Great conversation! Also love Prof. Luigi Fontana's youtube channel. The problem I see is, how to do 20-25% CR daily while still having a active lifestyle doing exercise and building muscle. Seems a slippery slope that can lead into malnutrition. Especially, for the large human population. Not many people count calories.
That was fun to listen to. And great questions. Thank you! Prof Luigi's excellent accent reminds me that we haven't heard from Prof Longo in a while. I wonder if we can have him back to hear about recent progress with some of his studies? Also, after listening to Dr Farenbach's recent talk, I wonder if markets of kidney function might serve as markers of aging?
The American healthcare system is a profit making system, there is no money saved, customers are lost. Theoretical money saved only applies to socialized systems, and even then savings are not realized. Governments do not lower taxes because social health improves. Contrary.
As a 64 yrs 18.5 bmi lifelong athlete w/a bum knee . . . CR does not seem the least bit wise. And losing any sort of body mass/weight a non-starter. Perhaps I’m in that ‘rare’ 10% cohort - but how to eat for optimal health/increased mass? Thank you…
You are already calorically restricted. Starting with a weight A and cutting calories by 20% will not cause you to lose weight forever, you will stabilize at some (lower) weight B. On a population level, assuming equal activity levels and stable weights, a person with a BMI of 20 is some percentage calorie restricted from someone with a BMI of 25, otherwise they would be gaining weight. Since you are light, compared to the average person, you are in the 'calorie restricted' population already!
Protein and fat restriction is essential for any significant benefit from caloric restriction. Low protein low fat high carbohydrate diet is what works the best.
