Dear Sanket sir we are very much thankful to you for preparing informative videos on molecular docking. We wanted to request you to make video on visualisation of the results of swissdock in discovery studio as earliest. Thanks and high regards,
Hello I tried to analyse my PPI network with bingo. But when i opened it in cytoscape, I could not extend it. The start button is below my laptop task bar. I tried to uphold that but couldnot. How can I solve that problem.
What a disappointing video. To begin with, RCSB was never defined. And then, you never explained that from the Structure Summary window, you can click on the Structure link, which allows you to use your mouse to rotate the image and select a region to examine more closely. That will enlarge the image and show you the bonds linking the amino acids. If you hold your cursor above each of the bonds, without clicking, information will appear at the bottom right of the screen indicating what type of bond it is and which amino acids are involved in the bond information. But above all, you never explained just what the PDB is used for. What are biologists doing with all this information every day? Are they designing molecules to be used as structural inhibitors, which might have therapeutic implications? What else are they doing? Explain all these things, if you are claiming that this is a video for beginners. Start by explaining broad concepts and then illustrate those concepts with a bit of detail. That's what good teachers do.
Hello sir...when i took a drug molecule as ligand..i got warning tht exhaustiveness value is low..so i changed it to 16....and then got the result...will that be fine if i change the exhaustiveness value????
Sir can you make a video where a detailed description of network analysis is present. Or if you have already then please mention. It will be helpful for a beginner like me.
Im performing docking on a known active site so i limited the gridbox around the active site only. Some of the conformations i got after docking were outside the grid box. Is that normal?
I have a doubt. I guess The grid box has to be formed around the active site residues by changing the x, y and z axis values so that the interaction can be calculated correctly,
