DNA Testing and Privacy (Behind the scenes at the 23andMe Lab) - Smarter Every Day 176

Подписаться 12 млн

Просмотров 1,5 млн

50% 1

If you want your own personalized DNA genotype data here's the link: www.23andme.com/smarter
Click here if you're interested in subscribing: bit.ly/Subscribe2SED
⇊ Click below for more links! ⇊
A super big thank you to all Patrons of Smarter Every Day:
Smarter Every Day on Patreon
/ smartereveryday
~~~~~~~~~~~~~~~~~~~~~~~~~~~~
GET SMARTER SECTION
A special thanks to Dr. Neil Lamb at the Hudson Alpha Institute for Biotechnology. A major mission of Hudson Alpha is to educate the public and promote genomics literacy. I talked to many scientists about Genotyping but Dr. Lamb's ability to break down the complexity of the human genome is what finally brought it home for me. Hudson Alpha provides many opportunities for Genomics Education and
Hudson Alpha is hudsonalpha.org/ for explaining the difference between Genotyping and Sequencing. To contact a super smart Genomics Professional at Hudson Alpha click here: hudsonalpha.org/contact
Genotyping and Sequencing are very different:
en.wikipedia.org/wiki/Genotyping
en.wikipedia.org/wiki/Sequenc...
The 23andMe Genotyping service is provided by LabCorp
According to their website, LabCorp is "The World's Leading Health Care Diagnostics Company"
www.labcorp.com/
No Private or Health Information about any individual was recorded or shared in the making of this video (This video is HIPAA compliant).
A special thanks to the Lab Manager Amanda Douglas for being a complete science rock star and a great person to work with I spoke with about a dozen LabCorp Employees who are under Amanda and every one said she was an absolute joy to work for. I know my experience working with her great and I hope her boss reads this blurb I wrote down here in the video description and gives her a high five and a big fat bonus or something equally as awesome.
23andMe provide Genotyping testing using an Illumina HumanOmniExpress-24 format chip. Here's a bit about the chip. Heads up, it's incredible technology. • Illumina Infinium Assa...
~~~~~~~~~~~~~~~~~~~~~~~~~~~~
GET STUFF SECTION:
(If I did this right these should be working Amazon affiliate links to purchase the stuff I like to use. When people purchase from these links it will support Smarter Every Day.)
❓Mystery Item (just for fun): amzn.to/3cX2id4
Things I use and like:
📷Camera I use : amzn.to/2VSiruw
Favorite Lens: amzn.to/2KPDQ1a
Wide-angle: amzn.to/2SlPchR
On-camera Mic: amzn.to/2SJulF4
Lav Mic: amzn.to/3aRek6r
Hot shoe mount for Lav Receiver: amzn.to/35m6uAo
My Tripod: amzn.to/2Yl6RtJ
My Multi-tool: amzn.to/2zGm5Pz
Favorite SD Card: amzn.to/2KQ3Edz
💾How I get footage off my phone: amzn.to/2KMem4K
Travel Tripod: amzn.to/2zEa9Oi
My Backpack: amzn.to/35jveJL
My Headlamp: amzn.to/3deYmVt
Favorite Bidet: amzn.to/2xnMG3b
World Map: amzn.to/3aTFCZT
Favorite Shoes: amzn.to/3f5trfV
Everyone needs a snatchblock: amzn.to/2DMR4s8
🥽Goggle Up! : amzn.to/2zG754g
Also, if you’re interested in a Smarter Every Day shirt etc. they’re really soft and you can get there here: www.smartereveryday.com/store
~~~~~~~~~~~~~~~~~~~~~~~~~~
Tweet Ideas to me at:
/ smartereveryday
I'm "ilikerockets" on Snapchat.
Snap Code: i.imgur.com/7DGfEpR.png
Smarter Every Day on Facebook
/ smartereveryday
Smarter Every Day on Patreon
/ smartereveryday
Smarter Every Day On Instagram
/ smartereveryday
Smarter Every Day SubReddit
/ smartereveryday
Ambiance and musicy things by: Gordon McGladdery did the outro music the video.
ashellinthepit.bandcamp.com/
The thought is it my efforts making videos will help educate the world as a whole, and one day generate enough revenue to pay for my kids college education. Until then if you appreciate what you've learned in this video and the effort that went in to it, please SHARE THE VIDEO!
If you REALLY liked it, feel free to pitch a few dollars Smarter Every Day by becoming a Patron.
/ smartereveryday
Warm Regards,
Destin

Наука

Опубликовано:

7 июн 2024

Ссылка:

Скачать:

Готовим ссылку...

Добавить в:

Мой плейлист

Посмотреть позже

Комментарии : 4,1 тыс.

@MrWynterpaladin 6 лет назад

When the guy says, "Welcome to the Institute" I got Fallout 4 flashbacks.

@NessieAndrew 5 лет назад

Yep.

@dirtyweapons3459 5 лет назад

I found the comment I've been searching for

@PCLHH 5 лет назад

YEEEEESSSSS!!!

@spartanclucky884 5 лет назад

YESSS THANKYOU!!!!!! Is it ironic he looks like a groomed version of SHAUN?

@Zimited 5 лет назад

Reminds me of Voyboy's cringy subscriber notification on stream

@j23eagle 6 лет назад

8:13 - Destin says, "This is like from the future!" 8:17 - Uses Windows XP...

@HmmContemplates 6 лет назад

Haha, I just was about to comment the same thing

@yipperdeyip 6 лет назад

Yeah... Imagine them using Windows 10... Literally EVERYTHING said about privacy in this video would be completely irrelevant.

@Jacksirrom 6 лет назад

Windows XP is radically less secure than Windows 10. It's so outdated it's almost laughable that this company is trusting the genetic information of its customers to that OS. It should honestly be criminal or a violation of HIPAA medical privacy and security rules.

@J4K_Shred 6 лет назад

j23eagle i want a macbook... and instqll windows

@nibblrrr7124 6 лет назад

+Jacksirrom AFAIU the problem is that specialized biomedical software or drivers for the super-expensive equipment are often no longer updated to be compatible with a newer OS. "Never change a running system" is bad for security but often the only affordable choice. I'd guess that criminalizing the users first is probably a bad approach (it'd basically allow manufacturers to charge horrendous sums for new updates). My bet would be on creating data I/O and format standards in the industry (cf. "plug &play" USB drives, monitors, keyboards...), or forcing a company to release the source code when they stop releasing updates?

@jchrizzy6995 3 года назад

That elbow bump was further evidence that Destin is an omniscient being, with knowledge of future events

@Astilath 2 года назад

Sterile 5 (air high 5) or (foot) low 5 or elbow bump has been standard lab practice (in cool labs) for decades. 😁

@jaredkinneyjr 2 года назад

I will NOT help China develop a genetic bio weapon to kill everyone but Chinese dna. Obviously the genetic data goes somewhere... C'mon if your that naïve

@jaredkinneyjr 2 года назад

Oh wait, nevermind. Corona testing already did that....🤔(Los Angeles Sheriff press conference)

@gabgornitzky2716 4 года назад

I’m sorry. I just find it really ironic that one of the biggest dna testing facilities is in Alabama.

@samvanders1235 4 года назад

10/10 comedy

@groggysword33 4 года назад

Caz L Orrell haha... “sister” facility.

@mangokraken 4 года назад

this is peak comedy

@stevengolden689 3 года назад

@Cal Vert are you defending incest in the youtube comments right now?

@azzam451 3 года назад

Hahahahahaha, nice joke

@Norse_Code1 5 лет назад

"Welcome to the institute"....Wait a minute ive heard this before

@VanityStar00 4 года назад

The second i heard those words i was like ohhhh here we go

@smokebullet8044 4 года назад

payrim Dwein SHAUN. SHAUUUN. SHAUN. SHAUN. SHAUN. WHERE IS SHAUN. I NEED SHAUN. SHAUUUN. SHAUN. GIVE ME SHAUN. I REQUIRE SHAUN.

@toriancromar 4 года назад

😂

@davidblanchard66 4 года назад

This is an iconic comment.

@djsj6798 3 года назад

Man that's just Scarry!!!!!?????

@Tetzuoe 6 лет назад

I love the LED accents on the sequencing machine. Like, you didn't have to... but it's a million dollar machine and you went that little bit out of your way to make it look futuristic and sciencey.

@NandR 6 лет назад

That's exactly what I thought. The machine looks very well designed because of that.

@euttdsiggh2783 6 лет назад

James Congdon dude, same

@Twisted_Sync 6 лет назад

I had the same thought, it's totally worth it

@FAB1150 6 лет назад

Why did I think the same thing lol

@jackmarshall5026 6 лет назад

yeah and i like the Windows XP machine plugged into the Genotyping machine at 8:27, no extra money spent there

@loungingcat 2 года назад

Got a kit, but the privacy concern is still nagging at me so I started to search for reviews and came across this, among other videos. This video actually made me really hesitant about consenting and sending my saliva in. Questions were softball and Destin went in like he's already part of the 23andme team, like he's there to debunk all your concerns, and not to find out if there is anything you should be concerned about. Many people brought up the fact that you actually gave them your entire DNA, but they're the one that chose not to use the entire thing. Destin showed how the saliva samples are tossed but not the digital info that they already logged in. He said Tara went and spoke with different researchers and professors all over the country and discussed the benefits and risks of doing this type of testing both on the individual level and its overall implications for society... but all that's shown in the video is her key takeaway, that optional questions are the key for scientists to find out what genotypes affect what traits, and they, as a family, want to contribute to the body of knowledge (5:41). At 12:49 she said she feels the benefits outweighs the risks (did not explain what the risks are), and that the information is helpful for the society as a whole as well as the individual. I feel like Tara's part is very weak, no actual discussion with researchers were shown, basically we'll just have to take her word for it. No wonder he had to say he didn't take money for this, because this does look like an ad for 23andme.

@reinhardt3090 Год назад

I felt the same way about the video. Really made me question the rest of his content.

@TornacenseDeFuturo 5 лет назад

7:05 it's nice how you put those uniforms and then a delivery guy just enter with normal clothes ;)

@AS--999 6 лет назад

I've got a BSc in Genetics so thought I'd explain a bit more on how significant that small percentage of DNA they take is and also add some extra interesting facts, including why we're still not really using genetics much in medicine (which I believe ties into the third party scientists mention of the "nuances of human genetics"). :) Firstly, while I'm not paranoid about it, what they mentioned on genotyping and how little info they take - that small percentage is actually not as safe and insignificant as you might imagine. This is because the vast majority of your DNA is made of repetitive "non-coding" sequences. As an example one single type of repetitive sequence, called the ALU sequence, makes up about 10% of your DNA - this is more than all the "coding" elements put together! When you look at how much of your DNA is coding data it's actually a very small amount, so they'd actually be collecting a substantial amount of info on what makes you uniquely you, and this *could* still be used to identify you! While I say this though, the interesting fact is that in things like paternity tests, they actually don't use any coding data! They use the pattern of the non-coding elements - so in a paternity test they ironically identify the father from DNA that doesn't specifically code for the father or the child! You may be wondering why there's so much non-coding DNA - interestingly they used to call this "junk DNA" as they knew it didn't make proteins and thought it was waste left over from evolution. They actually used to remove this on early cloned animals, but through that they realised it's not actually "junk" (if you look up Dolly the sheep, one reason she actually got really ill because they removed her "junk" DNA). This is actually used - amongst other things - to promote/inhibit/control what parts of the genome are expressed. This is known as epigenetics (which also has a lot of other areas, not just this - it's truly fascinating!), and that's one of the new big areas of genetic research. With epigenetics, we now know that even the coding parts don't specifically code for who you are as there are further controls and some of it is never even used! That is why for most genes they don't say "You have X gene so you'll get X illness" - they only say a % as your body may or may not use those genes in ways that cause that illness. ...also this is different for every cell in the body as they're all pretty much independent. If you want to read anything even more fascinating you should look into the human microbiome - which is how they actually think the DNA of organisms inhabiting out body could have even more impact on things like health than our own genome through (genetic) symbiosis! The total bacteria inside you have potentially 100s of times more genetics data that you do, so if there is symbiosis there you can get how relevant that is - essentially they're an extension of your genome! ...worth remembering that next time you're prescribed a broad spectrum antibiotic (which basically aims to kill all internal bacteria!!). With epigenetics and the human microbiome though, hopefully that shows why so little genetic info is still used in medicine and diagnostics. DNA is not the simple blueprint of life we thought it was 20-30 years ago, so it's not a straight tool that can be used for diagnosis - it more shows you potentially how healthy or sick you *could* be, rather than what you *will* be.

@wildmangrove3096 6 лет назад

Tad Springer Dolly the sheep became ill because the chromosomes of origen became from an adult sheep. That means shorten telomeres.

@AS--999 6 лет назад

Carlos Alemán Dyer while that's true, it's not affected other clones that have also been cloned from adult cells as now they include non coding regions. The exclusion of non coding regions meant there was less control of gene expression, which led to extreme levels of inflammation. That's why Dolly had extreme arthritis by the time she was about 2. A far as the shortened telomeres, there's an enzyme called telomerase that extends these. This means it wouldn't have passed to Dolly. The cells that were chosen were also taken from a fairly young sheep and were compared to many others to choose cells that hadn't lost much genetic information from telomeric shortening, so it's unlikely it played a huge role in her illness. It's all relative though so it could have still contributed.

@wildmangrove3096 6 лет назад

Tad Springer I'm not inventing stuff up you can do a research and find that they where studies on telomere and telomerase as early 1994, but the activation of the telomerase was not use in Dolly. Activation, because the telomerase is inactive in mammals. For Dolly they not only clone 1 sheep but 3 and compared the length of the telomeres between them, 2 of them were the same and1 was different because the age difference of the donnor. So yes the fact that Dolly age quickly and had health problems is because of the shorter telomeres (Here is a simple bibliography: Blasco, M et al.; Telomere and telomerase; Genes and development 1999, 13 Xu J., Yang, X; Will cloned animals suffer premature aging - The story at the end of clone chromosomes; Reproductive biology and Endocrinology; 1; 105; 2003 Shiels P. Et al; Analysis of telomere length in Dolly, a sheep derived by nuclear transfer; Cloning; 1(2),2004; 119-125)

@AS--999 6 лет назад

wild mangrove I'll have to check those out, but telomerase definitely isn't inactive in mammals.

@Andytlp 6 лет назад

So never use antibiotics unless youre already dying? Tell me something i dont know. I like my microbiome old and healthy. No drugs for me thanks.

@ahmedm6228 6 лет назад

8:12 _"This is like from the future"_ . Three seconds later.. 8:15 Windows XP running in the background 😂😂😅

@williamgarcia1417 6 лет назад

Ahmed M IMO Windows Xp and 7 were the last good Windows

@DaxenGaming 6 лет назад

That's not Windows XP, that's Vista.

@meizpru2559 6 лет назад

William Garcia but not good for gaming and editing ;)

@thereaper2615 6 лет назад

Me iz pru depends on what game you wanna play. Newer games, not So much. But older games run wonders in these OS.

@meizpru2559 6 лет назад

Weedle Guy what's the point ? you can play old games on newer windows, and .. oh cmon who still play old games ? newer is better baby

@ModernBladesmith 4 года назад

Neal: "welcome to the institute" Destin: WHERE IS MY SON!?

@ela489 4 года назад

I think we are the only people who understand that 😂😂

@jimmyshrimbe9361 5 лет назад

This is awesome! It makes me want to contact these specific companies and let them know how thankful I am for them being so transparent! It’s such an important thing!

@Phoboskomboa 6 лет назад

The reason they only need 0.02% of your DNA is because that's the stuff that varies from human to human. All humans share 99.98% identical DNA. The reason they only work with that 0.02% is just for minimizing file sizes by focusing only on the variable parts. That 0.02% contains all the relevant information anyone with sufficient technology would need to know everything about your genetics. It's just a matter of file formatting. It's like if you're giving directions to someone. You don't give every single turn along the way. You just say "you know how to get downtown from here? Okay. Do that, but take a left instead of a right on Sycamore." Or "you know what a generic reference human genome looks like? Okay, do that, but these 600,000 sites are different."

@arcadiomushi1955 5 лет назад

Thanks for complicating.

@funposting8912 5 лет назад

I'm tempted to get a full genome sequence (Well, I've wanted to for ages), then get a genotype done, and see how close I can get to my original genome by merging the genotype with a random human genome downloaded online.

@funposting8912 5 лет назад

@@arcadiomushi1955 Basically the idea is that if you did a full sequence on 1000 people, they'd all share nearly all of their genes (99.98%). If you take the stuff that's identical in all of them, you could call that the human template. All you need to go from a totally generic, human template, to you, is that extra 0.02% that 23&me collects, called your genotype. If I had a copy of your genotype, even though it's only 0.02% of your full DNA, (and some other random human's genome) I could recreate near perfectly 100% of your dna. A puzzle with a million pieces, and there's only one piece that's different from each human. You have that one piece, that's enough.

@axela.9247 5 лет назад

@@funposting8912 the best explanation ive read

@funposting8912 5 лет назад

@@axela.9247 Glad I can help.

@xKarma_411 6 лет назад

"you're hiding this samples afterwards huh" Amanda: *His on to us*

@tammywerner6442 6 лет назад

xKarma _ "his on to us" what about his on to us?

@jackc3727 6 лет назад

Sam Werner He made a mistake, grow up.

@dennissolodovnik2168 6 лет назад

He's*

@xKarma_411 6 лет назад

As much as I appreciate your support *Jack C* , sadly I have to face judgement and exile for my typo, farewell old friend. *Fades Away*

@naota3k 6 лет назад

Your 'e' and 'a' were mixed up with your 'i'.

@gavinhooker7917 3 года назад

A huge thank you Destin for taking the time and effort to making these videos. Thank you

@madeintexas3d442 3 года назад

I love this. I have questioned creators who have been sponsored by 23 and me but also were in support of individual privacy. Great video and great subject matter. Can't believe this is 3 years old and I'm just seeing this I've been subbed for awhile.

@NBFman1991 6 лет назад

2:25 - "Welcome to the Institute." Destin better watch out for the synths

@canofspam4337 6 лет назад

That name tho

@AngryBulldogGaming 6 лет назад

those Synths are everywhere. how do we know that scientists is a human? she looks suspicious. -_-

@Dzeroed 6 лет назад

lmao, nice.

@isakhedberg7561 6 лет назад

I thought the exact same thing, and went to the comments hoping somebody else did

@TheMixflow 6 лет назад

scrolled down just looking for this! made my day hahahah

@LiftPizzas 6 лет назад

I like how people act as if spitting in a tube is the only way your dna would ever leave your body or be easily accessible to someone who wants to collect samples.

@Dogman690 6 лет назад

Lift Pizzas and they act like people can just "create a virus to kill only you" because they don't understand dna. What these companies do it look at your genes, they can't just change your dna to make some virus. The closest thing we have to gene modification isn't even 100% accurate at all and will take YEARS to be even close to what we want from it. People need to stop fearmongering others and grow up

@dykam 6 лет назад

While you're right that if someone wants to target you specifically, they can get a sample with a fairly good chance of no contamination. But realize 23andme also asks a ton of questions, and is a bigger target for large scale DNA profiling (insurance rates, etc). Not saying it will happen, but be aware it's not the same.

@bobbym3155 6 лет назад

Lift Pizzas in big data business the real challenge is sourcing large volumes of clean, labelled, structured data. So while random dna is everywhere, carefully collected, labelled dna samples are not. People submitting their dna to companies like this gives them the massive opportunity to mine and resell that data.

@MK-ex4pb 6 лет назад

Lift Pizzas because it makes it a lot easier than scraping off a toilet seat or leftovers

@TheRmbomo 6 лет назад

_PhilfreezeCH_ I believe Turdeau was saying blacks, mexicans, and arabs are genetically predisposed to having an IQ below 100. As a sort of trend. They were not saying without a doubt ALL surely do.

@misakamikoto8785 5 лет назад

don't forget the privacy term will always include the following term: UNLESS REQUIRED BY LAW.

@weirdworld3874 4 года назад

People often forget this fact. The U.S government will bully any company into giving them your information if that company wants to stay in the good graces of good old capitilism.

@philipwebb960 4 года назад

So you shouldn't let yourself be put on the grid in any form, since courts can order disclosure of ANY information. Have fun living in a cabin in the woods without electricity, bank account, auto, job, internet, etc.

@weirdworld3874 4 года назад

Philip Webb Ha, you seem to be the one paranoid. Never once did I mention not to sign up for anything as that would be impossible. I merely pointed out that fact. If you have nothing to hide right.... I'm all for civil conversation but one of my pet peeves is having to argue a point I didn't make. I hope I cleared this up for you. Have a great life.

@robertunderwood1011 4 года назад

@@weirdworld3874 OR, you can enjoy the other option which is to ignore the fact that undetected murderers are walking among us that could be arrested. Which do you choose to sacrifice: your privacy or your safety.

@theonlyairconditioner 3 года назад

It also includes that they can change their privacy policy at any time they want.

@Tman896 5 лет назад

Super awesome of 23 and me to work with you on!! That’s really reassuring!! Despite you not being a journalist or news outlet it’s people like you who are truly doing real investigations of things and letting the public know! Thank you so much!!

@smartereveryday 6 лет назад

I was concerned about what actually happens with my genetic information when submitted to 23andMe, so when they approached me and asked me if I wanted to make a video I decided to investigate it top to bottom. Visiting the Lab and learning that their data is contractually isolated from the sample and the fact that it's not the entire DNA sequence being sent to 23andMe headquarters passed my smell test and satisfied my privacy concerns. My wife spoke with professors and industry leaders from around the country and learned about the benefits of a future of medicine based on genomics. My wife, Dr. Lamb, and 23andMe all independently stressed the importance of understanding exactly what the results of the health genotype testing mean by consulting your (well informed) doctor. In a nutshell, the results don't provide deterministic results, but a probablistic indicator based on historical data. Many other factors play a huge role in how your body works.

@slikrx 6 лет назад

My biggest concern with 23 & Me and the others, is that they refuse to give "forever" privacy on your data. This is made worse by the fact that they won't let you submit DNA "anonymously". (ie, we give them money and a return address, that's all) The issue here is that insurance and or anyone else has access to the IMPORTANT gene sequences. Things like genetic propensity of your genes for things like cardiac problems, Alzheimer's, etc. You know, things that cost insurance companies money, and make you a bad insurance risk. YEs, they don't share the info NOW, but they refuse to put "forever" in the privacy policy.

@unlokia 6 лет назад

Gosh, Amanda is *beautiful* and SO NICE. Not related to DNA, but related to fact :)

@smartereveryday 6 лет назад

With respect, you're wrong on every point. You can achieve the "forever" condition by choosing to destroy your sample and the data. I investigated every concern you just brought up (because they were also my concerns) and checked out every counterpoint and validated each one either with my own eyes or a third party. You can delete the data and I saw samples destroyed with my own eyes. You also don't have to provide a return address. Insurance doesn't have access to the data, in fact there are several laws about this. EDIT: 23andMe read this comment and asked me to add this clarification: You can have your sample discarded after a 6 month processing time. Your account can be closed, at which point your information will be removed from your account, but some information may need to be retained to comply with lab quality regulations, such as CLIA.

@smartereveryday 6 лет назад

You're wrong.

@smartereveryday 6 лет назад

She's super smart as well.

@repomandan07 6 лет назад

The Privacy issue is with the collected data not the discarded sample. What does 23andMe do with the collected data do they sell it share it do more research? Does the government have access to this information.

@AtlantideVFX 6 лет назад

Why would the government would be interested in your possible predisposition to illnesses, or racial history?

@JimPekarek 6 лет назад

The big concern here is less the government and more health insurance companies. I can imagine they'd love to start increasing rates or denying coverage for people based on genetic predisposition for certain diseases. And I don't exactly trust the people in Congress and the White House to make sane, well-informed decisions with regards to legal issues like that.

@apgeneticgenealogylover6601 6 лет назад

The privacy concern is overblown for many reasons.

@ChrisDuncanCodeCow 6 лет назад

List some please.

@thereaper2615 6 лет назад

Eric M Yeah, agreed. If you have more risk you should pay more, It's like that in everything in life.

@tigerlilly1430 4 года назад

I absolutely love smartereveryday. You have an awesome way of breaking down complex questions with simple answers. Always excited to watch new videos because I knew I will learn something new and exciting every time.. making me Smarter Every Day!

@justinpowell534 2 года назад

Being someone who is approaching their final year of an undergrad genetics degree this is like the absolute thing ever! Being able to see the theory and basics I've been learning actually applied in the real world. Thank you so much for the amazing content and making me smarter every day! Greetings from South Africa

@BobWidlefish 6 лет назад

At which step does the CIA get a copy?

@joyjoyoo 6 лет назад

BobWidlefish the very beginning

@Trident_Euclid 6 лет назад

BobWidlefish As soon as it leaves your house.

@TacNaynMC 6 лет назад

Why do they need another copy?

@GoodraGirly 6 лет назад

They already took scrapes from your tinfoil hat. :)

@draygoes 6 лет назад

Remember that time when you first diddled yourself? Right after that.

@amyhull754 6 лет назад

Tara, thank you for being willing to be on camera to share this, and for your important points. Both my husband and I are adopted, and I am planning to do the genotyping for both us and our two kids because we are lacking even the family stories that might give us hints. (So...at least we don't have to decide whether to share with our wider families!) Destin, thank you for asking them for the concessions you did, for getting a 3rd party to discuss the details of the system, and for making this video to share with us all. It is really nice to have more information about a company I'm planning to use sometime this year.

@roxannefranco7052 2 года назад

This is the best video i've seen on this matter tbh. Great investigation and explanation from you and your wife as well as all the people in the lab. Thanks to everyone!

@tHustr4 5 лет назад

2:25 "Welcome to the Institute" *Destin is a synth!!*

@dureemarie 6 лет назад

What is done with the digital information gathered by 23&Me and the labs? They trash the samples when people don't want them to be stored, but they've read the DNA already and stored that information digitally, I'm sure. Is that also destroyed?

@NessieAndrew 5 лет назад

Who knows... :)

@vjm3 5 лет назад

I would try reading the 23andMe privacy guidelines. I bet somewhere there's something that says "This information, if you choose to have it destroyed, will not only be physically destroyed, but our system will also delete this information after X amount of days/years." I mean, I can't imagine they'd be able to afford saving all that data on their servers for too long.

@MrMissionkid 5 лет назад

@@vjm3 well... This is genotyping so it's looking at .02% of the genome, and the full genome on the other system was about 80GB... If my head math is correct that would make the multiplication come to .016GB but even then that's too much because each of those 600,000 genes was simplified by reading off a binary Gene type from the final base pair. In the end they wound up with 600,000 bits of information, which would make for a miniscule file size. I'd say that this falls into the category of so little file space it costs less to keep it forever than to deal with the logistics of knowing whether to get rid of it or not. People are forgetting they have to save the data so you can access it...

@supersat 6 лет назад

Unfortunately, there's still some uncertainty around the legal implications of knowing various genetic testing results. To their credit, they clearly outline the risks in their Terms of Service: "While the Genetic Information Nondiscrimination Act was signed into law in the United States in 2008, its protection against discrimination by employers and health insurance companies for employment and coverage issues has not been clearly established. In addition, GINA does not cover life, long-term care, or disability insurance providers." ... "If you are asked by an insurance company whether you have learned Genetic Information about health conditions and you do not disclose this to them, this may be considered to be fraud." Yikes! It's also unclear how much information they associate with your account. They definitely ask for your full name and date of birth, although I suppose you do not have to provide real details. I do wonder if they store the address a particular barcoded tube was shipped to, which is harder to conceal if you are concerned about your privacy. They do sell kits in stores, but you still have to pay a separate lab fee through their website when you submit your sample, making it hard to have a truly anonymous 23andme account. The bit about .02% of your DNA being analyzed is a bit misleading. If you go back and look at that bookshelf, there is a binder labelled "exome," which contains only the coding regions of DNA, and accounts for about 1% of human DNA. 0.02% is still a lot smaller than 1%, but the vast majority of your DNA is identical to others (even other animals), so a relatively small number of SNPs could tell you a lot about a person. I am also curious about what kind of data they give you if you are truly curious. The FDA has finally allowed them to disclose some health information, but there are certain categories of health information that they cannot give out. However, I have heard that you can download the raw SNP data and interpret the results yourself?

@gwenc1371 6 лет назад

"Yikes!" Yikes indeed. This is one of multiple reasons why, for the time being, my doctors and I have agreed that not pursuing a confirmation of Ehlers-Danlos with a geneticist, and keeping it off my files, is the best route to go. There are some clinical reasons as well(treatment & monitoring isn't affected, ignorance by healthcare professionals makes it borderline-useless anyway, etc), but the concern that I may be screwed in areas like life insurance or future holes that get poked in federal protections is definitely one of the bigger reasons that have come up. It's really sad that issues like this alter the clinical suggestions of medical professionals, and that we have to tip-toe around it until it becomes absolutely necessary to be recorded on paper.

@Jooonathan 6 лет назад

Why would you be obligated to disclose such information to them if you have it?

@Kyru988 6 лет назад

Gwen C HIPPA gives you the right to with-hold this info. Even in records, I work in a medical facility; for Labcorps in fact (once PAML) and some of that data is retricted depending on what it is. We have three sections that I can come to a conclusion with. The insurance company, the billing provider and the medical facility where the doctor is.

@Corn0nTheCobb 5 лет назад

@@Jooonathan Because, like he said, it could be considered fraud if you don't.

@jssherrard 6 лет назад

This was super interesting and I'm now excitedly waiting for my 23andMe results! Thank you for the behind the scenes look at the process.

@mrpirate3470 5 лет назад

I literally poated my sample off to 23 and Me an hour before this video landed :) I was adopted from birth and have absolutely no idea about my heritage or any genetic predispisotions. I'm looking forward to the results. Now finally I can answer my doctors questions ''do you have a history of xyzabc in your family'', and finally I can have an idea about my genetic roots and where I'm from.

@MrRicmeme 6 лет назад

They should have said something like "you're only giving a really small part of your entire DNA, ***however the part they take represents the most unique parts of your DNA, which is why they take those***". The privacy concerns are very much relevant and the argument used to reject those concerns - it's just a tiny bit of your DNA! - is not valid.

@ObjectsInMotion 6 лет назад

It does completely wreck the cloning argument. You can't make a clone with only 600,000 base pairs.

@chasevogler543 6 лет назад

Anthony Khodanian yes, but the other 99.998% of your DNA is pretty much the same as all other humans, so if they had the technology to clone someone from a complete genome, they could probably clone you from that little bit of your unique DNA combined with the rest of the DNA shared with all other humans

@tjc9514 6 лет назад

There are 3 million differences between human genomes and according to Destin's video, 23&Me tests for 697615 markers which is still only about 23.25% of your unique genetic makeup. So this argument isn't entirely valid

@jackfiercetree5205 5 лет назад

@@tjc9514 you do know how well computers play chess now?? They could easily model the rest.

@tjc9514 5 лет назад

@@jackfiercetree5205 sure you could iteratively go through every possible combination but it would be extremely prohibitive, even with advanced chess playing AI

@vikio452 6 лет назад

Jeez, that lab is staffed by beautiful people! You sure it wasn't a movie set, Destin?

@satibel 6 лет назад

What? Beautiful people in science? Unbelievable! 100% sure those are actually robots.

@grantbaugh2773 6 лет назад

They got the same people that did the moon landing.

@jamiehatchell4070 5 лет назад

I bought it about 2 months ago. I feel confident now that I saw this video. Many thanks to the both of you.

@sweetheartokay69 5 лет назад

What if I send the sample back with the spit of my dog and then some random results come back 😂🐕

@Le0nder 4 года назад

Question is: Will you be able to handle the results? :D

@3ffrige 4 года назад

I don’t think it’s from the same company, but they have similar programs for dogs where you swab the inside of their mouths and get back valuable information regarding their breed, health characteristics, etc. Personally, I wouldn’t want to spend $200 on a kit just to put a sample from my dog just to have all the lab guys be like WTF. Or maybe I would. What if I’m part poodle?

@Hilko26 4 года назад

I would love it if someone did that and shared the results

@Ryan_Richter 4 года назад

A lot of the primers they use in these assays are human-specific, so from the results you'd get a lot of null responses, and they'd likely conclude that there was something wrong with the sample. This is why you can send them spit that also contains the genomes of thousands of different species of bacteria in your mouth without getting bad data.

@nishantjain7051 4 года назад

Nice

@ismaeelabuabdallah4866 6 лет назад

Not to be paranoid, but just to be more clear: You are giving WHOLE of your genome, but they say that they use only specific parts (0.02%?) of it. Please correct me if I am wrong, @SmarterEveryDay

@drakan4769 6 лет назад

the method they're using only reads for specific parts, it takes an entirely different method (video implies a far more complex and costly one) to map the whole thing

@SpOmLoL 6 лет назад

they do not have the equipment to analyze your whole genome, for that they need machines like you saw in the beginning

@ismaeelabuabdallah4866 6 лет назад

I do understand that. But there are two things: - For specific people, they may send the sample to another lab. - I do not think the visit was a surprise visit.It seemed like a planned one. Understandable, but ...

@SpOmLoL 6 лет назад

I'm actually studying for laborant, and I can tell you, the samples you get are just labeled with the barcode, you don't get to see any names. also this only requires your email address. you don't have to say your name. the way they work in the video is actually how the work is in real life. so yes this may be a planned visit, but on the other hand I can confirm this is the daily way of handling stuff at the lab.

@drakan4769 6 лет назад

" For specific people, they may send the sample to another lab." The lab that does the testing doesn't have information of which sample belongs to who, as he said, the lab has a number and a sample, while 23andme has a number and an email

@TheCornflake01 6 лет назад

you had the opportunity to ask every question and you did not ask one really critical or scectical thing. thats just normal advertising

@zebbleganubi723 6 лет назад

he made a joke that they dont actually throw away the samples afterwards but that was it unfortunately. either he is getting paid a ton for this or he is just clueless on the real privacy issues that are at stake

@joshG1513 5 лет назад

what questions would you have asked?

@Chicken56877 5 лет назад

joshGerbwrecked I think if possible we can start by referring to their terms and conditions. Like whether or not they will give the information to the government if the government told them to.

@matthewjackson9615 5 лет назад

Looks like I'm not the only one that observed this. That's right he' just advertising for 23 & me and getting a piece of the advertising dollars.

@SchmCycles 5 лет назад

@@joshG1513 1. With whom might 23andme share my results? 2. Can I be compelled to disclose health results for purposes such as employment or insurance rating? for starters.

@crystalcenter7872 5 лет назад

Dear Destin, THANK YOU for contributing to the betterment of our class discussion in my Biology Brainiacs course today at Dale County High School in Midland City, Alabama! We have been learning the finer points of DNA and Genetics for a week now and have just begun talking about DNA testing and its' future. We have a local cold murder case that has gone viral in the news so the kids have had a lot of questions about DNA testing such as that done with 23 and Me and how those would relate to possible forensics cases. My husband subs to your channel and was showing me your channel at 4:30 this morning when I stumbled across this gem of a video. I had the pleasure of working with Dr. Lamb several summers ago and just adore the way he allowed you to tell the proper story of DNA testing in a lab setting so THANK YOU for being such an integral part of my lesson today! In True Nerd Love, Crystal M. Newsom and the Biology Brainiacs of DCHS

@TheWeirdMusic 5 лет назад

I sure do hope you approached this video with scepticism and discussed the privacy concerns. Otherwise you just left a bunch of kids misinformed and encouraged to donate their genetic profile for others profit at their own risk.

@RespawnRestricted 5 лет назад

Let's be honest. it should be called 23andMe plus the government or whoever ask for your info

@liammargetts 5 лет назад

Yeah cause the government is gonna be able to do loads with that 0.02% of DNA

@juanolotgn 5 лет назад

@@liammargetts it's the DNA that varies from person to person. No other person is going to have YOUR 0.02% that they test

@Raidixx3 5 лет назад

Yea true, id never give any of my DNA away willingly

@russell2449 5 лет назад

Moron, did you not watch the video??? They don't ever get you name, your data is strictly linked to an email account simply in order to send you the data. YES you certainly can go to their site and share more information, including name, DOB etc. but that's often more for people interested in geneology. You can protect yourself using a throwaway edress if you're that paranoid.

@RespawnRestricted 5 лет назад

You mad bro lmao

@jdpjamesp 6 лет назад

"My wife insisted on taking my place, for reasons she will explain herself." Fully expected her to say "I need a day off from looking after the baby. I'm outta here!"

@MK-ex4pb 6 лет назад

James Palmer women would never actually say that but they think it

@brentc6095 6 лет назад

The 0.02% thing seems a little bit of a misleading statistic. While it is true that is the overall percentage of your DNA, it is slightly misleading in that its not necessarily the percentage of your DNA that matters. Consider how much of our DNA is shared with a Banana (~50%) or a chimpanzee (~99%). Then consider that a not insignificant portion of our DNA is considered to be non-coding or junk DNA. All that put together could make the percentage of your DNA that they are testing for out of your total DNA that matters a good bit larger. I am far enough from an expert to not know even within orders of magnitude what that final percentage would be, but it would almost certainly be higher than the 0.02% stated. That said, that doesn't scare me off of testing services like 23&me so much as not seeing it as a good value at its current price. Thanks for the video!

@Dylan-go5iv 6 лет назад

Brent C They don't claim that percentage as part of their value at all though. It has nothing to do with it.

@billbradleymusic 4 года назад

Wow. They uncap all the different folks specimens side by side. Amazing.

@xwingday 4 года назад

Thanks for the informational video. Also tell camera shy Terra thank you for her part in making this video as well.

@Pow3llMorgan 6 лет назад

Redheaded women in lab coats.. It does something to me..

@wiertara1337 6 лет назад

Steins Gate

@catpaws1913 6 лет назад

Wojtek Kiraga I'm mad scientist So cool You sonovabitch!

@starknifez4846 6 лет назад

Povl Besser dunno why but she really looks like Sansa Stark

@MK-ex4pb 6 лет назад

Povl Besser same 😍

@doublebubleguy12 6 лет назад

Nothing in this world can compete with a redhead in a lab coat;)

@DVXCine 6 лет назад

You're not covering what happens to the Health + Ancestry Service samples or where that data is then used after you get your results. My biggest problem with this service is what they discovery in your DNA (for good or bad) can be used with any compensation to the individual because they signed those rights over to 23andMe. Read the fine print, I did. As for the physical samples be being destroyed, that should not even be an issue, the "spit" is like the plastic bottle your soda comes in as the data has be collected and is now in the system and is for sale and has been sold already to pfizer or other companies. Don't get me wrong, I'm all for the betterment, but I have to draw the line when it comes to a company making money twice.

@nanga7549 5 лет назад

Just curious, I dont mean to be confrontational or anything, but can you maybe just paste the fine print you found? Im just curious and would like to also see what, how, where, etc.

@chloe61598 3 года назад

As a lab tech, this is an awesome video. The instruments in the laboratory amaze me everyday.

@riOdariot 4 года назад

The lady at 10:20 "Oh, yeah, you are here for excitement.." 🤣🤣

@kaino5030 6 лет назад

I always greet Destin back at each intro

@smartereveryday 6 лет назад

lol. Welcome back!

@giovannistriano3564 6 лет назад

Man you must have loved Dora the explorer

@videoloops1 6 лет назад

I wish Jon Snow knew about this technology.

@pumpuppthevolume 6 лет назад

videoloops1 xD

@hearDJK 6 лет назад

*spoiler: NED STARK DIES!*

@pumpuppthevolume 6 лет назад

spoiler .....he resurrects

@SpecificGender 6 лет назад

Who needs technology when you have a third eye 😂

@mikeissweet 6 лет назад

Jon Snow from game of thrones or the real and great Mr. John Snow of the Broad Street pump?

@chrrmin1979 5 лет назад

Thank you for your transparency 23 and me. Your company scares me, but this helped. Still scared, just not terrified lol

@thefixer1993 4 года назад

Incredible... Thanks for doing this.

@magiclegend1501 6 лет назад

Full raw uncut upload of the vlogs? Getting really curious about the conversations she had :-)

@Twisted_Sync 6 лет назад

I think that would most likely be something put up on his second channel, but I'm not sure if he's going to.

@deathleopard4960 6 лет назад

he said hes saving it for the patreons

@U1TR4F0RCE 6 лет назад

They will be posted on patreon

@iamadave 6 лет назад

8:43 open spit vials and no one is wearing masks???? Am I the only one that thinks that could contaminate the samples?

@michaelamick8295 6 лет назад

IamaDave, this caught my eye as well as knowing the evaporative permeability of saliva into the atmosphere, why aren't they wearing masks for their own protection?

@muhmin7 6 лет назад

Usually the vial has solution inside it that destroys bacteria and preserve the DNA. The lab of such huge company should be strict enough with the cleanliness standards.

@MK-ex4pb 6 лет назад

IamaDave i think they crack them open, but the machine is what actually opens them. You would think they'd wear masks tho

@Saturie 6 лет назад

Yeah.. That kind of concerned me as well :|

@CoDisafishy 6 лет назад

+JassSerenity Well, seems like it's nothing to be concerned about assuming kjthoward is correct.

@IJudgeYou 5 лет назад

thank you for making learning something enjoyable and entertaining.

@deeraines9416 4 года назад

I needed this today. Thank yoou

@danthelatch 6 лет назад

Hey look Mom! I'm in a video! 1:31

@MuzikBike 6 лет назад

@moistmcman981 6 лет назад

Neat

@wr506 6 лет назад

Nice! also cool user picture

@toddchamberlain6507 6 лет назад

LOL. Hey Destin, where's Daniel's cut?!!?!? ;)

@leonblue0 6 лет назад

the "I didn't get a notification but soon because i have no life" squad

@NBFman1991 6 лет назад

RU-vid is my life

@ItsNessaTho 6 лет назад

🙋

@lrume4043 6 лет назад

🕺

@jakeakins384 4 года назад

best advertisement anyone could ask for

@ptg8134 5 лет назад

Thank you. Very interesting as I had just bought the 23andMe a few days ago. Good stuff!

@MrJayPuff 6 лет назад

This was great, I actually did 23andme not too long it gave back pretty accurate results and some surprising stuff. Nice to know they are a very credible company

@howeslife2718 6 лет назад

I feel so much better about this now. Thanks!

@shebelieves9650 4 года назад

Very informative! Thank you so much!

@joshuadavidnewmark4490 5 лет назад

Fantastic! Thanks for the video. It answered all my questions. I'm waiting for my results.

@TheAgentTexas 6 лет назад

People always say that they are concerned about privacy yet we post the things we post on social media which is public.

@ElectricPyroclast 6 лет назад

We get to choose what to put in the public. Some of us are just less smart about it than others.

@Ronniepmr 5 лет назад

2018 I have no Twitter no Facebook no Instagram and no other social media online except for this and Xbox. So speak for yourself on that one.

@emmeli5492 5 лет назад

People are mostly concerned about the details of their health and medical history. They don't want to risk it being exploited. There's a buch of other comments explaining this.

@florence4372 5 лет назад

We are concerned about privacy as if there's anything remotely interesting about us. Gg

@iprobablyforgotsomething 5 лет назад

Oh, scammers and ID-thieves certainly find it interesting...

@JimFrye1 6 лет назад

I always thought 23 & Me only sent you ancestry data. Didnt know they also send health data. Very cool. I got smarter today. Thanks Dustin and Tara!

@tomray6252 4 года назад

Kudos to 23 and Me. Thank You Destin!!

@Cassiel75 5 лет назад

Good. Comprehensive ,cogent and insightful! It was a great help**

@kermitdude 6 лет назад

This is really cool. Great video, and amazing that your sponsor gave you such freedom. They saw an opportunity to market a service that they have confidence in and you were able to ask critical questions. Kudos to you both.

@gercunderscore4 6 лет назад

Wow. One of the reasons I haven't used a service like 23&me is that I was worried about the reliability and accuracy of the results. This has allayed many of my concerns. Thanks for going the extra mile on this one.

@moviesoftheweek608 5 лет назад

5:55 spike ball, I love that game.

@kd1s 5 лет назад

I did a contract in a genetic lab in Cambridge MA. It's fascinating how much the process has in common with color film development. We used Ion Proton Sequencers. And yeah, 80GB per exome that we sequenced. It was part of the Million Veteran Program with the Veterans Administration.

@jzorreguieta 6 лет назад

I was a bit surprised to see at 8:15 that the technician that is de-capping the saliva samples before testing them is actually talking over all the un-capped samples without any sort of mouth cover, potentially contaminating the samples. Anyone else thought about that?

@captainenglish5050 6 лет назад

Any resulting contamination from breathing over a sample is negligible. The worst possible scenario for contamination would be for the technician to actually spit in the original sample, which would result in (potentially) different reads for the same location. This the concept of coverage in sequencing, in order to ensure there are correct matches: en.wikipedia.org/wiki/Coverage_(genetics)

@zx8754 6 лет назад

Contamination from foreign spit over air is nothing compared to chicken bits from your sandwich you had for lunch before spitting into the tube.

@Loccyster 6 лет назад

Zedex 12, you watch Adam ruins everything too? :P

@ServerDestroyers 6 лет назад

1. I get to ask any question 2. I get access to the labs And number 3... I want an adult sized krabby patty

@Tux.Penguin 5 лет назад

Great research Mr. & Mrs. Sandlin. Great job!

@thenoze5767 5 лет назад

"welcome to the institute" he's definitely creating synths with that DNA

@battleforevermore 6 лет назад

This needs to be a longer video... With much more information... More about the machines, more about the sites useful, how are other biological organisms removed from the as samples, what it the cost difference between full and partial genotyping.... Etc

@yashvardhannc2165 6 лет назад

Dear destin, Thank you so much for the effort you put into making these interesting videos. Recently, India celebrated teachers day, and I want to wish you the same because you have been a great teacher to me. PS: I wish I could get a high speed camera to do what you do

@chowtom5174 6 лет назад

Yashvardhan N C do you get to prank your teachers on that day?

@DraconaiMac 5 лет назад

Destin - excellent!!!! I love this! (Nice to meet Tara too)

@BeanDar 5 лет назад

Lol the beginning reminded me of the part of Venom where he starts to question the rich dude at the laboratory

@SulaTennakoon 6 лет назад

Get a man who can love you like Destin loves his wife

@VeedddeeR 6 лет назад

Sulakkhana Tennakoon can Destin just be my dad? Never had one 👌

@SulaTennakoon 6 лет назад

I'm sorry :(

@ChilapaOfTheAmazons 6 лет назад

And make sure you love back your husband. Some women forget that part.

@SulaTennakoon 6 лет назад

Chilapa of the Amazons I'm a guy actually

@kristen23231 6 лет назад

Why is no one in the lab wearing face masks? With opened tubes right in front of them and them talking there would be risk of contamination of the sample. Kinda super upset I spent my money to figure out what I am and my health when it could be crossed by someone else's spit...... 😐

@rednarok 5 лет назад

I had them test my spit twice and they were unsuccessful so I doubt others spit would contaminate it.

@rednarok 5 лет назад

@Alex Corn I'm actually quite sad because of this since I was tremendously interested in finding out my genome...

@rednarok 5 лет назад

@Alex Corn thank you so much for the information! Now I feel compelled to see what other better options there are out there. This was new to me and I thought this kind of testing wasn't readily available to the public. I'm grateful for knowing I can still have the opportunity to know more about my body! Thanks!

@AleksaNoeksa 5 лет назад

There's the AllofUS Research Program, I think they're looking for people to send in samples and they give you information for free. I guess they're trying to sequence a ton of human genomes.

@Evello37 5 лет назад

If the test was sensitive enough to pick up contamination from the breathe of the scientists in the lab, then the samples would also be ruined by customers opening the tubes freely in their non-sterile homes. Heck, there are tons of organisms living in your mouth and saliva that could contaminate the sample. These types of DNA tests are designed to be very robust even with small amounts of contamination. The fact that there will be vastly more customer DNA molecules than contaminants means most results will be correct by default, even without doing anything further. But tests can also use tricks like placing multiple redundant copies of the same probe to rule out contaminants. Basically, a test that requires perfect sterility would not be cost effective. Having worked with DNA a lot myself, the scientists could probably work with their bare hands and it still wouldn't matter.

@NewManToHandle Год назад

You folks did a great job!

@FrostbyteCoins 3 года назад

It’s awesome that your wife was so cool to do this. Thank you

@Dloweification 6 лет назад

The privacy concerns were never about how they dispose of the samples or how much data they collect. It is who has access to that data. Once they find out that you're genetically predisposed to something, what is to prevent an insurance company from getting that information and charging you more or flat out refusing you insurance, or if you DONT disclose that to an insurance company and they find out that you knew, they could refuse to pay for treatments you received.

@AtrumNoxProductions 6 лет назад

I almost did this for cyber Monday. Amazon had it for 50% off, but I was a little concerned. After seeing this I wish I had did it.

@captainenglish5050 6 лет назад

I wish I had *done it

@MK-ex4pb 6 лет назад

AtrumNoxProductions better safe than sorry. Maybe next year

@MK-ex4pb 6 лет назад

CaptainEnglish if you were really Captain English, you would know that there is no correct usage. If you're understood, which he was, you're correct

@FillingTheGap1 5 лет назад

Used your link. Really looking forward to seeing my results.

@uIfsark 3 года назад

"this is like from the future" Windows XP pc in the background: "Well hello there"

@tonymusic720 6 лет назад

My daughter asked me what DNA stood for... I told her it was the National Dyslexics Association.

@jocaleb0236 6 лет назад

8:26 WINDOWS XP MASTER SPECIES

@mitigiant5328 5 лет назад

LOL

@vladmircea7275 4 года назад

talk about "privacy"

@AS-qj6zf 5 лет назад

Waiting on my results right now which just got to the genotyping step... this definitely gives me a better perspective about what’s happening behind the scenes there and where my spit ended up.

@ThrowItOnTheGrill 5 лет назад

Thank you for posting this informative video. It was refreshing to see something that took a brain to watch. It's the best video I've seen on here for a long time. It answered some questions that I had about these DNA tests, too.

@sufiyansamir7143 6 лет назад

8:12 "This is like from the future" 8:20 *Finds WindowsXP* 😃

@dege13 4 года назад

Can you deep dive the way the analyze the ancestry data? I've heard very mixed things about it and how their sample data doesn't scientifically give them the level of certainty that they imply with their reports to customers.

@oakune 5 лет назад

This honestly deserves more views

@jennhoff03 4 года назад

I did my DNA through Ancestry and then ran it through a health program called Prometheuse. I did it because everyone in my family dies of cancer, and I wanted to see if it said I was genetically predisposed. Well, guess what? It came back and said I have the BRCA-1 gene mutation, the gene that gives you a 70% chance of breast cancer and 40% chance of ovarian cancer and a high risk of other cancers. I was so upset. I grieved, I obsessively researched, I cried.... it was terrible. Then I went to my gynecologist to discuss my options. She redid the test just to be sure, and 2 months later.... it came back negative. Turns out I never had the BRCA-1 gene mutation; Prometheuse just told me I did. I spent 3 months of my life freaking out and telling my family to get tested... It was rough. So user beware when you get your results back! :(

@KLHKLH 4 года назад

I'm not sure if it's true, but I've heard people say that if your insurance company knows that you're genetically predisposed to a certain disease, they can deny you coverage. This was before the health care laws changed, but it's still something to consider before getting tested.

@jennhoff03 4 года назад

@@KLHKLH Ohhh, I never thought of that! What an interesting point.

@thief9001 6 лет назад

What ISN'T in Huntsville?

@alexlandherr 6 лет назад

The rest of the observable universe.

@chowtom5174 6 лет назад

thief9001 in Hong Kong you get the impression it's only finance finance law finance law law finance

@kacperk886 6 лет назад

Opals. But that's a different video.

@theonlyari 6 лет назад

The Titanic

@leslieparson5443 6 лет назад

Me?

@julienjanet4669 6 лет назад

As a medical student, i'm not sure about the .02% that are analysed. I think 23andMe analyses ~600.000 sites in your DNA in which each site includes several bases. So I think it is much more bases that are analysed than only .02%. As for the health data, it would be interested to know, what 23andMe does if they find out there is a genetic disorder that can lead to a genetic disease, for exemple SNP (single nucleotid polymorphism) and bigger rearrangement (like micro duplication or micro deletion). In these kind of test, whe should be told what we can expect from it and what we can't. Sorry if my english was bad, I'm not a native English speaker. Great video as always

@drakan4769 6 лет назад

I think they do tell you at one point that you can choose whether to opt in or out of heath related information

@lizveta4843 6 лет назад

Julien Janet they do analyze way more than the health reports they are allowed to give you. You can download your 23andMe report and have the whole thing analyzed for $5 at Promethease.com.

@blackberrybunny 5 лет назад

This was a great video. My spit just made it to the lab today! I am excited, waiting for results.... this video helped me understand how the process works.