Everybody wants to live longer, live better, and extend life to the fullest extent. Learn about how sprinting can increase telomere length and have anti-aging effects. Also covered are a couple supplements which are being studied for life extension and anti-aging purposes.
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Sprinting Delays Aging
A group of Brazilian scientists ran a study that looked at the telomere length of master’s sprinters compared to a control group. The sprinters ranged in age from 40 to 70 years old, all of them being fairly competitive in their age groups. The sprinters had been active for at least 10 years prior to the study.
In looking at the two groups of sprinters and non-sprinters, the sprinters showed significantly longer telomeres than that of the control group. Furthermore, the fastest masters sprinters had the longest telomeres.
The sprinters with longer telomeres showed a smaller reduction in sprinting performance as their ages increased. Taken together, this suggests there is a relationship between telomere length, sprinting ability, and the aging process.
The researchers admit that they do not know the causal relationship between telomere length and sprinting, meaning that sprinting may increase telomere length or telomere length itself may increase sprinting performance.
The researchers stated that the results of the study do indicate that high intensity training, such as in the form of sprint training, does have a beneficial effect on the bio-molecular level, including in middle-aged adults such as the masters sprinters in the study.
They suggest that high intensity training like sprinting should be performed by adults, and older adults, as a way to mitigate the aging process.
Supplements For Anti-Aging
Now, if we are already sprinting for exercise and getting anti-aging benefits from that, the question becomes what else can we do to slow the aging process?
There are certain supplements which research suggests can help maintain telomere length, reduce the effects of aging, and through that possibly extend life.
NMN - Nicotinamide Mononucleotide
Popularized by David Sinclair, NMN or Nicotinamide Mononucleotide, is a supplement that looks very promising as it relates to preventing aging and maintaining telomere length. NMN increases levels of Nicotinamide adenine dinucleotide (NAD+), a coenzyme that is central to metabolic function. NAD helps give you energy from food, but also prevents DNA damage and promotes healthy cellular function.
One study was performed which looked at the effects of short term effects of NMN on metabolism, the microbiome, and telomere length in pre-aging phase mice and middle aged adult humans.
NMN was shown to modify the microbiome of the study participants. More interesting was the fact that NMN supplementation was associated with longer telomeres, and that NMN ingestion could actually increase the length of telomeres. These effects were present within 30 days for humans and 40 days for mice.
“Further, we observed longer T in both the mice and volunteers with NMN supplementation and reported for the first time that NMN could elongate the length of the T in a clinical study, suggesting the potential of NMN use at a pre-aging phase to retard the proceeding of aging.”
Essentially, the researchers suggest that NMN may be useful to take prior to the onset of aging in order to delay any negative effects the aging process.
Resveratrol
Resveratrol is another supplement that has been studied thoroughly. Resveratrol has been shown to extend life in mice, as well as having beneficial effects related to cardiovascular health, preventing sarcopenia or age related muscle loss, inhibiting inflammation, improving mitochondrial function, and regulating apoptosis or planned cell death.
Resveratrol helps stimulate Sirtuins, which are cells that regulate cellular senescence and prevent the breakdown of telomeres. These cells are also related to the beneficial effects that calorie restriction and exercise have on health.
Resveratrol supplementation has been shown to extend life and longevity in yeast, fruit flies, and mice. In primates, resveratrol has been shown to protect the cardiovascular system against the effects of high-fat high-sugar diets, as well as improving insulin sensitivity. In humans, resveratrol has been shown to delay cognitive declines associated with Alzheimer’s disease and to help affect the metabolism of obese men.
31 май 2022
