In my 50's, after decades of eating crap, mood swings, no sleep, brain fog, exhaustion, pain and other miseries I finally figured it out. Took six months to turn things around. Little to no carbs, keep that blood sugar low low and its even steven all the way. Thank you Dr. Perlmutter, Momo and Casey. You guys and Doctors like you are the real health care providers.
I’ve been tracking my blood sugar after every time I eat per my doctors request because of my high blood sugar. I learned my body cannot tolerate ANY beans or grains of any sort cause I tried them all. Fruit is totally out except blueberries and strawberries. Tomatoes are the same spikes my glucose. I am perfectly happy with my new diet. I’ve been pre diabetic with each pregnancy and when I went into menopause. So this new stage is just the obvious outcome as I am now a senior. I still walk 3 miles a day and am super active but I need to tweak my diet. I feel so much better and I love my new eating strategy. I am not missing out on anything that I can’t live without! But testing my blood sugar 4 times a day isn’t fun 😢😢 here’s what I do eat, I put everything over salad instead of potatoes, grains or beans. I don’t eat any desserts or ice cream. I use nori which is the seaweed that sushi is out with as my nighttime treat. I am Asian so that’s not a stretch sine I was born in Korea. BTW shredded cabbage is a great addition to any salad, soup or stew. It keeps my digestive system & blood 🩸 sugar happy 😊
Both guests were absolutely amazing. The guy in the check shirt is like the Elon musk of the gut/biome/health space 😄 data/systems and relentless work ethic 👏🏼
We are lucky to have access to such brilliant scientists. I try to listen to everything they say. They do tend o be overwhelming with scientific details. We need simpler explanations. You are way beyond most of us with your knowledge. Thank you for what you do and keep up the excellent work.
This is a wonderful class. Thank you all. But please what does high mean? Dr. Perlmutter: "Why do we care if our blood sugar is "Elevated" after a meal?" Dr. Casey 6:23 When we are spiking our glucose levels to a "high magnitude" and frequently..... Dr. Perlmutter Min. 8:55 Persistent "elevation" of blood sugar. I think you should say the level not just say high or elevated.
My husband and I have been learning about gut biome for the last 5 years and we have been waiting for someone to link specific bacteria to specific health issues but having AI do the work for you would be great too. If anyone knows of data on specific bacteria and it's link to health issues please share.
Very interesting, especially in the view of two people same food different blood sugar results and linking to other foods consumed as a meal and overall effects rather than in isolation as is so common.
Great information that has connected a lot of dots for me. About 15 years ago, in the face of an explosion of excess body weight, obesity type 2 diabetes the Canadian government dismissed sugar as a factor based on a study that found sugar consumption in Canada was in decline in opposition to the upward trend of obesity and type 2 diabetes. The study turned out to be a $tudy because it only looked at sucrose, the common name for sugar. Fructose consumption was trending in lockstep with obesity and type 2 diabetes. But fructose is not table sugar.
from my perspective, it is all about triggering GLP-1 and PYY output by short chain fatty acids from the right gut bacteria. regarding the blood sugar response to a sweet potato: different microbiomes produce different molecules from fiber. if you get a lot of propionate and butyrate from fermenting the fiber of the sweet potato through the right gut bacteria then the L cells produce a lot of GLP-1 and PYY. the pyy tells the brain to lower the ghrelin hunger hormone, GLP-1 tells the alpha cells in the pancreas to lower overproduction of glucagon and then the liver lowers gluconeogenesis and that is what we want. have less amino acid wasting for gluconeogenesis and change the fuel mixture from glucose to fatty acids and sometimes also ketones which is also nice for brain health. am i right or am i right? i was so happy when my ketogenic diet worked like a charm. dropped 25kg without being hungry. high blood sugar went away completely. the problem after a year: i had a tooth infection and also an ear infection. i had to take two times two packages of anti-biotics. and these antibiotics did their job very well and destroyed my good bacteria. that was my problem. 29kg of weight came back and now i try making different yoghurts and kefir to fix this problem. i think this will work, but this is not a process for a few days. it is probably a process of weeks or months. to fix that.
Can I hire you to read pubmed articles for me lol. I’ve been trying to fix my issues with my energy regulation / blood sugar / insulin resistance for 10 years. I was a healthy 25 year old, 5’8 140 pounds now I’m double the weight and feel like I’m not going to make it. I can’t do low carb because my brain doesn’t get enough glucose. Even lowering some carbs makes me like this. I’ve tried every diet every combination of foods, etc, seen 30 doctors, 4 holistic integrative drs and 2 naturopaths. I just want to give up at this point. I’ve got issues that I can’t find that anyone else has (I’m in tons of fb groups). I did my own genetic testing, tons of other tests. Basically I can’t fast between meals, as soon as the food runs out I have to eat again or my body starts shutting down. I know the insulin resistance had a role in this but even when I was very healthy, I could never go all day without eating. I also have to eat fat with each meal and protein too or I get so shaky and crazy feeling, but if I reduce my “bland” carbs in a meal, food shoots through me and I get so sick. So I can’t make progress with my high insulin levels. Also if I get very bloated or something is really messed up with my gut, I can go longer without eating, whatever the thing is that makes my body start shutting off I guess just turns off. No one believes me about most of this. Anyway thank you for your comment because I think my gut bacteria plays a role in my issues because I have high inflmmation too.
This sounds gross butt..... maybe a fecal trasnsplant will get you on the right track? I think your bad bugs have taken over? Been on a lot of antibiotics,ibuprofen etc?
I can imagine a future where the use of bio feedback monitors like Dr. Casey is developing is combined with Dr. Momo's machine learning logarithms to individualize not only what foods to eat, but also when, how often, and how much. And the timing and quantity will be customized to the day of the week, seasons, exercise levels, age, hormone cycles etc. We need to also pair these technologies with evolutionary biology logic.
Indeed it would make a great science fiction story. And the technology would only be available to those who can afford it. Right now however it seems to me that this may just be a whole lot of smoke and mirrors driven by the prospect of huge commercial profits. Theranos lessons forgotten already? Just a thought.
My family suffers from diabetes. My doctors say I’m not a risk but I’ve been feeling problems with my blood sugar since my teens. Thank you for this information. I can’t wait to learn more.
Super interesting. I'm wondering how this computer generated meal plan would work for someone like me who can only eat about 6 different types of vegetables (no fruit and nothing raw) due to severe gut issues. And also wondering whether this needs to be regularly reviewed. I'm doing the GAPS diet right now and it's so wonderful to find an eating plan that works. GAPS slowly reintroduces different foods as the gut heals so it makes sense that any meal plan would change as the gut recovers.
I love the way you talk about specific foods that do this, that, and the other thing, but you omit what the specific foods are. That's really helpful, and presumably it means that you are selling something.
@Pink Meta 21 in the US, that’s what I was told. I’ve also been told they’re super expensive and much less costly in other countries. A stick in your finger monitor requires no prescription.
@@DavidPerlmutterMD i have a CGM if ur blood sugar goes up AS YOU ARE EATING sayvb4 eating it was 100 then as u r eating it goes to 200 is that normal or should we only be concerned about bs 2 hours after eating? It is very vague
Im on the Levels waitlist, probably at the bottom. Just found out I'm APOE4/4 and am tumbling down the rabbit hole. Wish I could get my hands on continous glucose monitor without a Dr perscription. My dr told me not to worry about my sugars at 95 and not a peep on a major jump in cholesterol. So done with standard take a pill mentality.
I been on Metformin 2000 Mg for almost 18 Years and The Lowest I can get my Hbac1 is about a 10.3 , I am getting 11 and 12.3 's every 90 Days for the Last 15 Years and before the Metformin I was getting 16.3 to 22.0 , I Put the Insulin in the Icebox . I have never taken it yet , I had Triglycerides of 512 . I have been on Vicodin since 1993 I am up to 7 or 8 of the 7.5's a Day with Coffee , I still use Coffemate powder and Real Sugar in the Coffee . My Meals are Now Cheese . EGGS , BEEF Flax Seed Bread . Lot's of Butter from Ireland , I quit Booze in 2015 , I am a Pureblood , No Jab since 1974 . I get upset I can no longer enjoy the foods I could have when I was Younger and that Johnny Paycheck can eat 128 Hot Dogs and White Bread and Still Live . :( QC
It is so difficult to get the medical community to get going on this concept. I volunteer at a nursing home where the first thing you see when entering the front door is a giant Coke machine. Most patients are there due to some form of metabolic disease. The diet served to the patients is high in sugar including sugary drinks. Obesity among the staff is 40%.
"We enrolled 550 people... "...2/3 of their meals over the next two weeks we provided them. We actually had 10 people shop at Whole Foods. We spent $350,000, shopping at Whole Foods..." That works out to $636 per person for two weeks or $318 per person for one week or$46 per day or $23 per meal! If they used the Whole Foods groceries to make their third meal of the day (did they all eat 3 meals a day?), You paid $15 per meal. That why we call it, "Whole Paycheck." You got off cheap.
Dr Casey is very vague; when wearing a CGM, when u refer 2 postprandial, is she referring to blood sugar levels AS U R EATING? OR 2 HOURS AFTER EATING? It needs 2 b clarified.
Learning all this information about health on the internet I am wondering where I start taking steps to improve potential health issues. How do I present all of this to my GP and not be ridiculed? Why are we still left only with the private companies to do such things as testing your microbiom, trying diets for certain health problems etc? How can there be such a gap between modern science and traditional medicine? Why nobody talks about this on these podcasts?
I think people who develop type 2 need some sort of study such as wether or not they had antibiotics as kids.. Both my brother and i had had ear infections he also had his tonsils out i should have had mine out but never did.. We never get told to look after our gut at age 62 i got diagnosed during covid when we could not go out anywhere... I was diagnosed with epilepsy when i was 6 months old.. I think people on medications are more likely to be diagnosed..
I haven't even finished the video yet, but already know this is a HUGE BREAKTHROUGH. I've suspected complexity for a number of years now. It's even more complex than I imagined--Momo's blood sugar spikes with mashed potatoes but his wife's does not; yet with sweet potatoes it's the reverse. Wrap your mind around that! PS I wonder if I can go back to an old fave of white rice with tofu, soy sauce, and dabs of various dressings . . maybe some day. I always felt it was the combination I wanted; when I threw the rice out, the tofu eventually had to go with it.
Conceivably what you say about people's having different reactions to foods is true, although the glysemic (however it's spelled) index contains information that, I believe, provides much valuable guidance to people. But the male lecturer's claims, about knowing how to manipulate the microbiome, completely exceed what it is possible to do at this time. That is why Erika and Justin Sonnenburg recommend, eat fiber because it feeds and strengthens the micriobiota eat fermented foods because that increases microbiota diversity--and no other recommendation about the microbiota can be made at this time because not enough is known about how the bacteria and other components of the microbiota function.
See above comment. Some videos where people on a keto diet and/or just testing various foods. They test post meal comparing various foods and how it affects their BG levels. One fellow does the comparison with his wife eating the exact same items. IT can be done using a glucose meter without spending the money on a CGM. I hope that this helps.
I can't find this answer anywhere so here goes. If I eat only a whole food diet and fast for 17 hours every day, do I need to monitor my glucose levels? If I have an occasional grape, and my glucose spikes, is that such a bad thing?
Very interesting stuff. I am so interested in this. Can we tell from how we feel after eating which foods elevate our insulin too much? I feel like I must get it from drinking beer.
Well with beer drinking that could be the alcohol. But seriously I wore a cgm for a week or so and logged a very serious spike in glucose levels after eating fruit pies with custard. Maybe that’s fairly predictable but yeah I felt awful. Brain fog went to bed slept for a few hours. It was the next day that I looked at the graph to see a massive spike immediately followed by a massive fall in glucose ie hypoglycaemia. Apart from that I found potatoes are not good for me. In general I now restrict added sugar and limit carbohydrates in general.
So, this was interesting to watch. I’m confused why Momo says we were evolved to eat a lot of fruit as if that’s a fact, though. Has anyone read evidence of that, and if so can you share it?
It seems pretty simple, fruit is a natural part of nature. Humans evolved eating what nature provided. Fruit is full of nutrients that are beneficial to humans. The more colorful the the fruit the more it provides. People who try to scare us away from fruit do a huge disservice.
@@jeanne553 except it’s not simple. For example, you wouldn’t feed a lion a lot of fruit and expect it to do well. That’s why it’s important to look at the data of what we ate, and I never saw research suggesting we “ate a lot of fruit.” That’s why I’m asking
@@jeanne553 The fruit that our human ancestors ate was vastly different from the commercially bred fruits available now. Ancient fruits were smaller, more tart and only ripe for a few weeks per year depending on how close to the equator they grew. Nothing about our fruit sources today resemble what primitive humans consumed. In addition, the fructose in fruit is a biological signal to the human gut to begin to store fat and slow down metabolism in preparation for winter and food scarcity. In modern times that ‘winter’ never comes as food is abundantly available year round. Eating fruit in moderation during its season is probably fine for many
Are insulin receptors made from B6 and chromium in large part? What gets rid of B6? Copper toxicity and Oxalates. What gets rid of / antagonizes chromium? Lead and heavy metals. Basically we got to look at root causes on many levels. Does Molybdenum help regulate copper and selenium / sulfur help metallothianine remove heavy metals? Does EVERY disease start as a mineral deficiency? See Joel Wallach ND research.
can be a small contributing factor. however, the problem is primarily glucose overproduction in the liver. that pathway goes to insufficient short chain fatty acid production in the gut. also some vitamins like b12, b6,... are getting produced in the gut and uptake of certain nutrients like chromium needs a working gut, fueled by short chain fatty acid.
Have to monitor and watch your own health. That is the KEY. We make recommendations and look at the science, but only you know how your body is responding.
I have come across a book written by a naturapath .. The book is call the F balance written by Mark Van Etten on his fourth chapter he writes about eating for your blood group.. Do you know if there is any studies about eating for our blood group...
Very much of the food"chemistry" is utilised in upper parts of the food processing track and only "waste" products end up to the stool microbiom. Can you make your judgement based on waste?
I believe they're making educated guesses based on the microbiome excreted in waste. As Dr. Momo mentioned, they could tell with 80% accuracy whether or not a person has depression soley based on their waste.
eat all fruit and vegetables of the color spectrums but do not juice them. if you do make sure to add some of the fiber back that blew out the other end of your juicer. denatured foods are refined separated from fiber and alot higher in natural sugar hitting your blood causing un natural blood spike.
Yes your body makes glucose from Fat and Protein when you don't consume it so you don't actually need a lot of it in your diet. There are no essential carbohydrates. The benefit to eating carbs is normally the vitamins and minerals that come along with the carb.
There's something about fungal infections. Once you have that it doesn't matter what you eat or how much you exercise you won't be able to get below a certain number. The infection just holds it up. Once you get rid of that infection your blood sugar pops to normal walking to the milk section of the grocery store.
"Bacteria" is a plural noun ... like virusES. So the title of this talk should read "how gut bacteria affect blood sugar" ... this is basic grammar. I appreciate the health information!
Good AI work, from my knowledge of Ayurveda I can tell that there are 12 body types (dominating element) and there are 27 different types microbiome or may be 27×4= 108. I just hope the data supports my theory.
A very big WOW factor to what Momo had to say. To think my ancestors must have had something to do with my micro biome I guess. I came into the world from stem cell of mom and dad and from that must have influence from whence and where they came… All that must make a difference on micro biome evolution. Yes or No???
Spinach doesn't have K2, it has K1. K2 supplementation is highly recommended for everyone preferably 400 microgram daily, unless if you eat a couple of tablespoons of organic soy natto daily, that also gives about that amount of K2, plus lots of more benefits besides the K2, namely, nattokinase, baccillus subtilis, soluble and insoluble fibre, all essential amino acids and phyto-estrogen, which protects the body from the cancer enhancing effects of actual estrogen among others. And 4000 IU (100mcg) of D3 daily would also be highly recommended of course.
unless your gut microbiome does the fermentation and produce k2 for you. then you don't need to supplement because you carry your own pharmacy with you
@@stefanweilhartner4415 Excellent point. This brings to mind that perhaps we should be avoiding all supplementation for several months prior to a Viome test. We have provided so much complication into our bodies, even with amazing outfits like biome, What are they even looking at, who is in their natural state?? What is a natural state? :-)
this messes up the Levels software usefulness, ouch :) , as the gut biome study suggests that the number given by levels is just a number as ppl have different glucose response (and thus interpetation) based on biome and food combination it is also sad to watch her trying to cheerful of the study results, when in actuality these results level (pun intended) her software/app
Yeah, cutting whole carbs and increasing fat will drop your blood glucose reading, and eventually make you insulin resistant. Such insulin resistance is what causes the wild spikes when you consume whole carbs. These are easy solutions for people who are not disciplined enough to eat healthily. Eat a plant-based diet, mostly whole carbs and very little oil, and you will be healthy for life.
I follow the following diet in two words, REAL FOOD. See problem fixed. Gbomb is something I can remember. Oh, and I don’t want to even know how one collects a stool sample.
@@MOE-gm3si I know gluten is found in grains .. I was talking about eating for your blood group.. Potatoes should not be eaten when you have diabetes...
