Clearance and Rate of Elimination - Pharmacokinetics - Pharmacology Lect 12

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This lecture covers clearance and rate of elimination. View the other videos on pharmacology below.
(1) Pharmacokinetics & ADME: • Pharmacokinetics for S...
DRUG ABSORPTION Videos:
(2) Drug Absorption Overview: • Absorption of Drugs - ...
(3) Bioavailability: • Drug Bioavailability O...
DRUG DISTRIBUTION Videos:
(4) Drug Distribution Overview: • Distribution - Pharmac...
(5) Volume of Distribution: • Volume of Distribution...
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DRUG METABOLISM Videos:
(6) First Pass Metabolism: • First Pass Metabolism ...
(7) Phase I Metabolism: • Phase I Metabolism - P...
(8) Phase II Metabolism: • Phase II Metabolism - ...
(9) First Order and Zero Order Kinetics: • First Order & Zero Ord...
(10) Drug Half-life: • Drug Half-life | An Ov...
(11) First-order elimination rate constant and half-life-details: • First Order Eliminatio...
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DRUG ELIMINATION / EXCRETION
(12) Drug Clearance: • Clearance and Rate of ...
(13) Renal Excretion of Drugs: • Renal Excretion of Dru...
(14) Ion Trapping: [not yet posted]
(15) Dosage Regimens: [not yet posted]
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Factors That Affect Drug Metabolism:
(16) Enzyme Induction: • Enzyme Induction - Pha...
(17) Competitive Inhibition Overview: • Competitive Inhibition...
(18) Competitive Inhibition of Statins: • Competitive Inhibition...
(19) Acetaminophen toxicity (Clinical Correlate): [Not yet posted]
(20) Pharmacogenomics Overview: • Pharmacogenomics | Asi...
(21) Slow Acetylators - Pharmacogenomics: [not yet posted]
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Опубликовано:

15 сен 2024

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Комментарии : 36

@redak679 5 лет назад

Wow, I just discovered your channel now and I'm surprised how I didn't come across it earlier. Thank you so much for the videos, all of them are extremely helpful. Please keep making more.

@phoenixhelicase98 5 лет назад

" I want to be clear here " ... haha ! what a perfect line for the video.

@kim-dannguyen2332 10 лет назад

I'd like to thank you for doing these videos. They are helping me so much. I've had a hard time trying to understand the concepts in my textbook but now it's ALOT clearer!!!!!

@pohsstudio7769 10 лет назад

Hello, thanks so much for the videos, I love them. I have one question though. Is the elimination rate constant the same as the rate of elimination in this video? How are the 2 related? Really confused.

@damarisgarcia87 10 лет назад

Thank you soo much for posting this. It makes so much more sense.

@citadel7925 11 лет назад

I really loved your lectures - my request is I could found anything amongst your lectures, which would cover subjects regarding - Achieving Steady State, Therapeutic window, Plateau Principle, Rate of infusion and Effect of loading dose as a logic continuation of drug elimination part of Pharmacokinetics. Anyway, thanks much, keep it going, bright clear lectures! Well Done.

@henamadi3175 9 лет назад

Thanks for these videos, really helpful. Please keeping producing new videos

@antonioluparelli5509 7 лет назад

From an Italian medical student: THANK YOU

@KP-zh8fn 5 лет назад

Thank you so much for this video! It was so clear and I’m grateful for all the effort you’ve put in. It helped me a lot :)

@minah549 10 лет назад

What happens with CL when we are in 0 order kinetics? When you look at the graph, CL is constant at 1st (green slope or 1st order kinectics). But does the CL go to zero when we're in 0 order kinetics? When I think of it logically, it doesn't make sense. Our bodies won't stop filtering just because we've maxed out our kidney's capacity... right? Someone help!

@pokerater4463 5 лет назад

According to goodman gilmans " clearance is the volume of plasma cleared of drugs per min per kg of body" so unit will be ml/min/kg. But u are saying it is ml/min.....im confused now