Your style of lecture and presentation of the information in the background whiteboard is by far the most effective out of all the lectures I've seen. You got something great here.
TMHTNN Thank you, I appreciate the positive feedback! It takes a while to get the notes together and transcribe them onto the board, so its wonderful to hear that you're enjoying this form of lecturing :)
out of all the lectures on tca i've seen on youtube this was by far the most helpful- not only did you cover the information needed to understand the tca but you're also prob the only person who explained why the steps are happening so well!
You are amazing! This has helped a lott! I have a question if you can please answer.. our professor didn't really explain this but it is often in the exam: when you mark a carbon in oxaloacetate 14C, at the end of the CAC, which carbon will be marked? thank youu
ok can i just say how comprehensive he is and how WELL he knows his biology? I listened to it in full, then I listened to it at .75 speed to take notes. I really am liking this guy
dude your lectures are so so underrated, your notes are very helpful and easy to understand...exposure is whats missing here i think your notes can help a lot of people..
I really appreciate the work that you have put into this. If it wasn't for you I wouldn't be able to grasp a full understanding of these. I learn from your presentations and feel a real sense of accomplishment. Because of this I feel more confident in class. Cheers so much!
I can't hank you enough.. This just shows that there is no hard material, but there is only bad professors......... Thank you for making this so clear!!
AK i love your lectures! SO many have helped me while preparing for my USMLE step 1! but in regards to the TCA cycle, I have a question, why are there are total of 4H+ per glucose molecule rather than 6? Isnt one H+ produced with each NADH?
Great lecture! Very clearly explained. My only Q concerns the H+ IN STEP 8. That H+ does not get tallied in the final product count. The final product has 4H+ (2 *2H+) from steps 3 and 4, but there is an additional H+ formed in step 8. Q: Why don't we include this H+ as a product, making the total H+ formed 6H+?
Why don't you count for the other H+ ion that is produced in the last step? You said we have 6 NADH, so shouldn't we also have 6 H+? From steps 3, 4 & 8?
+Sigrid Kite You are right, but I think he knows that for sure and probably forgot to mention it or just missed it. It happens sometimes :). However I think this man (AK Lectures) did his job perfectly!
Thank you so much for doing this video and the others! They have been so helpful for the online classes I am taking for my nutrition masters. I appreciate your teaching style, and how you go step by step and everything fits on one board! : ) Thank you!
Can you explain why there are only 2 coA produced? Shouldn't there by 2 more from the first step where OAA reacts with water to decarboxylate acetyl coA? There is a coA produced in that step. Also is there a net input of 4 molecules of H2O?
This is a great source for reviewing, as well as learning for the first time! Thanks for the time you invest in making these videos (: Do you have a video where you also go in depth about the mechanisms behind each of the enzymes in the TCA cycle, by any chance?
Rebecca Bartke Thanks Rebecca. This lecture was a biology lecture and so it was not meant to be in-depth. But I am currently working on biochemistry and am planning on making a lecture on that, so definitely stay tuned.
Rebecca Bartke Also Rebecca, I think you asked about playlists a while back so I managed to organize some. I will continue organizing the biochemistry ones into specific chapters and such.
please help: Explain where in the CAC a hypothetical defect of an enzyme could occur that would decrease the overall ATP production of the mitochondria, including each of the following: ● whether the entire cycle will continue to function ● what will happen to the cycle products ● why ATP production decreases
I think there would be 6 hydride molecules H+ produced in the CA cycle since there are 3 of them produced in step 3,4, and 8 in each of two cylces. Any explanation here ?
Is it same CoA that migrates from PDH complex to @-ketoDH complex after getting kicked out from Acetyl CoA or each of these complexes have their own CoA?
In the process of glycolysis link reaction and citric acid an (overall) 8 NADH+ H+ and 2 FADH2 is produced, this happens in a reaction where NAD+ 2H+ +2e and FAD --> FADH2, This meaning, when prodcuing 8 and 2 of these electron carriers we need 24 hydrogen, but glucose only has 12 hydrogens so where do these 12 other hydrogens come from if it does come from glucose cause it simply doest have that many hydrogens, does it come from water that is used in krebs cycle or i dont know ..please help me
hey aka can u explain about the very first step of TCA cycle i.e formation acetyl co-a from pyruvate because there is a enzyme complex that is carrying out this reaction which is very difficult to understand