Wonderful job, I would have added that T cells going thru maturation in the thymus are, initially, both CD4+ and CD8+. This is important to make sense of the fact that they can be presented antigens by both the MHC2 and MHC1, respectively.
What is the evolutionary point of the recognising by T cells of microbe-derived peptides, which had been processed and displayed on the antigen-presenting cell membranes, in-stead of recognising microbial antigens itself?
great video but weird voice.. does not sounds natural. After watching 2 or 3 videos of this channel it really gets annoying. please don't take me badly. The content is fine and helps a lot. thanks
Why does autoreactive b cells or autoreactive t cells get develop ??? If these cells have to get killed by negative deletion.?? These autoreactive tcell or autoreactive b cell escape from negative deletion, then they remain in dormant state in the blood , then conditions make them active e.g when foreign antigen act like self antigen then these autoreactive cell can become active. Please answer