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Hydrogenation Reaction 

Named Reactions in Organic Chemistry
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I set up a hydrogenation reaction. In this transformation, I wanted to reduce a nitrile to the corresponding primary amine. I found a protocol in which the nitrile group was reduced by exposing the substrate to Raney Nickel under an atmosphere of hydrogen.
Disclaimer: All chemical reactions demonstrated in this video are performed by trained professionals in a controlled laboratory environment. Do not attempt to replicate these experiments without appropriate training and supervision. Always use personal protective equipment (PPE) including lab coats, safety goggles, and gloves when handling chemicals. Be aware of the specific hazards associated with each chemical used, such as toxicity, flammability, and reactivity. For detailed information on each chemical refer to Material Safety Data Sheets (MSDS) or Safety Data Sheets (SDS). The creators of this video are not responsible for any harm or injury resulting from the misuse of the information provided. This video is for educational purposes only.

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23 сен 2024

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Комментарии : 8   
@OrganicMechanismsChannel
@OrganicMechanismsChannel Год назад
Very nice lab videos. I am wondering why you are not using a shlenk line for switching between the inert gas and vacuum. Maybe you just don't have one on hand but I find it much better for purging the flask before the hydrogen and you do not have to switch out stoppers as much so the reaction is better sealed.
@mgrzeg
@mgrzeg 4 месяца назад
Obtaining primary amines from nitriles requires ammonia presence (or other organic base), not acetic acid; Additionally raney nickel requires really high pressure, over 30atm, not just baloon.. Did You received anything beside starting material here?
@NROChemistry
@NROChemistry 3 месяца назад
Yes, the product.
@fadiyosef4452
@fadiyosef4452 8 месяцев назад
Hello, How long does the reaction last if we want to hydrogenate benzene into aromatic hexane?? Thank you.
@xpndblhero5170
@xpndblhero5170 Год назад
Even though you was speaking clearly, I didn't understand what you were doing.....
@NROChemistry
@NROChemistry Год назад
Basically, this is a procedure for the reduction of a nitrile to the corresponding amine with hydrogen gas and a Ni catalyst.
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