Methylfolate may make someone more depressed especially if they are undermethylators of neurotranssmiters because folate increase neutrotransmiters transporters production which lead to lower levels of those neurotranssmiters in the brain and because of that fact people who are undermethylators will see improvement at start but later it will get worse and in those cases i would reccomend much more protein in your diet. Remember that if you have no idea what you are doing then dont try to mega dose vitamins/nutrients because you may get more harm than benefits, its always better to experiment with your diet and see how you feel.
Great video. I have homozygous c677t mthfr mutation. So mu mthfr functions at 25-30%. Im gonna start taking methylfolate, methl b12 and p5p. Ive had depression, anxiety, sleep problems all my life. B12 has always given me crazy amounts of energy. But im gonna take it in combination with methylfolate and p5p.
@@swintegrative I seem to not respond to well to b12. It gives me a lot of energy and messes with my sleep. I think I have the reaction because my body is not used to high levels of b12. I've read that this happens to people with these mutations. Have you seen this?
I had severe depression for 5 months, trying 4 different antidepressants. They did not work. One week on methyl folate and methyl cobalamin and the depression was gone in five days.
