Will This Solve Organ Transplant Rejection Forever?

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Currently we must have an exact match to receive an organ from a donor, especially kidneys, but that may no longer be an issue.
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Read More:
New Procedure Allows Kidney Transplants From Any Donor
www.nytimes.com/2016/03/10/hea...
“In the anguishing wait for a new kidney, tens of thousands of patients on waiting lists may never find a match because their immune systems will reject almost any transplanted organ. Now, in a large national study that experts are calling revolutionary, researchers have found a way to get them the desperately needed procedure.”
Survival Benefit with Kidney Transplants from HLA-Incompatible Live Donors
www.nejm.org/doi/full/10.1056/...
“Recipients of kidney transplants from incompatible live donors had a higher survival rate than either control group at 1 year (95.0%, vs. 94.0% for the waiting-list-or-transplant control group and 89.6% for the waiting-list-only control group)[...]”
Transplant rejection
www.nlm.nih.gov/medlineplus/e...
“When a person receives an organ from someone else during transplant surgery, that person's immune system may recognize that it is foreign. This is because the person's immune system detects that the antigens on the cells of the organ are different or not "matched." Mismatched organs, or organs that are not matched closely enough, can trigger a blood transfusion reaction or transplant rejection.”
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21 мар 2016

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Комментарии : 407

@rhj122 7 лет назад

I had an incompatible Kidney transplant in 2014 from John Hopkins :) still going strong. thanks for brining awareness to transplants.

@EkAks 7 лет назад

Rob *Congratulations. I wish you a very healthy and prosperous life, bro.*

@BBL885 6 лет назад

Rob, wishing you a long healthy life

@spartangod6096 3 года назад

@zoomzooomfatcrack5062 7 лет назад

Hello Every one!! I was born with one kidney.. In Dec 1998 I had a donor from a motorcycle wreck.. Thanks to my organ donor Dec 23. 2016 will be 18 years and going strong. Charles

@biscoito1r 8 лет назад

We should be printing organs by now

@forgefathereli8354 8 лет назад

+biscoito1r its american puritanical leaders in charge of all the money though... why do you think it took us till the 21st century to even start truly using stem cells even though the concept that a human can create another human and thus baby's / mom's with baby fluids have medical value. The damn greeks put this together long ago, like everything else.... To bad greeks suck at the 21st century without the royalty checks from the world copying them.

@mikewhit433 8 лет назад

+biscoito1r You mean cloning

@biscoito1r 8 лет назад

nop, actually printing, there was a TED-Talk about it years ago.

@biscoito1r 8 лет назад

Eli Gutman I wonder if the reason why the geeks suck so much recently has anything to do with drinking lead poisoned wine in ancient times.

@damagecontrol7 8 лет назад

+biscoito1r we should be printing amy's

@themach1ne635 7 лет назад

I'd give my kidney to a loved one without a second thought, but for me to give my kidney to a stranger it would depend on the person and situation. That being said I am a donor upon my demise.

@yunan9610 6 лет назад

The Mach1ne sell them for money then

@codename9824 5 лет назад

If you’re a donor you and your family don’t have a say in who gets the organs.

@LeslieHernandez-hv2jc 4 года назад

You either believe in giving life or you don't.

@ToneyCrimson 8 лет назад

That 1 guy who disliked this video....i wanna know whats going on in its head.

@JacobWilson777 8 лет назад

he doesn't have any kidneys

@AlexG-mk6gb 8 лет назад

+ToneyCrimson Probably some racist who wouldn't want an African kidney.

@Peng_Pong 8 лет назад

Now there's nine

@hayleyhoward7978 8 лет назад

not its 11 people

@Etothe7 8 лет назад

This is just going to let people take advantage, so they can go back to living a disgusting lifestyle and pass it on to their offspring, and bicker about if Coke or Pepsi taste better, and the only people who are disliking it or the people who are not fat

@MykaGhostt 8 лет назад

I've been an organ donor my entire life. I have opted to donate all of my organs, including skin, eyes, etc. so that others can have them when I die. Whatever is left over or can't be used, for whatever reason, is also going to be donated to science :)

@dalalm1821 2 года назад

You are awesome!

@MykaGhostt 2 года назад

@@dalalm1821 thank you! I just don't see the point of holding onto that stuff after I'm dead since I won't be using it. I could possibly help someone else instead, and I like the idea of that

@Gears_Starting 8 лет назад

It is unfortunate and highly inconvenient that people cannot simply be able to accept organs and other body parts from anyone. It would be most convenient if an individual could accept any organ from a member of the same species. This desensitization method sounds like an amazing thing that could open up more people being able to get organs sooner.

@XxAPartofMexX 8 лет назад

+Gabe Lee Really though, the ultimate solution would be lab grown body parts completely made from the cells of the recipient.

@Gears_Starting 8 лет назад

The Vicatorian That sounds like it could be a good idea as well. That would certainly solve the problem for compatibility completely and allow for direct replacement. However, I wonder how much time, as well as resources, would that require to grow organs for specific individuals.

@XxAPartofMexX 8 лет назад

***** As tech improves, not long at all.

@Gears_Starting 8 лет назад

The Vicatorian Hopefully that will one day be the case. For now we can only hope that would be the case as time passes and that method becomes practiced and advanced enough to do so. I wonder how "not long at all" would actually in that method's finished state. For now though, it seems like desensitization is the best bet.

@prodigygod1 8 лет назад

+Gabe Lee then we all turn into agent smith

@dorenecristler6932 8 лет назад

Thank you for the info on new kidney transplant techniques. I have two good friends on dialysis, one with both kidneys removed and the other with only 3% function. Sometimes you may think what you do might be frivolous, but I want you to remember that information can impact lives in a real and positive way. Thank you again.

@phuku177 8 лет назад

I'm on the Lung transplant list because I was born with Alpha 1. This video made my day!!! Thanks DNews!

@eternal8song 6 лет назад

I had a heart and kidney transplant a few years ago and my antibody counts were so high that they did a run of desensitization procedures on me. So far, no rejection.

@channel-gl5mf Год назад

So pls explain desensization process...

@cancer8343 6 лет назад

Amy:"you can live with one but not with none". So thats why I would donate one of my kidneys. And if I die (am braindead) in a hospital eviroment sure take my organs not like they are of any use for me. I dont think there is any ethical problems regarding organ donation anyone disagrees? Ty

@scifijunky1979 8 лет назад

I still believe that bio printing is a better solution than organ transplants!

@vikashKumar-ir6ph 8 лет назад

yup i agree with you why do we have to depend on someone if we can just take our own stem cell churn out a kidney

@Ben0_o 4 года назад

3D printing takes time. A transplant from a donor can go almost straight to surgery once a proper donor is found. When it comes to organ transplants, time is usually the deciding factor. We can't reliably perform either of these surgeries with zero risk, so neither preference is truly right or wrong at the moment.

@Maria-qm9cg 7 лет назад

very well presented and complete short video. Thanks. Great job!!!

@ARMY_for_10_years 8 лет назад

As a dialysis patient for about 17 years now, this is a blessing. It's really hard to find a perfect match. And if I want a kidney patient, I would be more than willing to donate a kidney or even part of my liver to ANYONE. No one should have to suffer on dialysis. It's annoying, can be painful, and makes you weak and can cause even more health problems.

@michaelbanks7157 8 лет назад

+Erica Beumel Bless you Erica. Your generosity of heart is so beautiful. My honey gave me one of her kidneys and in doing so gave me my life back What a gift!

@AmyShiraTeitel 8 лет назад

+Erica Beumel Thanks for sharing!

@d7q0hdjfq39h 8 лет назад

I would donate it for anybody seriously. My mother died due to lack of organ for transplantation.

@kimheilman186 6 лет назад

I am hoping to be a live kidney donor to my husbands co-worker. I go for all my testing on June 18th. Just something I’ve always wanted to do.

@colewilliams6623 3 года назад

I have been on a kidney/pancreas transplant list for 2 years now. So far I have avoided dialysis. But it is getting closer to being something that I have no choice but to do. I really wish that this technology were commonplace. I am FAR more terrified of dialysis than I am the transplant!

@HyenaHouseENT 8 лет назад

Bae changed her hair color... pink never looked so good

@verleptehenk 8 лет назад

Meh

@Lucasmcz17 8 лет назад

+Hyena House Ent. her right eyebrow is much bigger than the left one. lol

@okantureci7221 8 лет назад

+Actinium Oxide rdddxdwsss

@hayleyhoward7978 8 лет назад

yeah.

@scottvelez3154 8 лет назад

+Lucas Cavalcanti Observant.

@tiesabsil8210 8 лет назад

are you kidning me?

@jayjohn4839 7 лет назад

I'm actually going for match testing for a total stranger to see if I can donate him a kidney. I feel completely compelled to do this.

@jonathansteinfilms 5 лет назад

How did the testing go?

@melexdy 8 лет назад

Im enjoying this while watching my 7th glass of whiskey.

@delux2228 8 лет назад

You must be a bit drunk m8, if you are looking at your whisky instead of drinking it

@melexdy 8 лет назад

SinsiliuxS My liver is trying to explode.. I ll never drink again...

@TXrapidracer 7 лет назад

I received a kidney on March 25, 2015. A brother of mine that served with me in the 3rd Ranger Battalion donated one of his kidneys so that I could get moved to the top of the list. All I can say is that there is no way to pay him back other than leading my life the way he asked me to so I am. I have seen a different way where they remove every single cell from an organ except for the connecting cells and then inject cells from the recipient into the organ which will work, plus the recipient doesn't have to take meds.

@BladerINCThe_Hope 6 лет назад

Joe Martinez godamn that’s rough

@samjannaki5482 5 лет назад

@Cheryl You do realize a person can live a healthy life with 75% of A SINLGE KIDNEY, 100% of 1 kidney is more than ideal.

@pollielobster 5 лет назад

My older sister is waiting for a kidney right now. She has been since December of last year. Part of complications with type 1 diabetes, both her kidneys had shut down. She's been on dialysis since, and nobody in our family is a match.

@domfedorowicz5674 8 лет назад

Totally would give someone my kidney

@frozeneternity93 8 лет назад

Interesting. Couldn't antibody filtering treatment help people that have existing autoimmune conditions as well?

@hayleyhoward7978 8 лет назад

yep.

@Melissa0774 8 лет назад

+FrozenEternity I would think it would make autoimmune conditions worse.

@-pyrosef- 8 лет назад

+Hayley Howard nope.

@frozeneternity93 8 лет назад

Melissa0774 How so? It would remove the antibodies attacking the body and this would probably mean less stress on the persons system which would then probably lead to less of an auto immune response.

@Melissa0774 8 лет назад

FrozenEternity I just wonder if maybe the treatment would make the body less likely to attack the donor organ, but more likely to attack the other organs. Maybe cause an autoimmune condition where there was none before.

@SkydivingSquid 8 лет назад

Incredible! The future is bright!

@deh7335 6 лет назад

She has mastered eye makeup. The extended eyelash look is pretty cool. I've personally never seen that before.

@EricRounds 8 лет назад

This is terrific news! I imagine this will also help with new 3d printed organs.

@mohdibrahim3342 6 лет назад

I have donated my one kidney to my wife..on 20/1/2017.starting my kidney rejected doctor had done plasma phrases, Allhumdulliha she is now all right.. May allha grant every one healthy life..

@hafizahafiza9454 3 года назад

How is she now?

@TherapyWallet 8 лет назад

Amy your hair is awesome :D

@l0re811 8 лет назад

Love the new hair amy.

@DavidPowell 8 лет назад

Love the new hair color!

@gabbibowers2004 7 лет назад

I am a kidney transplant recipient, I've had mine for over 10 years now and I just wish there was a way to get me off of these anti rejection pills. I wonder if desensitization could work for post kidney recipients??

@Vibinator 8 лет назад

im living with one kidney :)

@sadafquavi4970 4 года назад

Kyu diye aap kidney,aur kisko diye

@joebrannon 8 лет назад

Can you please do a video on essential oils and if they work or not?

@cheapcodes413 7 лет назад

i have already donated my heart to you

@Jemalacane0 6 лет назад

Brilliant!

@Stryderr 8 лет назад

Can i donate myself to Amy

@nateseyoum4106 8 лет назад

+Jeffrey Zom roasted lol

@tristangruener9571 8 лет назад

I'm pretty sure that desensitization is already a thing... I just went through a transplant at stanford (with a compatible donor, thankfully) and they told me about desensitization in case I didn't have a match.

@qqq1701 8 лет назад

I'm actually on a drug that purposefully breaks my kidneys. I can just see in a few years they get broken too much and now I need new ones. Good thing we've got this trick figured out.

@-pyrosef- 8 лет назад

breaks your kidneys?? Do you mean it just causes they to work less efficiently?

@-pyrosef- 8 лет назад

breaks your kidneys?? Do you mean it just causes they to work less efficiently?

@qqq1701 8 лет назад

Stephen Fabiano The point of the pill is to break their ability to process sugar and return it to the body correctly. Because they cant process the sugar it spills out into the urine. If I recall about 25% of the sugar spills out.

@MsBabieK 5 лет назад

Please tell me we might be able to do this with the liver and other organs soon too.

@richardtaylor3331 8 лет назад

This is great but now I am just curious as to why this happens?

@firstnamelastname148 8 лет назад

I'd happily give away my kidney

@Radi0activet0ast 8 лет назад

I have chronic kidney disease. My kidneys have failed, currently waiting for a transplant.

@sad_depressed_weeb4996 8 лет назад

great job science.

@JOSEPHBURBOSR 2 года назад

Thank you for some hope, got taken off list because no JAB!?

@JessCastillo1998 8 лет назад

My dad has been alive for 12 years after the transplant

@grndragon2443 8 лет назад

Whatever happen to us going the route they showed years ago on the show Nova? The episode was called " Can we live forever", andNeil deGrasse Tyson hosted it.

@MarshTheBacca 8 лет назад

I would be willing to donate to a loved one.

@NeonsStyleHD 8 лет назад

Your *link* to *TestTube Plus* is *_BROKEN!_*

@dianaarmstrong8820 6 лет назад

I will be donating my kidney to my son.

@PtaszekZPtasiegoMleczka 8 лет назад

I'd like to help out a fellow human, but I'm more scared of things cutting into my body than death... I think?

@AndrewHeard1979 8 лет назад

Hey man, that's a bold statement. Kidney donation really isn't as sever as people think. You should check it out on RU-vid 👍

@DeRien8 7 лет назад

wonder if this is at all related to the mechanism for allergy shots for desensitization

@BrokenLioness 8 лет назад

I just have to say, please become an organ donor. There are so many myths out there about being a donor, like the hospital staff will let you die if they know someone on the transplant list. Thats simply absurd. Did yoi know you can save over 180 people who are in need of transplants? I am a kidney transplant patiant of 14 years! Please Donate Life. Think of it as Recycling ;)

@DieAlteistwiederda 6 лет назад

A. T. Universal health care is awesome, if I need a new kidney, I get the surgery without debt.

@pepperman420 5 лет назад

Did you know That only 9% of plastic you throw at the recycling bin actually gets recycled.

@GheyForGames 8 лет назад

this is amazing holy shit!

@xxjoexboixx 8 лет назад

Will the foreign antibodies start attacking the hosts cells?

@socks6574 6 лет назад

Nooope. The foreign antibodies don't have an immune system to tell them to fight the host cells.

@beutlich99 8 лет назад

And Neal Shusterman's "Unwind" is one step closer.

@1989someguy 8 лет назад

Amy, I love your hair

@muffinpup923 8 лет назад

What is mononucleosis?

@SwiftJ3DI 8 лет назад

This could be a bit of a game changer, what about other organs hearts, lobes of liver and the like?

@Galactipod 6 лет назад

1:23 ...so that the antibodies attack the rest of the body and preserve the one organ?

@unofficialkudo4261 8 лет назад

Can anybody Make a video explaining the difference between Cruise Missiles and Ballistic Missiles..?? Please and Thank you :)

@TMP912 6 лет назад

@Judgment Proof someone who donated a kidney is first on the transplant list is something does go bad with the one remaining. I hope that never happens to anyone, especially my donor.

@handicappuccino8491 4 года назад

What Hospital specialize in this treatment because I’m hoping to get Stem cells for cerebral palsy And with this treatment I could potentially get on the umbilical cord blood from any donor in the world

@occonnerwilderness8923 7 лет назад

I'm a donor so I'm fine with it and I try to encourage other to become donors

@dj-up4nc 8 лет назад

Will go to Brussels.

@FracturedPixels 8 лет назад

I do too many drugs and don't eat very healthy. I kinda need both of my kidneys. And my only loved ones are my parents, who would both refuse a kidney transplant from me on the concerns of my wellbeing over their own.

@CorpusOrganic 8 лет назад

I would donate my brain to a stranger. First I would have to make sure it wouldn't go to waste. Second I would have to make sure hey wouldn't want their body back afterwards. Kappa

@furioustoco2824 7 лет назад

But wont the new different antibodies attack the existing organs?

@DennyDormant 8 лет назад

Link to the Test tube + is not working.

@OnyxDavid11 7 лет назад

can desensitization be done after the patient receives the transplanted organ?

@neilbarbu 8 лет назад

I would for anyone

@Melissa0774 8 лет назад

Couldn't introducing new antogens make the person's immune system attack their own organs? I'd be concerned about this procedure causing or exacerbating autoimmune disorders.

@Spaceskate5 8 лет назад

What causes burning poop ?

@emogirlhashervengz 8 лет назад

I asked my friend if a person can live with just one Kidney and she said no but, Amy said "we can live with one"

@RoadWulf 8 лет назад

+emogirlhashervengz transplanted people only get 1 at a time. So yes you can.

@drb9150 8 лет назад

Why don't the transplanted antibodies attack the recipient's existing organs?

@paddymills 7 лет назад

I think the kidney is the most stolen organ.

@Oljon 7 лет назад

wouldn't this make the person more resceptable to disseace? (i know their life might depend on the transplant, i'm simply curious)

@scottb9997 6 лет назад

for a few days yes but id rather increase my chances of getting the flu for a few days over dying of anything caused by kidney or liver malfunction you seen that shit liver malfunction causes poop to form in your eye

@yumri4 8 лет назад

So the same thing as a 3D kidney but to a real humans kidney? I am glad that we are getting advances in both fields and can share between them. A 3D design file for living human organs is the ideal end point but this is a huge step able to go to both the current method and the hopeful future method of it

@esperanza10123 7 лет назад

I don't know if I could donate an organ while still alive 110% after I'm dead for sure!! I have a lot of health issues and I am allergic to some of the ingredients in anesthetics. I could become very very ill from just going under

@ZombieOnCoke 8 лет назад

You would think after 200 or so years, we'd be masters of the medical field. So much is still unknown, and it's still a giant gamble whether a person dies or not after an operation. Why can't things be easier! R.I.P. Humanity.

@sabinahertzum9728 7 лет назад

The testtube link doesn't work :(

@SOLsingoutloud1200 8 лет назад

what about liver though? im currently on the liver transplant list :(

@1800pouned 8 лет назад

This is what I always thought. Basically Just replace the blood in your body with the blood type of the donor or antigens same thing.

@1800pouned 8 лет назад

I also heard cats kidneys are so good they can filter salt out of sea water. What if there was a way to use those?

@RoadWulf 8 лет назад

As someone who has been on dialysis for 10+ years now, I can say I would like if this actually became widely used. I have O+ blood, have anti-bodies in my system from my last rejected kidney and am an even harder match than I was when I was 17 and had my first transplant. But even if this does work, it's still in the experimental stages from what the video seems to be saying and probably isn't really that widespread around the world. I'll have to talk to the University of Iowa about it, but they haven't brought it up to me, so I'd imagine they have not adopted it yet.

@AmyShiraTeitel 8 лет назад

+RoadWulf Thanks for sharing that! Yes, this research is pretty new and I can't say how soon this might be used in a non-experimental setting, but it's a first step!

@KeatrithAmakiir 8 лет назад

Great hair!

@PrestiegeMaster 8 лет назад

Look at the thumb nail upside down what do u see?

@-pyrosef- 8 лет назад

vaginas

@TinchoX 8 лет назад

+Stephen Fabiano Hah, pretty straightforward huh!

@D20Steel 8 лет назад

that could be usefull for getting rid of allergies...

@d.ashgrove1247 5 лет назад

A person who is declared "brain dead" is given a drug to paralyze them for the harvesting(because the body convulses) but no anesthesia (it's considered a waste of drugs). The persons heart rate and blood pressure increase tremendously as the organs are being harvested. If the brain is truly "dead" then the body would not get any pain signals to react the way it does. There is another youtuber "ANON Z"who posted a video about the laws and harvesting procedures. @

@ManintheArmor 8 лет назад

I suppose this can be likened to having your body learn a foreign language or being taken over by an outside military, assuming your body were more like a country.

@nitishkamble5382 6 лет назад

I have a question In this process of desensitization ,when new known antibodies of that transplanted organ are injected in body they do attacks on the organ of that body or not.. ? If they do'nt why bcoz the organ are also the host for that antibodies? pls solve this doubt of meh...

@Hathur 8 лет назад

wouldn't hesitate to give a kidney to close family or dear friend.. to a stranger or even blood relatives who live on the other side of the world that I don't even know beyond their name? Honestly i can't say I would... I wish I had the strength of character to say I would, but I know truthfully I wouldn't.

@latibass 8 лет назад

It's because of people like you that's why hospitals have long waiting lists.

@alanchung2843 8 лет назад

+Dolan I think it's perfectly acceptable for a person to hold onto their body parts in case someone they care about needs one. It's still their body and body parts. I personally don't care who gets my stuff as long as the parts fit and I didn't have any diseases.

@Hathur 8 лет назад

Dolan I'm sorry but so long as I'm alive and kicking my organs are MINE and nobody elses.. I'll give a kidney to a loved one, but hell no to a stranger. When I'm dead anyone can have my organs (I indicated on my license hospitals can take my organs if I'm dead). The question in the video wasn't if you'd give your organs when you're dead, it was if you'd give ONE of your kidneys to a stranger (you only need 1 kidney to live). I answered no I would not give a kidney to a stranger (while I'm alive), but I would to my family or closest friends. If I'm dead however they can take whatever goddamn organs they want, what do I care, I'll be dead... they can dance on my corpse for all i care.

@xprod1gy9x 8 лет назад

There once was a tv show where people would race across the US to get an organ located in another state

@MrKaintar 8 лет назад

What about livers

@ImpaKtZero 8 лет назад

Can't remember where, but I already saw a video about a technique wich removed all the blood and other things from organs and turned them white and then you could insert everything from the recipient and then transplant it with no consequences, again don't remember where but I'm pretty sure that's a better way to do it than this one

@XBellaEstrellaX 6 лет назад

I’m on dialysis and it sucks

@253198253198 8 лет назад

As long as I can have it back later if I need it

@dianaarmstrong8820 6 лет назад

John Adams if you donate a kidney you’re put on the top of the waiting list for a new kidney.

@dakotacry5265 8 лет назад

does desensitization affect a persons ability to fight off diseases since their antibodies are "desensitized"?

@rhj122 7 лет назад

Dakota cry not anymore then a normal transplant

@NevelinStoichev 8 лет назад

great haircut and color change you look nice

@dbljun7 8 лет назад

The Donor's family should receive $ for the organs . Not just the hospital. At least pay for the funeral. That family built and nurtured those organs through the ups and downs.