I think the fact that Strong Sad wouldn't let the evidence be analyzed confirms that he really is part elephant or hippo, or at least he isn't very confident that he isn't.
The fact that Homestar's trench coat sleeve rises up when he drinks the DNA evidence makes me question the entire nature of the arms of him, Homsar, Marzipan, and the King of Town.
*Cinemasins voice* The DNA in the glass has greater volume than the DNA in the paper cone. Even though the ice melted, water has more volume when it is frozen. And if it melted as Strong Bad walked home then how did it all stay in the cone?
I remember when this first came out and I was very disappointed. it would have been so much funnier if they never addressed the DNA evidence. just have them be a running joke throughout the entire series. you didn't need this cartoon.