Dr Longo has changed my life. I have done several FMD cycles with great results. Better yet, I am a strict user of the Longevity Diet. The Longevity Diet coupled with the Apple watch and the Chronometer app is excellent. Dr Longo is a very special person.
Any research on FMD in cancer patients without chemo Or immunotherapy?? Plus eating a “Whole Foods Plant Based diet Low in oil, salt and refined sugar? to extend life in human, slow cancer cachexia by slowing inflammation?? etc?
it s interesting that david sinclair and valter longo are two autorities on longevity studies and i recall they also worked togheter for a period of time but they diverge on intermitting fasting that is the main weapon, for what i understood, against aging and illness. actually seems all the world agree about intermitting fasting is a good thing, maybe what valter longo consider healthy is to eat normally all the time and periodically do heavy fasting, like his 5 days mimic diet, while sinclair consider that to be too difficult to do, and prefer alternate fasting and eating every day. anyway seems that a scientific truth hasn't been found yet on fasting
Intermittent fasting clinical studies showed it is benefiting human and animal health in profound ways..... its effects on autophagy, healthspan in various animal models, inflammation, brain, heart, bones, weight loss and maintenance, its healing effects on cancer, diabetes .....anecdotally Doctor David Sinclair also looked much younger compared with his chronological age...
@@ColettaDesign I don't think there are clear boundaries drawn for now and David Sinclair also takes synthetic drugs like rapamycin and metformin though I prefer to stay clear of such medications and their notorious side effects!
@@lenalim1220 Dr. Valter Lingo has 30 years of study and the statistics with living, long-lived and healthy people prove it, the question is: who can afford to doubt him, or rather, who has years of our lives to take the risk of proving that it’s wrong? 😬😳
I love Dr. Longo, he has warmth, compassion and humility, as well as passion and intelligence, what a rare combination! The last post was spot on, I could not agree more, he's a very special person! And, he's single..lol
Valter Longo does not look any younger, just like Sinclair, and they talk about not aging. I have watched them before and now.. geez, where is the credibility? we need some proof to believe..
Perhaps you could create Time Stamps for different subject matter within this discussion, that would help us. Another question would be if this fasting was equally impactful for lower weight (or even low-weight) healthy eating subjects - ?? THANKS.
What about if I have a 16 fasting window and eat eight hours but it’s all whole food plant-based am I still at high risk for the gall bladder problems and cancer and is the heart disease cholesterol and what not?
Have done 2 cycles of FMD but it has been a year. Gearing up to do another after my vacation. I like Dr Longo’s work, have one of his books. Actual science, data.
I've read Valter's book and it's very interesting and the data is very convincing. However, the day to day eating, if you don't want to lose weight, is very dull. I prefer a straight 72 hour water fast twice and year, but then a standard Mediterranean diet, with the carbs and cheese. One thing though, going by appearance, Valter has aged ten years in the last ten years, like the rest of us.
@@philo3936 Muslims fast is a dry not water fast, and it's not for seeking longevity but definitely for religious purposes, like the case of Jews, Christians or monk.
@@LiveLongPodcast The real boost for extended age has been Dr Thomas Levy's book "Stop America's #1 Killer . "Proof that the Origin of All Coronary Heart Disease is Clearly Reversible Arterial Scurvy. If you can meet the requirements don't be surprised at the results as I have. And I am not kidding!! If your familiar with the Coronary Artery Calcium score you would know that the medical community says that it is not reversible. But Dr. Levy expanding on Dr. Linus Paulings work has led me down the path of doing what was said couldn't be done. He's right cardiology has it wrong! And he's a cardiologist himself. My CAC Score went from 660 to 458 in 20 months by now it may be down to 400. Some people have halted progression and even 1 or 2% reversal in a year but 30%!!!!
It's interesting how much of what he says is the opposite of what other longevity researchers, such as Dr David Sinclair, recommend for optimum health span.
Sinclair is a self serving money hungry individual. Read up about the $700 million dollars he ripped off from GSK . Dr Longo is a fantastic human being. Sinclair is a cockroach
Dr. Valter Lingo has 30 years of study and the statistics with living, long-lived and healthy people prove it, the question is: who can afford to doubt him, or rather, who has years of our lives to take the risk of proving that it’s wrong? 😬😳
I wish there were somewhere I could find a list of the clinical trials that have been conducted and review the results for myself. It's frustrating that Prof Longo is unable to cite these himself in the interview.
Nestlé who owns mitopure are sued donnotage so they could not produce a much more inexpensive urolithina a supplement. And made them recall it. Really shitty
Ok, so is this a RECENT interview? What date? And what are the changes/advances of viewing that we should look out for here, that we have not seen before? (I am hearing diabetes mentioned . . . is this the crux of this interview?)
Thanks for your question. The interview was recorded in March 2023. Dr Longo discusses new developments in his research, relating to IGF-1/Laron syndrome, the FMD/cancer/other diseases and explains his vision of future healthcare. So it is about much more than diabetes. There are detailed show notes including a full transcript of the conversation at the Live Long and Master Aging website: www.llamapodcast.com/Valter-Longo2023/
You look really good and you're communicating much better than you did back then. I'm glad to see it. Dieting and fasting are very hard for me but I'm going to try and go on Naltrxone for awhile to stop drinking. I think that might make it easier. As previously mentioned, I have a lot of ambivalence about losing weight because of the complications it still brings back into my life. I only have about four grey hairs and for better or worse, am still considered beautiful by those who prefer voluptuous women, even at 69. The Titan disaster has got me very emotional and thinking about death and dying. I hope they didn't suffer. I think of you too, flying all over like you do. I'm afraid of planes and submarines, and complications but I might as well try again. I've heard good things about Naltrexone for Alcoholism.
My grandma who lived to be 91 yo said, "never skip breakfast. It's in the name, breaking the fast." And to my knowledge, my aunt who lived to 103 yo never skipped breakfast.
What is the biochemical effect of a 12 hours fast? For 16 or 18 hours of fasting there should be a little bit more autophagy what shall be an advantage for longevity. Is this wrong?
Five days fast would be equal to the regime and for fat adapted people's not that difficult. And you save money and time . He does point out about the bad info about eating 6 times per day. Also I think the word break fast or breakfast can be any time between 12 or 20 hours. Breakfast was designed to sell cereal and orange juice. I break my fast with liver or bacon or eggs or some sort of protein and fat. It means my ghrelin has got used to eating when I feel i am hungry. Keto dont do it he says. But it is helping people get off medication reverse diabetes and improve cardiovascular and mental health. You are not going to see established science support keto. It would do away with a lot of the need for different medical experts. Plus pharma would lose out. Sorry Valter I don't come from the med but my genetics came from farmers who lived long and good quality and healthy lives. So keto for me.
I think he takes a long term approach in his response. Although losing weight is super important for health so maybe there’s a good argument for keto on a temporary basis but… the research is solid that people who follow a low carb dietary regime have higher all cause mortality, presumably because of the increased consumption of animal protein and fat that takes the place of carbs.
not true..... if you put on a CGM.... you can find foods that after eating.....your body will be biohack to fasting..... I know I have been wearing a CGM and monitoring my food intake.
I don't understand, if there's only 100 of these little people, how can he tell that they don't get cancer or cardiovascular disease? Isn't that too small a sample to tell what their rates of a rare disease are?
The BIGGEST and MOST IMPORTANT longevity component by far is a strong social support system. I know people who eat terribly, used to smoke, still drink and are living (or have lived) to their 90s because they have so many friends and family.
I love the talk and don't doubt the science, but I would really like to know how the Prolon 5-day kit, which costs £199, compares to Dr Brooke Goldner's autoimmune protocol, which costs only a few pounds in groceries.
Question?? Is it OK to Fast or FMD if a person has shown some cancer cachexia- (muscle- adipose loss with fatigue) However maintains a normal BMI over One year time? And no increase in blood cancer marker?
Valter Longo looks 25 years younger than he is. Im guessing he follows his own protocols. I just ordered his 5 day FMD, hoping it’s not too difficult 😅
Very confusing. I was watching an interview that he did with dr Hayman, where he advocates for fasting …..?????? Has i Anything changed lately ?…. First fasting is great , now is not so great …. 😮
How long we can stay young ?! Till we get old , Herr professor . By the way , we can't stay anything . There's no status quo in nature . Only constant change
One of the BIG problems we have is that most healthcare spending is AUTOMATED through insurance premiums (employer+govt+employee). People are not going to see real, personal, financial benefits from a healthy lifestyle until we have healthcare options that DISCRIMINATE against unhealthy lifestyles. USA spends TWICE what other wealthy countries spend on healthcare are see worse outcomes and the existing system is not going to give up that income-stream without a fight.
The eminent Prof Valter Longo’s scientific critique on the Ketogenic diet seems a bit thin. The popularity of keto and reported health outcomes appear to be relatively solid…
what i would like to understand better is, how mtor works and how levels of hormones influence the effectiveness of the diet. what if an individual doesnt have elevated levels, may be they are even low. would it mean he she wont benefit form the low protein?
This is the second recent film I have seen by Dr Longo in which he criticises some diet and eating regimes programmes which have been very popular with people who want to be healthy and live a long time. The first was one in which he stated that people who skip breakfast do not live so long as people who eat it. For over a decade now the advice that breakfast is the '' most important meal of the day '' has been considered incorrect and out of date. Not so, says Longo. Today I watch this film and hear him argue that Ketogenic diets are not advised and will shorten life. As someone who has been doing intermittent fasting a lot since 2013 and also has done periods of keto, I am longing for some once and for all consensus on how to eat !
The reality is that the jury is still out on a lot of this stuff. I don’t know if you follow Peter Attia or David Sinclair. They both tend to be pretty anti-carb. David Sinclair skips breakfast and often eats only one meal a day. Longo looks very young for his age. But so does Sinclair. If I were going to place my bets I would bet on Longo. Nothing to extreme ….
There is also the issue of how our individual bodies respond to the different regimes. For example some people find a big rise in cholesterol from eating keto, but I found that after eating eggs sausages and bacon every morning for 6 months plus cheese ,cream etc I had my best ever cholesterol results. @@tombombadyl4535
You won't find it. There is no one way to eat. People are different. The longest-lived woman in history, which Longo refers to often, Mdm Calment who died at 122, ate three eggs a day and picked up smoking in her late 70's. But find some average American and these things might kill them. You have to find what works for YOU. There are websites that use your DNA test results to tell you about your ideal fitness, and diet. Look them up. See what they have to say. Try to get as personalized as possible. In the meantime, test yourself through local labs, measure your own glucose, do elimination diets, and so on. Once you find the sweet spot for YOU, it won't matter what any doctor says. That being said, Blue Zones are a good example of what healthy living looks like for *groups.* Check them out for ideas, because if you're from any of those regions, they might just be able to show you the most natural diet for your heritage. This is important. You've probably heard it said to eat like your grandparents...well, that's good advice. That's before processed junk. If you're genetically from Germany, potatoes might be better for you than rice...for example. As for him criticizing skipping breakfast, he did find more gallstones in people skipping breakfast. This is logical because excess bile acids in the gallbladder with nothing to digest for six hours have got to go somewhere. So *if* there's excess cholesterol in that bile it's going to form stones. Does that mean Sinclair is lying or wrong? NO. It means Sinclair - who is in excellent shape - isn't likely to have high cholesterol in his bile! See how that works? Longo is talking about average people, not David Sinclair. Also, ketogenic diets the way average people do them are disasters. People think eating lots of butter, fatty meats, and other god-awful fake keto foods is the way to go. As if it were a high-protein diet. Well, you don't have to be a rocket scientist to see the potential problems here. Of course, he's not going to recommend it! Keto means high fat, not high protein. I have done them too, and it shoots my LDL through the roof. Then I learned I could do vegan keto and guess what? no LDL problems because I don't consume saturated fat. Duh! People are different and most people are uneducated. Do the math. Good luck!
There are so many good and salient points here yet the English is so hard to follow that it’s difficult to understand which direction he is speaking or at all what he is saying ? The interviewer helped once or twice yet it left so much of interview totally Confusing Without going all his research it’s too bad to not be able to glean more It may be most me But as a dr that understands the topic already I can’t be the only one I will listen to the whole interview again anyhow
Sorry you found the interview difficult to follow. It is indeed a complex topic with many nuances that require some background knowledge. This is the latest in a series of interviews with Dr. Longo. Two of our previous conversations are linked here - they may help to fill in some of the gaps. Hopefully you will find them useful. Thank you for listening/watching. Fasting for long term health benefits (March 7, 2017) ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-sP4oL7bjtZc.html Living to 120 on a science-based diet (January 7, 2018) ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-Nz0VhAp3NkY.html
@@LiveLongPodcastthank you for interviewing Dr Longo. He is, for sure, an interesting fellow. I think the more you listen to him, the easier it is to understand him.
Valter Longo is partially not fully correct in this statement 37:50 min . Because legumes are high in Leucine, which is good for muscle, bone, organs. But low in Methionine which is needed for the immune system. Restriction of Methionine for some time is a hormetic stressor triggering positive adaptive responses probably also for longevity.
Until you're 40 years old, then you're middle aged. Mitigating the inexorable march towards old age and death cannot be stopped. Avoiding the pain and decrepitude along the way is not staying young. The healthiest old person knows they are old and feel that way. Start calling it what it is.
If you want to age and die as soon as possible, yes meat is the answer. If you want to live a long and a healthy lifestyle, vegetarianism is the only way. Period.
@@Tiborqiusz but MEAT has all vitamins, minerals and amino acids we need. So, why should I eat man made plants? Do you know that there are not edible plants for human in nature. Do you know who INVENTED 🥦 broccoli? You brain can’t build new neurons without MEAT, do you know that?
@@longevitycoach1573 Man, you have absolutely no clue what you are talking about. No offense. I'm a vegetarian from 13 years now, i experienced everything when it comes to food. Meat is the most acidic and most dangerous poison you can put into your body. It's pure trash! Human beings were created to eat fruits, vegetables and seeds. That is if you want to keep a pure body. Not to mention a pure soul, as you eat the slaughtered and tortured animal's flesh, so you basically eat dark rotten energy. All the vitamins and minerals that you need, can be found in fruits, vegetables, seeds and grains. Clearly your knowledge is limited on this part, otherwise you wouldn't try to push the meat poison agenda on others. There is no good health and long life with eating meat, and definitely there's no spiritual evolution as long as you put that trash in your body, which suppose to be the temple of God. Most diseases and health problems comes from eating meat. There is no worst food on this planet! You better off eating plastic, and still would be better than eating meat.
@@mnayak9348 Because they're more spiritual, and understand life better, than meat eaters. I rather be lonely and healthier, than sacrifice my health just to be surrounded by people.
