Go to meetfabric.com/MODERNMBA and start investing in your child today. 0:00 Unprecedented Virality 3:01 Sponsor Break (Fabric by Gerber Life) 5:00 Big Pharma Deconstructed 14:37 Eli Lilly 25:01 Novo Nordisk
An even dirtier business around weight loss is weight loss supplements that have little to no regulation around the burden of proof for their claims. The supplement industry as a whole has this issues around poor regulation and poor scientific backing.
Supplements have been under regulated in many countries for way too long. Meds go through an arduous process over a long period of time; supplements don’t. Still there are bozos who trust supplements more than medication.
7:00 You say that government couldn't afford medical R&D, but this is completely backwards, governments could easily foot the bill and are uniquely placed to do so. With access to low interest loans, bonds, the ability to create money, and a guaranteed income from taxes, governments are perhaps the only institution with the resources and the long term vision to invest properly in medical R&D.
You trust the government that wastes billions of dollars to be the captain of a 7 trillion dollar pharma R&D budget? The pentagon was purchasing $14K on toilet seat lids. Get a hold of reality
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I really don't get the whole "no government could foot the bill for drug development". Your given example is a 1 billion dollar drug, but the US budget is over 6 trillion, so 6,000 times that amount. Surely the government could spare 0.1% of its funds for drug research. And don't the Covid vaccines just entirely fly in the face of this idea as they were largely developed with government funding?
1 billion per succesful drug. You are not considering all the unsuccesful drugs. So its more of a 100x factor. The true cost innovation means that there will be a lot of losers.
For every 1 billion to develop a successful drug that may or may not be useful, 10 billion goes down the drain. There are currently 7,000+ drugs in development. That’s 7 trillion dollars
I was hit by a car and was in the hospital for 2 months, in acoma for one of those months. Got out of the hospital and do to my injuries my movement was limited. I went from 170 pounds to 245 pounds in 5 months. Then I started drinking only water and black coffee and eating only fresh fruits and vegetables, eggs, some fish and other meat. No bread, no sweets, no soda or juice or processed food at all. It was like kicking drugs for the first month or so, bad mood swings and messing up here and there. But after I got used to the diet, kept pushing myself to eat only what my body needed to be healthy. Now I am to the point where my guilty pleasure is eating too many raisins instead of drinking 3 cans of soda and eating donuts with icecream. I am currently 165 pounds, add in the fact that I couldnt work out really because I was recovering from my injuries and you will realize its pretty much all diet. Its been a year and nine months since the accident so I am able to work out now, but in the beginning I only went for walks and did yard work for most of my weight loss. Just have discipline and patience when it comes to diet and you will get to where you want to be. Also keep in mind that a diet is not a thing you do for awhile then go back to eating how you were. Its a lifestyle change and its for the rest of your life, keep that in mind. I use to think I could never give up certain foods, now I couldnt imagine ever eating them again. Nothing processed, just fruits, vegetables, eggs. Save a lot of money also. Btw, fast food needs to be eliminated all together, there is no excuse to put that poison in your body.
He literally went over it in the video. “PBMs have an incentive to promote the drug that gives the most rebate, not necessarily the drug that is the cheapest or the most effective”
Shareholder wealth should not eclipse keeping people alive. When a primary wage earner dies due to inaccessible treatment often the entire family collapses into poverty and society pays the price to assist. Privatized profits, socialized losses.
I didn't know about the insulin backstory, I thought insulin had been around for decades and was not expensive. To anyone wanting to do weight loss properly, just quit all processed foods, all added sugar and all animal products. Yes this will make you a 'closet vegan' but, once you get into cooking from scratch with mostly vegetables, you will wonder why on earth you ever ate that other stuff.
These types of drugs (GLP-1s) have been on the market since 2005. We just didn’t hear about them ‘til Ozempic, and celebrity use and TikTok influencers.
What a great subject! I know a bit about pharmaceutical research in general from my studies, but not as much on the details of the business. Big pharma is def not to be trusted in terms of doing what's best for the health of the consumer, as it is a business with the singular goal to make money (like everything in the US where it's unfortunately often at the detriment of consumers health/psychological well-being, environment, and/or animals/people exploited to make the product/service). Thanks for the info, appreciate this channel
You really screwed up the insulin section. "They had no choice"... Do you think diabetics just died before these new fancy insulins came out? And its not patents limiting generics for biologics. Its biosimilar approval. Biologics are not like drugs. You can't just show it's the same molecule, like a generic drug can. The molecules are far too complicated.
If it was that easy there would not be a industry around it. Want to make more money, work more hours. Want to get to the destination faster, drive faster. Yes, it works, but life is often more complicated than that.
