Cellular Respiration Part 1: Glycolysis

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You need energy to do literally anything, even just lay still and think. Where does this energy come from? Well, food, right? But how? This is one of the most miraculous biological processes, and it happens in our bodies every moment of every day. It's quite complicated, so let's check it out in three sections. First up, glycolysis!
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29 сен 2024

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Комментарии : 250

@beauthetford7608 4 года назад

you're way better than my textbook and my professor combined

@carliekeeton4780 2 года назад

When I graduate med school I will be making a hefty donation to this guy. He has saved my butt.

@GeeThekiNg Год назад

same here

@francissapp6577 10 месяцев назад

Update? Did you graduate yet?

@imawakemymindisalive13 9 месяцев назад

actually you will be deep in student debt, maybe a decade or two after graduation though?

@francissapp6577 9 месяцев назад

@@imawakemymindisalive13 well damn

@hehegahahah 7 месяцев назад

😂@@imawakemymindisalive13

@Tekamizone2464 3 месяца назад

Trillion thanks to you

@ahmadhegazy7811 5 лет назад

1. Any glucose can enter glycolysis either beta or alpha right ? 2. I think the net overall equals 8 atp ( 2 ATP + 2 NADH ) Because starting from step 6 or after producing 2 GADP we will double every nad or atp So from step 6 to step 10 we will have 10 atp Minus 2 atp from the first 5 steps the net overall equal 8 atp What do you think?

@derekdurrett1905 6 лет назад

Thanks, for the video and chart!

@diamond_gypsy7452 2 года назад

you just saved my butt!

@Makesnosense2 2 года назад

Yeah this the one

@ThaoNguyen-iv1xq 6 лет назад

beautiful

@Fabrisend 5 лет назад

What is phosphorilex

@aidanward7510 2 года назад

King

@khalidalnajjar5261 3 года назад

thanks bio jesus

@kho5254 4 года назад

what about pyruvate oxidation??

@ProfessorDaveExplains 4 года назад

check out the next tutorial

@kho5254 4 года назад

@@ProfessorDaveExplains oh! thanks I found it :)

@viancechavez5089 11 месяцев назад

why are you yelling at me 😣

@yashgokhale1460 7 лет назад

You have explained me concepts in 8 flat minutes which I did not understand in a two hour lecture. You are a legend Sir! P.S. The introductory song is very catchy.

@sccm100 7 лет назад

HE KNOWS A LOT ABOUT THE SCIENCE STUFF! PROFESSOR DAVE EXPLAINS!

@MohamedReda-gd2zo 5 лет назад

exactly like me . Thanks Dr/Dave.

@syedshadmansakib 3 года назад

HE KNOWS A LOT ABOUT THE SCIENCE STUFF! PROFESSOR DAVE EXPLAINS!

@ismartmoher9154 Год назад

@@syedshadmansakibsame here😊😊

@yoanastankova5076 11 месяцев назад

Now, imagine you are binge-watching 1-2 playlists. I hear this song in my sleep. Still Prof.Dave = the GOAT.

@booloob 8 лет назад

you are a present to the world man i'm a loyal subscriber keep up the detailed interesting videos your THE MAN!!

@ProfessorDaveExplains 8 лет назад

thanks for watching!

@witty_me 4 года назад

This 8:11 min. video is much better than a one hour class, and that table at end which comprises all the important details and names of enzymes are mind blowing.Keep helping us like this. Thanks😀

@94cd5 8 лет назад

Thanks again Professor Dave, so far you have a video for all the topics we are covering in Biology. The videos are really helpful, I watch them after I read a lesson. I introduced one of my classmates to your videos. You are appreciated.

@ProfessorDaveExplains 8 лет назад

thanks kindly! happy to be of service

@maureenkaluba6305 3 года назад

Fell into depression cause I couldn't understand this topic in time for my med exams ...but wow ...that was so short, simplified but detailed at the same time🥺❤️👏 thank you professor God bless you

@alanmunoz5621 7 лет назад

sooo basically, Glucose (6C) splits into 2 (3C) Pyruvate 1. 1 phosphate added to 1 side (-1 ATP) 2. 1 phosphate other to 1 side (-1 ATP) 3. 6C splits into 2 C3 4. Hydride (H-) removed from each, reducing 2 NAD+ to NADH (or FAD+ -> FADH2?) . 5. Hydrides are replaced with an inorganic phosphate on both (not from ATP) Now, 2 P’s on either side of both GP3’s) 6. Phosphates on either side of both molecules then split and go to ADP to create 4 ATP, becoming 2 Pyruvates (3C) NET = 2 ATP & 2 NADH

@maysk.5998 3 года назад

so what is the difference between the 2 C3 (step number three) and the 2 pyruvates?

@flamesblades 3 года назад

@@maysk.5998 I’m learning this myself, but I think it’s the fact that the pyruvates get phosphorylated in step 3 by phosphofructokinase 1, and they get dephosphorylated, or lose a phosphate group, to replinish the ADP’s into ATP again.

@leslieaharden6183 Год назад

Thank you. Have been watching your DNA videos to supplement my biology class at UT in Arlington. Work in Engineering for the VA hospital and decided to study nursing. Thank you for clarifying!

@Joel-fs5zh Год назад

you are literally doing God's work. Been with me since a freshman. I am now in my Junior year. LEGEND.

@joelsteve5396 Год назад

thank u for making it uderstandable to a 10th grade student

@malindaeckert2300 4 года назад

Dying laughing.. have no idea.. completely lost on the verbs you're using 😭. Imma have to Google so many words lol

@kimberlybenjamin9284 7 лет назад

i always search your channel when it comes to biochemistry, thank you for sharing this video! it really helps us. your video is much better than the other channels because it was more precise and your speech was clear. :) and btw, im from the philippines :) i will share your channel to my classmates!

@ProfessorDaveExplains 7 лет назад

please tell everyone to subscribe!

@aanandakrishnan8285 3 года назад

@@ProfessorDaveExplains You are one of the best.Why does she need to tell everyone to subscribe. Watching your lectures our hands automatically moves to click the subscribe button.

@adeelkhan898 Год назад

@@aanandakrishnan8285 hello I am adeel

@adeelkhan898 Год назад

Professor where from you

@mijellerose 7 лет назад

I wish I found you sooner. This video was so helpful for me. I have one more biochem test after the one I watched this video for. I'll definitely be watching more this semester!

@j.g.1622 6 лет назад

This is very comprehensive, well-explained, and easy to follow compared to a lot other vids on the topic. Thanks a ton for making this.

@mills593593 8 лет назад

Cool, I am a DNA chemist, so I never learned about metabolism but I also new ATP was involved. Now I can see how are food is used to generate ATP through this cycle :) I heard we make 80 kg of ATP a day, pretty crazy synthesis scale!

@ProfessorDaveExplains 8 лет назад

holy smokes, that sounds like too big a mass! but i suppose it could be true.

@NewWesternFront Год назад

hows it going? what do you do as a DNA chemist?

@MemeMaterialz 2 года назад

Thanks science jesus❤

@rayanaalo6022 7 лет назад

This video helps me in my biochemistry exam ... Thank you 💜💜

@akrutimishra2430 7 лет назад

you deserve more subscribers !! you helped me by sharing this video and now I'm gonna help you by sharing your channel to my mates

@ProfessorDaveExplains 7 лет назад

woo! that's all i can hope for!

@tobiasklein8719 Год назад

yaas queen

@wagnerlopes5360 5 лет назад

Another great class and another confirmation of outstanding machine our body is!

@arrisyaamran3301 7 лет назад

Such a great explaination ! U help me a lot

@o.t.2473 2 года назад

Wow! You made this way easier to understand than by biology professor has. Thanks!

@drosha9314 7 лет назад

you brilliant, brilliant guy! thank you so much.

@joshualumbe1842 Месяц назад

When I graduate i will comeback to thank you more professor dave🙏🤝. Hopefully donate!!. From premed to preclinical you've saved a dream🤝

@AnuragPradhan101 7 лет назад

Thank you very much professor Dave, Just because of you, I'm surviving in my college, If you don't mind, I have a request, can you please add all the notes used in your videos in pdf form to download, so that after watching all of your videos we can once again revise everything that you taught by going through the notes that were used in the videos in a quick way.

@ProfessorDaveExplains 7 лет назад

i don't have any such notes unfortunately!

@bippy201 5 лет назад

Making your own notes from his videos would be a great way to study!

@NewWesternFront Год назад

@@bippy201 shut up and spoonfeed us Liz

@1stchoicetax715 2 года назад

I can’t thank you enough I was understanding then my instructor got to glycolysis steps and I was like 🙅🏾‍♀️🙋🏾‍♀️🤷🏾🤦‍♀️🤯😭 and now after watch this I’m like😲🤔👩🏾‍🎓👩🏾‍⚕️

@Marytere8 Год назад

Tengo entendido que una sola molécula de glucosa puede desencadenar las reacciones de respiración obteniendo cómo producto final 38 ATP's ¿Estoy equivocada?

@Zetsuke4 4 года назад

This is incredible! one of the best version I've seen. this guy's a genius!

@patrickmarkflores6027 2 года назад

thank you for this video prof. I almost spend 5hrs in watching other videos about glycolysis from various channel but thanks God your explained it very well. You're the living Gift from God for me.

@thedisintegrador 7 лет назад

This is just way too good. I find myself watching these just out of curiosity and not because I need it... When I think about it, I need this more than anything. Just knowing it is awesome. Thank you for your effort

@ProfessorDaveExplains 7 лет назад

that's the ultimate goal! people watching just for fun and general comprehension. spread the good word!

@Jovinzy-eb6ns 3 месяца назад

Thanks professor Dave for clear explanation compare to my previous lecture which takes me a number of hours to understand but not real.❤❤

@DOCB-op1qc Год назад

are these steps really consuming an "ATP"? or is the reaction catalyzed via the use of a phosphate group on an ATP ? & the the adenosine portion & as well as 2 phosphates remain in action. i hear u can use ADP to power reactions but not AMP, & also they can be re" phosphorylated "to recycle & reuse. but i have no idea where i heard that or what to google to review the answer.

@dawitabebe Год назад

Wow You are intelligent I really appreciate you PROFESSOR DAVE!!!

@sccm100 4 года назад

Thank you for existing. Sal from KA drives me nuts with his off-topic talking.

@vegan__girl 2 года назад

Omg I have an exam tomorrow and you summarized the whole lesson in this video, thank you sm, this really made the studying process so much more simple for me.🖤

@Bot-tm7hs Год назад

so if we only use glucose as energy (except during ketosis), why aren't proteins and fats in food zero net calories for us?

@claudialatty4041 11 месяцев назад

Professor Dave is do no understand metabolism and how the Krebs cycle works can you help me please

@surajprasad4742 Год назад

From where Phosphorous is coming in glucose phosphate after the reaction (hexokinase).

@kimberlyhovis5864 4 года назад

Thank you for making that very easy to understand. I've been struggling with this concept lately, and now I understand it. Thanks!

@zinimbita9789 4 месяца назад

Excellent, you made so each to follow and understand. Thank you Prof

@robinlazulite3167 7 лет назад

Thank you for simplifying this complex process...helped a ton with studies!

@ownwrites Год назад

Didn't get thy concept of dehydrogenase here in that NAD phase sir?????

@jodyemanuel6371 4 года назад

Professor Dave! I! LOVE! You!!!!!!!!! I finally see the light 💡 Hallelujah 🙌

@javiersalinas7323 4 года назад

My professor recommended me this video and is just Gold! I can't believe a good video like this exists

@shaikrehanaparveen8862 4 года назад

This is absolutely awesome

@m.r.5129 Год назад

Thank you

@flukeseawalker 7 лет назад

Two Thumbs UP! :)

@anupamakaim4169 3 года назад

Thank you sir you helped me in my last hope when I am stucked with these concepts thank you sir

@rip_goat958 4 месяца назад

Using this to study for my 2024 IB biology exam

@tejaswininaragude1739 2 года назад

Just one question ..do you make lesson plan befor the video..?

@ohemaapokuah6981 6 лет назад

thank you Professor...your videos are really helping me in all my biochemistry exams...keep it up🙌🙌

@lostboi3974 5 лет назад

I didn't know Jesus was a RU-vid scientist but 🤣🤣🤣🤣🤣🤣🤣

@elmijeselmani8682 3 года назад

which is the source of of the phosphate group like how i cant understand

@lucinaroopal3122 8 лет назад

very nice. Thank you

@MasayoMusic 6 лет назад

Have you upload that chart at the end somewhere? It would be useful to print it out!

@ProfessorDaveExplains 6 лет назад

just put the clip in full screen mode and take a screenshot! command-shift-3

@jocimor1 3 года назад

Thank you for actually going through the ten steps with each enzyme!!!

@fairbecca2 6 лет назад

Thank you, thank you, thank you! Clear, concise, and linear, your teaching method rocks!

@emelierivera4242 11 месяцев назад

Its currently 8:15 am and I am watching these videos to pass my midterm later this afternoon LOL

@harperpater7398 10 месяцев назад

did u pass

@NeilNileStudios 4 года назад

Lol I️ watched this in bio 1 and skipped 3:33. Now I'm back for biochem and thankful that your're going over the reactions in 3:33

@sreereddy030 6 лет назад

tnq professor Dave, u made me easy 2 understand glycolysis

@rittenbrake1613 6 лет назад

very clear thank you so much

@randomlylegend 3 года назад

I’ve watched few videos on the subject and all of them are talking about “generating” energy(ATP) from the reaction of glucose and oxygen. Like ATP is a product of the process. Obviously you cannot create a molecule with P and N atoms in it by combining C,H and O atoms. The way I see it, you need ATP to make more ATP. Where the very first ATP comes from? It is produced by the body itself? Thanks

@ProfessorDaveExplains 3 года назад

This a three-part series, please watch to the end.

@sydney.4u Год назад

im going to cry, pls let me have a 90% on the test

@garysgroundschool4739 2 года назад

Wow I used to watch you flat Earth videos a while back but now here I am studying for my introductory biology class. A true man

@jacobunderwood4691 5 месяцев назад

I can’t believe this guy was in nirvana

@a.s.7775 7 лет назад

Thanks! I've just managed to go through all my notes with help of your videos(Biochemistry) to see if I missed anything. You saved my life! You also made it easier for me since you made a playlist with all the videos from Biochemistry (Y)

@ProfessorDaveExplains 7 лет назад

my pleasure!

@trixxy7104 11 месяцев назад

I wanna say thank you so much because I got a 22/18 on my bio test while everybody else got 10-15’s 🙏🙏

@martasienkiewicz4486 2 года назад

Love your videos! You are building up quite an impressive and broad reperoir:) They are so great to catch the main ideas and concepts and to get some overview before embarking on a proper heavy reading:) But in this particular video the analogy of a living organism to a machine catched my attention. Because there is much to philosophise about this kind of perception. I'm reading a book titled 'The Turning Point' written by Fritjof Capra and it is basicly a book about the need of revolution in the modern science as well as our western culture rooted in mechanistic understanding of pretty much everything. I wonder if you will jump into this kind of stuff in the future. I mean covering the science of philosophy:) I'm studying Molecular Biology but I'm totally into having broader perspectives upon... Yeah, everything I gues: metaphysics and what not.

@counterculturecocks 6 лет назад

Thank you, sir! I have a gigantic exam in just a few hours. This was the icing on my 'cake' of study! Fills in the blanks and provides short, but thorough, explanations. You've got a subscription out of me.

@bslaozora 3 года назад

If I'm correct in my google ability in some slides you shows the conjugate acid while naming them as the conjugate base 🤔 Hope I'm not making a mistake (My chemistry is really bad so that can be confusing for me) It's otherwise a super helpful video anyways!

@OnnumMuttaiyum Год назад

Now the problem is to revise and remember 😢

@teazen_tea 7 месяцев назад

This video is going to save me. I did not explect the first class in my biology minor to be quite this memoriztion heavy.

@tonifriedrich7191 Год назад

How can you reduce with a proton?? 2:08

@JMYaden 6 месяцев назад

Fantastic, clear explanation of a complex biochemical process. Thank you, Prof. Dave!

@yvonnemukupa1670 2 года назад

You're the best professor Dev. Much love.

@attouab 3 года назад

A lot of videos repeat things "atp stores energy" and "you get energy when a phosphate group is released" but they don't explain it and probably they themselves don't know what it means. Professor dace does a good job at explaining it

@mohdadlymohdarif8674 4 года назад

Sir I know where 6 oxygen, 6 carbon dioxide & 38 ATP comes from but where does 6 water originated?

@janetonuorah6313 Год назад

Notes for myself 2:57-glycolysis 7:08 too

@mosalah151 3 года назад

Really You're genius person...

@DeclanOKaneMD 4 года назад

Isn't it all simply about the electronegative oxygen stealing high energy electrons. I think we get to focused on the steps and not the fact that its taking energy from glucose's carbon high energy electrons. I'd love you to talk more about this or have I got it wrong.

@ProfessorDaveExplains 4 года назад

You're talking about the electron transport chain. This is a three part series.

@DeclanOKaneMD 4 года назад

How does glucose contain energy. In what form. Where is it stored. If u say the bond then where in the bond. thanks

@ProfessorDaveExplains 4 года назад

It's chemical potential energy. It sounds like you need to go back to my general chemistry playlist and learn about what chemical bonds are.

@DeclanOKaneMD 4 года назад

@@ProfessorDaveExplains That's very useful. It is just that I can't find anyone except perhaps you who brings it all together. Fundamentally if I have got it right its about orbital electrons and their position and potential energy. An electron far from the atomic nucleus has high energy. I will go and watch more of your wonderful videos. Thanks