How nanoparticles could change the way we treat cancer | Joy Wolfram

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Ninety-nine percent of cancer drugs never make it to tumors, getting washed out of the body before they have time to do their job. How can we better deliver life-saving drugs? Cancer researcher Joy Wolfram shares cutting-edge medical research into nanoparticles -- tiny particles that could be used to deliver drugs accurately to tumors -- and explains how they could keep drugs in the body longer to attack malignant cells.
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2 окт 2024

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Комментарии : 189

@cosmic_snot 4 года назад

TED, more of science vids like this one, please.

@joywolframlab4939 4 года назад

Thank you, Misha S

@bracholi 4 года назад

Holy crap, TED hosted an actual scientific/medical talk

@FarhanAli-qo9we 4 года назад

ikr. I know other people are more arts-based, but I don't really want any more dance videos in my feed lol

@perfectimperfectness3519 4 года назад

Farhan Ali 😆

@Biomeducated 4 года назад

Thumbs up for strong women in science! Great research!

@jasonvolta3657 3 года назад

@@Biomeducated just about time, as Elisabeth Holmes is getting hammered.

@Biomeducated 3 года назад

@@jasonvolta3657 Haha! Theranos pyramid scheme :D

@patscat5099 4 года назад

TED actually hosting a vid about science again? That's why I subbed months ago, but never got since.

@christina-mz1lp 4 года назад

Same, I love science

@lamidikolawole218 4 года назад

I actually got tired of the philosophy and motivational talk.

@ruben307 4 года назад

there have been a few maybe you missed them

@rickyricardo6211 4 года назад

Sorry for you're loss..Thats is extraordinary..Ted is so enlightening and educating keep feeding me please..🙏..

@joywolframlab4939 4 года назад

Thank you, Danokbp Styles

@rickyricardo6211 4 года назад

Thank you🙏😊🌻

@rickyricardo6211 4 года назад

@@joywolframlab4939 Thank you🙏

@jamsheeddevotee7588 4 года назад

I fully fathom that $100 billion is a ton of money, but we've been spending 6.6 times that annually on the military which makes seem as though it's not that much of a priority.

@MichaelBerthelsen 4 года назад

And considering the exposures causing cancer in veterans, it WOULD be a good thing even for the military and the VA...!

@ПавелНауменков-л4р 4 года назад

My father died from the liver cancer 1 year ago. I miss him so much and i am sorry for your loss.

@joywolframlab4939 4 года назад

Thank you. I am sorry for your loss.

@nahulseyon54 4 года назад

@@joywolframlab4939 I'm sorry for your loss. My grandma died of skin cancer. I HATE CANCER... My favorite old man in my favorite village died of throat cancer. One of my well wishers died of intestinal cancer. One of my favorite actors Chadwick Boseman died of Colon Cancer😣😢😭...

@osaslinda276 3 года назад

Am really grateful for what Dr Manbela did for me,. for the past four(4) years now have been suffering from hepatitis B, have use different means and been taking drugs until i came across Dr manbela who helped me with his herbal medicine., i contacted him and told him everything he prepare a herbal medicine for me and send to me here which i receive in the next 4 working days,. i take it as he told me and today am happy have been cured. you can also contact him told through his email drmanbelaherbalhome@gmail.com or through his whatsapp number +12313105906,or through his web:, drmanbelaspelltemple.webs.com , he aslo has cure for other deadly diseases like cancer, Hiv/Aids., Herpes,Diabetes,Urinary treat infection.,impotence,Infertility,Diarrhea,Asthma,.,. bed wetting e.t.c. thanks Dr Manbela may God almighty bless you!.,

@shifanaibrahim3346 Год назад

@@joywolframlab4939 hi mam I'm a graduate from nanotechnology i need to work with you mam

@TOADALLY123 4 года назад

1:31 I think that’s a bit of a exaggeration. treatment and medicine for cancer is a lot better than it used to be. For most of human history up until 30 years ago almost any kind of cancer was pretty much a death sentence and you were dead within 6 months to a year. Today There’s a lot of cancers if you catch early enough you can live beyond 5 years to 10 years like prostrate, Hodgkin’s lymphoma, thyroid, throat cancer. Robert De Niro, micheal c hall, Elton John, Ronnie Wood and Ben stiller and many more people who we all know have had cancer beat it. If they had gotten it a couple decades ago they would of been dead in a year. Obviously we still have a long way to go in terms of treating and curing cancer and doctors need to get better at treating it because a lot of people do die from cancer still but it is better than it used to be. I do agree we haven’t made really any progress at treating really aggressive cancers like brain, liver or pancreatic cancer. Those cancers are basically a death sentence. But hopefully that won’t be the case soon.

@joywolframlab4939 4 года назад

True. Thank you for clarifying.

@jasonvolta3657 3 года назад

I daresay that up to 30 years ago cancer was much less widespread. Its a modern day disease.

@pyschologygeek 4 года назад

Finally some is talking about this

@jasonvolta3657 3 года назад

yeah, they got the replacement for Elisabeth Holmes.

@bkb04g 4 года назад

What is this lady’s accent? I cannot place it. But what I do know is that she is doing God’s work. And that humanity will be better off having Joy in our force.

@justinaltena 4 года назад

She is Finnish

@Dylan-zg2jl 4 года назад

@@justinaltena Don't be silly, she has practically her whole career ahead of her

@ohammouda 4 года назад

@@Dylan-zg2jl Hahahaha that was a good one

@Biomeducated 4 года назад

@@ohammouda It is! :D

@joywolframlab4939 4 года назад

Thank you, Bryan Burns

@smoothkid765 4 года назад

A worthy TED lecture.

@joywolframlab4939 4 года назад

Thank you, Randal Smith

@etorawa9367 4 года назад

She's from Northern Florida? She dont even have a Southern accent! Yes, I am being facetious 🙂

@MichaelBerthelsen 4 года назад

Had to look it up to be sure, I was right. She sounded Finnish to me immediately, and she did grow up in Finland and did her Master's in Helsinki.😅 Which is to say, Helsinki is in Southern Finland, so... Maybe she DOES have a 'Southern' accent. Just wrong country and continent...😜😅

@perfectimperfectness3519 4 года назад

Michael Berthelsen 😆

@C_Mor_Rocks 4 года назад

My fiancé was just diagnosed with stage 4 colon cancer. She is only 30 years old and is an audiologist, has been otherwise extremely healthy, and is eligible for any experimental treatment... unfortunately the doctors have told us there is no cure and she will be on chemo the rest of her life. I call BS on all this talk of new medical breakthroughs when obviously nothing is really being done. It’s all just people talking about things they can’t do

@SanguineThor 4 года назад

Don't be discouraged, science keeps moving. I hope that your wife will be well

@godhell8039 4 года назад

I am moved. ❤️

@revanveran5325 4 года назад

My immediate thought is what are the drawbacks and how do we ensure no lasting harm comes from the nanoparticles? On the other hand, if it avoids their death, it should be worth it.

@fionafiona1146 4 года назад

Fulleren (C60) is quite safe, only cancer cells being aggressive enough to brake it open but all are held to that standard.

@Surtac100 4 года назад

If the nano particles are to big to get washed out do they stay in your body forever?

@MichaelBerthelsen 4 года назад

@@Surtac100 It could be possible to insert a self-destruct system, so they break down after a certain amount of time, or even with high-frequency radio waves or the like.

@MetallicReg 4 года назад

Surtac100 They get more time - they are less bioactive. But your body can handle even the least bioactive things with time. This is why your body can even remove tattoos paint particles through your lymph nodes.

@revanveran5325 4 года назад

@@MetallicReg Personally I hate that idea, it feels like something that could be wraponized. Anyways, what they were saying was that it does EVENTUALLY leave the body, just way slower, and the liver and things don't destroy them. In my opinion however, if they didn't leave, so long as they don't kill me, and they stay in my body, having permanent medicine against cancer in my bloodstream would be amazing.

@FredoCorleone 4 года назад

Is it me or all this was so confusing? What's the mechanism with which the nanoparticles should destroy the tumor?

@britneyvolckaert9281 4 года назад

Typically nanoparticles don't destroy the tumor themselves, rather they help increase the efficacy of the cancer drug. They can serve as carriers (firetrucks) that help target the tumor cells while avoiding damage to healthy cells. They can be designed so that they can circulate relatively undetected from our immune system so the cancer drug has more time to do its job. Some nanoparticles, like metal/gold nanoparticles can be used in thermal therapy where you can irradiate it with a certain wavelength of light such they heat up and either kill the cell or just weaken them (makes them more reactive to the cancer drug). Very simply, the nanoparticles are the packaging, and the cancer drug inside is what destroys the tumor at the end of the day. (This is all just my understanding, I could be wrong)

@TheFrygar 4 года назад

"How X COULD treat cancer" is the name of countless TED talks over the years, almost none of which have actually provided any real breakthrough or benefit to any actual cancer patients. This industry is rife with ideas, but barren of anything other than "more surgery, more drugs that may not work" in implementation. I applaud the work being done, but am not at all optimistic that any of this will do anything for an actual cancer patient within the next 20 years.

@liketobi178 4 года назад

I thought the same thing. I have heard about so many "breakthroughs" but nothing has happened yet. I don't know if this is just a rumor, but why would the pharma industry even want a cure against cancer. They earn billions with existing drugs.

@teasipper6106 4 года назад

It really depends on the cancer. Breast cancer now has a 5 year survival rate of 90% and a 10 year survival rate at 83%. Glioblastoma has 5 year survival rate of effectively 0% Cancer is a catch all term for several dozen major categories covering hundreds of different diseases with a literal infinite number of possible variants. There is more genetic diversity within the cancer cells of a single stage 4 cancer patient than there is in all the HIV viruses in the world. Progress is being made, but this problem is so hard, we will be fighting this broad category of diseases for another century.

@TheFrygar 4 года назад

@@teasipper6106 Sure, all I said is that the "breakthrough" TED talks you see which promise new treatments for large numbers of patients have never panned out, or only helped a tiny fraction of a fraction, much less than implied by the talks.

@archivez101 4 года назад

Pollen Applebee big pharma already has a cure for cancer. But it’s not getting out since they’re making big money.

@Dreadboi1990 Год назад

Dr Hadiyah Nicole Green pioneered the research and came up with the idea method of using nano particles in her graduate program. She's a physicist and a Hebrew woman.

@kieranjameswatkins25 4 года назад

Incredible stuff..

@bilgilibilgisiz3879 4 года назад

You need to learn "neslican tay"s life.

@chuyang6861 4 года назад

Finally, a topic on medicinal drug use

@easysimplecuisinefarmer 4 года назад

I am so sorry for your friend. She’s so young. Thanks for your research on nanoparticles to fight cancer. We need your help.

@joywolframlab4939 4 года назад

Thank you.

@easysimplecuisinefarmer 4 года назад

With great pleasure.

@shannonwilliams7743 Год назад

Discovery of this process made by Dr. Hadiyah-Nicole Green.

@adarshkv511 4 года назад

And they end up in tumor

@mayanksingh5214 4 года назад

Nice video. I am from india and i really likes your videos.

@rennis4471 4 года назад

👋👋 Hi from the United States

@mayanksingh5214 4 года назад

@@rennis4471 hi rennis

@C_Mor_Rocks 4 года назад

@agugloriankechi4616 2 года назад

Thank you Dr Ogoh on RU-vid for being the Reason I am Smiling today, I still can believe I am finally Cured from my Cancer Disease , Keep up the good Work doctor. 👍

@DinoNucci 4 года назад

BUT do they take Glock mags?

@Topnotchhealth 2 года назад

Wonderful presentation. However, the idea behind loading chemotherapy into nanoparticles has nothing to do with the chemo drug size or being washed away out of the body when administered in it traditional form. A typical chemo drug infact stays in the body for over 2 days. The idea of a chemotherapy loaded nanoparticle is to overcome side effects like hair loss, nausea and vomiting associated with chemo drugs as chemo drugs have off target effects; they tend to attack normal cells in a bid to elicit their therapeutic effects.

@globalvillage423 4 года назад

There has already been a talk about using body's own immune system to destroy cancer.

@ifyoudontfailyouarenoteven6210 4 года назад

It's slightly different situation, this is more about "fooling" immune system to stop it from attacking something which is recognized as foreign by default. Using own immune system to destroy cancer usually involves modified T-cells harvested from the patient or close relative (please check a documentary called "War in the blood" hopefully is still available on yt. Here we rather have some sort of "encapsulation" for anti-cancer drugs, to help them being delivered via demanding body "piping" into the hostile, immunosupresive tumor environment.

@mohammedkazeem56 2 года назад

My mom is totally free from Cancer after her repeated test prove Negative.its my great pleasure to thank you Dr emuakhe on channels for your Great Herbs Sr and keep Saving life doc..

@scoobameru2458 10 месяцев назад

Four Years Later, Where Are We ?

@ivyvictoria6783 Год назад

From watching this video 3yr ago to seeing the first ever human trials in aggressive brain cancers now…it’s crazy

@worldfoods6432 4 года назад

Love this 💜💜💜

@intotheunknown8100 4 года назад

Finally the Cancer have some Answer!

@mizukaku09 4 года назад

What is the name of that biological nanoparticles found in human body?

@rennis4471 4 года назад

Great question I wanna know too

@joywolframlab4939 4 года назад

Extracellular vesicles

@pauldjerassi620 4 года назад

I think using the Host nano particles is the way to go ie tailor made treatments pre market clinical trials will fast track the 12 year wait by the FDA,Thank you for a very interesting video,Djerassi.

@Lunareon 4 года назад

This method still doesn't solve the main problem of current chemotherapy, which is the problem of cancer drugs destroying both healthy and cancer cells. Circulating the drugs in the body for a longer time also means they will cause more damage to healthy cells. Nanoparticles could be part of the solution, yes, if paired with some kind of a mechanism which directs them to the tumor and cancer cells.

@liamcarey6827 3 года назад

current nanoparticle systems have controlled release mechanisms in place, for example the pH and temperature inside a tumour is far higher than the rest of the human body, so the nanoparticles have been engineered so that they do not deteriorate and release the drugs until that specific change in their environment is detected.

@aartigaykwad 2 года назад

Such a good explanation 👍

@gameglimpses8861 4 года назад

Wow !

@nutankasera259 4 года назад

Nice

@MrMiniash 4 года назад

Fit

@docp667 Год назад

Nobody failed anybody

@Mountainmikee 4 года назад

420 likes... nice

@declanmckeown323 Год назад

quite informative

@ivanandreevich8568 4 года назад

Therein lies a major assumption that a funeral is worse than a wedding.

@aguywithglass8340 3 года назад

Can anyone provide me with the mechanism of the nanoparticles in this case?

@ranam 4 года назад

Reebaca drama was my plan for my talk on cancer treatment that I day dream every day of giving tedx talks but she took my drama but I also don't have the magic drug

@zidan2019 2 года назад

9:51 12 years? This people take their time!

@whitehanzo 4 года назад

nanoparticles? are you saying that now we can create Gundam 00?

@mehwishrehman9787 2 года назад

wow

@mephy72 2 года назад

what is the anti-malaria drug?

@zahidkhan5532 3 года назад

very beautifully explained.....neverever seen such a eye-opener video

@mlvesr 4 года назад

The science we do seed the world with perpectives different.

@TheKevinpascal100 4 года назад

🙏🏼

@Fiona2023 3 года назад

4:50 nanoparticles circulate longer

@hermelaalemneh9947 Год назад

This is the best!!!

@imspidermannomore 4 года назад

she's 13 from House MD, isn't she

@abhishekpanwar1455 4 года назад

Would someone like to talk with me, i feel lonely and i am not doing great in life. Also i lost my father in 2017 with cancer

@jaymarcum1174 4 года назад

Good Morning, Let me pray for you , “ Father in Jesus’s name please comfort abhishek help him in his loneliness give him friend to support him , please let him know that you love him and that we both have a Heavenly Father who knows the difficulties we are going through and is with us . Bless Him with who you are,” Jay

@babciab1721 4 года назад

abhishek panwar you will be ok- lots of people are thinking about you

@jmer9126 4 года назад

Would that old drug be Quinine?

@dhimanroy1671 4 года назад

Great one! Thanks ma'am

@HeadBangaxxx 4 года назад

How about we switch from treating cancer to Curing cancer just a thought

@heatherbaldwin8293 4 года назад

Now there's a great idea. Or maybe preventing cancer. But they dont talk about that because cancer is a multi billion dollar business

@HeadBangaxxx 4 года назад

@lamingmeout Yes nd no, there are proven Universal cures depending on the stage of your Cancer... Universally speaking in the broad aspect of things, cancer occurs in the body when the electric frequency "Hertz" in your body is low. Which can be caused by many outside influences. A customized hollistic wellness plan, based on your bodies' chemistry can raise your Cellular Frequency reversing the rogue cells or "Cancer cells" mission in the body...Now, cancer in later stages your chances are slim to nun for recovery..But i believe that preventative measures, taken by everyone is the best way to treat cancer .

@astrim1262 4 года назад

*big brain time*

@xkl-physics7287 4 года назад

Fullerenes

@ali.faris. 4 года назад

أرجو ترجمة الفيديو إلى اللغة العربية

@ali.faris. 4 года назад

@Miox Lvax شكرا جزيلا جزيلا.

@MPTran-pz1gm 4 года назад

Great job!!!

@lanceflanagan 4 года назад

The importance of this subject isn't lost on me but I must say, she's ridiculously attractive.

@jarkkoaitti287 4 года назад

"i failed", "my lab". i wonder if her underlings want to give a cancer to her :)

@isaactfa 4 года назад

Nanomachines, son.

@leonardsollaku1779 4 года назад

particles mate quite diferent

@heatherbaldwin8293 4 года назад

How about we eat right

@angelgreen2602 4 года назад

Do you think you can really do it because I watched it 8 times the smashing and blasting I'll tell you right now if you do not get rid of the pink and gold it will happen again and again and again the new cannot mask it you really have to smash them into fine particles I'm sorry and God forgive me but that is the truth and now we must decide who is humanized! and who is de-humanzed! God have mercy DO YOU THINK YOU CAN HOLD IT BACK THIS TIME?? If you must get with blue and introduce the green what do you think's going to eventually HAPPENE if you want me to show you the decisive element just ask me! "💛🗡️" ¥ (?) Do you want me to do it!!👽💙 Are you truly prepared to do it for the better of all

@IgorGabrielan 4 года назад

oncology.ai

@sabricr 4 года назад

Search Louise Hay, she cured her own cancer with no drugs but pure energy. Joy didn't fail, just proves science and medicine can reach a certain limit.

@Surtac100 4 года назад

How about changing to the Gerson therapy!

@harrisonrutledge5 4 года назад

Propoganda

@jamesbuck3984 4 года назад

First?

@ammarif618 4 года назад

I'm the half

@niteshkumarpatel 4 года назад

The host is really hot.

@MichaelBerthelsen 4 года назад

Why am I seeing quack healer adverts on a TED talk...?😒😠

@lkuc06 4 года назад

Why do i get the feeling Joy made up the story at the start🤔 ...sounds like one of those reel in the crowd with a softener and then hit them with the product ur trying to sell.