How do allergy shots work? | Th2 cells and IgE 

I'm the same. Had to research about it first. I'm about to start the journey as well.

I'm sorry you are in the horrible allergy club too. I do really appreciate what you said. It makes me really happy as a teacher!

How is it now my friend 😢, i just do blood test for allergies and i found my allergy in high rate. I wonder how the shot work and does it work?

Is SCIT helping you?

Have you experience any improvement yet??

Are you done with injections?Are allergies gone ?Did you find any change after having shots?

@@asfiajabeen9366 I'm actually still in the process of taking them, it's supposed to be done over the course of 5 years, with a reduction is injection frequency over the course of 5 years. I did notice a huge difference to how my body reacts to dust and dust mites. Less mucus buildup and sneezing. Hopefully that answers your questions.

I also want to know this :(

Yes.

I developed a chronic inflammatory disease called Polychondritis with renal involvement after receiving these vaccines for 1 year, allergen immunotherapy activates the Th1 and TGF-β , which is responsible for the pathogenesis of many inflammatory diseases, there are cases of lupus development in people who have used allergy vaccines In my experience, the best thing you can do is ask both your rheumatologist and allergist to work together. My health was destroyed by these allergy shots.

Yes dog dander sublingual treatment can help with that.

I suffer from Relapsing Polychondritis, an immune-mediated inflammatory disease, I developed the disease at the age of 13 in the distant 2002 during the application of allergen-specific immunotherapy (SIT). Because allergen-specific immunotherapy causes changes in the immune system, it is possible that it may influence the induction of diseases mediated by the immune system, such as autoimmune diseases, even some doctors point to the induction of autoimmunity as one of the possible consequences of long term of the SIT. It appears that increased concentrations of IL-10 and TGF-B, as well as changes in the Th2/Th1 balance, could lead to autoimmune problems in people undergoing SIT. Relapsing Polychondritis is a Th1-mediated condition. In the medical literature there are several cases published over several years such as that of Dr. Ghorschi et al, “Manifestation of rheumatoid arthritis during subcutaneous allergen-specific immunotherapy”, “Scleroderma related to specific immunotherapy. Maciel BM Clinical Case, Morphine BM.” “Turkcapar N, M. Sjogren’s syndrome induced by specific immunotherapy.”, Pemphigoid-like reaction by allergen-specific immunotherapy: an unusual adverse reaction Margarita Tomás-Pérez, among others. The MDs, PhDs. Allan Linneberg and Andrzej Bozek carried out investigations where the cases of autoimmune disease that have occurred during or after the application of Specific Immunotherapy published in the medical literature are pointed out, their conclusion is that the development of autoimmune diseases in patients with allergic diseases undergoing SIT it is rare, but as a precautionary principle it is extremely important to evaluate people in terms of the risk of autoimmunity before the application of allergen-specific immunotherapy. There are several cases of people who have developed autoimmune diseases during this treatment, many of these cases have not been published, and as Dr. Linneberg mentions, it is a sensitive issue that important measures must be taken. In the main guidelines for the use of specific immunotherapy, such as the EAACI and the DGAKI, this delicate topic is mentioned. Research and published cases acknowledge the great ignorance and uncertainty that prevails in this area and calls for a strong precautionary principle in relation to allergen-specific immunotherapy and the risk of autoimmune diseases. I was treated negligently by an allergist member of the National Council of Clinical Immunology and Allergy (CONICA) in Mexico, my case was not published in the literature.

@@carlosromancastaneda1138 wow Im sorry this happened to you..thank you very much for taking the time to write such detailed response..I am sure it will help many people who read this..bless you and if you speak spanish like I do muchas gracias y cuidese..mejor lo mas naural posible para no enfermamos de esa manera 💕

@@isabellashirahmadi5704 Muchas gracias!!!

@@carlosromancastaneda1138 It's awful to hear what you are going through, hope you are able to keep it under control. I am reading that this is a risk only for those who are already diagnosed with rheumatic autoimmune diseases (RAD). Were you already suffering from that when you started AIT/SIT?

I think it’s more like teaching your immune system ‘hey, look, this allergen doesn’t actually pose a threat, so chill’

Still got it twice, it was awful. I guess my body just overreacts to everything. Too much inflammation probably

@@theunseen3 I was being sarcastic. The mrna shots are a gigantic shitshow.

Alright I will remove the video for you