Thymosin Beta-4 for Musculoskeletal Healing 

(Success story) Just wanted to let everyone know my experience. I had a full achilles rupture that I got surgery for. I started using BPC 157 and TB 500 one week post surgery. I just went in for my second follow up today (6 weeks post op) and I'm ahead of the curve so much my ortho has taken away my crutches and started me on pt early. The original plan was to start pt around 8-10 weeks, so that's 2-4 weeks shaved off already. Plus, he's certain at this point I'll only need 4 weeks of pt before they can cut me loose to finish on my own in the gym, at home etc. This was my first experience with peptides, and I would absolutely 100% recommended that anyone hesitating to use them bc of uncertainty should take this as a sign to go for it! At this pace, I will be fully recovered in less than 6 months vs the typical ~1 year it normally takes. Dr. Timmermans was a huge help in advising me along the way with simple questions I had, so BIG TY to Dr. Timmermans!! 👏 And just so it's said, I'm not being paid to say this nor compensated in any way. I'm just excited about the results and hope that I can pass this on to help someone else. If you have any questions about my journey so far feel free to reply to this comment and I will do my best to respond as soon as possible.

Thanks for the video

Great presentation Doc!

Fantastic. Thank you.

Wow! Good piece of info! I was wondering why I was paying more than double for my tb500 than where I see it elsewhere. Turns out I was buying tb4 the whole time! Thanks doc! This is great and I have plenty of people to share this info with.

Thank You Dr. Drew!! I like the info and the Presentation!! Can I ask , would this help with ulcerative colitis?? Thank you for your time.

Useful and to the point info. Thanks! Question: I noticed you mention that Tb4 inhibits osteogenesis. So, Do you think that Tb4 would be contraindicated for people who have AVN (Avascular necrosis / osteonecrosis) of the femur head? Would BPC-157 work better? Or....?

First of all, thankyou so much for your video, it allowed me to discover Thymosin B4, understand it and then decide to order a vial of this peptide online. I'm currently using BPC-157 on a scheduled 2 week cycle, injecting 0.2ml subcutaneously every night to help treat disc degradation I currently have in my upper cervical spine (confirmed from an MRI). If I am to combine BPC with the use of Thymosin B4, what would be your recommended dosage? Thanks in advance 😁

Does the heart regeneration effects come from frags 1-4 or 40-43? I’ve read 1-4 is progenitor cells whilst 40-44 is embryonic cell migration.

I'm 12 weeks post double open femur fracture and 5 weeks post bone graph (doner femur marrow and stem cells, plus cadaver bone). I plan to take BPC 157 arginate and tb-4 fragment to help with inflammation, ROM in my knee, scar tissue, and muscle regrowth. Is the tb-4 fragment okay to use in regard to my bone graph?

It showed synergy with bone marrow stem cells, much more angiogenesis n so on

I just came across peptides, no one ever mentioned them before and I've had ever type of injection procedure on my neck to fight cervical dystonia. I know there is no way to know how this will help combat that condition but inflammation is insane on the right side of my neck scm is pulling tight, could be spinal accessory nerve injury that can't be properly diagnosed but I was hoping to reduce the pain.

Thank u doc, local( my injury is in the sopraspinatus tendon )subcutaneous injection are fine?

Hi Drew, What's your opinion / experience if any with TB4 in regards to healing heart damage from mycordatis or similar conditions affecting the heart. I've read some studies which seem to indicate a positive effect in repairing damage after a heart attack but I'd like to collect a wide array of information before making any decisions on treatment. Thank you

Drew your videos are super informative, also had a question… Just had an MRI (with arthrogram) and it shows a labral tear in my right hip, I think I’ve had the clicking and minor pain for a year or 2 but in the last 6 months I had to stop going to the gym, gave up running and hockey cause the discomfort / pain was unbearable… Im 26 years old from Buffalo, New York and local doctors recommend I get surgery. Should I consider taking bpc 157 and rn 500 before the surgery or use it as a post surgery treatment ? Thanks in advance .

Is tb4 safe for the heart ? As I was diagnosed with pericarditis inflammation around the heart and nothing helping me to heal now I’m looking into tb4 thanks

Very interesting, curious to know if this would work in treating endometriosis related pain and inflammation?

One other question: How are you stretching one vial for 20 days? I've read all over the place that these two peptides only last for 7-14 days once reconstituted?

Very informative video doc, i tore my patella tendon in my left knee last year in may, i can do pretty much everything again but it just doesnt feel the same as my right leg, it is also smaller and less strong then my right leg. What would you recommend me to use and what dosage in order for me to get it back to atleast 95%

Thanks for this very interesting, and easy to follow. Is there any oral version of TB4 (any alternative to injecting, or would an insulin pen be suitable)... Thanks again!

Do you treat back pain? I got a chiropractic injury 6 months ago. Chiro jacked my back up after 7 weeks of twice a week HVLA type thrust movements in thoracic region. MRI showed hemangioma but no apparent herniation (crappy underwater looking MRI though) Tried a 15 mg 1 month course of BPC, did nothing. Now a few weeks into CJC/IPAM. All prescribed through TRT clinic, compound pharmacy sourced. Not sure if I had a small herniation or what the heck. Following your 2 kg protein per kg of Bw, 10 grams collagen 3 times daily in beef bone broth with vitamin C each time, Secretagogue cjc/Ipam TID 100/100. Keeping diet clean and 18 hour fasting 3 days a week. Anyhow, curious if you treat thoracic back pain in your clinic. Also, I heard on a podcast with Stuart McGill that you don't want vascularization and I believe therefore innervation within a disc, increasing the potential for discogenic pain. What's your theory on treating a herniation with BPC or TB500? Could there be a potential for a non-ideal vascularization in structures outside of what you typically hear about such as tumors etc? Loaded question. But I find the field you are in very interesting. I'm a cardiac sonographer, and I've been on underground forums since 2014-2015 and I've heard tales of guys being on something such as TB500 and having a heart attack, but there body having been collateral vessels, mitigated much of the ischemic damage to the heart tissue. I've tried to bring this up to cardiologists but alot are old school and just know what they were taught, what they currently do, and what makes them money lol Thanks for the videos Doc, keep it up!

Is it safe? I am scared of side effects. Are there any dangerous side effects?

I have a partially torn ACL and torn meniscus…. I’ve been taking TB4 and I honestly can say that my knee feels more stable than ever since I had the injury. Not sure if it’s a placebo thing but it definitely feels more stable.

can rubbing alcohol kill the Peptide ??

What dosage would you recommend for a ligament injury in the wrist? Is it ok to mix TB 500 with BPC 157?😊

Anyone tested this ?

I am looking to cure receding gums and tooth decay - I have a cavity under the gum line - only seen by xray. Will anything work?

Doc, thank you for your excellent videos. I have learned a lot over the last few days of watching. I was recently diagnosed via MRI as bone on bone in my hip. What do you know if anything about BPC, TB4, MK-677 as a stack to try to repair that level of damage. I am currently taking 3 grams of Vitamin C, 20 grams of collagen, Bio-Sil silica, and Baxyl HA. Thank you in advance.

I have a bad knee. Should I take TB4 before I have my PRP done or should I wait until after I have the PRP?

I read research that shows tb-500 half life to be very small, near the end of the video you mention front loading tb 500 for post procedure, does the short half life matter in the context of healing?

Hey , i have a partial forearm and bicep tear no surgery needed but super slow recovery how do i use this and for how long?

Would you use the same dosing protocol for frag 17-23?

Question: Recent severe DVT in lower leg big vein (with PE) and fear the scar tissue buildup causing long term valve issues and the accompanying claudication. The little I've read on TB4 suggests it might help healing and vascular regrowth. (PE didn't kill me and being active is super important to my lifestyle, this is really about the lower leg health, am on DOAC anticoagulant for the foreseeable future) Thoughts on TB4 in this instance?

Mentiined intraoperative dose and mixing with other peptides. Sorta confused. 0.250mcg with intraoperative AND mixing or "also if" mixing? Tb4 with bpc 157....0.250mcgs then or still .750mcg a day?

I have had ulnar and radial nerve issues. What peptide would you recommend for nerve damage? (BPC-157 did nothing for me)

Hi Drew, do you know of a safe source for TB4 in Canada? TIA

Just had metacarpal surgery and ran 10 MG of TB-4 with the 1.5mg/day protocol. Do you usually have patients cycle off now or run 750 mcg till they’re healed?

Which peptide is good for stiffness and general arthritis conditions? I’ve heard thymosin can cause some issues

Hi doc, I’ve watched about 20 of your videos in a row now and man do I wish you were in london😂. There seems to be no way of getting Tb4 in london from a reputable place, what do you think about using TB500 with BPC 157 post PRP or bpc and GH. I’m skeptical about using tb500 as you mentioned that it’s a strong anti inflammatory and I feel that would undo what the PRP is trying to achieve. Love the videos and a reply would be greatly appreciated

I know that all anti-inflammatory medications should be stopped before the stem cell therapy and PRP. For how many days should I NOT take the Thymosins and the BPC 157 before the start of stem cell therapy and PRP?

What effects, if any, would this have on stage 2 avn in the hip of a 43 year old healthy male? Really trying to avoid decompression surgery. Thank you.

Awesome video thanks heaps! I’ve had an injury of the manubriosternal joint from dips for nearly 2 years. I’m finally able to lift again but still very careful. Doctors haven’t been able to fix it at all. MRI showed inflammation at/around the joint. Will tb 500 injections possibly help this? And how long/frequently would it need to be done? Thanks again

For Rheumatoid Arthritis how much TB 4 do you take and for how long?

Hi Drew. What other peptide would you recommend for a meniscal tear (cartilage) aside from BPC 157, TB 4? Thanks in advance Drew

Can you inject tb500 straight into a problematic ligament? I’ve done it with bpc157 and had great success

Can you Mix box-157 and tb-500 together for a single injection? As well as what doses would you go with for both. I have a herniated disc with massive sciatic pain

Can people ever use this long term as a preventative? Is there any problem with say 2x per week .15 ml @ 2000mcg/ml ?

If someone wanted to use BPC 157 (and possibly TB 500) after an achilles tendon surgery, how long after the surgery should one start? Also, PT would obviously help the process. However, PT is usually withheld for a few weeks after this type of surgery. Should one wait to begin PT before beginning a cycle? Thanks in advance.

How much Tb500 to inject? How do I find the correct dosage on an insulin needle? Please doc, using it for a back injury.

what happens if you dose 10mg of tb4 in one go?

Since thymosin b4 is more complicated (43 vs 7 amino acids) does that mean it has potentially more side effects or adverse reactions than the simpler form? And is it more fragile to handle?

Hello Sir, Can you tell me if this is safe to take if the person has diabetes?

Is it possible to take 10mg of TB500 a day for the next 10 days after a surgery so that it can heal real quick or heal quicker than usual? Please do get back to me asap I'd appreciate it many thanks!

Who is a credible manufacturer of this product and BPC 157 and TB 500?

Hey doc, great presentation. Does it matter where the injection site is? One doctor has told me it should be injected to near the injury site, but everywhere I read on the internet says it can be injected just into the stomach fat as it is sytimatic

Ratio for reconstitution?

so were can i get this tb4

How do we get a prescription for Thymosin Beta4? I do have a compounding pharmacy.

If its naturally released at wound sites why would the natural amount not be the ideal amount?

So you would still use Tb500 in bone fractures? I got 2 transverse process fractures and wanted to use Tb500+Bpc157 to speed up healing Kind regards

im trying to find some tb4 because i snap my bicep tendon . but everybody i know only have tb500 .. and bpc 157 . do you think tb500 and bpc 157 will do a good job?

Wish to know a physcian who could prescribe it but since I live in a country where most of them are not interested in health and just in making money on sick ppl I guess there will never be a chance.

Tb 500 has 47 aminos

Appreciate that you answer questions here. I have torn cartilage in my left knee and would like to try this. However, my original injury was from a fall while pregnant 28 yrs ago on my right groin that they still have not figured out - getting an MRI finally. I gave up and used an acupuncturist and chiropractor to get moving. If it is something torn on this area could I use it there as well. I am 72, they say bowel is good although that was the area I had problems with. Xray from chiropractor showed my pelvic bones were not even. Recently I caused something to irritate the area and I am in pain there with certain movements and this made me use my left side (knee) more and irritate it while it was healing from another tumble down wooden steps...so the knee did not heal and got worse. Do you know who could treat me here in Canada? Or will I have to give myself injections? Do not have a regular Dr. (we are short Dr.'s here in areas of Canada) but luckily I am a healthy and active person. So do not have someone to ask about this. Any help is appreciated.

Drew. If you ever do another video. DO NOT DRINK OR EAT RIGHT INTO THE MICROPHONE.

how do we get this guy to stop slurping his tea on the microphone in the middle of a lecture?