The RAS / RAF / MEK / ERK Pathway Part 2 

You are literally the best at this across the entire internet

clear, concise, great drawings. This video series has helped me immensely. Keep up the great work!

Your videos are SO helpful. Thank you!

Outline: - explanation of Grb2, SH2, SH3, SOS, Ras and Ras variants - structure of proline amino acid - explanation of monomeric G proteins (on / off states) vs. heterotrimeric G proteins - background of RNAPII, transcription, pre-mRNA, exons, introns, splicing - structure of isoprene molecule, cysteine amino acid, farnesyl group, thioester link

You are amazing, thank you so much!

your videos are really very good....

Hi Elliot, great video. One minor thing however, next to KRAS and NRAS is HRAS and not BRAS (at around 16:40). Probably confusion with BRAF :-).

elliot, you're the GOAT

I think you mean HRAS rather than BRAS

nice explanations

You are too good, I wonder r u a lecturer or any kind of professor? How many years have you been studying this? Brilliant work

Son of sevenless is named after a homolg found in drosophila...my lecturer loves flies :/

I think it's not the coding strand that's read by RNAP-II but instead the template (non-coding) strand. The pre-mRNA is complementary to the non-coding (template) strand but is identical to the coding and so is used to code for amino acids when the bases are grouped as codons.

If I pass my examination of molecular biology 'll send you a Christmas bonus

ERROR ----- HER2 is an orphan receptor and does not bind ligand. Such an elementary mistake.

how can one person know so much? :D