VIDEO: Cholesterol Is Not the Culprit! I drsinatra.com 

Thank you Doc. for a terrific lecture, very enjoyable. I'm 70, had a H. attach and triple by-pass at 56. At that time I went vegan (Korean food) without the meat, been married to a Korean lady 42 years and happy. I've dealt w/ the public for over 50 yrs., and I can see the love and kindness in your eyes, and your voice. I watched two of your vids, both excellent, but liked this one the best. I've been on statins since 56, and you answered so many of my questions. I will forward this on for sure.

This is how plaques form in arteries. Glucose cause infammation and cholesterol is brought to the inflammed part of the artery to repair the damage caused by inflammation. Cholesterol levels is not an issue. Your liver will produce cholesterol if the blood level is low. Recent statistics show that 70 percent of heart attack patients have normal LDL levels. The problem basically is inflammation of endothelium of arteries. Sugar, trans fats, omega-6 cooking oils increase inflammation. Olive oil, and omega-3 fish oils, and magnesium (which is found in cocao) reduce inflammation. Saturated fats increases both HDL and LDL and their effects are at worst neutral. 1

If you review the Mevalonate Pathway studied in undergraduate biochem and in first year medicine, taking clear note of the downstream effects of blocking HMG coenzyme A reductase, you'd have to agree that statins are pernicious. But most doctors without a PhD and independent research don't know what cholesterol is or what it is needed for in the body (I worked at a medical school genetics lab) including: (1) myelination and re-myelination of axons / adrenal steroid hormone production / stabilization of 100 trillion cell membranes and organelle membranes / vitamin D (a hormone) production / a hormone that informs about 960 genes / etc... (2) prenylated proteins which anchor other proteins to membranes like the enzyme complexes of the ECT (3) ubiquinones, ten of them, where the lack of CoQ10 (ubiquinol) results in rhabdomyolysis / where CoQ shuttles high energy electrons from Complex I to Complex III of the ETC / etc., (4) dolichols needed for glycosylation of proteins where glycosylation takes place in endoplasmic reticulum, cisternae in Golgi apparatus and site specific modification (5) sterols, obvious biochemical roles (6) Heme A for oxygen transport If you block all these essential biomolecules, how can use of statins not contradict the Hippocratic Oath of doing no harm?

Hi People,Dr doesnt look overweight and is over 70 of age.Please do not judge if you do not sby personally and again, we do not have to trust in every single word he says, you do not have to buy his book or supplements but use your common sense and do your best.I trust him more than other thousands of " doctors" who are killing my whole family with statins etc.Thank you Dr Sinatra for sharing your knowledge with us

My mother had 350 cholesterol. Doctor had her arteries check, they were pristine clean. She did have a very healthy diet.

I love this guy! I wish he was my husbands doctor.

im prone to high blood pressure, cutting out vegetable oils has made a huge difference. now i only fry food with coconut oil and/or organic butter from pasture grazing cows.

I am currently reading Dr. Malcolm Kendrick's book The Great Cholesterol Con. You have probably heard of him but for those that don't know him he is a doctor from over here in the UK. As you can tell from the title of his book, he is in agreement with Dr. Stephen Sinatra.

Thanks for telling the truth!!! I have eaten a ton of eggs my whole life!!! I'm not fat and I don't have heart problems!!

You sure did make a big difference. Thank you once again. May you be blessed.

'The mantra that saturated fat must be removed to reduce the risk of cardiovascular disease has dominated dietary advice and guidelines for almost four decades. Yet scientific evidence shows that this advice has, paradoxically, increased our cardiovascular risks. Furthermore, the government’s obsession with levels of total cholesterol, which has led to the overmedication of millions of people with statins, has diverted our attention from the more egregious risk factor of atherogenic dyslipidaemia. Saturated fat has been demonised ever since Ancel Keys’s landmark “seven countries” study in 1970. This concluded that a correlation existed between the incidence of coronary heart disease and total cholesterol concentrations, which then correlated with the proportion of energy provided by saturated fat. But correlation is not causation. Nevertheless, we were advised to cut fat intake to 30% of total energy and saturated fat to 10%.”3 The aspect of dietary saturated fat that is believed to have the greatest influence on cardiovascular risk is elevated concentrations of low density lipoprotein (LDL) cholesterol. Yet the reduction in LDL cholesterol from reducing saturated fat intake seems to be specific to large, buoyant (type A) LDL particles, when in fact it is the small, dense (type B) particles (responsive to carbohydrate intake) that are implicated in cardiovascular disease.' www.bmj.com/content/347/bmj.f6340 'The association between saturated fat intake and cardiovascular disease was examined. Results from three reports of leading U.S. and European advisory committees were compared with results as they were presented in the articles referred to. Findings were put into perspective with results not included in these reports. Different lines of evidence were included in the different reports. No overlap whatsoever was found in the articles included. Most results from the scientific literature were lacking for most different lines of evidence in all reports. All three reports included the effect of saturated fat on low-density lipoprotein cholesterol in the evidence linking saturated fat to cardiovascular disease, but the effect on high-density lipoprotein cholesterol was systematically ignored. Both U.S. reports failed to correctly describe the results from the prospective studies. Results and conclusions about saturated fat intake in relation to cardiovascular disease, from leading advisory committees, do not reflect the available scientific literature.' www.ncbi.nlm.nih.gov/pubmed/22208554 'A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD.' www.ncbi.nlm.nih.gov/pmc/articles/PMC2824152/ 'Current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty acids and low consumption of total saturated fats.' annals.org/article.aspx?articleid=1846638 'Indeed, up until 1999, the AHA was still advising Americans to reach for "soft drinks," and in 2001, the group was still recommending snacks of "gum-drops" and "hard candies made primarily with sugar" to avoid fatty foods.' www.wsj.com/articles/SB10001424052702303678404579533760760481486 'Of the Inuit, for instance, Keys wrote, “their bizarre manner of life excites the imagination”, especially that “popular picture of the Eskimo... happily gorging on blubber”, but on “no grounds” was it possible to suggest that the case of the Inuit “contributes anything” to the scientific record. And in response to a prominent Texas A&M University professor who wrote a critique of Keys, he said that the paper “reminds one of the distorting mirrors in the hall of jokes at the county fair”. Rolling over the opposition by sheer force of will was typical of Keys and his acolytes in defending their saturated-fat hypothesis. Keys was “tough and ruthless and would argue any point”, Oliver, a prominent opponent, said. Since Keys’s allies controlled so many top government health posts, critics were denied research grants and key posts on expert panels. As retribution for defending the healthiness of eggs, despite their cholesterol content, Oliver was publicly branded by two of Keys’s main allies as a “notorious type” and a “scoundrel” because “he opposed us on everything”.' www.independent.co.uk/life-style/health-and-families/features/the-science-of-saturated-fat-a-big-fat-surprise-about-nutrition-9692121.html 'The assumption that a low-fat diet reduces the ‘bad’ cholesterol (ie, LDL) is an imprecise notion. While total LDL may be lowered with a reduced intake of dietary fat, if replaced with carbohydrate, this may increase sdLDL particles (ie, pattern B),which are more atherogenic than large buoyant LDL particles (ie, pattern A). Additionally, data indicate that a high saturated fat intake lowers sdLDL particles and raises large buoyant LDL particles. Thus, replacing carbohydrate with fat may improve the LDL particle size distribution (eg, pattern B shifted to pattern A). Lastly, if fat is replaced with carbohydrate, this may worsen the overall lipid profile (decrease in HDL-C, increase in triglycerides and increase in sdLDL particles).' openheart.bmj.com/content/1/1/e000032.full 'The dietary intake of saturated fatty acids (SAFA) is associated with a modest increase in serum total cholesterol, but not with cardiovascular disease (CVD). High CHO [carbohydrate] intakes stimulate hepatic SAFA synthesis and conservation of dietary SAFA. Hepatic de novo lipogenesis from CHO is also stimulated during eucaloric dietary substitution of SAFA by CHO with high glycaemic index in normo-insulinaemic subjects and during hypocaloric high-CHO/low-fat diets in subjects with the metabolic syndrome. The accumulation of SAFA stimulates chronic systemic low-grade inflammation through its mimicking of bacterial lipopolysaccharides and/or the induction of other pro-inflammatory stimuli. The resulting systemic low-grade inflammation promotes insulin resistance, reallocation of energy-rich substrates and atherogenic dyslipidaemia that concertedly give rise to increased CVD risk. We conclude that avoidance of SAFA accumulation by reducing the intake of CHO with high glycaemic index is more effective in the prevention of CVD than reducing SAFA intake per se.' www.ncbi.nlm.nih.gov/pubmed/21978979 'On Monday, SBU, the Swedish Council on Health Technology Assessment, dropped a bombshell. After a two-year long inquiry, reviewing 16,000 studies, the report “Dietary Treatment for Obesity" upends the conventional dietary guidelines for obese or diabetic people. The expert committee consisted of ten physicians, and several of them were skeptics to low-carbohydrate diets at the beginning of the investigation.' healthimpactnews.com/2013/sweden-becomes-first-western-nation-to-reject-low-fat-diet-dogma-in-favor-of-low-carb-high-fat-nutrition/

It sure is working for me! Triglycerides went down by 2/3! And my A1c lowered from Diabetes to pre diabetes...still working on it. As far as I am experiencing, He is 100% right on, except I don't agree with yoga, just my personal beliefs. The medical side, thumbs up!

I'm so blessed to have listened to Dr. Sinatra's webinar just now! I have been taking many of his heart recommendations that my 97yr old dad has taken & shared w/me! Listen!!!!! 👍

I love you, Donna Engelgau Koslow (moderator)!!!

I agree with everything you are saying Dr. Stephen Sinatra. I have been eating a mediterranean diet since I was 16 (before I realized there was such a title for the diet) and I can honestly say it's been the best lifestyle change I made! I lost weight initially and have maintained that same weight all of these years and I will be 34 this month. I had no idea of the heart healthy benefits this diet has!! I originally decided to eat this way to lose weight and I did, but seeing all of the other health benefits associated with eating this way has led me to understand this truly is the way we were designed to eat. Thank you Dr.!!

Sooooo disturbing! My client's doctors are prescribing statins!!! I love your work and Dr. Berg's videos.

I like this guy and his ideas, and I have watched maybe 200 of these in the last six months! Reappraise all the cholesteral lowering drug trials before 2005. Great idea! I like his diet ideas too, the Mediterranean diet combined with the Pan Asian diet.

This guy needs to be my Doctor. Thank you Dr. Sinatra for explaing this to me. My doctor would not spend this much time explaining this to mw. Thank you to NCBI where you can find the facts to back this up.

Thank you so much for your information .............. Great help

My mom was a nurse. She bought into the low fat diet propaganda and was on low fat yo yo diets throughout the 80s and 90s. We lost her to breast cancer in 2001.

Giving evidence for the reasons to eat butter rather than seedoils would be a better approach than saying “who cares”

Thank you indeed Doctor! It was very beneficial. Earlier I really loved the earthing and grounding & I would certainly go back to it.

I was disappointed to find that in this excellent talk Dr Sinatra did not mention L-arginine. In his equally excellent book, ""Reverse Heart Disease Now", Dr Sinatra says, "As we age, we make less nitric oxide. Deficiency permits blood vessels to constrict and lose their flexibility, contributing to vessel stiffness, inflammation and plaque build up, and hypertension. Moreover a vicious cycle develops: increased blood pressure and inflammation impair the ability of the endothelial cells to make nitric oxide. ......To make nitric oxide, the body needs L-arginine, an amino acid......If you take in a lot of L-arginine, you make more nitric oxide and obtain greater protection against the damaging effects of diabetes, smoking, high blood pressure, free radical stress, and many of the problems related to CVD." Please see pages 109 to 113 especially.

I have been diagnosed with FH. Familia Hypercholesterolemia my total cholesterol is 385 an my ldl is 316 my triglycerides are 55 Hdl is 58 an my CReactive protein 5.48 .... I’m 30 have 2 kids an feel good. I have no other problems. I have started eating fruits and veggies an I don’t want to take statins. In my my situation I don’t know what to do at this point. Should I just wait on my heart attack or take the statins? Please help

I'm a 57 female taking 10mg lovastatin and 4 grams Vascepa

You made a difference in my life.... I was put on statin along with aspirin for stent . You mentioned it depletes CoQ10 I will get some today..... thank you

I enjoyed watching this.i have recently lost 101 pounds and my blood pressure got worse I don't understand this my heart they say is fine but I continue to have chest pain.i had stress test and angiogram both come back fine no kidney blockages either.my cholesterol is 180 they say that's really high I am 52 female.help!

Thank you for the webinar looking forward to the email of information,

Hello Sir, Greetings for the day. Sir One quick question if chronic inflammation is the root cause of all problems not higher cholestrol LDL, then why people are afraid of small dense LDL particles, please can you explain Sir what are they are they risky, and how to save your self from it as People says that they are the biggest actor in forming of plaque. Thank You.

Brilliant. Thank you so much.

What if your ratio is sitting at 4 and have higher blood pressure than usually have had. example usually was 120/70 and now can range from 128/84 to 138/84

can sugar damage be reversed

How about without Heart problem

Sugar is not the problem, it's how much we put into our bodies.

So Insulin is an unfriendly hormone and that sugar itself is the problem? If it's true than why do we needed the pancreas in the first place to make insulin? We were born with it for a very important reason to help gets sugar into the cells of the body. Sugar is not the problem, it's too much sugar when our body can't handle too much sugar. That's the real problems, not sugar or insulin.

WIFI radiation and cell phone radiation is near the infrared portion of the electromagnetic spectrum. Unlike nuclear radiation and X-ray radiation used in hospitals it doesn't have enough energy to damage cells. If you're not afraid of campfires or your fireplace, you shouldn't fear your cell phone.

At 20:15, we learn who falls into the tiny fraction of the population that actually CAN benefit from statins - and it ain't many. And not without the addition of at least 200 mg of coenzyme Q10. Note: Sinatra doesn't mention it, but its important to note that people over 30 should use the reduced form of CoQ10 (ubiquinol), not ubiquinone. It is many times more effective in oral form.

At 25:33, Dr. Sinatra explains why doctors mistakenly prescribe statins: fallacious drug trials in the 1990s.

Wonder what he thinks of Dr. Dean Ornish clinical studies showing reversal of coronary artery disease on a plant based diet

Why no subtitels?

What a great doctor! I love him

Dr. Sinatra is really amazing and inspiring!

Shouldn't my Dr be required to know this? I adhere to ALL his suggestions except juicing (fiber is good). I keep getting told I'm going to die early without statins. But all my reference numbers are great except my LDL-P is very high. My carotid artery scan result was bad too... so? I'm not so sure.

At 9:49, we learn why sugar, transfat, and emotional stress are the real culprits.

If not cholesterol, what forms as plaque on arterial walls?

What is grounding?

What about martial arts like Karate (The real variety) and krav maga which is very intense

the most enlightening information about the subject in this crazy world of confusion. Thank you Dr.

Great and informative video.

Hi, I have just come across your information, I wondered as this was in 2013 I wondered if this Dr was answering any questions or not?I have a few questions but I do not want to sit and type all my questions if there is no-one around to help me, it is actually for my mum, who was taking Statins after she had a heart attack and they put 2 stents in, she came off the Statins but has been on drugs for heart and strokes, only to a few weeks ago have 2 mini-strokes.Thank you.

Its funny how this guy says that cholesterol is not a risk factor for heart health but than tells how to lower bad cholesterol and raise good cholesterol. Same information doctors have been saying for years.

what do you think about Nutrim

Good info, Thanks!

missed your videos on RU-vid

How can I reduce VLDL of 120 with LDL of 19?

he is overweight. I don't get health professionals who are overweight like Dr. Weil as well.

医生你好。 你很了不起。 谢谢

What about products with no trans fats, but they're made with hydrogenated oils, aren't those bad?

Mmmmm butter!

why do I smell cigarette smoke and I don't smoke or am I around smokers so is this a health issue, can someone please educate me on this

My cholesterol is high whats the best and fastest way to get it down? Anybody?

dr. sinatra according to your experience, is it harmful to you heart to put your laptop on your chest and start using it for about 2 hours daily before going to sleep?

Dr you mean that I shouldn't use canola oil in cooking ?

What a great guy. Legend.

If what this doctor says is true the Masai Tribe would have arteries a clean as a baby's bottom instead of being riddled with arteriosclerosis by the age of 30. On the other hand those peoples who eat little saturated fat, cholesterol, meat and animal products in general (a high starch diet) have the longest lifespans on the planet and that includes the Japanese and the Blue Zones of the world. If the Asians knocked of the salt they'd live even longer.

How about 81 aspirin is that good to take I'm 39 ....

I would like to see the lab results from this guy and from his followers. He is right about trans fat but wait 10 years and who knows what they will say then.

Amtonio

Habadash.. shhhhhh

Dude looks pretty healthy!! Lol Maybe it's all the extra cholesterol he gets from animals that makes him look so healthy!

Where the hell is vegan gains? he should watch this . But of couse, he is only interested in watching Dr Neal Bernard who is vegan and Dr michael Greger also.

Oh, look! It's the medical equivalent of the Flat Earth Society!

this guy looks like he is reading from a script...put that together with the fact that his website is very very SALESEY, and im sorry but i dont believe a word of what he says. (i stopped watching after just 8 minutes)