Urea & Electrolytes (U&Es) interpretation | 7 MINUTE COMPLETE GUIDE 

Thanks Ellen! Very kind of you to say. Out of interest, who is Andrew? 😂

Thanks Rebecca!

You're welcome!

Hi Chad, I beleive individuals with higher muscle mass will produce more creatinine, and theoretically I suppose intense exercise could raise serum creatinine levels through excessive conversion of creatine --> phosphocreatine (which is an energy producing reaction that happens more in the muscles during exercise, with creatinine as the waste product), however I haven't seen this in practice before. This highlights why it's important to compare creatinine levels with previous results, and why AKI is usually diagnosed by comparing increases in creatinine within an individual rather than just a one off measurement. I hope this helps!

@@medicinemadesimple6273 I was looking for any unnormal reason for the muscle to create more creatinine. If muscles are cramping all the time supposedly this might be the case with CKD. If the blood PH becomes to acid which might cause the muscle cramping would the muscle create more creatinine?

@@chada472 I suppose anything that can cause rhabdomyolysis (i.e increased muscle breakdown). A few examples being overexertion, excessive alcohol abuse and severe trauma such as crush injuries.

And in response to the acidosis, I think acidosis can be a complication of severe rhabdomyolysis when it's secondary to lactic acid build up, hope that's helpful!

Sorry but I don't have a pdf version. Thanks for watching!