I Swear, I could kiss you man. You got me through Immunology as an undergrad and now I'm on my PhD and still watching your videos for guidance. Thank you so much!
Winner of a video, I been tryin to find out about "hypersecretion" for a while now, and I think this has helped. Ever heard of - Yannabarn Vanish Thyroid - (do a search on google ) ? Ive heard some incredible things about it and my m8 got cool success with it.
@@owais6162 In some culture kissing a man on the chick is not gay... Moreover you don't know if he is or not ! Not to mention that being gay is not a shame or what :)
Mr. Hasudungan, I commented a while back in one of your newest videos about how I didn’t like the fact that now you weren’t doing hand drawings. Now, in this 2012 video I see how much effort and quality you have put into your videos. It really touched me to see how you colored that entire big arrow with those thin markers. I haven’t checked out if you have released new videos but regardless of the method, I am grateful for your channel and I really thank you for the time you devote to making these videos.
Hey, Possibly there is some controversy with this, but what I know, and the sources I use state that pendrin is a IODIDE transporter, and therefore Iodide has to be in the colloid for conversion. It states that "On the lumenal side of the apical membrane Iodide is oxidized" Werner & Ingbar's The Thyroid: A Fundamental and Clinical Text.
Can you explain what happens when too much fluoride / fluorine gets involved here? Seems like it'd potentially react over iodide at least some of the time
There are TWO iodine transporter 1. Sodium Iodide Symporter- seen in "basolateral membrane" of follicular cells which helps entry of iodine from circulation into follicular cells 2. Iodide - Chloride exchanger called Pendrin - Seen in "Apical Surface" of thyroid follicular cells helping iodide into colloid Oxidising happens in "Apical Membrane" of thyroid follicular cells Basically what you said is correct Source - Harrison Internal Medicine 20th edition
Very cool, but a few comments. TRH receptor is coupled to a Gq protein in the tyrotroph cell, and TSH receptor is coupled to a Gs protein in the follicular cell membrane. Another detail is that the negative feedback acts directly and indirectly: by directly inhibiting the production of TSH by the tyrotroph and indirectly diminishing the production of TRH receptors on the surface of tyrotroph cells. Last, but not least, when the iodine attaches to de 5,3‘,5‘ carbons or 3,3‘,5‘ carbons, it is called “reverseT3“ (rT3) and has no biologic activity, T3 has only biologic activity if the iodine is in the 3 and 5 carbons (regardless if it is attached to 3‘ or 5‘ carbon). Very useful video, congrats.
your video taught me more than my stupid textbook ever dreamed of! i actually said "oh!" multiple times while watching. i love all your videos and i geek out on your art. please keep up the awesomeness!
Hey Armando, I've been using your videos to study various parts of human physiology for quite some time. Today I find that on my University website, our Endocrinology module has a link to your videos - the link even mentions you by name!
*Don’t expect to hear this from your doctor, but following the right hypothyroidism diet plan is by far the biggest factor in overcoming hypothyroidism. You can do everything else right and be using the best available supplements or medication, but if your diet isn’t right, then you will be forever fighting a battle that you just can’t win*.Learn more here-> plus.google.com/109849515216441135952/posts/Z5tTgFix6w7
Love your videos!!! I watch them to help me prepare for practicals and exams, they're perfect for integrating all the information from my textbook. I just wanted to note that T3&T4 are amino acid derived hormones, not lipid. Thanks!!
Armando, you have been a lifesaver during my first undergrad in Physiology, and now for my second one in Medicine. Thank you for making concepts look so easy and fun. I can literally watch a video of yours once and it sticks :)
I once learned an entire semester of calculus from an amazing tutor. Now, Armando, you are doing this again for me in AandP. Thank you for your diligent studying and hard work so you can pass the knowledge on. So grateful
All your videos are great, they are my first point of call when I have a new subject to learn... Is there any chance you could upload the posters you draw; it would be great to pin them up on my wall... thank you for the videos your passion for teaching is very evident!
Armando thank you for these classes. I was a second year med student when i started to watch your videos and now i am a resident( soon will be consultant) and still watching you. You are a legend!
Amazing! My daughter was born without a Thyroid! No doctor/Endocrinologist has ever tried to go into any real details about her condition. Only that we have to do blood work often and regulate her medication through the TSH Blood work/Lab test but I am learning that there is more to it than just T3 and Synthetic Drugs. I feel overwhelmed but I am trying to learn more about all of this and to give my daughter the best life that we can make for her to feel better. Thank you so much!
He said it is basically a lipid when it reaches the blood stream for transport because thyroxine binds with plasma proteins which makes it lipid soluble and passes thru membrane easily
I am a visual learner and found this video really helpful in putting all the steps together for the thyroid gland. Helped alot for my lecture in pharmacy school for human anatomy and physiology. Thanks.
Writing from Canada I have had a lot about Dr iyaremoses on RU-vid channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Wow, Armando you are brilliant! Thank you so much for this video, you did a wonderful job explaining the process. I honestly feel like your technique of explaining and sketching was easier to understand than some upscale 3D video (which is totally what I was looking for ha-ha). I love the simplistic Sharpie colors, your exquisite hand writing; and love that you've managed to combine science with art - in my world, most science minded individuals can't draw.
I am thanking God for randomly reaching in your channel...no words . it's beyond words...thank you soooo much..just by a single video..I get addicted to your teaching
Deviprasad Boggupalli true... we can only state it as lipophilic hormones which are able to cross the plasma membrane and cause an action within the cell.
+btingang That is true, but it seems like they don't even cross the plasma membrane, but instead require a transporter despite being lipophilic: press.endocrine.org/doi/abs/10.1210/edrv.22.4.0435
Dude , I Am A 5th Year Med Student In Egypt & Ur Vids Help Me Alot Especially In Internal Medicine , Here Are Some Topics That Will Help If U Explaimed ThemnThe Way You Do , Hepatitis , Hepatic Encephalopthy , Portal Hypertension . . . Please Man :D
i am a pakistani student .. having physiology as a subject.. your videos are great.. i was always confused in physiology but ur videos leads me to the right way.. now i understand it very clearly
Writing from Canada I have had a lot about Dr iyaremoses on RU-vid channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
I watched this because of my hypothyroidism that I was diagnosed with 9 years ago, and because I am a Biological Sciences undergrad I thoroughly enjoyed and understood watching this. I now understand my chronic condition better so thanks ^.^
hey sir ( regard as my teacher ) i am a doctor preparing for MRCOG part 1 and now studying basic science with your help. thanks alot for your work. keep going man.
Writing from Canada I have had a lot about Dr iyaremoses on RU-vid channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Excellent explanation on thyroid. Wish I had seen this prior to Radio Active treatment (X2) which destroyed my thyroid. Lifelong user of synthetic T3 and T4.
Writing from Canada I have had a lot about Dr iyaremoses on RU-vid channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
I should just quit school and watch youtube videos, because I learn more when I watch youtube than go to lecture and listen to a professor with a thick accent that just memorizes what she needs to say to us and bascially just speaks at us and not with us. plus youtube is free, no need to pay tuition. this guy is awesome and should be paid for the amount of time he put in, to make this video
At the end of the video, I think it would help if you zoomed out so we can see the entire picture once you finish.. These drawings and diagrams are amazing and SUPER helpful! Obviously this is an old video but that is my only suggestion!
I have my Molecular Endocrinology Final tomorrow, and I must say, this makes the facts super clear. Loved the fact that you went into the molecular basis of it. Thank you very much!
Writing from Canada I have had a lot about Dr iyaremoses on RU-vid channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Thank you crocady! I have been doing so much research and found the answer ~ I changed doctors, drove three hours away and found a wonderful doctor who has since helped me daughter to get her life back, to feel better by changing to Desiccated Thyroid which has T4 and T3 what your body has to have, both! Blessings to you always!
Great video! This was absolutely saturated with the information I needed to understand the thyroid gland thoroughly. I did have to watch it a couple of times because he is a FAST talker! Obviously highly intelligent. Thank you for posting!
Writing from Canada I have had a lot about Dr iyaremoses on RU-vid channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Great job Armando Hasudungan! Without your very well explained and animated video, It was boring for me to read and understand Guyton book. Thanks a million times;)
Hi Ma'm. I was also born without a thyroid and it's quite a difficult thing to get information about it because we are placed under the category of Hypothyroidism. Their a lot of symptoms of hypothyroidism that has no sign on me. I am almost 20 now and my life has been almost completely normal with the exception of the monthly blood test and the correct medication regulations. I am happy to say the tests lessen as you get older. I sincerely hope that your child is doing well. :)
Thanks ever so much for these vids. ... I'm a super visual learner & this format is so much more efficient for me than anything else I've come across. ... and I spent years in special ed classes learning to mediate my learning disabilities, so that's kind of saying something. 😁👍
i am a nursing graduate and i'm reviewing for my board exam...i find this video helpful for my reviews..btw also a visual learner that's why i appreciate this kind of review setting..can you please post more videos of other physiology or something..coz it really helps a lot..
