Have a pretty rare blood mutation ITGA2B genetic mutation that causes me not to clot, have less platelets and ineffective platelets. Took 38yr to find that it wasn't ITP. They kept trying to treat me but it wasn't working
@@hermanmcleod5182But that's not what was meant. You completely misunderstood the comment you responded to. The commentor is giving respect to those who donated their bodies to science.
When I was 12 years old I was diagnosed with Aplastic Anemia which is a disease where your bone marrow doesn't produce enough blood cells. We found out because my mom had notices huge bruises all over my body that seemingly had no explanation. I got a bone marrow transplant which basically cured me. Fun fact about my experience though. The time between my diagnosis and my bone marrow transplant (and for a bit after it while my new bone marrow settled in) I got a ton of blood transfusions. The platelet ones were fine other than the hives I would get during them but the double red transfusions I would get also came with a huge increase in my iron levels. I could literally taste the iron while getting the transfusion. The body doesn't have any fast methods for getting rid of excess iron so my doctors had me come in a few years later to have monthly phlebotomies to remove a pint of blood each time (I like to joke that it's modern day blood letting). They would take the blood and then give me an equivalent amount of saline back. This reduces iron levels because it forces your body to make more hemoglobin than normal which draws down the iron stored in your liver. My iron level is still on the high end but within the acceptable range.
Another unrelated fun fact about blood is that pee is blood. This freaks people out even though, when you think about it for a second, it's pretty obvious, but your kidneys, bladder, and urethra are not in any way directly connected to your digestive system. Your kidneys are basically coffee filters for your blood, separating excess water and waste products and sending them to your bladder.
@@anubis7617 correct. One of the things I asked my doctors during my recovery was if I could donate blood because I had taken so much I wanted to give back. They told me that I was unable to. My dad gave a lot of blood though and he signed up to be a potential bone marrow donor.
This video is insane. How a human body produces the necessary things precisely, efficiently and timely, like a clockwork. And we abuse such a machine by drinking, smoking and killing. Jones, your videos need to be a part of the school curriculum irrespective of the syllabi.
Thank you for the breakdown of all the different functions of all the blood components, rather than the basic “it carries oxygen and made in the marrow”. I think a good follow up video to this would be to discuss the lymphatic system.
Haematopoeisis can be: Erythropoeisis : Formation of RBC Leukopoeisis : Formation of WBC Thrombopoesis : Formation of platelets All three occur in red bone marrow by a pleuripotent haematopoeitic stem cell which give rise to erythroid series, myeloid series & megakaryoid series which ultimately form RBC, WBC & platelets respectively. All in all the various cell stages & processes of haemopoeisis is very interesting! 😅
@@JiveDadson Have you tried Phlebotomy for platelets reduction? What about platelets targeting drugs like Anagrelide? What about combination therapy: Hydroxyurea + Erythropoetin (Darbepoetin) + Colony Stimulating Factor? If nothing else work are you open to more riskier options like Busulfan, Interferon alpha or Ruxolitinib? Though these drugs are essentially bone marrow suppressors but with supplementation therapies like Blood transfusion, Erythropoetin therapy & CSF therapy RBC & WBC production should be optimal....? Please contact your Haematoncologist before taking any action!
I am so impressed by the way you simplify everything for laymen. I aim to be able to explain everything to patients in the way you do!! Please keep doing what you’re doing, I am so glad you are making information like this accessible to everyone and I think it is so important!!!!
Even your salivary gland produce saliva by filtering plasma! This is essential for tasting the food. Your plasma has some concentration of salt, sugars & you label your food being more salty or more sugary as your body is accustomed to the salts & sugar level in the blood so the brain essentially compare the exogenous & endogenous concentration of salt or sugar to taste the food!
Pls can you make a video talking about sickle cell anemia disease and how to manage or treat the condition, and essential drugs that can help boost the production of more normal red blood cells etc. Thank you
I am a physical therapist and personal trainer and I love watching your videos. I see people of all ages get healthy before my eyes by inspiring and educating them to understand how truly amazing the human body is, and wonderfully it adapts to nutrition and exercise!
I’m a nurse on a haematology ward. Learnt new stuff thanks to this video :) It is an amazing part of the body, and I love my job and all the patients 🥰
I'm 65 and most of my health related issues come from poor oral hygine when younger. Of course, my dental hyginist suggested going with OralB, but I should try the brush suggested here. I've watched many (a lot) of your videos, along with your collegue, and I'm amazed of the human body dontations. Awesome work. Thanks.
A tangent topic might be blood/platelet/plasma donations and why a recipient might need them other than the obvious loss of blood. I donate platelets and plasma regularly and on ~6 occasions have been called by the blood bank needing an emergency platelet donation from me for someone that I'm a good match for. Once I was told there were only 3 donors in the Dallas/Fort Worth area (close to 7 million people) that matched someone and I was the only still-active donor. I'd love to see more detail on how all this works.
One of my favorite sayings we have working in surgery is “all bleeding stops eventually”. Facts! I’m glad you mentioned anemia. It’s important to remember that long term use of certain antibiotics will cause a suppression of red blood cells that are being produced by the bone marrow. Great information as usual! ❤️💪🏼😎👍🏼❤️
Can you please do a video on the different types of anemia and how anemia affects the body? I'm recently diagnosed as iron deficient anemic and I'm trying to learn and understand as much as I can.
I got anemic with 4 hemoglobin almost die, for take too much ibuprofen and naproxeno without omeoprazol, two ulcers one in the stomach another un duodeno, internal bleeding during months just now the day before for vomit blood and the next day too and go to the hospital, also low inmune system during last six months.....after one week in the hospital 4 blood transfusion, iron and B12 and two endoscopy I'm recovering.... so yes blood is important
Praying for you now, friend!!!!!! Just always know, you always got someone who’s praying for you. If ever you’re needed some extra, just circle back to this comment and just say you could use some prayers. I’ll always do that for you!
i was just recently worrying assuming i didn't have enough blood in my body and what a timing, IoHA came out with a relevant and doubt clearing video. i always find your video informative, helpful with so much of little detailing.
@@socialmediaoutcast True. actually i didn't noticed it for very long until these recent couple of years when one of my teacher mentioned about this 'Creepy' fact. and i was amazed how true it is.
This is awesome! One thing you guys should change is your slide at the 9:50 mark. You said white blood cells are "leukocytes" - which is correct - but your slide says "lymphocyte" which is a specific type of leukocyte.
A very recent meta-study indicates that elevated levels of platelets alone is not correlated with stroke. That's probably because the platelets need enzymes called "sticky factors" to glue them together to form clots.
I find it strange that it isn't obvious to everyone that the reason poor oral health is so heavily associated with poor heart health, is because carbohydrates cause them both, as well as Diabetes 2 and 3.
i got an exam of this in a week, great video. i didnt know there was that much Hb in each eritrocyte but yeah now thinking about it the nornal value in a male is 13-16 g/dl so kind of makes sense
Dear Dr. it is with great respect that I wish to say thank you for your invaluable tutorials about human anatomy. The way you present any layman can understand very well enabling to make meaningful adaptations for lifestyle and healthy longevity. God Bless You... 🙏🏻🙏🏻🙏🏻🙏🏻💐💐💐💐❤❤❤❤
I love your videos so much, your energy and happiness about anatomy makes me happy and easier to digest this information. I’m not in school or anything but I can’t help but to continue to watch and support.
I thoroughly enjoy this channel which I discovered today. Your previous video was sponsored by grammarly …. In this video you had a typo around 4:45… again… I’m a fan of this channel, thanks for the information
Yes, it’s true that one should take care of one’s health and not abuse it yet you cannot help if others attack assault harm you. I am so fond of exercising a natural outlet for my energies yet because of my neck condition I cannot fully exercise at least not my upper body
Can you do a video on Osteoclasts as well as Odontoclasts, and include how each works regarding resorption? I was just at the dentist yesterday and, thankfully for me and my family history, I was blessed with great teeth! This visit though, my dentist noted that my rear left lower molar is likely suffering from external resorption. Well me being an engineer, there began my last many hours of research on the topic. Yet I find it so fascinating as well as difficult to follow, on how the whole process works, as well as when it no longer works as designed and starts affecting structures in a negative manner, like now in my case! Thank you!!!!
I'm happy to see another video that's not a "bro workout fitness video". I always liked the older videos that were more of an anatomy and physiology lesson as opposed to the ones obviously focused on men who are into fitness and working out. Can we keep the A&P (and patho) videos coming?
Please do a video on how malaria parasites effect our bodies and the complications that can arise . Is it true that you can develop immunity to malaria and dengue fever? Thank you brilliant video’s
What's more crazy is how various people over the last century have figured out how much diseases and conditions can be determined with certainty just looking at somebody's blood.
Laboratory Science is definitely fascinating!! If you didn't know, you can go to school for this and make decent money depending on facility and cost of living in your area 😃
Excellent video. I’m surprised though how there wasn’t any mention of DNA whilst talking about blood & its cells. I’d definitely like a deeper dive. My spouse was 12/13yrs old when diagnosed with factor five leiden. Has dealt with multiple venous stasis ulcers & a stroke all while still on warfarin. So know a good deal about that, though would be a good video I think for everyone else. I am more curious about a most recent diagnosis of APLS. All I know is it has to do with antibodies & the immune system which was touched on briefly in this video, though I think needs a deeper video. I’d appreciate it as the doctor who talked to us about it made it quite confusing & you tend to explain things so eloquently, yet easily understandable.
I’m a female and I’ve struggling with anemia pretty much all my life. I have a very heavy menstrual cycle so I’m always taking iron. Which gives me diarrhea in turn and stomach pain. Needless is to say, I don’t like it.
I have a genetic blood disorder called Beta Thalassaemia Major which means I don’t produce one of the two types of haemoglobin. I was diagnosed as a baby and have blood transfusions every 3-4 weeks for life. I never underestimate the generosity of those who donate blood that allows me to live. If you’ve ever donated blood - thank you!!!! 🫶🏽🫶🏽🫶🏽🫶🏽🫶🏽
2:00 Regulation 3:55 Denser than water 6:55 *How body makes blood* 9:30 Production of 2-3M red blood cells per second 12:30 Anemia 13:20 White blood cells
This is really good content. I assume everything here to be correct, and as someone who has only an interest in biology (not a student or biologist) it's really nice to have this information, delivered in the way you do. Well done & thank you!
@institute of human anatomy your all videos are super informative. Thanks a lot... ❤❤ Please make a video on Sciatica pain & possible exercises for this pain.
This is amazing. The geometry is something you can never convey properly. You couldn't even recreate it in 3D let alone a 2D video. How it folds in on itself infinitely and comes out of nothing but also responds to your thoughts? I can't even explain it with words 😂
Red blood cells are indeed amazing but I'm mind blown by now knowing that there are different types of white blood cells, I look forward to that video!
For over a dozen years, I have had a condition called polycythemia vera. That means I have a cancer that causes my bone marrow to make _too many_ blood cells. Untreated, it is fatal. In the words of Redd Foxx, "I ain't never had enough of anything yet, but I've had too much."
Would you in a future video elaborate on a thing runners would experience called foot strike hemolyses? Breaking the red blood cell and via the kidneys ending up in the bladder
Hi Jon. Love the channel. Was wondering if you can do some videos on common surgical procedures and what muscles are cut, bones broken and the tools used etc to perform them. Common ops are heart surgery, knee reconstruction, c section, hip replacement and my favourite, compartmental fracture, as it happened to me when I was 10.
