Another Acylation reaction! This video looks at the Nucleophilic Addition Elimination reaction mechanism of acid anhydride. It will also look into one the most used pharmaceutical drugs in the world. Take a look to find out.
Yes definitely. You can find all the other AQA vids via this playlist ru-vid.com/show-UCPtWS4fCi25YHw5SPGdPz0gplaylists?sort=dd&view=50&shelf_id=2 Hope this helps!
i dont think the h just falls off. Im pretty sure u have to use some sort of base like pyridine or NET3 to take the hydrogen. So how would u protonate the product if there is no free h+ floating around?
Silly question but with a definite reason for asking....if you mix two (acidic) molecules of succinic anhydride with one (basic) molecule of Zinc Oxide, what happens? I know one mole of Zinc Oxide can neutralise two moles of alkyl thio-acid to make ZDDP. Can it perform a similar trick with SA?
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