Terrific lecture-- Clear. Concise. Easy to understand. Easy to recognize and, just as importantly, remember, salient points. And there isn't much information on aquaporins on the internet. Thank you for the great job and valuable resource.
I been studying the NMDAr and how to inhibit the reabsorption of of Glutamate with antagonist inhibitors. Thank you for explaining everything so well, your videos are a blessing.
Dude yeah, you rock!!! What did you study?? I'm majoring in Nanotechnology, and you've been of great help with bio-subjects and even quantum mechanics! (Zeeman effect)
great description. I read somewhere that the aquaporins in diabetics are damaged and dysfunctional in the pancreas and related organs . do you know any research to back that up?
+AK LECTURES (Andrey K) you're miraculous man..you see there is no word that describes you I'm really amazed I'd never seen a teacher who simplifies things in the way you do..well, I speak alot but it's because I'm grateful
So my book says "aquaporins interrupts [the uninterrupted chain of hydrogen-bonded molecules] by forming hydrogen bonds form the side chain NH2 groups." This causes the central H2O to donate hydrogen bonds to neighboring water molecules (wouldn't that make H3O+?) in the hydrogen bonded chain (also thought this was interrupted and gone), and it cannot accept one from them nor orient to sever the 'proton-conducting wire.' There are so many contradictions just reading it over, but I'm guessing that I'm missing the point. Can anyone help out?
what about ions that carry negative charge (ex: chloride) why they don't pass through it? And what about other hydrophilic molecules tgat are not charged (net charge =0)?
Love your video but I would suggest maybe drawing the protein with alpha helices in order to understand how do water molecules go inside the transmembrane protein.
