgasm, the fear mechanism, the effects of PTSD/Trauma on the brain, mental mapping (knowing where you are and how your body is positioned in the dark), the adrenaline system, the CNS in its entirety because it’s my favorite and so much more!

Excelent documenten. You now have a new suscriptor.

I think some more videos on THC and CBD on how they affect the body over long term would be amazing

I'd love to learn about the effects of marijuana smoke on the lungs and trachea vs smoke from cigarettes or vapes? Is it as harmful to the lungs as cigarettes? Chronic vs occasional smokers. Thanks!

My mind was blown upon learning where the salivary glands are located. It now makes total sense how you can actually feel saliva being made around the back of your jaw when your mouth waters.

Honestly, i learned not a lot for how long this was with your clear high level repertoire of knowledge about the human body. Granted, it was only a what, 12 minute video or so? Endocannabinoid video idea is FIRE 🔥🔥🔥 Off topic note, i dont get munchies from THC. Many do. Maybe its just mental discipline?

This was a very interesting video!! Thanks science and to this guy.

Whenever I stumble across your videos, they never cease to inform me of something new. Can’t help but click on it when they pop up

I smoked weed for 30 years. From the age of 13 to 43. I was a daily smoker. I quit smoking a few years ago. When I quit… absolutely nothing happened. I didn’t get noticeably healthier. My life didn’t get better in any way… or worse for that matter. I don’t know what this means exactly. It’s just my experience.

Me encantó tu vídeo, me gustaría saber ¿Qué daños a largo plazo puede provocar en cannabis a tu cuerpo?

Really enjoyed this!

A few things I would like to see: Effect on cognitive abilities Effect on lungs Effect on memory Effect on inhibitions

All this interesting stuff aside, this channel is my new fav, i grew up with a nurse as a mom so as a kid i found it easy to memorize anatomy. I love this stuff. keep it up sir.

Thanks for the valuable information team 👍🏻

I would be really interested to know more about the long term affect of the munchies. When I started smoking I would get the munchies and it didn't seem to matter what strain I smoked but I've noticed in the past few years it actually suppress my appetite. For example it became apart of my routine having a quick puff before supper and minutes later I had absolutely no appetite, even if I was starving before hand. Knowing I had to eat something I would still eat but it was nauseating. A good friend of mine who had been smoking longer than I have was having issues with appetite as well, which lead to other gut health problems. She tried a few things but eventually decided to completely cut weed out to see what would happened. After a week she got her appetite back! I guess what I'm getting at is does long term use maybe have the reverse affect? I only noticed this since it became legal in Canada and was being sold legally. Maybe what ever they do to mass produce it vs home grown has different side affects? Love the channel btw! You make learning anatomy fun!

I read the title as “The anatomy of THICC”. I was confused but accepted it as a legit title.

I'm reaaally looking forward to the full series of how cannabis affects everything in our body. I immediately thought of an idea of how different strains affect the body - ie. Cannabis Sativa & Indica. Perhaps a separate video could be dedicated to that. Thank you for everything you do.

I am so happy u made this bc It just proves smoking that fire is not bad Keep do ur thing…. ❤❤❤

Great show!

When he split the heart open. I lost my high. Had to smoke again after this 😂