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Benadryl (Diphenhydramine) for Insomnia and Anxiety 

Rittenhouse Psychiatric Associates
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Dr. Pagnani of Rittenhouse Psychiatric Associates discusses Benadryl (diphenhydramine) and its potential to be utilized for insomnia, anxiety and other medical conditions. He discusses that diphenhydramine is the active ingredient in many over-the-counter sleep aids (like unisom) and it may be preferred to controlled medications like benzodiazepines, as it does not have the same level of abuse potential. With that said, many individuals fail to recognize the possible side effects of using over-the-counter medications like benadry, which include dry mouth, constipation and bowl obstruction, urinary retention, cardiac arrhythmias (like torsades de points and QT prolongation), seizure, renal failure and others. Finally, benadryl DOES have abuse potential (every medication that causes sedation has abuse potential) and it is recommended that taking any medication (even over-the-counter) is under the direction and supervision of a medical professional.
Dr. Pagnani is the founder and medical director of Rittenhouse Psychiatric Associates, an Instructor at The Johns Hopkins Hospital for the Department of Psychiatry, he supervises psychiatric residents at Jefferson Hospital, he serves on the Young Professional Board of Uplift, the Center for Grieving Children and he maintains a private practice of Psychiatry in Philadelphia where he sees patients for one-time psychiatric evaluations and second opinions. He is a licensed physician and surgeon in NJ, PA, NY, MD, DE, FL and CA and can provide consultations to individuals via HIPAA compliant Telehealth visits living in these locations.
Rittenhouse Psychiatric Associates is a private practice of psychiatry consisting of about 25 psychiatrists, psychiatric nurse practitioners and psychotherapists with physical locations in Philadelphia and Paoli, PA and serving all of PA, NJ, NY and FL virtually via HIPAA compliant tele-psychiatry. Individuals seeking not only evaluations but long-term psychiatric care, can contact Rittenhouse Psychiatric Associates directly.
These videos aim to increase awareness and discussion of mental health topics and to encourage struggling individuals to schedule an appointment directly with a mental health provider. Mental health needs to be normalized, and simply speaking about mental health topics openly, is an important first step.
Dr. Pagnani and Rittenhouse Psychiatric Associates are NOT advocating for or against the use of any mentioned psychiatric medications for any specific individual. Additionally, any side effects mentioned are not a complete list of potential side effects or contraindications to taking any mentioned medications, and all risks and benefits of a medication should be discussed with an individual’s provider at an appointment, before starting, stopping or making changes to a medication regimen.
This video is INFORMATIVE ONLY - NOT MEDICAL ADVICE.
If you are researching a specific topic, please view our RU-vid channel, click all videos and use the search function. Please also visit and follow us on instagram and FB: @RittenhousePsych.
www.RittenhousePA.com
www.ChrisPagnaniMD.com

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27 дек 2022

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Комментарии : 96   
@swangirl63
@swangirl63 10 месяцев назад
I have to resort to Dipenhydramine and other antihistamines for sleep because my doctor won't prescribe something made for insomnia. Benzos and ambien and other insomnia medications are out of favor and the prevailing attitude of providers is "tough it out" I agree it isn't good to keep on these OTC pills but laying awake all night isn't a good option.
@adamrobertson2048
@adamrobertson2048 9 месяцев назад
My provider gives me Alprazolam for general anxiety. I usually end up taking a small dose on my hardest nights usually in combination with melatonin or a natural blend of some kind. Maybe try a different provider
@alexandercantu568
@alexandercantu568 3 месяца назад
Im right there with you. Im a veteran and I can't sleep to save my life. Benadryl stopped working. It only takes the edge off my anxiety now. Been up 24 hours and that's on 200 milligrams
@greg9069
@greg9069 3 месяца назад
Hydroxyzine is approved for long term use. It’s much less sedating as an antihistamine tho, me personally, I take Both and 30-60mg of oral morphine because I have a failed back surgery and severe nerve damage which flares up when I lay down… hell on earth when you don’t have a prescriber for something that you know will help you and be safer than “toughing it out” I almost killed myself and took an entire wall out of my parents house when I was denied pain meds for 18 months.. the medical system has been corrupted by the DEA and I’m sure other 3 letter agencies are involved, they want us dead. However, if your doctor doesn’t prescribe you something you ask for, they are not your doctor, keep shopping.
@shinigami7997
@shinigami7997 2 месяца назад
@@adamrobertson2048Alprazolam is literally xanax , its so addictive and is literally an opioid, i cant do that i’ll literally abuse it
@asoncalledvoonch2210
@asoncalledvoonch2210 Месяц назад
​@@greg9069 Cold Truth. I've been saying that for 20 years.and everyone thinks I'm crazy or have an axe to grind against doctors.
@DBronk22
@DBronk22 7 месяцев назад
I used to have Benadryl prescribed for anxiety and because of how relaxing it is i would take it recreationally as means of staying away from alcohol/other drugs. Then i tried weed and found out green is the way to go for 2 reasons: 1. More relaxing 2. Doesn't make you tired
@alixyxv
@alixyxv Месяц назад
I wish I was old enough to just smoke weed
@CindiP-nm6mb
@CindiP-nm6mb 4 месяца назад
I have terrible insomnia, and was taking diphenhydramine on a fairly regular basis for a number of years. Then my endocrinologist told me that it can cause memory loss, if taken for too long. That scared me quite a bit, so I am still searching for insomnia relief with more natural products. It’s very difficult finding something that works.😢
@daniellevictoria4204
@daniellevictoria4204 3 месяца назад
Any luck?
@MrStrocube
@MrStrocube Месяц назад
Cannabis indica in gel caps, works like a charm.
@marisawoods
@marisawoods Год назад
THANK GOD, I've only experienced a deep depression just a few times in my life. Everything was off, and even though I knew I was home, it felt unfamiliar to me, like darkness enveloping me. I didn't want to get up in the morning, and would feel that unfamiliar feeling start as soon as I saw the sun rising. I was so depressed, I wouldn't shower, it felt off. It's very hard to explain. I had the baby blues, and it was similar to that depression. I took Zoloft, and it helped. I went off of it, because the depression was gone. Several years later, I felt that unfamiliar feeling again, and read a story about Vistaril and Diphenhydramine helping depression. I decided to try it, and it worked EXACTLY as the Zoloft had. I was so thankful, because I HATE taking pills, and expensive doctor visits and prescriptions. It was like a miracle for me, truly. I hope someone else is helped by this. God bless!
@RittenhousePsych
@RittenhousePsych Год назад
Thank you so much for sharing your experiences. It's wonderful to hear that you are doing well. It's very important that if anyone is having difficulty with depression they seek medical treatment from a professional. Thank you again, - Dr. Pagnani
@pcl...77
@pcl...77 11 месяцев назад
​@@RittenhousePsych Thnk you. I take benadryl for sleep and during the day I take two for anxiety and your views on benadryl and anxiety were assuring. Paolo
@brianc939
@brianc939 5 месяцев назад
Benadryl is fantastic for anxiety . Daily dose u need to play with but it's perfect
@KodyBeld
@KodyBeld 2 месяца назад
Unbeknownst to me, this works exactly the way you say it does. The first 3 days I wrote down everything that was bothered me, released All the hate inside depression, anxiety, OCD, etc. today is day four and depression is gone! I feel better but just overall an ordinary amount of climate change, storm anxiety, the storms that's been happening around the globe. And finance anxiety. Back in my psychedelic days I never would have pictured that a sensible amount of Benadryl a healthy sleeping dose would be what I needed. Never listen to your crazy psychedelic friends. Always take what's on the bottle and read about side effects toxicity possible genetic predispositions to diseases and seizures that can happen. When a medicine works for one it might kill the other. Just be careful. And the trip amount is the most unpleasant god-awful thing he'll ever experience compared to the sensible doctor approved amount, that is absolutely obliterated my insomnia. Be careful. Make sure your child is either close to 18 or an adolescent.
@sheenabernett4472
@sheenabernett4472 Год назад
Hi, can you discuss the risks of using Dimenhydrinate (gravol) for anxiety disorders ? What are the long term use risks? Thanks!
@RittenhousePsych
@RittenhousePsych Год назад
Thank you for your question! Dimenhydrinate is an anti-nausea medication (Dramamine in the UK and US and Gravol in Canada) which is an anti-histamine. I have not used dimenhydrinate for the treatment of anxiety disorders in any of my patients (and I would certainly recommend that if someone did, it was only under the direct supervision of a medical provider). It is an interesting question though, as vistaril (hydroxyzine) is an anti-histamine that is FDA approved for anxiety and benadryl (diphenhydramine) is often used off label for anxiety. With all of this being said (to answer your question) side effects of anti-histamines (including dimenhydrinate) can include heart arrhythmia, urinary retention, dry eyes, constipation, dry mouth and others.
@ManishKumar-dy7sx
@ManishKumar-dy7sx 9 месяцев назад
Sir does it helmfor REM sleep disorder... My non REM sleep is ok, only REM sleep is disturbed
@CleofeSitchon-vp1ej
@CleofeSitchon-vp1ej 9 месяцев назад
Sir please help me my anxiety or panic attack was long over 2 years please how to do or what medicine can take
@karlreinke9653
@karlreinke9653 16 дней назад
I’ve taken Benadryl for years for sleep. My doctor said it helps and can be used for sleep deprivation.
@williamwells1862
@williamwells1862 10 месяцев назад
Cream and tablets work on Shingles. Passed on by an excellent hospital.
@geraldinekight7887
@geraldinekight7887 2 месяца назад
Great for psoriasis too,helps with itching.
@hopedream637
@hopedream637 4 месяца назад
Sir !! My friend takes diphenhydramine everyday to fall asleep and if he doesn't take it he feels like he can't sleep I know it has become a habit of him Can you please tell me how to stop him from taking this medicine? He tried not taking it for a day but i guess it has become his mindset that he needs to take med to sleep. Please someone let me know how to help him
@Moonflowers11
@Moonflowers11 Год назад
I was taking Diphenhydramine for insomnia for over a decade. I was taking 50 mg at night. I was recently able to stop. The last dose I took was 10 days ago. I think the only reason I was able to stop taking it was because I gave up caffeine first. I cut down by 25% every month because I wanted to be successful and I thought a gradual weaning would be easier and less likely to cause withdrawal symptoms. I am not having anxiety or problems sleeping. I wonder if the caffeine was the major cause of those issues.
@RittenhousePsych
@RittenhousePsych Год назад
Thank you for your comment and watching our videos! Caffeine can be incredibly problematic when it comes to both sleep and anxiety levels. I want to commend you on cutting caffeine out of the picture, and it's wonderful that you were able to stop the benadryl (and after 10 years none-the-less). That's fantastic! - Dr. Pagnani
@mistybailey
@mistybailey 11 месяцев назад
My pharmacist told me I can take benadryl 25mg every night because I had a round with vertigo been taking it 3 months my pharmacist said 25 mg was safe.
@kcfinnegan6160
@kcfinnegan6160 4 месяца назад
I’ve been taking two 50 milillgram diphenhydramine every night for I’d say 5 years now.
@mjgrant1515
@mjgrant1515 4 месяца назад
i’m impressed that you were able to stop taking 50 mgs after such a long time. i’ve been taking 25 mgs for a couple of years & have tried several times to stop but always unsuccessfully. i never use caffeine because i am hypersensitive to it so stopped that many years ago. i really want to get off this stuff but haven’t found a way. if i don’t take it i get 4 or less hours of sleep but if i do take the 25 mgs i get 7 to 8 hrs of good quality sleep (my fitbit tells me how much deep & rem). after a few days of 4 hours of sleep i give up & start taking the nytol again.
@Moonflowers11
@Moonflowers11 4 месяца назад
@@mjgrant1515 I thought I had eliminated all caffeine but recently I found that the decaf tea I was drinking was affecting my sleep. Chocolate also affects my sleep. Do you take Excedrine or other medicine with caffeine?
@shanshan-wj7of
@shanshan-wj7of 4 месяца назад
I‘m took diphenhydramine some time for sleeping. the problem I found is that it works well on first night only. the sencond night not as good as first night. so I have to stop, take a break.
@sugarfree8303
@sugarfree8303 17 дней назад
My doctor used Benedryl to treat my anxiety a few years back. Now I cannot take it at all because it makes my arms and legs twitch
@nunusthirst167
@nunusthirst167 11 месяцев назад
Hello I have extreme flight anxiety & I fly in 3 weeks. Normally I drink (a lot) of hard liquor on the plane but that doesn’t even work anymore. Can you recommend anything?
@RittenhousePsych
@RittenhousePsych 10 месяцев назад
I appreciate your sharing and honestly. I would highly recommend discussing other options with your provider. It may be best to avoid benzodiazepines (like xanax, ativan, valium and klonopin) if you tend to drink alcohol (particularly to excess). There are other options (such as benadryl, vistaril, gabapentin and others). I do not know what the best option is for you, but I'd highly recommend discussing all of this with your provider. I wish you a safe flight! - Dr. Pagnani
@PoetaCallejero755
@PoetaCallejero755 Месяц назад
Benzos
@jackson505
@jackson505 Месяц назад
@@PoetaCallejero755 Benzos are horrible.
@denisekay4292
@denisekay4292 Год назад
I have terrible restless legs, and Diphenhydramine scares me to a panic. If I *ever* take that medication, my legs keep me awake all night long. Its's truly horrible. Horrible.
@ceramikxxx5882
@ceramikxxx5882 Год назад
Perhaps lower the dosage?
@FOB129
@FOB129 Год назад
A quick 2-3 mile run will fix those restless legs . Trust !
@RittenhousePsych
@RittenhousePsych Год назад
Thank you for watching and sharing your experience. Benadryl has a paradoxical effect in about 10 percent of individuals who take it. Meaning, instead of feeling drowsy and less anxious, it causes these individuals to feel more anxious, more awake and restless. I'm sorry to hear that you may have this reaction, and you'll certainly want to discuss this with your medical professionals, if they are considering writing you for a medication that is an anti-histamine in the future. You could also mention this to your local pharmacist, if you are buying medications for allergies or cold symptoms over the counter, and need help deciding what may be the best option. Sincerely, - Dr. Pagnani
@queenicedcoffee4217
@queenicedcoffee4217 2 месяца назад
I'd take that over trying to sleep with a tooth infection in a heartbeat, talk about god awful.
@andrewbrandmusic1971
@andrewbrandmusic1971 Месяц назад
Same. Can’t take Diphenhydramine in any amount. However, I can take doxylamine (unisom) with no issues except for the nasty hangover the next day.
@Rick_Cleland
@Rick_Cleland Год назад
'Ello there, greetings from Northern Ireland. One day I took one 50mg *_Nytol_* tablet that I had bought to help me sleep and I wanted to try it during the day to make sure I wouldn't have a bad reaction to it. Within an hour my decades long anxiety had went away. It was _not_ a placebo effect.
@RittenhousePsych
@RittenhousePsych Год назад
Very interesting, and hello from the US! Nytol (diphenhydramine or benadryl in the US) is an antihistamine that does have anxiolytic properties for many. It is not FDA approved for anxiety, but a very similar medication (chemically) called Vistaril (hydroxyzine) is. The very fact that diphenhydramine and hydroxyzine are so chemically similar, does suggest that benadryl could be helpful for anxiety. With that said, some have a "paradoxical" reaction to these medications (with them increasing wakefulness and anxiety). They also can have significant side effects, so be sure to discuss with your provider. Thanks again for commenting, - Dr. Pagnani
@lawnmowerman4040
@lawnmowerman4040 Год назад
I moved and quit cold turkey theklonopin gabapetin that I taken for almost 20 years, have not slept 3-4 hours a night since last September I have tried ashwaganda, gaba, Tylenol pm, NyQuil, nothing works except the klonopins what else can I take? Help please
@mistybailey
@mistybailey 11 месяцев назад
TAKE BENADRYL OR NYQUILL 💤
@RittenhousePsych
@RittenhousePsych 10 месяцев назад
Thank you for sharing and your comment. If someone takes medications like gabapentin and clonazepam for decades, it may take a lot longer than expected for them to establish a new baseline, and adjust to being off the medications. I typically recommend a slow titration off of those medications, allowing a patient's system to adjust to each incremental decrease, before making another. Sometimes compounding pharmacies can even be utilized, to make small drops. I do not know what the best approach would be for your specific care, but it may be helpful to discuss non-addictive medications for sleep that may be more potent than some of the supplements that you mention as well, but not have the same risk for significant dependence as the klonopin and even gabapentin. I hope that this is helpful, and wish you the best, - Dr. Pagnani
@darryl163
@darryl163 2 месяца назад
A bottle of scotch
@jackrabbit4907
@jackrabbit4907 3 месяца назад
Hello! Is diphenhydramine the same thing as diphenhydramine hydrochloride? thanks.
@viper5559
@viper5559 2 месяца назад
Yes exactly the same
@rjrod1326
@rjrod1326 9 месяцев назад
Benadryl makes me twitch when I'm falling asleep and makes me sleepless at first
@christopher-xi2ey
@christopher-xi2ey 9 месяцев назад
It has made me shaky nervous and bad anxiety attacks
@cammiefleming8822
@cammiefleming8822 9 месяцев назад
Me too
@Oldmanyellsatcloud1985
@Oldmanyellsatcloud1985 7 месяцев назад
Same 😢
@maglunsodmyraflor5880
@maglunsodmyraflor5880 11 месяцев назад
Good day I just want to ask is diphenhydramine can also be used for skin allergies? Thank you for the response
@RittenhousePsych
@RittenhousePsych 10 месяцев назад
Diphenhydramine (Benadryl) can be used for various types of allergies, including skin reactions. I could not know if it was a good or safe option for someone's condition without an evaluation, but it indeed can be used for some, for these conditions. Best, - Dr. Pagnani
@Cokepencilpsd
@Cokepencilpsd 8 месяцев назад
they make benadryl cream/gel you can rub on hives and bug bites
@Dom-pf8wd
@Dom-pf8wd Год назад
Thanks for the video.Curious (maybe another video?) to know your thoughts on taking melatonin short term and long term as I often switch it up between benadryl and melatonin or recently a combination of both.
@RittenhousePsych
@RittenhousePsych Год назад
Thanks for watching and the kind comment! There are different views on long-term use of melatonin (I am rather comfortable with most patients using it short-term at doses from about 0.5 - 5 mg at night, as long as they are not having concerning side effects, and under medical care). Long-term safety however is not clear. When this is the case, I'll often recommend that patients try to have a few nights a week without a sleep aid (or alternating with another aid as appropriate). While I cannot comment about your specific situation without an evaluation (and you'll want to discuss all of this with your providers) it is not uncommon to recommend that someone alternate. I appreciate the idea for a new video down the road as well! - Dr. Pagnani
@humancapybaras1301
@humancapybaras1301 Год назад
How to take it for depression and anxiety morning shift?
@royrice8021
@royrice8021 3 месяца назад
Never worked for me! 😕
@edbrown5956
@edbrown5956 Год назад
Thanks I just heard about someone who was told to take 4 a day for anxiety. I figured there had to be some side effects. Plus I never heard it being used for this. Btw yeah BENZOs are CRAZY. I'd never want to be on them. High potential for addiction and crazy experience if you stop cold turkey. I'd rather take this than BENZOs although I'm guessing it isn't as powerful in effect as BENZOs.
@RittenhousePsych
@RittenhousePsych 10 месяцев назад
Thank you very much for your comment, and I appreciate your perspectives. Best, - Dr. Pagnani
@lindapestridge3073
@lindapestridge3073 11 месяцев назад
Today a well known Doctor on u tube has recommended this for a very fast heartbeat he said it would slow the heartbeat down would you agree.
@RittenhousePsych
@RittenhousePsych 10 месяцев назад
Interesting question. While different individuals may have different reactions to medications, Benadryl (diphenhydramine) can actually cause tachycardia (a faster heartbeat) or palpitations for some individuals. With that said, it can also decrease blood pressure in some, and if it is helpful for anxiety, one could argue that this would decrease their sympathetic ("fight or flight") tone, POSSIBLY resulting in a decreased heart rate. With that said, I have not heard of it being utilized to decrease someone's heart rate specifically. Regardless, it is very important that if someone is going to take this medication (for any purpose) that they discuss with their medical providers. Thank you for your question! - Dr. Pagnani
@jaggass
@jaggass 10 месяцев назад
Whilst im not a doctor i'd advise people to avoid it. I've quit Benadryl because i became addicted to it and made me feel very sick.
@zolomon6933
@zolomon6933 18 дней назад
I bought doxylamine pills. I needed 4-6 per night to fall asleep. About 100-150mg.
@mariavalore6682
@mariavalore6682 6 месяцев назад
Everything has side effects but safer than sleeping pills!
@dblofresh
@dblofresh Месяц назад
Long term use Linked to dementia
@juliethompson8685
@juliethompson8685 17 дней назад
Water has risks.
@gareth3857
@gareth3857 5 месяцев назад
Took them withdrawal wos tribute
@kyleheard8433
@kyleheard8433 Месяц назад
I’ll take the risks if it means I’ll quit showing up at Buckys wearing nothing but my underwear
@Majorpain32677
@Majorpain32677 2 месяца назад
Just don't take morre than two a day
@ryanlowe7315
@ryanlowe7315 2 месяца назад
Hat man
@williamwells1862
@williamwells1862 10 месяцев назад
Somehow benadryl attacks the shingles virus
@lilolmejusayin8671
@lilolmejusayin8671 9 месяцев назад
L-Lysine. Look it up.
@queenicedcoffee4217
@queenicedcoffee4217 2 месяца назад
Helped me finally sleep without god awful ear and jaw aches anytime I laid down thanks to pollen..I finally could sleep without any pain and feel so cozy in bed
@laylahalgharib3150
@laylahalgharib3150 2 месяца назад
Drink herbal tea and save your liver. Meditate. Leave meds alone.
@ajbravens20
@ajbravens20 12 дней назад
Tea is just as bad for your liver isn’t it?
@skatedd2451
@skatedd2451 5 месяцев назад
If I don't take those tablets I don't sleep at all. No sleep for maybe 2 or 3 weeks.. then maybe get a couple of hours and then back to no sleep for 2 or 3 weeks.. no doctor seems to have the answer empty words for an empty audience
@MuneerBaloch
@MuneerBaloch 2 месяца назад
Did you figure out how to quit? I am in the similar situation as you and I just want to STOP!
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