There is so much useless reasearches and so many lies, If I didnt read The 21 Former Doctor Secrets by Rachel Morgan, I would be still believing in tons of nonsense from modern health industry
Unfortunately, the world is populated with science deniers, their followers and people who are ignorant of science. The science deniers are the most dangerous. Be careful who you follow. This video started out well, but half way through, the misinformation started, dangerously so. He just doesn't know the science behind the causes of heart disease and the result is really dangerous recommendations.Yes, high LDL cholesterol over a long period of time is very dangerous. The body makes enough cholesterol for its needs. LDL cholesterol doesn't cause heart disease itself. It doesn't mix with the blood. ApoB lipoproteins are particles that are necessary to transport cholesterol in the blood. When the number of these particles rises to a level above the physiological needs of the body, they can pass through the artery wall in a process known as transcytosis. If some of these particles are retained inside the artery wall they start to get oxidized. This leads to inflammation, an immune system response. The ApoB particles inside the artery wall are like a foreign substance. They don't belong there. The immune system sends macrophages to destroy those particles. Foam cells form leading to the creation of plaque. This is the origin of heart disease. There doesn't even have to be pre-existing inflammation as some YT doctors claim for this process to occur. Anything that damages the lining of the artery will accelerate this process, like smoking, high blood pressure and insulin resistance. Diets high in saturated fats and refined carbs lead to LDL cholesterol synthesis. The higher levels of LDL cholesterol cause the body to produce more ApoB lipoprotein particles to transport it. That is why a diet high in saturated fats is so harmful. Animal fat in the diet should be limited. The best diet is one that emphasizes vegetables, legumes like beans and lentils and I would say omega-3 fish like herring, sardines and wild salmon. I think some low saturated fat dairy like unsweetened yoghurt and kefir is good. Some fruit too, especially low carb berries. Each individual can fine tune their diet according to the condition of their health, but the basic principle is to limit saturated fat. Also, a person with high LDL-C should definitely consider taking a statin. They do prevent heart attacks and strokes and they offer a way to reduce ApoB quickly.
the new way of promoting books is to infiltrate RU-vid comments. she talks about the benefits of intermittent fasting, there are none - aside from calorie control. autophagy happens when you sleep, when you are in a calorie deficit and when you exercise and naturally when you do nothing. In fact fasting itself can help some cancers grow. but as for the rest of it, sleep, eat fibre, etc, we know this already.
What I have come to realise having dealt with many metabolically unhealthy people is this. Attempting to explain and educate on the underlying reasons for their predicament has limited value and tends to lead to selective understanding if not thorough misunderstanding. It’s sad seeing my 75 year old mother and father taken on a ride with the latest weight loss advice after decades of believing in every changing public health advice. Best spend our energy encouraging the simplest health routine of clean water, whole foods, fresh produce, oily fish and lean cuts of meat. A daily prescription of waking up with the sun, walking outdoors for at least 30 minutes, deep breath work for stress and winding down with the moon. When people have mastered that simple lifestyle they have done the best they can and deserve to focus on enjoying connections and experiences that this human experience offers. It’s amazing what falls into place when we stop worrying and start living with a little faith that everything will work out if we stay consistently grounded in basic healthy living I do enjoy the nuts and bolts of our amazing human body. When things go wrong and we end up in hospital it’s surely a good time to catch up on the why of it all but otherwise no need to hyperfixate
Over sixty years of research and all they have is still only hypotheses. The best they can say is that high LDL "associates with," "is linked with" or "correlates with" based on questionable evidence. They cannot definitively say "causes." These hypotheses should have been discarded long ago.
I doubt they could ethically induce high blood pressure or diabetes in people to be able to make causal inferences. New causal modeling approaches might be able to make causal statements using the existing experimental designs, but health science researchers are about 80 years behind where current day statistical modeling is at today.
From the channel, Low Carb Down Under, I've hear of a new theory, Oxidated Linoleic Acid theory of heart disease. One omega 6 fatty acid, linoleic acid, is up to 50% of vegetable oils (butter and meat have about 3-5% linoleic acid). The body cannot burn up linoleic acid for energy, so it collects in cells. It is very easy to oxidize this fatty acid. As it collects in cells, it also collects in the shells of LDL cholesterol particles. It has a high rate of oxidation and damages the LDL in conjunction with high blood sugar. In their lecture, Low Carb Down Under shows a chart of sugar intake, seed oil intake, and death by heart attack over the past century. The rate of heart attack death correlates pretty well with seed oil consumption. Sugar consumption increase earlier and faster than seed oil and heart attack rate
@@offensivearch Even if getting actual causal data is unethical, they are drawing conclusions on "associations" using bad data. Nutritional surveys usually are fairly short questionnaires asking people what they ate over the last month, few months, year or possibly years. People don't remember what they had for breakfast yesterday morning. And people especially in the media cite these studies as strong evidence when that is simply not the case. Nutritional epidemiology could be done so much better than it has been done. Study participants could record what they eat using apps and actual strong associations could be better correlated. The bigger problem actually comes from studies are being done to sell product rather than actually learn something they don't already know.
There are interests running interference. Luckily, meta analysis can expose publication bias, which helps identify the corrupt ones. Like they did with serotonin reuptake inhibitors and amyloid beta links to alzheimers. All based on no evidence, meta analysis shows us.
Exactly! My cardiologist, Dr. Nadir Ali coined that term. He is exposing the ridiculous notion that LDL causes heart disease. Also Dr. Bart Kay is a great resource in RU-vid.
BINGO! Pressure and Turbulence! This was also my conclusion. It took a swimming pool to finally convince me. Holding my hand over a high pressure circulation jet closest to the pump for an extended period of time, my hand started to hurt. Meanwhile the weak jet farthest from the pump didn't hurt my skin at all.
@@arnoldfrackenmeyer8157 Built in obsolescense to make sure we leave room for the next generation? Modern manufacturers of goods realise that well-made, long-lasting goods as per Victorian engineering was a negative rather than a positive.
Interesting. I was watching a debate between Paul saladino and dr Twyman (don’t remember his name) but he was a cardiologist in the field. He said the opposite. Who do i believe lol
There is no difference between the cholesterol in LDL, VLDL, and/or HDL. Cholesterol is not the problem. The difference is in the packaging (proteins). The medical community doesn't have a drug to directly address/treat the APOB, so they promote the fallacy that cholesterol is the problem. Every cell in our body needs cholesterol.
@@nerolowell2320fats are not water soluable, so they need a packaging that will be soluable since the blood is mostly water. APOB is a lipoprotein (part fat part protien) that transports cholesterol from the liver to peripheral tissues. This protien bit “apob” is on the outside and is hydrophilic, while the fat(cholesterol) is on the inside and is hydrophobic. Thus allowing fats to be transported thru blood! Fat or anything that is hydrophobic will not be moved anywhere in the body without these carrier proteins (in 99% of cases)
My total cholesterol is around 250 and my triglycerides are exactly at 50, and my doctor told me I needed to go on a statin.... I walk over 10,000 steps a day, weight train, I am 80% carnivore 20% keto... There's literally nothing else I can do
@@colinfahidi9983 I'm a lean mass hyper-responder doing a very low-carb diet. I also have genetic high cholesterol. Very low triglycerides and one of the lowest CRP scores around. My doc has finally, after 12 years, put me on a very low-dose statin. I hate it, but for the first time, my LDLs are within high-normal range, while my HDLs remain high. I don't have metabolic syndrome, but medical association guidelines have to be observed. Dr Paul Mason (Low Carb Down Under) reports that no clinical studies on statins are longer than 2 years; this is because after that, results are negative, calcium scores get higher, and in fact, it is the statin that kicks off atherosclerosis. Brave New World, eh?
That is one of the best summaries about LDL I have ever heard. Keep up the great content. Important work. My cardiologist, bless his little cotton socks, knows nothing about any of the data you ran through and need a smack in the back of the head to wake up. I am a heart attack survivor twice over and cleaned up my act and got off Statins after a severe reaction with my muscles, ligaments and brain fog. I know you said older subject could have memory loss, and my pharmacist said the same. But I am only 53, so that blood/brain barrier did not stop Statins negatively affecting my brain function. Now that my synapsis is working, I think most on Statins would not know how much they were being affected till they got off it.
My doctor isn’t corrupt. Perhaps you need a new doctor…or better still… take your evidence for corruption to a lawyer and have the doctor charged in a court of law where opinions don’t matter..evidence does…what’s that? No evidence
@@venicebeachsurfer Anyone who understood science from their own research rather than parroting what they have been told to think by authority figures would soon find them thinking a totally different way. Statins do lower LDL but that does not mean it reduces your risk of atherosclerosis. It does mean it risks getting side effects from taking them. "Optimal cholesterol levels don't always translate to perfect heart health, based on a recent study that found half of healthy patients with normal cholesterol levels have dangerous plaque build-up in their arteries." It is also a fact that low cholesterol is dangerous as cholesterol is needed in every cell of your body. There is a theory that 'normal' evolutionary cholesterol levels are much higher than the guidelines and are only set much lower because most people now eat a much higher plant diet than they did prior to 12,000 years ago when the growth of agriculture began.
Probably very high. Mine is 231, which is "horrendous" according to my doctor. He says I won't make it to 50. He also says that my 101/57 BP and my triglycerides(54) are completely irrelevant. I'm hopeful that unless there's some accident, I'll live to 90 like my grandfather whose LDL was always above 200.
@@hjrosas071 I'm sure it was high also. They lived in Belarus where lard, meat, pickled vegetables and vodka was the staple diet. I was told their vaccine was intentional bee stings which they had. Simple, but not easy life.
@@hjrosas071My LDL is 307. I have very low Triglycerides and high HDL. My Doctor must request a LDL test for the 2 LDLS - fluffy good and small invasive particles if she wants my respect. I told her I’m not taking harmful Statins ever. 🎉. Janet
another thing I forgot: Plaques DO NOT begin early in life. What we see in those called "Fatty streaks" are not made of fat (lipid) at all. They are made of white blood cells and NEVER evolutionate into an atherosclerotic plaqe. They have a different origine. We finde those "fatty streaks" even in fetus an newborns, whose cholestero levels are so lo. Their presence have nothing to do with cholesterol or with lipids. Again "The Clot Thickens" by Malcolm Kendrick, will provide you of all the PubMed references. Keep the good work!
Sorry, Dr Alo’s work, a double board certified cardiologist has clearly shown with literally hundreds of rct’s ( gold standard) that ldl is indeed causal in atherogenesis-nuances aside. Ie, easy look: very low or no ldl-no ascvd, period. Larry W Banyash MD
@@user-lu8kj3yk4l I've never heard so much nonsense. Alo is a clown who doesn't know what he's talking about. He even once stated we can live without ApoB. Yet we'd die with no ApoB. Firstly: There's no such thing as RCTs in Humans. Secondly: Neither Cholesterol nor LDL-ApoB are causal of disease. If they were we'd be able to describe the physiological pathway of this alleged causation, yet NO ONE can. "very low or no ldl-no ascvd, period." Whoever said that is also a clown. We'd die with no LDL, and artificially lowering LDL or cholesterol increases risk of heart disease. Whoever Larry W Banyash MD is, he doesn't know what he's talking about either.
@@user-lu8kj3yk4l I've never heard so much nonsense. Alo is a clown who doesn't know what he's talking about. He even once stated we can live without ApoB. Yet we'd die with no ApoB. Firstly: There's no such thing as RCTs in Humans. Secondly: Neither Cholesterol nor LDL-ApoB are causal of disease. If they were we'd be able to describe the physiological pathway of this alleged causation, yet NO ONE can. "very low or no ldl-no ascvd, period." Whoever said that is also a clown. We'd die with no LDL, and artificially lowering LDL or cholesterol increases risk of heart disease. Whoever Larry W Banyash MD is, he doesn't know what he's talking about either.
Most people are low on potassium and low potassium radically increases blood pressure and blood viscosity. Mike, this is really important for people over age 40 regarding boosting potassium levels, as long as you have healthy kidneys
@@zephirinedrouhin3735 the body needs a specific ratio of sodium to potassium it's 1 part sodium 2 parts potassium. 2300 milligrams sodium 4700 milligrams potassium is DAILY recommended. Depending on your activity(if you sweat a lot increase sodium a bit) if your just a small person you will obviously need less. But to be clear you can have a toxic level of anything even potassium. Too much water causes water toxicity. Good luck
Because US foods are packed with added-sugar, we are building up Type B LDL from our childhood years. Even if you lower meat intake, your Type B LDL does not go down if you intake excessive sugar. Minimize added-sugar intake. Avoid Starbucks Frappuccino, drink black coffee, instead, for example.
Here's a ChatGPT summary: - The LDL cumulative exposure hypothesis suggests that minimizing lifetime exposure to LDL cholesterol can reduce the risk of atherosclerosis and related conditions. - LDL cholesterol oxidation and infiltration into vascular endothelial tissue can lead to the formation of atherosclerotic plaque, which can cause strokes, heart attacks, and sudden cardiac death. - Clinical conditions that exacerbate LDL's harmful effects include increased blood pressure, insulin resistance and diabetes, smoking and vaping, obesity, increased blood viscosity, and sedentary lifestyle. - High levels of triglycerides and insulin resistance are indicators of metabolic syndrome, which can worsen the effects of high LDL cholesterol. - Lifestyle changes such as a low-carb diet, regular exercise, and avoiding highly oxidizable polyunsaturated fatty acids can help manage LDL levels and improve overall health. - Statins can reduce LDL cholesterol but may have side effects like insulin resistance, reduced coenzyme Q10 levels, and muscle issues. - There is conflicting evidence about the role of LDL cholesterol in heart disease, with some studies suggesting that higher LDL levels may be associated with increased longevity. - The relationship between LDL cholesterol and heart disease is complex and influenced by various factors, including diet, metabolic health, and genetic predispositions. - Main message: The role of LDL cholesterol in heart disease is nuanced and influenced by multiple factors, including lifestyle and metabolic health, suggesting that a one-size-fits-all approach may not be effective.
Missing the essential ingredient of the issue. Which of the two types of LDL cause this problem. Large buoyant LDL are neutral to Cardio vascular. It is the small dense LDL which cause the atherosclerosis. Avoid all sugar and sources of sugar (carbs) and high LDL is not a problem. More important to watch triglycerides/hdl ratio.
Arthur Agaston now Supports the newer use of CCTA over the CAC - both show arteriosclerosis but CCTA shows how much plaque you're building, how much is fibrous, and how much has already calcified (which he agrees is less harmful). Recommend watching one of the Cleerly webinars in which Agaston discusses different patient cases - he doesn't just look at LDL and he doesn't just throw statins at them.
well said Mike! Nuance conversation, there are several factors involved, not simply just the LDL findings which some might conclude the only reason for heart disease . good vid..
My doctor said high LDL isn’t a big deal unless it passes 200. Currently my LDL is 168 which concerns me but I don’t even have any symptoms from it and he doesn’t take it seriously. He told me to just do keto diet, fast, cut out carbs and sugars and exercise more and told me that I don’t need any med yet since I’m under 50 and my LDL doesn’t pass 200. He said the problem is high Triglycerides which can affect my heart. Currently my Triglycerides is around 40 but only my LDL is somehow high.
LDL is only an indicator. Low dense LDL happens when you are insulin resistant.LMHR is clear high LDL does not cause atherosclerosis if you are healthy and insulin sensitive. Root cause analysis using 5 whys and fish bone analysis will point out to metabolic health
25 years of 25 mg of simvastatin damaged by liver and drove my liver enzymes up. Now with low carb diet my LDL-C is at 112 after taking 5 mg of Rosuvastatin and i200 mg Berberine for 2 months, down from 177. Micro dosing and a supplement has worked for me. I hear that red yeast rice is good too. Too many doctors over prescribe statins.
@DileepB - It is a comfort to read your comment. My doc. put me on 5 mg of Rosuvastatin 3 months ago; he'd tolerated my high LDL/HDL for 12 years (with very low triglycerides/CRP). But now I'm 70, and that "number" means getting a statin, according to medical guidelines. Happy to read that 5 mg is considered a micro dose; got my result yesterday - my LDL is within normal range for the first time ever!
Thank you! I feel like a science experiment. Low triglycerides, high HDL and very high LDL. I’ve had an awful diet for most of the past 50 years, so I’m confused, but you helped me understand some things. I’ve got to get off the seed oils!
I’m in the same boat. I believe we qualify as low mass hyper responders. I’m very physically active. Diet is always a work in progress but even with high LDL I have never felt better. I used to have a constant rotation of health issues. Since going (mostly) low carb , high protein high fat - my doctor visits have dwindled to just yearly checkups.
41m. Started keto back in October 1923 I was 207 pounds I’m 5’6’’. I started carnivore in March. In May, I started to not feel so well and wasn’t sleeping. Got my blood work done the end of May and my cholesterol total was 461. My LBL was 371 and my ferritin level was 470. I never had any metabolic issues prior, starting to be concerned that I have done some serious damage. In May I went back to keto style diet with 30 g of carbs per day and in June I went up to 50 g of carbs per day. I am now I’m at 70 g carbs per day looking to go up to 120 at some point. I am currently focusing on fiber and my blood pressure which had seem to be all over the place, but I think it’s because I was taking too much sodium and not in ketosis. Needless to say I’m a little freaked out. Currently at 174lbs. Getting follow up blood work in Aug to see if the cholesterol comes down. I have been lifting and trying to eat properly for years. Oh and my testosterone was 248. 😑
Hey Mike, thank for your service to us all. I have a question and would love your opinion. I am 47 trim and fit but history of lupus and kidney transplant (and dialysis). Started keto and feel great, all GI issues gone. My Doc is wanting to prescribe statins due to high ldl but also high hdl and low triglycerides. Uncertain from my history if lowering the ldl via meds is the way considering.
I agree with general thesis that keeping LDL low is more favourable for CVD outcomes. However the elephants in the room are the subgroups; 1. patients with low LDL and plaque burden 2. patients with high LDL, poor lifestyles and zero plaque burden 3. healthy, fit people and athletes without FH and high plaque burden.
I am fit and healthy I did drink alcohol and I smoked cannabis but not tobacco. I think the smoking was obviously extremely bad I had borderline high ldl and Trigs. I ended up with significant blockages in my LAD. I ate a healthy diet and was a runner and surfer. Many of my friends smoked a lot drank a lot eat badly and have no heart disease. There’s certainly a genetic factor as my dad had a bypass in his 50s my dad’s mum died in her 50s from heart attack. I now eat a very clean diet I don’t use cannabis I don’t drink alcohol and I take a statin.
@@manyblessings917 yes very positive change, I have low trig, good hdl and low ldl, I have fairly good Apob, could be better but not high at all medium range. I have lowered my BP from 135/85 to 120/75. I managed to reduced my statin by half as the cardiologist was happy with my numbers. I could definitely do better by reducing more sugar and I’m not at all eating a lot at all, and I could reduce carbs. I’m 6’3 I was 13 1/2 stone I’m now 11 1/2 trying not to lose weight is now an issue.
Read "the clot thickens'. Brilliant book explains it all in layman's terms. With the science, that was known years ago but conveniently ignored. Spoiler, it's not LDL!!!
@@truthsayerq7264 No need, here's the goods: pubmed.ncbi.nlm.nih.gov/22959954/ (Lowering Dietary Linoleic Acid) and ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-wICtdUuEYZY.html
You should interview Dr Ford Brewer . He has a channel really good and he is the example . They Him and other docs go into this really well . I would love to have you interview him .thankyou for all you do .
Why is he (or the authors of the study) linking all these known risk factors (absolutely nothing new here) to LDL in order to conclude the risk factor “causes the LDL to cause the damage”. What on earth has high LDL got to do with it. Diabetes, increased blood pressure, smoking are risk factors independent of LDL, for goodness sake. It’s amazing. If you want to understand this, please, please, please read Malcolm Kendrick’s excellent book “The Clot Thickens”. Extremely well documents the science which shows what is really going on. Warning, pharmaceuticals companies don’t like this book!!!
I've had much musculoskeletal undiagnosed pain. I heard of the carnivore diet which is supposed to decrease pain as it lowers inflammation. This material that you talked on regarding cholesterol and LDL, insulin resistance, cardiovascular disease, is exactly what all the carnivore doctors speak of. Compelling stuff!! Thank you
Try a seed oil free diet for 3 months (the Hateful Eight, Dark Calories) These suckers are very inflammatory and penetrate the endothelium, initiating atherogenesis. Cholesterol works as natures band-aid to start repair. They are associative but not causitive.
Rhabdomyolysis is a very real, very serious outcome from statin use. My husband developed it after long-term statin use. I found him unconscious one day out of the blue. He spent five days in critical care, and was diagnosed with Rhabdomyolysis related to Crestor, and diabetes. He has been able to reverse the diabetes through exercise and diet, but the Rhabdomyolysis muscle deterioration continues. He is in increasing pain and discomfort after six years off statins.
HELP WANTED- I'm not very educated in lipid levels. I changed my diet 2 years ago to ketovore and have totally dropped sugar. I just got my blood work back and was flagged with High cholesterol and high HDL. my blood work showed the following, Triglycerides-48, T-Cholesterol-266, HDL-137, LDL-119, VLDL-10. Is this something to worry about?
I certainly don't think so. That HDL is off the charts high and I've never heard someone say that's bad. Your tris are VERY low. Your T/HDL is amazingly low. As the video pointed out, LDL on its own isn't the complete story. How's the blood pressure and BG. Hopefully you don't smoke and you get plenty of exercise.
This is excellent bloodwork. HDL is often called as teh good cholestrol, the higher the better. The most important factor is that tryglicerides should be low and you are right there!
5. Conclusions In conclusion, our work demonstrates that SRP can attenuate the elevated inflammatory biomarkers (MCP-1, IL-2, IL-4, IL-6, and TNF-α), the production of MDA, ROS intensity, CATx, and GSH impact in the setting of LPS-induced vascular inflammation. SRP inhibits inflammation and oxidative stress through the endothelium MCP-1. We concluded that SRP has the ability to modulate vascular inflammation. Further studies will be required to explore the detailed mechanisms of the cardio-protective effects produced by SRP. These results suggest that serratiopeptidase may be a therapeutic agent for vascular inflammation in cardiovascular diseases.
I'm 62, my LDL is 250ish.. Cholesterol 265. HDL/Triglycerides ratio is .68. MY Doctor advised Statins poison. I laughed and said HDL is 72, , Triglycerides 58. . Im 75% Carnivore. . No Bad carbs hardly. Hardly any veggies thanks to roundup. I power walk 2-3 miles everyday.I'll pass on statins Doc.
Hi Mike I enjoy your podcasts and wanted to ask you something about Creatine. I notice your electrolytes gas Creatine in it. I’m 68 yrs of age female who has quite fragmented sleep. Previously when I was taking Creatine I found over time that my sleep hunger reduced to almost zero. Have you heard of this and do you have any advice as I would like at avail myself to the positive aspects of Creatine. 🙏
I'm not a medical student or anything like that, but what I have learnt is the body needs cholesterol andd there are 2 types HDL (I think?) and LDL. HDL is the fat that providde energy and LDL are the repairs (if there ius a leak in veins from smoling, pesticides in food, polution etc. then LDL's come a long and fix to stop blood leakage into tissues)., hence to buil up of LDL in the veins as people keep abusing their bodies and it's a big money maker for pharmacutical companies to blame Fat. when every cell needs energy e.g. Protein 80% / Fat 20% with good fat being higher in producing energy so the brain loves fat as use more energy.
Thank you for this information! I have elevated (small particle) LDL but my LDL/HDL ratio is great, fasting insulin is good and APO B is 80. I have low BP, don't smoke, not overweight and eat well. Am I correct in saying LDL isn't thought to be a concern unless it is oxidized so keeping inflammation low is key. Am I overly simplifying?
There was a reduction in DEATHS from heart attacks not a reduction in the number of myocardial infarction. This mortality reduction was related to the advancement and increased access to cardiac catheterization. It was most significantly affected by the invention of drug alluding stents. It was NOT the conversion of consuming industrial seed oils.
Hello Mike, great background for your videos, I like it a lot. One concept: LDL particles DO NOT get "trapped" in the artery wall and DO NOT CAUSE atherosclesosis. The only LDL that we find in the plaques is de LDL corresponding to Lipoprotein (a), whose role in heart disease works by its thrombogenic role. It inhibits the conversion of plasminogen to plasmin and thus, it blocks fibrinolysis. It is a thrombogenic proccess. If you read "THE CLOT THICKENS", written by Dr. Malcolm Kendrick you will see the real cause of atherosclesotic plaques. It was never LDL cholesterol. Thanks for your work, I like it a lot! Jorge García-Dihinx MD/PhD Division of Pediatrics. Children Obesity Out Patient Clinic. Hospital San Jorge. Huesca. Spain
"Remarkably, one-quarter of the centenarians had high Lp(a) serum levels even though they never suffered from atherosclerosis-related diseases." 1998 G. Baggio.
I don't think these studies taken to a fact genetic predisposition to high cholesterol I don't even eat really unhealthy and I've tried all these natural products and nothing works to lower my cholesterol it's inherited in my family and I refuse to take statins I think sometimes it may just be uncurable have to understand how frustrated someone will get when they're trying everything and nothing's working
Try the Dean Ornish diet. Your diet is probably too unhealthy for your Family history. Or microdose the smallest dose of statin , twice a week. What is your BMI ? Overweight ? Eating only two meals a day and cutting calories is a solution. I've done all of these things. It works. Get your waist down below 36". .... It takes discipline.
Low triglycerides and high LDL is just how it should be. Never take statins, they cause disease ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-iOwfhFWUwhE.html
I was able to get my triglycerides down on carnivore from 199 to 56 my HDL won’t go up no matter what I do, HDL 56 LDL high of course, I have plaque I did cac scan, have trained all my life so active, it made no difference by the looks of it, from what I understand I should be reducing my LDL, I really don’t want to take statins, I already have prescription in my pocket, this is just fucked up, its impossible to avoid saturated fat on carnivore, what is the point eating red meat and fat and then swallowing a statin straight after, so confused on what to do. Thanks for the video I really needed it.
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Did you manage to reach any conclusions? I live in doubt, I did low carb and my LDL was high at 209 then it says Mediterranean diet I lowered it to 169 (still high) my triglycerides at 90 HDL 53, I don't know what to do if I don't eat fat sw I avoid it I like meat but I confess that I'm always afraid of being wrong... but I definitely had to avoid sugar and flour and take natokinase berberine k2 supplements, etc.
No unfortunately, I am taking supplements like natto, high dose of vitamin c, beetroot powder, you need to do a cac scan to know if you have a plaque or not, cos if you don’t, then you should not worry about your LDL from what I understand, but your bloods look similar to mine, I guess low HDL and high Triglycerides is worrisome. I am working my way towards becoming Lean mass hyper responder, my lipids looking similar already, I just need my HDL to be higher, I think then high LDL may not harm me any more, you could try red rice extract and citrus bergamot shown to lower LDL.
I am 53 years old now and 1 year ago i did a cac score and it was 524. Also,an ultrasound on carotid arteries in the neck,the right side a had a mild block. I went carnivore ,like 99.5 % for a year and retested both. Cac went up 100! total became 624 and the mild carotid plaque grew from mild to not mild(forgot the term) So, with my cardiologist we did a heart cath and discovered 2 blocks of 60-70percent -one in the right coronary artery and 1 in the left anterior descending coronary(the widow maker) artery at the very beginning of it. Anywho, so, for me i started 80 mg atorvastatin and it definetely cut my ldl down to 68. So,cardiologist is happy. Im hoping he's right and wont need stents or more. Also, switching back to a normal diet,but a lot lighter on the eggs and red meat, and meat in general. Will test all again in a year? If im so lucky.
@@ldx1793 thanks for sharing, it’s really hard to make decisions when you are facing this, it’s hard to know what to do, please update when you re test, I think it’s really important to share info, cos we can see what works and what don’t.
There is some evidence that with a decent amount of K2 it can help reduce or harden plaques. Look into it if you want to know more. The research is still pretty new so they will not promote it without more study.
I had my annual stress test yesterday with my cardiologist. My LDL is 192 and he wants to prescribe either Repatha or Leqvio. The side effects of both of these is not good. One being high blood sugar (diabetes). Yes, those are the words in possible side effects. I have been very strict carnivore for three and a half months, down 26 lbs and I feel ten years younger. I am 69 years old. While all of my numbers have improved he still wants me on something. I have refused the statins prescribed as well. I hope I am making the right decisions.
You may be a lean-mass hyper-responder. Dietary carbohydrate restriction leading to raised LDL and HDL cholesterol levels. It's evidently an indicator of fat adaptation - signs that you're doing your LCHF diet successfully. Medicine is only just recognizing this, and treatment guidelines enforced by national medical associations upon their doctors means their hands are tied, or their licenses are revoked... here's a link to a study, if it helps: pubmed.ncbi.nlm.nih.gov/22959954/
I got prescribed Crestor and one of the most common side effects is diabetes! No thanks.I’d guess that diabetes is a lot worse than slightly elevated levels of cholesterol.
This type of advice doesn't work for everyone. Keto 7 years, Carnivore for 35 days. I had recent blood tests and LDL was very high, HDL was low, Trigs were high, glucose was high, and two liver markers were high as well. Last test was 2 years ago and all those markers were either in the good range or heading that direction. Very confused now and concerned about plaques increasing. Looking for any thoughts people have other than to go vegan or vegetarian (they lie in their science [like in Forks Over Knives] and have no reliable RCTs showing anything conclusive).
@@christineng4938 LOL, clearly didn't read my comment, been low carb for 7 years.
Месяц назад
I'm also confused I don't know what diet to do my LDL was 209 (low carb) I did a Mediterranean diet (169) it dropped but now I don't know which direction to take...
First of all, thank you for your work. I have not studied medicine nor am I a scientist, but I read and try to understand the wise doctors, biologists and geniuses that I have met on RU-vid; conclusions that my brain can reach: -1) non-debatable: studies with follow-up of the health of thousands, and millions, of people for several years have made it clear that the total cholesterol values among people who live longer are between 190 and 250. -2) debatable: cholesterol does not start atherosclerosis, it needs damage to the artery to try to infiltrate it, (it does not stick to its inner layer because if this were so it would also do so in the areas of the arteries that have less blood flow, where it would be easier to stick, or in the veins, where it does not stick either; there must be previous damage to the artery that allows it to infiltrate). -3) debatable: cholesterol tries to repair damaged arteries and for some reason part of it gets stuck there, I don't know if it's to keep trying to repair the problem or because it has oxidized and can't get out of there -4) debatable: HDL cholesterol has to have values between 50 and 80 and triglycerides a value of 100 or less. The triglycerides / HDL ratio should not exceed 2 I hope I haven't written many things wrong... hahaha; but I'm sure there are people with more knowledge who can tell me where I'm wrong. p.s.: values in measurements of Spain, Europe
Probably not. Your Triglyceride to HDL ratio is excellent. Perhaps a CAC test to confirm that you don't have any calcified plaque buildup just for peace of mind.
I would like to tell your listeners about my cholesterol journey. The number one thing is ask your doctor to refer you to a Lipidologist or an Endocrinologist. Hopefully your insurance will allow you to ask for an ADVANCED LIPID. That measures the type of particles that are floating in your blood. I had it done. Secondly change your diet as the young man in the video mentions. I started walking everyday no matter what happens for 30m-1hr. I take Fiber powder daily, chia seeds, all types of nuts and drink a lot of water. Lastly, you have to try very hard to stay disciplined. I saw my Total Cholesterol numbers come down 30 points and my Good cholesterol (HDL) increase which is better. Always consult with your doctor. However, if he or she doesn’t know these things then you have to research yourself and be your own ADVOCATE. GOOD LUCK everyone. You can do it!!!!
You mention high blood pressure and insulin resistance as risk factors. Are they independent factors, since hypertension might be a result of insulin resistance? What is needed is a multiple regression analysis where one factor is held constant. We can then see if the second factor is still significant.
I need to get bloodwork done again, but I used to have normal trigs and highish LDL while doing keto. Once I started doing carnivore (years ago) my LDL went even higher (expected) and my trigs doubled. I'm active and fit. Also, my apoB was quite high. So I stopped carnivore. Have to recheck, but I still don't understand why that happened.
I'm amazed that Ancel Keys's remmants are still resonant up to these days. If you think about it, you will find that his hypothesis is wrong and too naive at the 1st place. The root cause is changing (in a wrong way) of *_MODERN LIFESTYLE_* . I'm also amazed that people think they still can reduce LDL to close to zero with drug intervention while staying on a couch. The Occam's razor seems to have 2 edges.
Well done! Perhaps next time clarify right away that LDL is not a type of cholesterol and stop using the misnomer "LDL Cholesterol"? Just say LDL or LDL lipoprotein. Dr Malcolm Kendrick has extensively studied plaques and noted that less than 1% of the plaque tissue examined consists of cholesterol. The rest is layers of blood clots. I used to dissect people and people parts for a living and this is absolutely correct. Large plaques in the aorta were alternating bands of pale yellow rubbery tissue and dark red softer layers. Reminded me of tree rings... Another common cause of damage to the arterial lining leading to clots, then plaque, is uric acid. Fructose is broken down into uric acid causing crystal formation that is carried in the bloodstream. High blood glucose also causes the liver to convert excess into fructose via the polyol pathway. It is also reasonable to suspect that oxalates would do the same, as they form crystals with calcium and magnesium. Both types of crystals look like needles under the microscope. I read a small study from autopsies done on HIV patients with atherosclerotic plaques. The plaques were analyzed for oxalates and the plaques were loaded with the crystals. Unless tissue specimens are processed differently than the standard procedure, the crystals dissolve in the alcohols. You can microscopically see sharp outlines where the crystals were, but won't know what kind of crystals unless specifically processed and stained.
My LDL is very high because of genetics. My HDL is low, and triglycerides are high. I am 22 years old do weight training, recently had the ct scan and echo tests for heart and all the reports were normal. What to do now?
There where autopsies done on kia’s during the Korean and Vietnam wars. The plaque formation was present i most of the soldiers and about 5% had allready servere plaque. Is ldl the only cause or is it an agent needed for some other process?
Talk about begging the question. They ASSUME LDL-cholesterol is the causitive agent, in the presence of other inflammatory agents, with no regard to oxidation or glycation of the LDL. It's motivated reasoning, ie biased analysis. Crap science. You know this, Mike! I know you want to be careful, but this LDL-cholesterol model is seriously flawed. Your dietary advice, however, is spot on. But the heart-cholesterol model is garbage. (Okay, you finally got there.)
I did a battery of test with a cardiologist and at 63, male w a CAC score of 62 I was surprised because I have had high LDL my whole life and low HDL and I thought the number would be over 100 at least. Since my LDL was 180 he wants me on Repatha. I said ok but I didn't research the side effects. I am intolerant to statins so I assume I will have side effects from Repatha. Now he expects me to take it. Has anyone taken this? Other sites have some very bad stories of people with permanent damage from even taking 1 dose.
I have high LDL - I practice IF, low processed foods, sugars, breads, seed oils, don’t smoke, not obese, exercise & strength-train. Average triglycerides. Yet I am on high blood pressure medication (10years) - due to genetics- Dr says. total cholesterol is high but my HDL is extremely high- almost off the charts. What Is the correlation between ldl & hdl in assessing my high cholesterol score?
I do the same . The doc put me on BP meds which I stopped years ago and BP is never better . Thank goodness I didn't listen and did what I thought my body needed . I keep an eye on it myself
Is it true that children with FH as young as 2 years old get ACVD. IF its not the LDL , then what causes it ? I want to believe just LDL is not causal but this is bothering me.
