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DNA Damage Response 

Nymus 3D
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Illustrated is the power of combined interference with different DNA damage response processes to combat cancer: Homologous recombination, which is selectively deficient in the tumour due to the BRCA defect, and base excision repair of single strand breaks, which is blocked by the administration of PARP inhibitors.
Client:
Dr. Rini de Crom
Dr. Marja Miedema
www.erasmusmc.nl, 2014
www.ddresponse.eu/
Funded by the 7th Framework Programme of the European Commission in the theme Health.
More videos from DEMCON Nymus 3D on:
www.demcon-nymus3d.nl

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16 июл 2017

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Комментарии : 837   
@simpleidea2825
@simpleidea2825 Год назад
Thank to all those doctors and scientists that enable us to understand our complex body and also saved millions of peoples.
@mr_derpaderpy4107
@mr_derpaderpy4107 Год назад
doctors dont discover diseases or find their cures, scientists do
@artemack9358
@artemack9358 Год назад
@@theeditor1072what for?
@ritu-p6013
@ritu-p6013 Год назад
@@artemack9358 to give us brain and all knowledge
@Rikka_V1
@Rikka_V1 Год назад
I hate those scientists because now as students we need to study all of it. How tf did they discover these anyway. They should had just focussed on politics to save people instead.
@Goutham1826
@Goutham1826 Год назад
@@Rikka_V1 you should be 9
@danielpopadic4314
@danielpopadic4314 3 года назад
I love how you can explain such difficult to comprehend topic to people with 0 health knowledge by using animations , if I had to learn it from book or just text I would waste hours trying to picture 🖼️ the movements in cells
@outofthebox9699
@outofthebox9699 Год назад
Yeah and it just randomly evolved, just like Smart Phones.
@sahasra_loveyourself_
@sahasra_loveyourself_ Год назад
Yes fr
@derickd6150
@derickd6150 Год назад
@@outofthebox9699 Ahhh right and we also just randomly found dinosaur bones that the same science that made this video also tells us is millions of years old, not to mention various shaped skulls dating back hundreds of thousands of years. You can't pick and choose which parts of science you believe
@outofthebox9699
@outofthebox9699 Год назад
@@derickd6150Get lost sick punk, ur brain is too dumb to understand what I said.
@el_chico1313
@el_chico1313 Год назад
@@outofthebox9699 ur stupidity just randomly evolved like a byproduct of nature u clown
@alienspecies6872
@alienspecies6872 Год назад
As a biology student I can say this is amazing.
@outofthebox9699
@outofthebox9699 Год назад
Yeah and it just randomly evolved, just like Smart Phones.
@vunknownvictory
@vunknownvictory Год назад
I hate that I can understand in RU-vid, but not in class😅
@bittertruth4847
@bittertruth4847 Год назад
@@outofthebox9699 sound as logical as god allowing marriage between a 6 year old and a 54 year old 🤡
@_dyson
@_dyson Год назад
As a maths students this amazed me also
@UV_Lightning
@UV_Lightning Год назад
@@outofthebox9699 Yes, through billions of years of trial and error.
@anuskaroy7640
@anuskaroy7640 Год назад
God bless all doctors, nurses and good scientists
@blueshoregaming1591
@blueshoregaming1591 Год назад
I love how you said "good scientists".
@as_if
@as_if Год назад
Good doctors, good nurses
@Lousy_Bastard
@Lousy_Bastard Год назад
Plenty of bad medical professionals about this planet at this present time, who will never be forgiven for what they have done.
@ariankhan8371
@ariankhan8371 Год назад
@@as_if before good doctors and good nurses You should say good scientist than say doctors and nurses Scientist test science before doctors than doctors apply that tested science on patients Big salute to scientists who pulled humanity from pandemic
@thakursakshi_997
@thakursakshi_997 Год назад
Good teachers are also in the line of blessing🙌
@dis9078f
@dis9078f Месяц назад
As an engineer student I find it absolutely mesmerizing
@colbyandbrennen3543
@colbyandbrennen3543 Год назад
The human body never fails to impress me learning through animations like this
@wakzies
@wakzies Год назад
SHOW YOUR HUMAN BODY 🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥V
@kookimers6809
@kookimers6809 Год назад
This is all we need...well done!! Even non medical or bio student/person can understand these easily
@rgw5991
@rgw5991 7 месяцев назад
men get cancer too. sheesh.
@JoshCaiLovzu
@JoshCaiLovzu 2 года назад
0:50 homologous recombination repair... the solution is just jaw-dropping
@indiabiologyexplains5013
@indiabiologyexplains5013 Год назад
It's also essential in CRISPR cas9 editing
@unitedstatesirie7431
@unitedstatesirie7431 Год назад
Chlorine Dioxide pulls away the ELECTRONS from the Cancer cells. No harmful effects to body parts. This is the hidden cure for all types of Cancers.
@mihaelwolrk2143
@mihaelwolrk2143 Год назад
@@indiabiologyexplains5013 One question, with CRISP you can change your hair from curly to straight.
@3alaiyer
@3alaiyer Год назад
Indeed, God is the best of creators.. We’re not even aware all these things are going on in our bodies
@unitedstatesirie7431
@unitedstatesirie7431 Год назад
@@3alaiyer if you want more cure details send me you e-mail address.
@BillKinsman
@BillKinsman Год назад
My mother, grandmother and sister all have this gene mutation. I may in fact have it. It is incredible to know what happened now. It is hard to believe how much progress has been made in the past 50 years.
@alexshapiro9841
@alexshapiro9841 Год назад
The only thing hard here is your stupid brain
@UnpluggedAi
@UnpluggedAi Год назад
ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-SwNX2gSbgso.html
@Donotdisturb12441
@Donotdisturb12441 Год назад
I just love how to make it easy and explain each and everything (it's causes and treatment)
@nimishnandedkar9278
@nimishnandedkar9278 Год назад
Our body is so fascinating . Respect for my body is increased after this video ♥️🔥
@tphone6717
@tphone6717 Год назад
Not for the Maker?
@_emminowithoutl4995
@_emminowithoutl4995 Год назад
@@tphone6717 don't exist...(wait are u talking about parents?)
@tphone6717
@tphone6717 Год назад
@@_emminowithoutl4995 you have a surprise waiting
@outofthebox9699
@outofthebox9699 Год назад
Yeah and it just randomly evolved, just like Smart Phones.
@salmanwatto6214
@salmanwatto6214 Год назад
@@_emminowithoutl4995 what about the ultimate maker ( also of our parents )
@happinessallover
@happinessallover Год назад
Not a biology student but understood what these people explained.
@alexshapiro9841
@alexshapiro9841 Год назад
no you didn't, FOOL
@happinessallover
@happinessallover Год назад
@@alexshapiro9841 LMAO DED.
@monolinny1817
@monolinny1817 Год назад
@@alexshapiro9841 ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-RYDy_nlgi5Q.html
@lucienkennedy1997
@lucienkennedy1997 Год назад
@@alexshapiro9841 Stop gatekeeping
@bibaRU
@bibaRU 7 месяцев назад
​@@alexshapiro9841what is hard of getting it? If DNA isn't getting repaired cell becoming a cancel cell.
@ZenithalPoint
@ZenithalPoint Год назад
Everytime I see this sort of video, I feel like continuity of my existence as a lifeform itself is some kind of miracle and I could die any second in afterward
@mathewjoseph2237
@mathewjoseph2237 Год назад
This would have made high school biology class so much easier to understand.
@ttsuter87
@ttsuter87 2 месяца назад
Hopefully this type of learning helps further our understanding of these conplex topics. Visual learning is crucial for so many people.
@dr.devendrasharma6367
@dr.devendrasharma6367 Год назад
Simply Beautiful in every aspect, from science to animation.
@brukujinbrokujin7802
@brukujinbrokujin7802 Год назад
People dont realize that DNA is language of the Gods.
@MODEST500
@MODEST500 3 года назад
you aall are so good at ur JOBS damn !!! May God bless you and reward you for your work . stay safe .
@noble2694
@noble2694 Год назад
Man the animation is so sick and beautiful. Thank you very much.
@xinking2644
@xinking2644 2 месяца назад
I can't explain how useful these video are for me to understand this complex theory. thanks, million times!
@emperordrone1159
@emperordrone1159 Год назад
thankyou for being so much better than several other explaining this
@Nymus3D
@Nymus3D Год назад
You are so welcome! We do our best! :)
@WriterWriter4
@WriterWriter4 Год назад
I bear witness that there is no god but God, alone without partner.. Glory be to God and praise be to Him
@gibbogle
@gibbogle 15 часов назад
Tottaly stupid comment on a scientific video.
@computerheadman1601
@computerheadman1601 10 месяцев назад
The animation and explanation made it easy to understand, great vid 👍
@LoneFifteen
@LoneFifteen Год назад
All of this technological advancement, and my mom still died after being given the same treatment that they've been giving patients for fifty years. We need to push treatments like this to more people who need them and make them more wildly available.
@juliandiaz1457
@juliandiaz1457 9 месяцев назад
A todo el mundo
@toota1052
@toota1052 8 месяцев назад
😢
@OmBirajdar
@OmBirajdar 8 месяцев назад
Understanding biology by animation is genius
@noname8354
@noname8354 7 месяцев назад
Bro tysm for making this video. I'm going to be writing a literature review on PARPi and BRCA1 cancers so this video helped explain everything in a very simple way
@amiramiro8843
@amiramiro8843 Год назад
Thank you for that amazing and easy explanation of this ❤️❤️❤️❤️
@up5619
@up5619 Год назад
If this is an ad, it would be the type I would actually watch.
@lucienkennedy1997
@lucienkennedy1997 Год назад
Thank you so much for your work! Love it!
@marcelnowakowski945
@marcelnowakowski945 3 месяца назад
Absolutely fascinating! Thank you for this awesome animation!
@misskakouei6638
@misskakouei6638 Год назад
that was an amazing show, many thanks for your attempt to prepare it🙏💖
@thakursakshi_997
@thakursakshi_997 Год назад
Thanks for this beautiful explanation 💓
@PortableKonfidence
@PortableKonfidence 9 месяцев назад
Extremely clear and understandable. Thank you
@sahilraj2355
@sahilraj2355 Год назад
Bro why do you have only 11k subs you deserve 11 million.🥺
@colinmerritt7645
@colinmerritt7645 7 месяцев назад
Our bodies are amazing!
@Inspiration.U
@Inspiration.U Год назад
Very informative..learning in innovative way..really explained well in best ever experience..commendable and appreciable!!
@BamiAndCheese
@BamiAndCheese Год назад
I was actually busy studying on this EXACT subject for biology, so I appreciate this video *
@Algebrainiac
@Algebrainiac 23 дня назад
This is amazing! Props to the animators. Amazing explanation
@dairms
@dairms Год назад
Wow, this is absolutely fascinating.
@masoomshabir7221
@masoomshabir7221 Год назад
Love this video I'm happy knowing treatment for the deadly cancer. This is science of next level
@user-eg5cy8gt9x
@user-eg5cy8gt9x 3 месяца назад
This is really impressive, and as a biology student I now understand the diseases that might affect cells of DNA and the prevention process.
@ranjanasah5619
@ranjanasah5619 Год назад
The way of explaining this topic, is just amazing 🌼
@jyotigupta7821
@jyotigupta7821 Год назад
I loved the way of her explanation by 3D demantions
@jonayedrejaul7681
@jonayedrejaul7681 Год назад
That explanation is really great🥰
@-RightWay-
@-RightWay- Год назад
Thank you Most helpful video 👌🏼👌🏼👌🏼
@TrondHelm
@TrondHelm 3 года назад
Brilliant video, awe inspiring.
@Nymus3D
@Nymus3D 3 года назад
Thanks so much!
@mmd123king6
@mmd123king6 2 года назад
@@Nymus3D do they have a copy of the dna from the PCR or they just copy whatever was damaged from the dna?
@mmd123king6
@mmd123king6 2 года назад
@@Nymus3D thank you so much for making this veidio ❤❤❤
@fullentertainmentbyat4067
@fullentertainmentbyat4067 Год назад
ru-vid.comcD7vOkhYZpA?feature=share
@edenleave2054
@edenleave2054 Год назад
Wow this explained it better than my medical school
@XY-yg1ci
@XY-yg1ci 2 месяца назад
really helpful!!! better than textbooks
@Aviink
@Aviink Год назад
These calm me down for some reason and so do "How It's Made" vids.
@XavierAway
@XavierAway Год назад
Thank you for not dumbing it down
@rubiks.cube0008
@rubiks.cube0008 Год назад
Such designs so complicated and seem to be moving on its own with such delicate and amazing feats yet humans concludes that this is the result of random elements and dust clustering on its own with the help of time, lightning, heat and light is enough to produce such intricate work of arts.
@allenjiang7017
@allenjiang7017 3 месяца назад
As a science history and biology student (even though I have more lessons) this is amazing.
@raskolnikov1461
@raskolnikov1461 4 месяца назад
Sounds AMAZING
@ag-bk5wf
@ag-bk5wf Месяц назад
Amazing how the body works.
@INeedAPrenupSorry
@INeedAPrenupSorry 5 месяцев назад
Thats amazing how our bodies work like this
@brendataylor1467
@brendataylor1467 Год назад
Very well explained easy to understand Thank you .
@chynnadoll3277
@chynnadoll3277 Год назад
How great Thou art, indeed Heavenly Father❤❤❤❤❤❤
@geethar6090
@geethar6090 Год назад
This is amazing
@stanb1543
@stanb1543 Год назад
stellar graphics!
@bomberjoe3493
@bomberjoe3493 8 месяцев назад
Another lesson we can benefit
@autismunion
@autismunion 5 лет назад
Perfect!! God bless you
@Nymus3D
@Nymus3D 5 лет назад
Thank you Anwar!
@autismunion
@autismunion 2 года назад
@Imperial Terra it is just figure of speech, I dont believe in god either
@_emminowithoutl4995
@_emminowithoutl4995 Год назад
@@autismunion lol
@_emminowithoutl4995
@_emminowithoutl4995 Год назад
@@autismunion me neither brother
@gibbogle
@gibbogle 15 часов назад
Nutso.
@terryliu9015
@terryliu9015 Год назад
does anyone else find these things so fascinating? to me it feels like a fairy tale where everything just works out perfectly
@gibbogle
@gibbogle 14 часов назад
Not all the time. People are constantly dying of cancer.
@rkm17823
@rkm17823 Год назад
thank you for this information
@ashudhaliwal9524
@ashudhaliwal9524 Год назад
It's super amazing to understand the concept of biology ♥️❤️🥺❤️
@cibeleanjos3051
@cibeleanjos3051 3 месяца назад
Thank you for video I am student of nurse and these video animations help me of lot🙌
@Kh471D
@Kh471D 6 лет назад
amazing ! , thanks :-)
@torahama362
@torahama362 Год назад
Truly magical
@jasonvoorhees8899
@jasonvoorhees8899 Год назад
Please put such videos in a playlist.
@ExploringworldwithSWAT
@ExploringworldwithSWAT Год назад
Underrated channel 😔
@zoem491
@zoem491 3 месяца назад
The graphics are amazing 😮
@deeprollingriver52
@deeprollingriver52 10 месяцев назад
We should all be amazed and revere our bodies.
@deepsachin3951
@deepsachin3951 Год назад
Beautiful animation...
@user-sw9iq8tz7g
@user-sw9iq8tz7g 8 месяцев назад
Amazing
@realmenarzo7720
@realmenarzo7720 Год назад
Thank you 🙏
@foundingtitan7
@foundingtitan7 Год назад
The human body fascinates me ❤
@areebaaziz6796
@areebaaziz6796 Год назад
Now I come to know that how breast cancer arises and repaired you have explained very well
@ttsuter87
@ttsuter87 2 месяца назад
This is all amazing but how these proteins know that’s there job to repair DNA is amazing to me. How the is a subtle chemical process that causes this specific action is amazing. DNA is a wonder.
@strong_241
@strong_241 Месяц назад
Glory be to God, the best of creators ✨
@cks2020693
@cks2020693 Год назад
easily 10 hours' worth of grad-school medical knowledge explained in under 4 mins
@nirbhay_raghav
@nirbhay_raghav Год назад
Although it is not that simple as stated in the video, I loved the animation and narration.
@noname8354
@noname8354 7 месяцев назад
Ofc it's not that simple we're talking about biology here. That said, this is a very good summary of what happens and proves a great foundation for people to learn more if they want to
@vrindaaaggarwal4021
@vrindaaaggarwal4021 Год назад
Fascinating!
@ramrad5905
@ramrad5905 Год назад
Fantastic, that's awesome.
@joebarrett4353
@joebarrett4353 Год назад
Extraordinary
@Hannodb1961
@Hannodb1961 Год назад
How amazingly we were designed.
@gibbogle
@gibbogle 15 часов назад
We were not designed, don't be foolish.
@Hannodb1961
@Hannodb1961 14 часов назад
@@gibbogle Anyone who knows anything about the function of biochemistry, and believes that it all just created itself without a designing mind, believes in magic and has blind faith in the religion of materialism. Life were obviously designed.
@gibbogle
@gibbogle 13 часов назад
@@Hannodb1961 If anything is magic your god is. I do know a bit about biochemistry. Evolution is hard to understand, but supernatural non-material entities are impossible.
@letstalkourself
@letstalkourself Год назад
I love it what ur going to explain how magic is this i didn't understand this magic when I am in class
@user-lv1ir1kq4p
@user-lv1ir1kq4p 6 месяцев назад
Really just awesome❤
@rubiks6
@rubiks6 Год назад
You cannot tell me this is not designed by an incredible mind. The work of God is clearly seen here in the various DNA repair systems.
@morganh0421
@morganh0421 Год назад
These organisms are living quite an interesting life!
@p_p21
@p_p21 Год назад
Grt video during study I always use to assume that how these DNA break and repair through this animation now I understood that. 😁😘
@kjj26k
@kjj26k 2 месяца назад
The only thing more insane than the complex specificity of cellular biology is that we are able to, from our human scale, be that specific down there in the micro world.
@lt4128
@lt4128 Год назад
Excellent voice🇮🇳 👍 and music 👍
@asanablue
@asanablue Год назад
Excellent video.
@alokmurmu7682
@alokmurmu7682 5 месяцев назад
Damn that's amazing 😮
@amorakareem8072
@amorakareem8072 Год назад
Thank you very much
@tamilshortfilm6070
@tamilshortfilm6070 Год назад
Best video 🙏
@upendarkumar-on9ks
@upendarkumar-on9ks 19 дней назад
Background music.. exited..❤️
@Video-oc7pj
@Video-oc7pj Год назад
Thank for information
@sudhadhanam3711
@sudhadhanam3711 Год назад
Thx for easy technology method 🙏
@WitmanClan
@WitmanClan Год назад
Thank you 🙏🧬🙏
@4kstatusss
@4kstatusss Год назад
Well explained
@Heroesflorian
@Heroesflorian Год назад
I can't help but think that explanation is missing a crucial part. It says some patients lacking double strand break repair functionality due to their inheritance is what causes the cancer, but then proceeds to state that the ability to repair double strand breaks is what prevents all the non-cancer cells from dying as well. Without additional information, those two statements feel a bit contradictory to each other: An issue caused by the inherited lack of an ability is fixed based on trusting in the very same ability the lack of which caused the issue, and killing anything with a lack of that ability.
@gta5noobgamer218
@gta5noobgamer218 Год назад
Does this work for all types of cancer? If their is a lot of tumour cells can they not be healed? Great video.
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