In this EPicks videos, Jun Sugawara talks about their research paper on 'Attenuated pulsatile transition to the cerebral vasculature during high-intensity interval exercise in young healthy men'.
Find out more in Experimental Physiology:
'Attenuated pulsatile transition to the cerebral vasculature during high-intensity interval exercise in young healthy men'.
Jun Sugawara, Takeshi Hashimoto, Hayato Tsukamoto, Niels H. Secher, Shigehiko Ogoh.
108 (8) pp. 1057-1065
physoc.onlinel...
Transcript:
Hi, I am Jun Sugawara.
Today, I goanna talk about the windkessel function of large elastic arteries. It expands and recoils against cardiac ejection. As a cushion and pump, it makes intermittent, pulsatile flow to continuous steady one. It is important for brain health.
There is an attractive exercise mode, high-intensity interval exercise (HIIE). It evokes excessive systemic hemodynamic fluctuations, which may stress the brain. Accordingly, we tested whether the cerebral vasculature is protected against systemic blood flow fluctuation during HIIE.
Fourteen young healthy men underwent four 4-min high-intensity cycling bouts. During the protocol, aortic pressure and middle cerebral artery blood velocity were simultaneously recorded.
We characterized hemodynamic pulsatile transition from the aorta to the brain using transfer function analysis.
The main findings are that transfer function phase was increased, and gain was attenuated during HIIE. Time-domain index was also lowered during HIIE.
Our findings suggest that the arterial system to the cerebral vasculature may attenuate pulsatile transition during high-intensity interval exercise as a defense mechanism against pulsatile fluctuation for the cerebral vasculature.
6 сен 2024
