Every medical school in the world should close and just have students subscribe to this channel. I am an Australian Emergency Medicine advanced trainee preparing for my Fellowship examinations and I don't know where or what I would be without you!!!
I am currently studying for my CCRN test, and this video was very helpful in explaining the mechanism of action for some common medications seen in the test. Thank you and your team for putting this together!
This video is very very good, I'm new to ICU, can you do a video on the medications use for intubation and why they choose them. Analgesic, paralytic, nerve blocking agents. Thank you
Great one Zach. As for AT-II, I’m with you. As a nurse, it would be very hard for me to advocate for such a drug in any critically ill patient. Especially if they are intubated and/or have any potentially worsening pulmonary pathology. Excess ACE-II can lead to micro and macro vascular endothelial dysfunction. This could potentially worsen any underlying SIRS response, contribute to a pro-coagulopathic state, etc. All of which could contribute to the development of ARDS, DIC, worsening vasoplegia, increased vascular permeability, etc. etc. etc. It just seems like an unnecessary risk to take when we have better options.
You and your team are literally hands down the best out there. Thank you for all your hard work and for helping us all to become better medical professionals!
I am researching this now and any comments appreciated. I am 59 female and only known problems is my recent bloodwork shows my RBC steadily climbing and now flagged high and my hemotocrit and hemoglobin has been flagged high for 8 years. Dr is wanting me to go for a sleep study next week something about oxygen🤷♀️. Also I have to get a thyroid ultrasound annually , it is enlarged and nodules that needs monitored and I have 2 doctors fighting over whether to take it out •. I prefer to keep my organs and no prescription meds.
Best video explaining vasopressors ever! I'm an ICU nurse trying to get into CRNA school and this video definitely helps a lot. Thank you for your hard work!
My understanding is that MAP of 65 is for when you don’t know your patient’s baseline. If you do know your pop patient’s baseline then the goal should be +\- 20% of baseline. Is that correct?
not quite what I expected. Of course it’s pharmacology, And for emergent, acute situations, this is what our system of medicine does best. But we’re talking about things like measures to tide person over until a permanent pacemaker can be implanted. Why is there no mention hear things like vitamin K2 implementation? and, of course, maybe that’s just the thing. Maybe this is solely about pharmacology and nothing else. If there’s anything in this world, that seems obvious when it comes to caring for people at this point in life, it makes no sense whatsoever, but there doesn’t seem to be even a mention of the measures that can be implemented into lifestyle to make a big difference. when it comes to pacemakers, I personally know of one patient who while she waited for her call for a pacemaker, she was open to experimenting with vitamin K2, with medical supervision. That was 15 years ago, and she doesn’t have a fib on a regular basis. She may have it happen if something extreme happens, like she misses most of the nights, sleep, and then has something totally freaky happened on the highway. That might happen once or twice a year, and it comes under control very quickly. Certainly these things should be part of the discussion?
This is so awesome from ninja nerd and Prof Zach , my cardiovascular disease exam is on next Friday and this and atrial fibrillation video just dropped right in time for my further understanding and revision 😄
I really enjoyed this lecture and learned so many things that would have taken me days to grasp from books...your style and presentation are both awesome and concise. Thank you
Incredible video guys! I feel like a lot of learning these things is spaced repetition, contextualisation and seeing the same topic presented in different ways. You do such an fantastic job with these drugs, especially the ones that act on multiple systems. The way you repeat the MOA is seriously great teaching, it makes me understand the principles so that by remembering something like, phenylephrine has strong alpha activity and mild beta activity, you can predict it's effect and side effects. Love it
Methylene Blue fixes many things inside the human body. Are the blood pressure increases caused by taking MB cause for alarm? Cellular respiration is improved with MB, so does one offset the other in terms of oxygen delivery? It would seem that MB would overall be a positive for the patient in most cases.
Hey! Big fan! Really love the videos and how you make absurdly complex subjects so simple and easy to understand. Ive got three questions. #1 I get regularly scolded for saying dopamine is dose dependent. As i understand, internists say that dopamine’s dose dependant title was no longer accurate (according to some recent studies). Again, this probably has low impact on a patient that has already exhausted all other options, but why is this particular drug still named as an option if these potential side effects and overall effectivenes are this extremeis? #2. Based strictly on its mechanism on action and physiological response, should Levosimendan be considered as a possible inotrope? 3. In a cardiogenic shock context (purely from an ischemic etiology) , wouldnt chronotropes and vasopressors induce higher myocardial oxygen consumption leading to a higher degree of tissue damage? Thank you!
I can only answer #3, which is - yes. They are known for being bad if you put them in a peripheral IV. Levophed can cause someone to look like they're going through SJS/TEN if you have to push it through a PIV. It will cause massive sloughing of the skin around the PIV site
Please continue giving back to the Universe…The Universe will give it back to you. You have helped so many of us. I am getting ready to transition to a critical care and your lecture is valuable to my growth.
I watched all of your videos when I was taking anatomy courses and then tutoring anatomy. Now I watch your videos to help me be a good nurse in the ICU. Thank you
I don't understand what stimulates or drives one to put silly ink "art"/ graffiti on a God designed body! It reminds me of walls in the black ghettos, marked up with "cool" crap art!