Which Molecule is the Most Cursed? (Cursed Lore)

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#standing desk #setup #flexispot Shop Flexispot standing desk here!
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This is the third installment of the cursed molecules tier list series - don’t forget to drop a comment down below if you like the new 3D format!
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Support the Channel on Patreon - / thatchemist Join the Community Discord! - / discord
_________
Team
Writer/Producer - That Chemist (Joey)
Graphic Designer/Editor/Animator - ReformLabs (David)
Chemistry Assistant - Maurice
Production Assistant - Aldous (Nicholas)
3D Systems Engineer - Robot Chicken
Thumbnail Artists - RinFroggy & David
Ad Co-host - Teresa
_________
Music - A huge thanks to ‪@S3RL‬ for letting us use his music in the video!
"All That I Need - S3RL feat Kayliana & MC Riddle"
Contact S3RL - withkoji.com/@S3RL
The music in the sponsored segment is "Bonfire - An Jone"
_________
Molecules for this tier list: 1,3-bisohosphoglyceric acid, Novec 7700, Alloxan, Asparagusic acid, Beclabuvir, Cycasin, Methylazoxymethanol acetate, Diminazene, Empagliflozin, Epibatidine, Falcarindiol, Feprosidnine, Mesocarb, Timolol, Hipposudoric acid
_________
References
1,3-bisohosphoglyceric acid content.febsjournal.org/cgi/co...
Novec 7700 www.parallax-tech.com/all3m/n...
Alloxan www.orgsyn.org/demo.aspx?prep=...
Asparagusic acid dmd.aspetjournals.org/content...
Beclabuvir www.clinicaltrials.gov/show/N...
Cycasin doi.org/10.1177%2F10406387930...
Methylazoxymethanol acetate doi.org/10.1111%2Fj.1476-5381...
Diminazene doi.org/10.1016%2F0001-706X%2...
Empagliflozin www.drugs.com/monograph/empag...
Epibatidine doi.org/10.1021%2Fnp900727e
Falcarindiol doi.org/10.1016%2F0048-4059%2...
Feprosidnine pubmed.ncbi.nlm.nih.gov/7449977
Mesocarb pubmed.ncbi.nlm.nih.gov/4825943
Timolol www.drugs.com/monograph/timol...
Hipposudoric acid doi.org/10.1351%2Fpac20077904...
If you want a clip of just the outro to loop and watch - • Cursed Molecules Outro... (go listen to S3RL on Spotify or wherever you listen to music! He's one of my favorite artists and I am so stoked that he is letting us use his music on the channel)

Опубликовано:

30 май 2023

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Комментарии : 335

@S3RL Год назад

Hell yeah, I love being part of this!

@rushoffman2364 Год назад

#1 crossover I never thought I would see

@roberttran1114 Год назад

banger

@yeethappymeta Год назад

no fucking way, I never expected this in a million years. nice work!

@adamantris2 Год назад

no way your music is featured one of that chemist's videos. youre probably one of the last people i expected here and im all for it!

@lilyp4369 Год назад

so happy to see one of my favorite musicians ever to get some love in a chemistry channel lmao

@RamiSlicer Год назад

I like when That Chemist said "It's Chemistrin' Time" and Chemistried all over the place

@Thekingofgodofwar Год назад

Who you gonna chemicall

@jackingwads7513 Год назад

Boo get off the stage

@Smelron3317 Год назад

Did you turn chemical into a verb

@Oracle13 Год назад

Drink that sweet ( ( ( c h e m t e a ) ) ) 🧬 ☕

@Jokke13th Год назад

That's one cursed word

@joshuagoodsell9330 Год назад

My non-chemist friends would be embarrassed for me about how excited I was when you said you'd use 3D models of molecules 😂

@panqueque445 Год назад

My little contribution for the compeelation: I don't know why, but I never noticed any asparagus-like smell in my pee. But I remember this one time I was peeing, looked down and saw the bowl was red. I had a mini heart attack thinking I was peeing blood, until I remembered I'd eaten beetroots for lunch.

@frtzkng Год назад

IIRC the asparagus thing also has a genetic component. Some can eat asparagus just fine, while others produce compounds that would violate the chemical weapons convention

@lapisinfernalis9052 Год назад

@@frtzkng Isn't that the same with broccoli? I know someone who turns into a weapon when he eats broccoli, but I am completely fine.

@jailbrekartz Год назад

@@lapisinfernalis9052 Yes, it is! I know I have the genes for both and it absoluteley REEKS. I love asparagus (it is german cuisine after all), but I can't stand the smell afterwards. It's terrible. I have some work stories involving asparagus, involving me almost getting sick from the smell, even though I am pretty resiliant against smells.

@lapisinfernalis9052 Год назад

@@jailbrekartz I am German myself and I never noticed anything after eating asparagus or broccoli. So I may be lucky. But not with my nose. I smell EVERYTHING. You would think that this is great when you are a chemist like me, but it is also a curse. Especially when the fridge you have to take your stuff out reeks of vomit, rotten cabbage, fish and something uncomfortably sweet even when you are standing 2m away from it. And everyone else seems not to smell a thing.....

@jailbrekartz Год назад

@@lapisinfernalis9052 I have a bad nose and don't smell much at all. It's usually the stuff that reeks that I smell the most, but it's kinda a godsend for my work (nurse). We can swap our genes, wenn du willst!

@ShowMe7. Год назад

the 3d models are so intuitive to people like me who arent huge into chemistry but still wanna watch chemistry videos, i love when theyre added into pretty much any chem videos so thank you!

@jeffstaples347 Год назад

The highlighted area reeeeeeeeeeeeeeeeeally helps me.

@That_Chemist Год назад

awesome :D

@GogiRegion 10 месяцев назад

Even as someone into chemistry, some of them surprise me.

@hexagonist23 10 месяцев назад

The skeletal formula are actually easier to read

@gaburieruR 9 месяцев назад

Easier to read, but the 3D models really show how "cursed" the molecules look irl

@AmethystMoon444 Год назад

Whoever you hired as an editor or if you did this yourself...FANTASTIC. SO GOOD. keep it up!!!!!

@That_Chemist Год назад

David - he is incredible

@reformlabs1050 Год назад

Thanks :D I do appreciate the appreciation XD

@elitearbor Год назад

@@reformlabs1050 Keep rocking on, man. You're doing a great job, seriously!

@reformlabs1050 Год назад

@@elitearbor Appreciate it, thanks!

@kitsunefox2023 Год назад

@@reformlabs1050 I appreciate that you appreciate our appreciation.

@dingusdan9983 Год назад

Back in my high school biology class we were talking about genetic traits such as hitchhiker's thumb and attached earlobes. In some groupwork, I started talking to my teacher about some other genetic traits and asparagus pee smell came up. When we got back to the lecture, my teacher brought up asparagus pee and asked the class who can smell it. I proudly raised my hand up high, but as I looked around the classroom, nobody else was raising their hands and were just staring at me.

@revenevan11 Год назад

I really love the highlighting of the parts of the molecules you're talking about! Very helpful for those of us who don't know all the vocab!

@FirstLast-oe2jm Год назад

Oh I actually have a piss chemistry story! So dog piss, according to my vets report, should have ~4 times the nitrogen as human piss. So I tried to refine dog urea into nitric acid. My neighborhood still doesn't know "the month of 'That Smell'" was me. the nitric acid was shitty and barely worked. I do not make nitrogen from piss any more.

@That_Chemist Год назад

Oh no!

@dragonridertechnologies Год назад

I really hope this one gets featured. It's amazingly cursed for such a short story. Hopefully none of your neighbors watch this, or recognize you, though!

@pedrovargas2181 Год назад

This deserves a spot on That Chemist's "Chempilations". 🤣🤣

@TheMightyOmega-NotTheAlpha Год назад

Not an asparagus pee story, but a lab pee story: Lo these many years ago, when I was the most junior chemistry faculty member at my institution, I was assigned to teach a pre-med general chemistry lab section. We had a weekly meeting about that week’s experiment with the program director. When we got up to pH and buffers, we did (and still do) a pretty standard pH meter titration and buffer stuff. And then she says “the urinalysis strips and specimen cups are in the big storage cabinet in the back of the lab.” Well, the last activity in the lab was that the students collected a urine specimen and did a urinalysis using clinical dip sticks and then did some calculations based on their own results. The director had them bring the damned specimen cups back to the lab to do the analysis, and the bathroom was on the other end of the building, so they were walking down this long hallway past the Dean’s Office with cups full of pee. As I got more seniority, I changed it to extra credit and put the urinalysis strips and chart into the bathroom, and when our case of strips ran out, I discontinued it the whole thing. Bonus: I saw some pretty nasty pee over the years. Some guy comes up to me and asks “what does it mean when the urinalysis chart shows ‘erythrocytes high’?” My answer: “you should probably go see an MD sooner rather than later.” His pee was red.

@LucasBitcoinnaisseur Год назад

Thank you for including 3M Novec 7700 in your video :D I noticed and commented on your video about PFAS that this molecule is one of the most cursed molecules ever. Made my day :)

@That_Chemist Год назад

Oh yeah, I remember! See I do read all the comments :P

@science_and_anonymous Год назад

Short but funny story with pee, I remember working a lot with aromatic thiols in the lab, and one of the most notable side effects I noticed, even with the small amount of exposure I got, was that my urine smelled horribly of asparagus. It was pretty consistent, but still took me a long time to finally come to the conclusion to the source of the smell.

@TCOphox Год назад

I've known about 3M Novec in the server/PC cooling space. But I didn't know they were such cursed looking PFAs... It's like a christmas tree but the decor is just flourine atoms.

@Matthew-cx9gj Год назад

Fluornaments

@ToadJimmy Год назад

I love these molecule visuals! the 3d plus highlighting different molecule parts is super cool to see

@dietrootbeer Год назад

I never thought I would have a story worth a chempilation, but here is my asparagus piss story: During covid I moved to live with my aunt and uncle to take online classes while working on their farm. For about three months during this period, I ate asparagus for dinner EVERY SINGLE NIGHT. They were in season and came from a farm nearby so they were fantastic, however, I got so used to having asparagus piss that I stopped being able to smell it while urinating. Eventually, I moved back home and went out to a bar with my friends. This was about two weeks after I last ate asparagus and I went to the bathroom in this bar to pee, when the guy at the urinal next to me turned to me and said, "Damn dude, you got a bad case of asparagus piss." I didn't even know what to tell the guy. How could my pee still smell?! Anyway, I went out to tell my friends and now they still call me asparagus piss guy.

@toyocolla Год назад

The only thing I found cursed about Diminazene was how so closely symmetrical it is.. _IT WAS SO CLOSE!_

@victordonchenko4837 Год назад

It'd likely tautomerize between the two arrangements -- so it is symmetric on some time scale, and its deprotonated form is symmetric!

@toyocolla Год назад

@@victordonchenko4837 Oh, nice!

@27.minhquangvo76 11 месяцев назад

A while ago I posted a somewhat cursed homework assignment on your DIscord. The compound involved in the assignment was similar to that in 10:56, but what's even more cursed is that it involved a reduction of a diyne bonded to two carbinol groups to a tetraene.

@chemdelic Год назад

Absolute insane editing. Videos are getting better and better!

@bluestonecreeper720 Год назад

Now that I've completed chemistry 1, I understand half of what you're saying instead of none!

@That_Chemist Год назад

hooray :) keep up the good work!

@Tony-zi9qg Год назад

i can't believe none of your cursed videos have featured Calicheamicin γ1 yet. it's got so many functional groups that i've never seen anywhere else before it's amazing. Esperamicin too.

@julian4868 Год назад

I just looked those up and good lord I’ve never seen a molecule so massive. that is insane

@milesmccollough5507 Год назад

actually, one of his other "cursed molecule" videos had calicheamicin in it. he said it was, quote, "GILDED in weird functional groups, there's something cursed everywhere you look," naming in particular the carbamate sidechain and the insane hanging trisulfide as well as the weird interrupted glycosidic chain with the aromatic iodine-subsituted ring.

@Tony-zi9qg Год назад

@@milesmccollough5507 really? Can you share the link? Im on mobile with little data 😅

@cellina.starfire Год назад

@@Tony-zi9qg ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-lPVlM_q7LCY.html this is the one!

@That_Chemist Год назад

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-lPVlM_q7LCY.html

@Karupin-and-chill Год назад

Loving the new style and the smooth animations

@_themonocle_ Год назад

Came for the chemistry, stayed for the desk

@workingsmile3836 Год назад

Now we need the opposite. The prettiest 3d molecules

@lonewizardtv7225 Год назад

Love the visuals, I usually leave these on in the background but now they're FULLSCREEN 😎

@That_Chemist Год назад

Very based

@Khemystriy Год назад

Pee story: I once read somewhere that the body isn’t able to break down all citric acid when consumed in an “overdose”, in theory this would make your pee acidic. At an evening after some alcoholic beverages I decided to dissolve 6.0gr of citric acid in water and downed it. The day after I felt horrible with random bursts of pain high up my back which slowly spread to my bladder. Once I finally needed to pee, it was deep dark brown. Don’t be as stupid as me

@jakethomas5016 10 месяцев назад

Bro why? What did you gain?

@jackwastakenx2 9 месяцев назад

@@jakethomas5016 the forbidden knowledge

@DeathMetalDerf Год назад

Wow!! The tier list software has really come a long way! The way you can point out specific bonds and display things in different colors is awesome!

@That_Chemist Год назад

We also are working on a more advanced model with accurate bond lengths and stuff, but that likely won’t be applied until we do a phys chem video

@DeathMetalDerf Год назад

@@That_Chemist I'm very much looking forward to seeing it!🤯

@Blakearmin Год назад

Holy shit! You're up over 100k, now!? I remember when you had less than 10k and I said that I loved coming across great channels before that they blow up, and look at you now! Congratulations, man! This is awesome!

@That_Chemist Год назад

thank you :)!

@Grateful.For.Everything Год назад

The effort that goes into these videos does not go unnoticed, hell of a lot of work editing all this together for us 🙏🏼 we appreciate it!

@That_Chemist Год назад

thank you :)

@mpioman9885 Год назад

Thumbs up for S3RL at the end! But seriously those 3D molecules and the spinning tier list animation at the end are SICK! thanks for the amazing content.

@jerryguebard4518 Год назад

Lol the Hamilton Morris and Nile snippets are hilarious!

@Mnnvint Год назад

One of the fascinating things about That Chemist is that you can hear his smile.

@That_Chemist Год назад

on no *you can tell* 😳

@lexinwonderland5741 Год назад

Okay dude, i have been dead inside lately, and that NileRed clip made me laugh audibly for the first time in probably a day or two. Great fuckin work as always Joey

@Wreck-It-Ramos Год назад

I appreciate your work. Keep like that!!

@Zadrakos 10 месяцев назад

Very late to the party but holy crap. I'm not a chemist at all, a good majority of your videos are gibberish to me, but I'm super interested in it, and I'm picking up things as I continue to watch your videos. I'm someone who does a good chunk of work in Blender and watching the end of the video, showing what you did in Blender honestly surprised me... a ton of work for a relatively small video / channel compared to others who have a similar quality in editing and such. Honestly, awesome work!

@lapisinfernalis9052 Год назад

Cursed molecule here: When I was doing my bachelor thesis in crystallography, I faced something quite cursed, at least for something in crystallography. 1. I thought that my brownish crystal had a tetragonal spacegroup. (Hint: it wasn't) 2. The data was meh, but still manageable. 3. It was heavily disordered. Imagine a Ag-atom, surrounded by 4 Ga (in tetrahedral formation) wich are connected to a Cp+++ ligand (Cp with 3 t-Bu groups at positions 1,2,4), where all the t-Bu groups are twisted differently. And the cherry on the ice: the counterion was a Ga-atom, with a Cp+++ ligand and 3 O3SCF3 groups. ALL WERE DISORDERED in MULTIPLE ways. It took ages and a bit of help from more experienced colleagues, to get to the conclusion that the crystal was a bad boy and it had actually a monoclinic spacegroup which by chance had the needed measurements for a tetragonal group (a=b=/=c, all angles 90°), but not the right symmetry elements. The thing was still horribly disordered. Fun fact: The crystal wasn't even the reaction product I had to analyse. It happened through an accident, because the guy who made it did assure us, that no radicals were involved. You guessed it. There were radicals inside the flask and when I opened it to take out a crytal, the whole thing intantly reacted as I touched it with a spatula.

@gamerfisch5117 Год назад

very good production quality. I love it

@tim-tim-timmy6571 Год назад

I was at university when I made the link between asparagus and my pee smelling funny. I was studying biochemistry. Apparently I am not always the sharpest tool in the shed.

@spanishSpaniard Год назад

As a biochemistry student bisfosfoglycerate isn't remotely the most cursed chemistry biology can make. If you dislike your eyes look up what GTP cyclohydrolase I does. It opens two 5 membered rings, selectively oxidezes one carbon until it leaves in the form of formic acid and then it catalyzes the formation of a new membered ring with an amine and a ketone. Just look up the reaction.

@andrastisza9080 Год назад

This looks amazing!

@frtzkng Год назад

If you're wondering what a _bad therapeutic index_ is: the therapeutic index sets the doses needed for a pharmacological effect in relation to the toxic or lethal dose. Drugs with bad therapeutic index characteristics have the toxic dose threshold very near the pharmacologically active doses, or display a wide variation within individuals, e.g. a pharmaceutical dose for one may be toxic for someone else.

@jsalsman Год назад

Also, that editing / modeling montage! 🎇

@AmberLam. Год назад

Wow the quality just jumped into S tier for this video. Nice improvements and clearly a ton of work went into this. 💪

@That_Chemist Год назад

Thanks Am :)

@kolbasz3584 Год назад

Love the new format, its really easy to understand and intuitive, great editing!

@That_Chemist Год назад

Thank you!

@klikkolee Год назад

I really appreciate the 3d models! There's often a lot about the shape of a molecule which isn't obvious from the 2d drawing

@luminary69revision2 Год назад

I know I'm late but I really love this format the less polished one you were using does have its own charm but this new one is very pleasant to look at I also appreciate all the extra information you stuffed into this one (since I don't know the first thing about any of this lmao)

@jessicaiwanowski8946 Год назад

A little something for the chempeelation. My high school best friend told me that she always ate asparagus when on an ocean fishing trip with her dad. The asparagus pee attracts fish.

@That_Chemist Год назад

@tachalorah Год назад

A TC and Nigel collaboration would be legendary

@That_Chemist Год назад

Your ideas are welcome - I talk with Nigel on discord

@muffinman3052 Год назад

@@That_Chemist gotta be something piss related. it would be funny or something

@danila.5181 Год назад

Thanks for putting all the definitions on screen. I have absolutely no idea what you’re talking about, so it helps

@ShockedCaucasian Год назад

To start with the color switches showing what youre talking about is awesome!

@Lukey_Starzz Год назад

1:21 Well, I guess I will tell you. I love the new design! Good job :)

@That_Chemist Год назад

Thanks!

@ayakas-kh5mk Год назад

wow...... the production value is just..... so goooooood

@That_Chemist Год назад

Thanks!

@jnelson4765 Год назад

Honestly most proteins look cursed to me but I never got beyond polymers in understanding organic chem.

@jsalsman Год назад

Animations of space-filling balls and sticks are beautiful!

@GiBBO5700 11 месяцев назад

My boy cranks S3RL at the end! Love it bro

@nuip7936 Год назад

production value went crazy

@knightoftime8948 Год назад

one of the bathrooms in my high school smelled so much like piss, i could smell the ammonia. as for how i can discern the smell of ammonia from piss, i might've caught a whiff of very very concentrated ammonia gas from leaving it in a jar overnight for an indicator experiment. two fun facts! its hard to use red cabbage as an indicator for oxyclean, as the oxyclean will go clear after a few minutes. leaving red cabbage in ammonia makes it go from green to yellow, which means that when it turns yellow it's probably a good sign to open it in a well-ventilated area. do not smell concentrated ammonia gas, it will burn your nose(you will, however, be able to discern that oh so ungodly smell from just about anything, including bathrooms that smell like piss)

@bigjay875 Год назад

Love the 3D models 👍

@That_Chemist Год назад

Thanks :)

@DJHLX3 Год назад

New design is slick! Nice! 😃

@everythingexplained3226 Год назад

12:40 I can just see it. The researchers looking at the structure. -Yo dat molecule look cursed AF. -You should put it in your eyes.

@MigraineBuddy420 Год назад

Loved watching this channel grow to produce the content that it does, much love from a mechanical engineer who dabbles in chem

@That_Chemist Год назад

Thank you!

@MigraineBuddy420 Год назад

@@That_Chemist ur so cool 😭

@klikkolee Год назад

I noticed that there were several times where a part of the molecule was highlighted, but the molecule wasn't in an orientation that made it very clear which part was highlighted. Often, you moved on to a different part of the molecule before the molecule rotated enough to get a clear view of what you were originally talking about.

@yinbaro Год назад

Ok, two things. The first one is that I absolutely love the editing work you put into it. I can see there was a lot of thought when colouring and decolouring different parts of a molecule while also doing it simultaneously with the 2D drawing. That was S-tier consideration, overall, a really thoughtful editing. I loved this video Second, I was surprised by the comment you made about that natural product with the azoxy group and how you have never encountered that group in you life. I have been fairly and undesirably involved with this FG. Azoxy groups can be encountered during the whole reaction process of the oxidation of an anilin to a nitro group (or viceversa in the case of the reduction). Since this reaction has to pass through two intermediates before reaching the nitro group (aniline -> hydroxilamine -> nitroso -> nitro), if you wanted to selectively stop this reaction at one of the intermediates, perhaps nitroso, you would have to take into account the kinetics of the reaction, since some yet unreacted hydroxilamine can react with the nitroso to form the azoxy group. There are some papers discussing this very issue about the kinetics, my favourite one is a 2022 Angewandte by Qin et al. that describes the conditions to selectively oxidize anilines to nitroso, diazo or azoxy groups by using Zr(OH)4 and modulating the polarity of the solvent used for the reaction. Of course you can also encounter this issue where you get azoxy groups when you just want to fully reduce or oxidize your nitro or aniline groups, respectively. It has happened to me in the past with the hydrogenation of a nitro compound with an N-benzyl group further down the structure, it just would not fully reduce to the aniline group. I don't know if any of this was useful but hey, #TheMoreYouKnow Anyways, I loved this video. I hope we get to see more of these. Keep up with the good work

@That_Chemist Год назад

Yeah I’m familiar with nitroso compounds, but I haven’t seen a diazo-n-oxide before - nitroso compounds still weird me out because of how infrequently they are seen

@Falco. Год назад

I'm happy you got a sponsor!

@pharmboy9484 Год назад

I used to think asparagus pee was a myth. Asparagus was a fairly common vegetable as a child, and one of the few I'd eat regularly, just had to season it right. It wasn't until I was in my early 20s finishing my undergrad that I was given one of those genetic history kits as a birthday present. Apparently there's a genetic component to it, and nobody in my family had that issue, which may explain why none of us had a problem with asparagus.

@That_Chemist Год назад

Interesting

@noyoucantsaythat Год назад

From now on, I will require every single lady of the night I hire the services of to consume a plentiful plate of asparagus before our usual activity of mario kart and disappointment.

@flintishere Год назад

love the hamilton morris photo :)

@morgan0 Год назад

5:30 it would be cool to see a video on common metabolites that end up in urine which have a noticeable smell which aren’t a result of an infection or disease. mine occasionally smells like butter, which i’m guessing is butyric acid, but also rarely like celery seed and anise, which i’m guessing could be anethole but maybe is something else.

@That_Chemist Год назад

Urine has a spectrum, most certainly

@ZackFreedman Год назад

Your videos are the only ones I click on sight. I'm digging the new pizzazz!

@That_Chemist Год назад

Thank you! Your recent 3D printed board game video was really cool - it makes me want to get a 3D printer eventually

@Joman766 Год назад

This channel went the way of the ordinary sausage. Great stuff in the beginning but as soon as production quality became the priority, personality went out the door.

@That_Chemist Год назад

I really like ordinary sausage - I watch all of his videos, and I think he has a lot of personality in there still

@adamgasth Год назад

Cyclohexatriene should definitely be on the list. It’s just like benzene, but messed up

@M.4.R.V. Год назад

I love the Johnny English reference, great to see it :D

@unairodriguez4446 Год назад

I loved the 3D models, what software was used to make them? Nice video

@That_Chemist Год назад

Blender! We also built a plug-in to generate them automatically from chemdraw, but we want to make it polished before making it available to ppl to use

@Ipwnnoobslegitlike Год назад

wow awesome new look and s3rl? you are one mad lad 🎩

@That_Chemist Год назад

Thank you :P

@pedrovargas2181 Год назад

Rotating 3D models, highlighting specific groups in the 3D and 2D models... Damn, this is One. Step. Above. previous material. Congratulations. The final two minutes, even with mute I can barely read the screen.

@sharpswf Год назад

the amount of effort you’re putting into your videos is incredible and i’m here for it. please keep on keepin on and don’t forget about us when you have 200million subs 😩

@simonschemiebaukasten Год назад

absolut elite these Animations 🤌🤌🤌

@That_Chemist Год назад

thanks! David does an amazing job :D

@shamarsh3882 Год назад

I like that they're rotating like fighting game characters or something lol. I'd like for even the 2D ones to rotate now in the tier list

@That_Chemist Год назад

Like paper Mario :)

@janronschke7525 Год назад

Have a nice asparagus story went to the factory toilet and just asked my kolleg wo was just finished, iv the asparagus soup was good and his bewildered"Where do you know that from" had me laughiung my ass off. Apperently not everyone can smell the vile...

@zincler3123 11 месяцев назад

I'm so glad you put novex 7700 in here

@welporajackwelp4899 9 месяцев назад

That chemist asked for a golden shower of comments

@Thekingofgodofwar Год назад

Is Grimace a 3D molecule?

@Saltssaumure Год назад

The outro music fills me with S3RLtonin :)

@jmowreader9555 Год назад

Everyone wants to see a "Things I Won't Work With" collaboration with Derek Lowe.

@kaboom4679 Год назад

Unfortunately , he doesn't really seem to do a lot of these types of stories these days , or , the How Not To Do It ones . They are pure gold and the comments are pure platinum .

@seokminkang935 Год назад

How did you draw 3D model rotating? They look great!

@That_Chemist Год назад

David animated them in Blender

@GerinoMorn Год назад

I always forget that I ate asparagus, and it goes through my body in under 20 minutes. It's always a mild shock in the bathroom xD

@1marcelfilms 9 месяцев назад

Probably said it before but tetraethyllead has a really funny windmill shape

@JappeChristian 9 месяцев назад

After watching this video, I am going to stop calling myself "diabetic" and instead calling myself "Alloxan-immune".

@Ballzinnis 9 месяцев назад

I hope to see a Nile red and that chemist collab soon

@BryanLu0 Год назад

The new format is very cool though I think slotting the chemicals into the list could use some work

@reformlabs1050 Год назад

Hi, David here (guy who did the visuals), could you please elaborate a bit? I'm open to suggestions :)

@BryanLu0 Год назад

@@reformlabs1050 I think it looks very stiff, maybe more easing?

@reformlabs1050 Год назад

@@BryanLu0 Ohhh yeah, I get what you mean.. the interpolation was set to linear so it's a uniform velocity... It didn't slowly build up to speed and decelerate at the end

@penteractgaming Год назад

propellane, sea urchin borane clusters, boron centered nucleophiles, Zn2(C5(CH3)5)2, helicenes, mobius aromatic systems etc. cursed af molecules

@jacobtierney4419 Год назад

Dynemicin is a good shout

@crossg4434 Год назад

I don't have asparagus pee and when I do I have to eat a lot and it's not very strong at all like it used to be for me

@ethanreddekopp7256 9 месяцев назад

I love the 3d molecules

@Banhammer000 Год назад

ah man i need to flexispot.

@mishael1339 Год назад

I love the new design, but I also loved the charm of manually dragging the molecules to their tier and trying to fit them in. Maybe it's possible to do something that keeps the goof of the old format with the slick of the new design? Just a thought.

@boltez6507 Год назад

what I leart early on is tha chemical molecules can't just be predicted,you just have to remember them

@Kualinar Год назад

Pretty sure that the chemical properties of some of those will drastically change if they are folded in another way.

@hydrogenbond7303 Год назад

Mention of murexid reminded me of story with rhodamin B. It was during our organics seminar. Right before the end, we heard a loud bang. As we walked through the hallway a man with completely pink face and coat passed by. At the end of the hallway the lab door was open wide and also pink. As we peeked from distance, the whole lab was pink. Later we found out that the guy had the dye in separating funnel and of course didn't releave the pressure. As he continued shaking, the funnel got so pressurized It just blew and painted the whole lab pink. And other time someone else managed to get water in large can of LiAlH4...

@koukouzee2923 Год назад

Its 3 am and iam glad i didnt go to bed

@pr0hobo Год назад

I love the style tho I just didn't feel that many of these where really all that cursed from a 3d point of view. maybe one or 2 where kinda cursed due to their 3d nature but the rest only got the higher ranks because of what functionally groups they had which isn't very interesting when we're debuting a 3d molecule tier list. now I know you've already done a bunch of cursed 3d structures before like cubane, helicene, propelane, and adamantane but I'm sure there are countless other structures and such that could benefit greatly from the 3d experience and would have made for a better first impression of this style. perhaps a rotaxane or knot molecule or an endofullerene, maybe even a hyperbolic [7]circulene or [8]circulene. Even if you've touched on some of these types before maybe you could still make a video in the future better demonstrating some of their 3d cursed geometry with this new style.

@That_Chemist Год назад

Yeah that’s a fair point