Advancing Addiction Science... NIDA is the lead federal agency supporting scientific research on drug use and addiction.
NIDA is a federal scientific research institute under the National Institutes of Health, U.S. Department of Health and Human Services. NIDA is the largest supporter of the world's research on drug use and addiction. NIDA-funded scientific research addresses the most fundamental and essential questions about drug use, including tracking emerging drug use trends, understanding how drugs work in the brain and body, developing and testing new drug treatment and prevention approaches, and disseminating findings to the general public, researchers, policymakers, and others.
Yea but doc were I live will not write Methdone on sub and it rotes you teeth out ! Hell can’t even get pain medication at the drugstore! Because of a shortage!!! Why do USA get all of there medicine out of the country?
NICOTINE ACTIVATES the parts of the brain which Scream "GIVE ME MORE DRUGS" no other substance does this, the brain remains soaking up drugs and need for more after the drug is gone physically. Nicotine IS the Gateway drug to all other drugs. Simple Fact. Nicotine leads to drug addiction & Alcohol.
Dopamine isn't rewarding, it's motivating. I've binged on crack, it doesn't actually feel good, quite horrible actually. You just feel compelled to do it, even as it ruins your night and leaves your bank account empty. It is like having a carrot on a stick you can never reach that you endlessly chase until you are exhausted. No release, only endless compulsion with the constant expectation that it'll feel great, you convince yourself, but when you really look at what it does and how it makes you feel objectively, you realize that it's not pleasure, it is suffering, instantly from the first dose!
Dr. Tookes, I enjoyed watching your video discussing harm reduction. I enjoyed listening to the statistic that those who use syringe service programs are five times as likely to seek treatment, and getting them life-saving medication also guides them to recovery. Harm reduction services make a difference and have a powerful impact on the outcome of someone's life.
Hello Dr. Volkow, I enjoyed watching this video, and I am curious to see where the research goes regarding how addiction affects some but not others. I feel they will find that the people who have addictions may have more childhood or adult trauma than those who do not have an addiction. I appreciate the information you presented, and I look forward to more videos! Best, Savannah
Soooo you’re enabling addiction? And mass distributing plastic and metal for free to people that don’t properly dispose of it? And all on my dollar???? You are the ones that have ruined this country. Junkies get arrested they don’t get free hand outs
I have learned there is no such thing as a recovered drug addict. Just turn your back on them and forget the easiest. The moment I did that with my ex the pain stopped I didn't worry about her. I wish you would have made better choices. But she chose to be homeless and prostitute herself and to get drugs living under a bridge in Chicago and Kedzie in Chicago. She's actually beautiful white girl kind of chubby kind of smart fan she actually has a great oral hygiene so she has all her teeth. But she can cannot get help so fuck it I can keep promoting my time on her. People care about yourself over other people because he's heroin addicts they don't care they don't care at all forget the exist
I am realizing just turn your back on them they are beyond help I turn my back on my ex and I feel so much better she lives on the streets now and he's prostituting herself for drugs and I couldn't be happier in my own private life it's all about me not about them
Dopamine does have something to do with us feeling euphoria, but that's more serotonin than dopamine. Serotonin also makes us sleepy. Probably because it takes the piss out of you. Well, dopamine takes it out of you while serotonin knocks it out of you. That's another reason why you feel tired after being very happy for a good bit of time. The neuron of dopamine is also not what gives you massive levels of energy. It gives you some energy, but it's mostly norepinephrine and epinephrine(noradrenaline and adrenaline) that gives you that. That all has to do with the NMDA receptors; N-Methyl D-Aspartate. The neurons that bind to NMDA receptors are norepinephrine, epinephrine, and glutamate. The neuron glutamate is what gives you excitement. Cocaine binds to the D1-Like receptors(D1 and D5) as well as NMDA receptors. Crank(crystal meth) and Desoxyn(methamphetamine hydrochloride) both bind to D2-Like receptors(D2, D3, and D4). Also, Adderall binds to D1 and D2 receptors, but I'm not sure which of the types and/or subtypes of amphetamine in it is responsible for it binding to both D1 and D2. Maybe it's because all of these different amphetamines are working on the CNS. Who knows! Anyways, I hope this helps some of you.
Also, anything that interacts with your serotonin is going to create the possibility of you seeing things or going into psychosis. I think Schizophrenia had more to do with serotonin than dopamine. I personally don't think dopamine has anything to do with causing Schizophrenia... at all. All it is, is that people with Schizophrenia and Schizoeffective Disorder just so happen to have higher levels of dopamine. Maybe that's the brains way of trying to make things not as bad for you as possible. I think anything with "Schizo" in it is caused by having deja vu either too many times and/or it happened for longer lengths of time than the average person. We also know living in the city also has something to do with it, too. Maybe those were the people in the city who had lots of deja vu and lived a life completely opposite of life in the country because the city, in some ways(a lot of ways), is not the natural world. It's not what nature created. A lot of them may have also been really strange people before they developed it. I'm a weird dude, but... I'm not strange. Kind of like what Waylon Jennings sang: "I've always been crazy, but it's kept me from going insane."
Hi mam i got lungs tb on 2010 i used tb medicine for 6 months and cured from tb but tb medicine like isoniazid tablet caused me into depression like psychosis anxiety insomnia i don't go outside like relatives marriages i am not interested in any work suicidal thoughts fear panic going out dont talk to anyone dull and sad face staring at people they laugh at me mood swings i consult psychiatric doctor in 2012 and till now i am using anti psychotic drugs ozapin 5mg how should I completely get over from depression please sir help me can I use pyridoxine right now to cure from psychotic insomnia and anxiety please suggest me to come over from depression
It’s not it’s one of the many progressive ideas ruing American. This all came from Europe and its progressive and new age over their even. Zoom out at the expanse of history and you will see ONE way of handling junkies and it doesn’t involve holding their hands
Its hard to quit. I always control my emotions, im calm af. But i cant resist when my brain tricks me into snorting\smoking again... "Last time", "good reason", "just to relax" and all that kinda bullshit
Nicotine is quite safe done via vapes .....not cigs....and nicotine is some molecule that the body uses in order to make bigger better molecules to produce shit.
Wine is also fine....done in moderation Wine is like the indica of drinks...gets you chilled....beer has hops and hops are like weed...so beer gets you high....pick your choice....and steer away from cafeine....it broke my ribs and ripped my shoulder muscels from my body....via coughing.....most painfull as per my doctor...more painfull than giving birth by a long shot....so no more coffee ...or coffin ...for me
As a Prince in old Germany once said....coffee is illegal ..just drink a pint of beer now and again........and the nosy self perpetuating noises we get from self important women.....down to coffee etc. Fock that!!!!
but you cannot mention caffeine here or anywhere else as Doctors and other medics depend on it big way The drawback of caffeine makes me phisically and mentally sick......it kills on average one in 3 ppl in the world I guess......coffee is made from roasting beans....roasting makes for carcinogenic elements.....so why is coffee still legal It frikkin nearly killed me
I have been an addict and on methadone. I was all set 2 stop.ibwas in a coma 2 years ago. My children have grown up my son talks 2 me when he sees me. Recently my daughter sent me a tx telling me she wants nothing 2 do with me. I have stopped taking Heroin but it seems 2 b other street drugs. Im 50 n my partner died 5 years ago. I c my mum on a Friday. A just put a face on. I sat alone on xmas day. Im cmfined 2 my bedroom. My house is freezing. I can't seem 2 cope. Im never out xcept for the 2 days i go 2 chemist
I don't believe in Harm Reduction. I work in the homeless community if you show love, understanding or compassion using the harm reduction approach, you put your life in danger. Two of my ex coworkers one shot dead the other nearly died ! In nearly 18 years where I work I've not seen harm reduction work not one time !
That sucks for your anecdotal example, but harm reduction is a temporary solution to gain complete abstinence. Some people are in so much pain from not being able to process childhood trauma to the point of addiction-as we say in addiction communities, drugs are pain medicine.
