You can create different GPOs and assign them to those OUs. Additionally you could use item level targeting to display (or not display) a mapped drive to certain users.
@@thecybersecuritymindset thank you for your reply... Yes..i tried to use item level targeting...but it didnt work!..plz make a toturial about this...😢😢😢..another thing....users who have no permission over a folder shoukd not be able to see it at all. How to accomplish this??😢😧