Gout: Glycine Lowers Uric Acid!

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In this video Dr. Pete discusses the uric acid lowering properties of the amino acid glycine. Most gout sufferers are hyperuricemic (high uric acid) and many of you take urate lowering drugs. Glycine may offer an alternative to drugs like allopurinol or can be coupled with a urate lowering drug to more effectively lower uric acid.
Dr. Pete proposes a comprehensive model of gout, obesity, diabetes and the best practices to put gout in remission and reverse obesity and diabetes. His ability to breakdown the science into understandable terms is unmatched and no one else in the low carb space can match his depth of knowledge concerning fructose/uric acid pathway and potential remedies for the number one inflammatory arthritis in the US and the worldwide epidemic of obesity and diabetes. If you suffer from gout, obesity, and/or diabetes makes sure and watch this presentation. It can change your life.
Find Dr. Pete at www.drpetesgoutintensive.com
Find Dr. Pete at www.drpeteandt.com
Email your questions to peterdelannoy@drpeteandt.com
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Email Dr. Pete here: peterdelannoy@drpeteandt.com
Some References: 1) some references appear in the presentation 2) Click the link for general reference and crystallization papers here: docs.google.co...

Опубликовано:

11 сен 2024

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Комментарии : 99

@sgtaneja 4 месяца назад

Glycine is my favourite amino acid. I have 3gms -5 gms on regular basis. Its excellent for gut, liver, gall bladder, kidneys, brain & heart / vascular health.

@g33k37 11 месяцев назад

Hey, I just found your channel from the algorithm. We started giving my grandfather, who's 92 glynac in July. We did this to try and help his heart failure. Which seems to have worked fantasticly. He's also suffered from kidney infections as well as kidney stones for years. He had a large stone removed from his left kidney in April that was removed via surgery, it was too big for standard lithotripsy and they were going to go after the stones in his right kidney only when we did the CT SCAN two weeks ago to find all the stones were GONE! It's absolutely amazing, and his urologist is scratching his head. Because we know he didn't pass them. So something between Glycine and Cysteine has had a major effect on his kidneys. As his eGFR is going up as well.

@DrPetesKetoKlub 11 месяцев назад

Awesome news! Keep up the good work.

@v-22 10 месяцев назад

That is an amazing story given he's 92 and has had all those issues. Well done!

@feli931 8 месяцев назад

Hi my father who is 89 years old is going through similar situations what was the mg you him.

@questingspangle 4 месяца назад

What dosage of glynac is he taking?

@g33k37 4 месяца назад

@@questingspangle 3.0 -3.5g twice daily with 2.0 Taurine twice daily as well

@blackbart5803 10 месяцев назад

A mix of rutin and quercetin lowered my UA from 7.5 to 5.1.

@devaapurna608 29 дней назад

Thanks!💖

@michaelberman3648 2 месяца назад

I also take the magnesium-L-glycinate as a glycine contributor with additional supplementation of NAC to form glutathione with the assumption there is excess glutamine in our tissues.

@doomsdaycompass3279 2 месяца назад

Since 2020, I substituted glycine as a sweetener, and stopped sugar. I used it to make my own Whip Cream. Though I don't use a lot of heavy cream any more, I still use glycine to sweeten my hibiscus tea, to sweeten my Golden Milk, and to sweeten my morning Cacao, I don't sweeten my coffee, since I take it black for its bitter taste. During Holidays, we make a blueberry salad with heavy cream, sour cream, gelatin, and glycine for the base. Blueberries are in a gelatin, as well. I found glycine can lower post prandial spikes. And it can help sleep. I take at night -- Golden Milk -- with Ghee,Turmeric, Cardamon, Nutmeg, and Saffron, all sweetened with Glycine. Or I take 3 bags of Green Tea for L-Theanine, sweetened with Glycine before bed time. Now I will experiment with Glycine, and try to lower my Uric Acid levels, as I have been a carnivore for two years. Now, I eat my meats on the weekend, following a 5:2 PSMF schedule. During the week, I eat egg whites, some goat cheese, and whey. Lowering my saturated fats during the week to avoid palmitate. I followed a similar Gout diet in 2005 and I lost a lot of weight, and reversed my gout using yogurt, cheese, and eggs. It was a Keto diet based on Barry Sear's Diet books. Today, Quercetin, Coffee, Elderberry, Tart Cherry, Garlic along with Vitamin C is how I reduce Uric acid.

@DrPetesKetoKlub 24 дня назад

Congrats on finding something that works! I think glycine is a really good supplement.

@tonir6532 9 месяцев назад

Blue berries in fresh or frozen form and sour cherries in frozen or canned form or frozen form work to reduce/ remove uric acid and pain and remove osteo arthritic pain in fingers and toes.

@trevormarcray 8 месяцев назад

Your channel is great. Really helping a friend of mine who is trying keto but has gout issues on it. Thank you so much

@sugarandfoodaddiction9868 8 месяцев назад

Thanks for the comment! I work really hard to try and help with the gout.

@DrPetesKetoKlub 3 месяца назад

Thank you!

@juliaappleton17 Год назад

Thank you. You have been a beacon of wisdom for me. Appreciate your work is vital.

@SL-ml6fy 7 месяцев назад

Have followed your advice for several months and have not had a gout flareup but like you said my UA level is still quite high. Will be trying Glycine and will see if UA will come down. Thanks for sharing your knowledge !!!

@DrPetesKetoKlub 3 месяца назад

Go slow and take your time. Sudden fluctuations in UA can set off a flare.

@faisal-ca 10 месяцев назад

I have been gout-free for ages but have a slightly higher Uric acid. I have recently introduced Collagen and hopefully, it's going to give me enough Glycine.

@johnwick-mh9ry 6 месяцев назад

how did you manage it? thanks in advance.

@faisal-ca 6 месяцев назад

@@johnwick-mh9ry I don't know the underlying cause. I got gout when I went on a pure protein diet, eliminating everything else. After that, I kept on having toe discomfort or small flares. Then it went to remission. I took a more balanced approach to diet. My last blood work showed UA is within the permitted range.

@sgtaneja 4 месяца назад

Collagen and Glycine are Not functionally equivalent. Besides, to breakdown collagen, you need to start with nano hydrolyzed collagen peptides, then have enough stomach acids and proteases to break down those collagen peptides, and you'll also need cofactors like vit B6 in active form to process the peptide aninos to finally get to Glycine ! Soln : Have free form Glycine directly !!

@dregbayonsaymay 4 месяца назад

Doc thank you for this

@saxgirlhornboy6458 Год назад

Interesting info, thanks.

@reviewer5286 2 месяца назад

Thank you Sir!

@DrPetesKetoKlub 24 дня назад

Your welcome!

@EarmuffHugger 6 месяцев назад

I'm on it !! SUBBED 👍

@Nero_1069 4 месяца назад

the problem with alternatives to allapurinol is if it doesn't work you have to suffer yet another excruciating kidney stone.

@DrPetesKetoKlub 4 месяца назад

Maybe. This remains unknown. One thing you can do is take potassium citrate in the appropriate dose to elevate the pH of the urine and lower the probablity of a stone. The best use of allopurinol is the lowest possible dose to get you to your target with elimination of the drivers of UA production and maintenance of a low inflammation environment.

@Nero_1069 4 месяца назад

@@DrPetesKetoKlub Cheers.

@RoiPourpre 10 месяцев назад

Hello, no risk of uric acid stone in the kidneys by doing that ? I don't have gout but my Uric acid level is at 6.9, not good for cardiavascular health :( Ty.

@DrPetesKetoKlub 10 месяцев назад

Yes. Maybe. 2 things; 1st any urate lowering strategy like this that works on excretion or on production (like allopurinol) can bring on a flare. 2nd; with glycine I also take potassium citrate to increase alkalinity of the urine, raise solubility of urate, and decrease chances of a stone.

@RoiPourpre 10 месяцев назад

Thanks for your answer ! Have you tried quercetin ? Just find that this work nicely , im going to try this for the next 3 month and see if it reduce a lot my uric acid. Never got a flare but, i really hope im not going to have one... @@DrPetesKetoKlub

@RoiPourpre 10 месяцев назад

Do you still use Quercetin ?@@DrPetesKetoKlub

@paulyoung3504 Год назад

Hi Dr Pete. What's your opinion on creatine. I'm 60, in gout remission for just over a year and on a low carb diet but not keto. Thinking of trying out creatine, 5 grams per day, but noticed there's next to no RU-vid videos discussing gout and creatine. Thanks, Paul Y

@DrPetesKetoKlub Год назад

Be aware that in the 60's biochemists showed that crystalline creatine could cause the same symptoms of gout as monosodium urate. Just FYI.

@paulyoung3504 Год назад

@@DrPetesKetoKlub ......Thanks Pete. I'm not on any anti-gout medication like Allopurinol because my gout attacks only occur maybe once a year to 18 months, but I have colchicine on standby if I need it. (Gout is the strangest problem I've ever had...no real pattern to it. ) Thankyou for all your advice.

@zaxtoy2431 5 месяцев назад

I take Trimethyl glycine. Would that lower Uric acid the same as regular glycine? If so, are the dosages the same? Does anyone know? Thanks

@DrPetesKetoKlub 3 месяца назад

I don't know.

@michaelberman3648 2 месяца назад

I am taking liberal amounts of Magnesium-L-glycinate. I take this compound for a variety of reasons including its ability to activate vitamin D3 to its physiological potential. Can this compound I am taking also act as a significant contributor as acting also as a glycine supplement?

@DrPetesKetoKlub 24 дня назад

I don't know. But you could do an N1 to find out. This would involve measuring UA by finger sticking. Stop the Mg-L-glycinate. Monitor UA without altering anything else in your lifestyle and watching to see what happens to UA.

@wocket42 11 месяцев назад

Bone broth is mostly glycine. No supplements needed

@NickCager 4 месяца назад

Really? Wow... I just had a large glass of bone broth before reading this...problem solved!

@copie77 3 месяца назад

Problem with bone broth is it’s super high in purines

@NickCager 3 месяца назад

@@copie77 I didn't know that, thanks!

@doomsdaycompass3279 2 месяца назад

Bone broth is umami

@v-22 10 месяцев назад

My kidney functions are of a healthy 20 y/o. I am lean, athletic, I have perfect blood pressure, great cholesterol and glucose levels. I have no other issues except for gout while my UA levels are under 6, so, explain me that because no doctor has been able to thus far.

@jonathankuhn2180 10 месяцев назад

I know, if you really research gout, seems people have hyperurcemia with no gout, people have monosodium urate crystals in joins with no gout, people have gout without crystals in joints, people have gout without high uric acid levels. It seems like there is a strong correlation with the crystals and uric acid, but I am not convinced it ends there, the medical establishment doesn't seem to care about us and getting to the bottom of different diseases, they have their treatments, and thats about it. It does seem a few people are an exception to this rule, I pray more and more people continue to contribute and help humanity toward health through their research and efforts. We need to be our own advocate and research as much as possible. Dr Pete has a good point, it could be a form of pseudo gout.Oxalates can do this too.

@DrPetesKetoKlub 10 месяцев назад

You may have the inflammatory condition that promotes formation of the seed crystals which can persist for years without the shift to the painful flare. There is also the possibility of other crystals like calcium phosphate and oxalates. If you are supplementing creating, calcium salts in protein powders, these can be potential contributors to seed crystal formation.

@v-22 10 месяцев назад

@@DrPetesKetoKlub My CRP is super low and the only supplements I take I just started taking, I've had gout for 9 years. I'm telling you, I even heard it could be a B5 deficiency- it's not. I have not idea, doctors have no idea.

@sugarandfoodaddiction9868 10 месяцев назад

Unfortunately you are correct. We don't know the cause of gout. We know that UA is required for the flare but UA is not sufficient. There are other factors--at least one protein--involved in the flare. Additionally, soluble UA is also involved in addition to the crystal. We do know that average UA doesn't drive flares. Large swings up or down in UA in a short time frame drives the flare. The best thing that you can do is make sure that you eat a whole, real food diet. Eliminate the drivers of Fructose/UA metabolism: hyperglycemic food (grains, potatoes, rice, etc.), any/all added sugar, alcohol, and Unami ( any packaged, processed foods including processed meat.) Eliminating the drivers of UA reduces the probability of large swings in the concentration of UA. One last thing: Sleep apnea is a known driver of gout. Get tested if you have not done so. Even if you think you sleep great, get tested. The reason is because sleep apnea causes regular hypoxic events through the night which activates Fructose/UA metabolism and can cause frequent large swings in UA and subsequently the flare. Hope this helps.

@v-22 10 месяцев назад

@@sugarandfoodaddiction9868 it's not sleep since, after I sleep, my gout always improve which is why I force myself to sleep as much as possible. It has happened in many different circumstances, when I was eating well and lean, when I was not, which is why it makes it impossible to pinpoint the cause, but thank you!

@id9139 4 месяца назад

Can you eat red meat if you have high Uric acid????

@kenshey3912 10 месяцев назад

I found many of these glycine studies… all referenced taking with tryptophan (a sleep assistance supp). Do you take the tryptophan? This current flare has been happening for a month now… not sure if I should drop out of keto or not. Lots of proteins but ratio is 80% fat Would love to see a new video on your glycine potassium citrate doses

@sugarandfoodaddiction9868 10 месяцев назад

I use the tryptophan off and on. I just didn't see the enhanced drop suggested by the papers. I use 1 gram Kcitrate with 3 grams glycine per one drink. I shoot for ~9-12 grams total glycine per day.

@kenshey3912 10 месяцев назад

@@sugarandfoodaddiction9868 thanks Pete,.. I’ve got some numbers to start working with. PS UA was travelling along 9ng since I got the meter. Much tighter on protein to fat ratio especially if I have any chicken. I suddenly dropped into the high/mid 7s but goal is 5s I have allopurinol but I’d like to see where I level off N=1 Data is power … n=many is even better

@DS-mr7gr 6 месяцев назад

When I started keto about six weeks ago, I had a 4 to 5 day mild gout, attack myself. I’ve had a few attacks of the last 3 to 5 years, and when I diagnosed for probably the first 3 to 4 years of that. Hopefully, yours will improve soon. I’ve read that infrared sauna can help excrete excess your acid, as well as foods that remove toxins from the body. But a lot of those are not keto.

@adamshand 5 месяцев назад

keto adaptation is known to cause gout flares. as you adapt the gout should settle down. it took me two months ...

@DS-mr7gr 5 месяцев назад

@@adamshand I came off Keto about a week ago, having been on two months and my trick acid levels were high. I’ve decided on my own to switch to something else. Although I like keto for certain reasons, I’ve come off and eating more nutrient focused.

@2tennhills 4 месяца назад

QQQ DOES GLYCINE exacerbate cancer

@peterdelannoy 3 месяца назад

I don't know.

@doomsdaycompass3279 2 месяца назад

No. Serine is an amino acid implicated with cancer. Protein restriction, in general, is recommended for Cancer, particularly restricting Methionine. Glycine N-A-C Taurine are recommended for longevity since they boost glutathione. Prolonged fasting with Vitamin C is a protocol being developed by Dr. Valter Longo

@privatesuzie4071 11 месяцев назад

Pete, are you still taking allopurinol? Suzie

@DrPetesKetoKlub 11 месяцев назад

Yes. But I am experimenting with 12 grams glycine per day and reducing the dose of allopurinol. Also, maintaining potassium citrate.

@kenshey3912 10 месяцев назад

Pete… how long before you saw potassium citrate affects

@DrPetesKetoKlub 10 месяцев назад

I take kcitrate with glycine to increase pH of urine. You can monitor pH with pee strips. Glycine lowers UA by excretion so using Kcitrate lowers risk of stones. Glycine allows me to lower allopurinol.

@healthyselffirst6845 10 месяцев назад

@DrPetesKetoKlub how much K-Citrate do you take per day? And how do you take it?

@sugarandfoodaddiction9868 10 месяцев назад

@@healthyselffirst6845 3-6 grams usually mixed as a drink with 3 grams glycine. 1 gram Kcitrate, 3 grams glycine.

@keylanoslokj1806 10 месяцев назад

Sir how do we avoid high uric acid? Do we avoid tomatoes and spinach? What other lifestyle factors contribute?

@mreudeco 5 месяцев назад

That’s for oxalates

@biggpimpin20 17 дней назад

does taking magnesium bisglycinate counts? or it has to be straight glycine?

@evelynsimmons7602 Год назад

*Promo SM*

@Unsensitive 4 месяца назад

Interesting. glycine also improves metabolic function. I've heard metabolically healthy individuals with elevated fasting blood sugar using glycine to lower their fasting blood sugar from the low 100's to 80's. Makes me wonder if it's the metabolic improvement helping the kidneys lower uric acid, or lower uric acid helping metabolic function.

@DrPetesKetoKlub 4 месяца назад

No doubt that UA is required for optimum metabolic health. However, how much is too much remains to be determined.