Voltage gated Na channels

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This brief video tutorial briefly discusses voltage-gated sodium channels:
0:00. Introduction
0:14. Structure (activation gate and inactivation gate)
1:09. Three conformational states:
- 1:24. 1. Closed
- 2:30. 2. Open
- 3:54. 3. Inactive (refractory period)
6:51. Where are voltage-gated sodium channels found?
7:24. In-a-Nutshell
7:30. Acknowledgements

Опубликовано:

3 авг 2024

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Комментарии : 45

@nurajannat2514 26 дней назад

Amazing 😍 million times better than books and so called teachers

@kenhandyman4841 11 месяцев назад

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@TheNotedAnatomist 11 месяцев назад

Haha, thank you!

@hellomedicine6490 2 года назад

The clearest video covering this topic. Thanks

@ns687 2 года назад

Thank you prof! VGSC is a fundamental component to understand and this video is crystal clear. Will be using it when I help teach Physiology and Pharmacodynamics to students.

@deocarvalho1767 Год назад

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@paulbraunstein2290 Год назад

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@TheNotedAnatomist Год назад

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@seanbedel7694 Год назад

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@darrelllancaster9554 2 года назад

Thank you, Dr.

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@TheNotedAnatomist 2 года назад

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@ranaa2004 2 месяца назад

Genius! Thanks alot

@TheNotedAnatomist 2 месяца назад

You're welcome!

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@KD-um3sv Год назад

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@primeirrational Год назад

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@TheNotedAnatomist Год назад

Working on it!

@shesaidsomething1 8 месяцев назад

This is a great description of the voltage-gated sodium ion channels at the axon hillock and the subsequent propagation of the action potential down the axon. However, at 2:38 you explain the depolarization of the cell from -70mV. That depolarization is a result of the ligand-gated sodium channels opening when the excitatory neurotransmitters bind to it, allowing sodium (Na+) to enter the cell (making it less negative). That is how the cell actually reaches threshold, going from -70mV to -55mV (at which point the voltage-gated sodium channels open). You can find that description here. ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-BbUcWbtVjT4.html I do appreciate your videos and if I am incorrect please correct me. Thank you!

@anamariamitrea6903 9 месяцев назад

Amazing thank you😭🩷

@TheNotedAnatomist 9 месяцев назад

No problem 😊

@slimshady6597 Год назад

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@ilikokherodinashvili2499 2 года назад

Nice

@anonymous-user-2024 Год назад

Thank you for the channel. Do you have any recommendation for an online anatomy bell-ringer question bank resource for clinical (applied) anatomy? For example: clinical stem question with selecting appropriate tagged structures affected in clinical scenario? Thank you.

@KD-um3sv Год назад

🙏

@drewrobinson36 Год назад

Are there leaky channels that re-polarize the cell membrane as well?

@moamel2486 9 месяцев назад

Thank you I have a question is the inactivation gate also voltage dependent or it’s somehow positively charged so that when the potential difference reverses and reach positive 30 inside the cell it will repel the inactivation gate and causes it to close Or all what I said is wrong But if it’s charged then why when the inactivation gate is closed it will not open no matter how strong stimulation is

@TheNotedAnatomist 9 месяцев назад

The Na gate opens, inactivates and turns to the closed state all based upon the voltage of the membrane.