Immune System, Part 2: Crash Course Anatomy & Physiology #46

Подписаться 16 млн

Просмотров 3,7 млн

50% 1

In the penultimate episode of Crash Course Anatomy & Physiology, Hank explains your adaptive immune system. The adaptive immune system's humoral response guards extracellular terrain against pathogens. Hank also explains B cells, antibodies, and how vaccines work.
Pssst... we made flashcards to help you review the content in this episode! Find them on the free Crash Course App!
Download it here for Apple Devices: apple.co/3d4eyZo
Download it here for Android Devices: bit.ly/2SrDulJ
Chapters:
Introduction: Adaptive Immune Responses 00:00
How B Cells Identify Antigens 2:14
B Cells Become Effector Cells & Memory Cells 4:05
How Antibodies Fight Antigens 5:22
Active and Passive Humoral Immunity 6:03
How Vaccines Work 6:27
Review 8:30
***
Crash Course is on Patreon! You can support us directly by signing up at / crashcourse
Thanks to the following Patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
Mark, Eric Kitchen, Jessica Wode, Jeffrey Thompson, Steve Marshall, Moritz Schmidt, Robert Kunz, Tim Curwick, Jason A Saslow, SR Foxley, Elliot Beter, Jacob Ash, Christian, Jan Schmid, Jirat, Christy Huddleston, Daniel Baulig, Chris Peters, Anna-Ester Volozh, Ian Dundore, Caleb Weeks
--
Want to find Crash Course elsewhere on the internet?
Facebook - / youtubecrashcourse
Twitter - / thecrashcourse
Tumblr - / thecrashcourse
Support Crash Course on Patreon: / crashcourse
CC Kids: / crashcoursekids

Опубликовано:

12 июл 2024

Ссылка:

Скачать:

Готовим ссылку...

Добавить в:

Мой плейлист

Посмотреть позже

Комментарии : 1,1 тыс.

@crashcourse 4 года назад

Pssst... we made flashcards to help you review the content in this episode! Find them on the free Crash Course App! Download it here for Apple Devices: apple.co/3d4eyZo Download it here for Android Devices: bit.ly/2SrDulJ

@thomascatt7696 4 года назад

1 day ago??? Its 2020 and this episode was made in 2015.

@InfinitySwordofDiamond 4 года назад

I agree lol

@drumandball 8 лет назад

Gotta love the moment when your're stressing out for your biology final and then you find yourself snickering because of the facial expression on a macrophage.

@mrblexit7152 5 лет назад

Lol

@gabrielnito6606 5 лет назад

*cough* biosci107 *cough*

@MsNowii 4 года назад

@bryanfeliciano4102 4 года назад

Lol, you probably aced it. I watched this after class and within 20 minutes I was like "IT ALL CLICKS!!!"

@petertilly9401 8 лет назад

I'm really sick right now so I'm watching this somewhat for me, but I'm tryna teach my immune system to work correctly.

@KarascioM 8 лет назад

I don't think it works that way...

@petertilly9401 8 лет назад

+KarascioM Im like 752% sure it does

@Zeekar 8 лет назад

+Peter Tilly Worse comes to worse, at least you know your sickness looks adorable at the microscopic level.

@Soosss 8 лет назад

+xXx Fioletowy i długi banan który przemierza Redtu-, znaczy, RU-vid z Planety Teletubisiów xXx woosh

@Soosss 8 лет назад

Obese Chicken I remember when I was a kid, I didn't want to go to school so I pretended to be sick, then I actually ended up with a fever. Placebo effects are weird

@1awlsusie 7 лет назад

The animations just make everything very clear and bearable to observe the info much easier.

@ChristopherGray00 6 лет назад

Yeah, i love the production quality in these vids

@user-lv3bh5wt7z 5 лет назад

I want to know better but I can not why

@shellz3295 5 лет назад

I'm #667 like♡.....couldn't leave it 666!!!

@arielsproul8811 5 лет назад

2:46 and 2:51 the transition from "finally going to beat the level" to "(inexpressible emotion, you know the one)" was great

@haizi7179 4 года назад

Infographic animations about anything scientific are my porn

@alyssab537 4 года назад

Watching this during COVID-19....interesting things to think about during these times.

@Scotticus25 8 лет назад

Can T-shirts be made featuring the adorable defense cells please.

@stephaniescheiderman7072 5 лет назад

THIS THO!!!!! ^^^^ i want a neutrophil shirt so bad

@2infinityandbeyond88 5 лет назад

plsssssssssss

@darrellsimon4462 5 лет назад

Yessss I would love a neutrophil and macrophage and red blood cel tshirt

@stuart5892 5 лет назад

i call shotgun on the cell at 5:11

@sonoftheway3528 4 года назад

T Cell T Shirts

@sierralobo7163 8 лет назад

Why is everything so darn cute? XD

@Kay-ni5bm 7 лет назад

especially Hank lol

@shenellsmith6849 7 лет назад

ikr😃😊

@denizenmom3905 6 лет назад

Sierra Lobo idk but it’s adorable

@cornpatches3060 6 лет назад

maplestory look it up green jelly and mushroom characters are in it its a mmorpg

@AxelZaore 6 лет назад

probably because sometimes it's way more boring in real life lol

@agglyusr 4 года назад

I'm so glad Hank has a kid. I bet his wife is super cool, too. Everyone at crash course must be pretty damn awesome. Thank you all.

@lukejouflas5589 10 месяцев назад

This man has taught me more about the immune system in ten minutes than my professor at a T20 school could in three lectures.

@petraleong 8 лет назад

now i want a plushie of all the different immune cells... they are so cute!

@redstonebear7_342 4 года назад

Meee too.

@gokulsankar6866 4 года назад

Ikr

@priceaka13 7 лет назад

Studying with animation is the best

@filitaliangirl 7 лет назад

Price Chinedum if I could thumbs-up this 100 times I would

@deanc9453 4 года назад

@BRockandriffs 8 лет назад

Am I the only one that watches these for fun and personal use rather than for a class? Just curious

@Lumamaster 8 лет назад

+BRockandriffs I do as well! Plus the animations are AWESOME!

@erikziak1249 8 лет назад

+BRockandriffs No, you are not the only one.

@darrianweathington1923 8 лет назад

+BRockandriffs im sure most ppl watch for fun, i dont think most classes go this far in A&P anyway, they usually stop right before reproduction

@arousedsquirrel2429 8 лет назад

+BRockandriffs Nope I do it for the exact same reasons. These videos help me understand, well, a lot of stuff;, and enable me to go onto some much more serious websites with a solid amount of knowledge.

@BRockandriffs 8 лет назад

+Aroused Squirrel could you name me some of those "serious websites" you mentioned for my personal reference if that's not too big a favor to ask a stranger.

@SBroproductions 8 лет назад

Bio Exam is tomorrow, was literally waiting for a week. Thanks Hank :)

@rudabuddhagaming3120 8 лет назад

+SBroproductions Are you in my Bio class? o.O hahaha

@SBroproductions 8 лет назад

RudaBuddhaGaming Jill Ranger, Charlie, Ursala? Do those names sound familiar?

@rudabuddhagaming3120 8 лет назад

Yes! Who's your teacher?!

@SBroproductions 8 лет назад

RudaBuddhaGaming Jill Ranger. You?

@lisha9659 8 лет назад

+RudaBuddhaGaming Good luck you two :)

@daedra40 8 лет назад

The animations are so cute and lovely (even though the actual antigens are typically jerks-to-humans), the content so educational, and the fact that this is the penultimate episode is so upsetting. Long live crashcourse!

@1075Rah 8 лет назад

Oh my god, he used a Maplestory animation. I never thought I'd see the day. Gj man.

@pranavsukumaran8154 6 лет назад

I wanted to get into maplestory again. Then I saw the menu hell and the shitty resolution. I don't know how I played that before.

@JayjayCampos 6 лет назад

1075Rah same! I miss MS!

@JayjayCampos 6 лет назад

i logged back in and it wasnt the same. it gave me anxiety just looking for whatever i need. Its not the same. -_-

@elfatimah3755 6 лет назад

hahahah i'm shocked when i saw orange mushroom, and i was like "did he plays maplestory too?'

@JayjayCampos 6 лет назад

El Fatimah lol

@someperson111 8 лет назад

This is easily the best video you've guys and girls have done graphically. I'll never forget memory cells looking like wizards lol

@mandya3105 8 лет назад

MAKE A GAME OF THIS PLEASEEEEEE

@johnnathanalvarado3206 3 года назад

You guys are amazing. I am in nursing school, and this is my distance learning assignment. I don't think learning about anything has been this interesting ever. Love the World of Warcraft and gaming references. Nerds rule! Thank you!

@RNH2O 7 лет назад

Hey future nurses!!!

@artemisstehley4606 7 лет назад

Hello! It's nice to meet you! :-D

@RNH2O 7 лет назад

Jessica Stehley hello!! Nice to meet you 😊happy studies to you!

@matthewwayne98 7 лет назад

Hey, happy studies, from a future rad tech here!

@09Drdray 6 лет назад

Well hello

@livelikeyourdieing15 6 лет назад

Almost a year later lol but hey 😊

@drink15 8 лет назад

Didn't think anyone remembered Maplestory. Any old Gunbound players?

@Lumamaster 8 лет назад

+drink15 I remember my brother playing that game when I was very, very young and didn't know much.

@Enix19MS 8 лет назад

+drink15 Yeah, I played both Maplestory and Gunbound. They were fun in the past.

@Borednesss 8 лет назад

+drink15 Pro boomer

@mdnpascual 8 лет назад

+drink15 nakmachine player reporting

@silver222333 8 лет назад

+drink15 Pro asate here and also quite some years on Maplestory

@haileyquartermain379 8 лет назад

I had no idea what my prof was talking about when they explained this in class. This helped me so much! May actually pass my midterm now!

@coenijn 8 лет назад

It's pretty funny how I, a 3rd year biomed student, learn 1 or 2 things in these episodes that I didn't learn from my immunology prof. Good job Crash Course, good job.

@electromika 8 лет назад

My humoral system only protects my forearm, right? Man I'm humerus today.

@TheScheiss 8 лет назад

Jejejeje

@jamesfidge 8 лет назад

humorus is the upperarm bro

@electromika 8 лет назад

+James Fidge Did you hear that? That was my joke flying over your head.

@TheHanspeter8 8 лет назад

+Sulthan14 I think he got the concept of your joke (the word play between humerus and humorous) but he was merely correcting your error. You should have said "My humoral system only protects my upperarm, right? Man I'm humerus today."

@NijosoSefzaps 8 лет назад

+Sulthan14 What's the joke? Don't you know some people have broken their humerus before?

@skyliner114 8 лет назад

These cells are too cute.

@vdyphuong 4 года назад

Thank you so much for making these amazing videos. I used to watch these when I was taking A&P in undergrad. Now, I rewatch them as a refresher course for Advanced Pathophysiology. Still helpful as ever!

@atomicsassy 8 лет назад

The Maplestory reminiscence T.T Love this!

@iTrustInTheMusic 6 лет назад

@Yesmayo1982 5 лет назад

@bunkieboy3052 4 года назад

"And that's why vaccinations are pretty much the greatest thing ever" Anti-Vaxxers: *surprised Pikachu face*

@theaveragedavid8689 4 года назад

NOPE

@bunkieboy3052 4 года назад

LETS GET 1000 subs They kinda are

@theaveragedavid8689 4 года назад

@@bunkieboy3052 Say what U wanna say but dude honestly in the end I dont wanna be mean

@bunkieboy3052 4 года назад

LETS GET 1000 subs Have fun getting polio

@Dan-cg1te 7 лет назад

Im a simple man, i see Maplestory reference, i like the video.

@gokulsankar6866 4 года назад

lol

@nikolaralchev5811 4 года назад

I passed my physiology exam, thanks to this dude !!!

@robynmcmillan 7 лет назад

Who else wishes there could be some kind of cartoon animation series telling the heroic stories of our bodies' cells battles with germs? These animations are toooooooooooooo cool!!

@41767762 6 лет назад

I am in the library watching this and could not stop smiling :) People around me must think I am procrastinating! Love the animation and how you explain things. Makes learning so much more fun! Thanks heaps.

@RangerSparky73 8 лет назад

AH i love the animation in this, it's always so cute!

@RangerSparky73 8 лет назад

now i want to hug my cells and immune system

@jonathanschossig1276 7 лет назад

Especially the one at 6:22, right?

@GingeredHonii 7 лет назад

that was not cute..

@ElijahFoster8 7 лет назад

2:41 - 2:52 the viruses expression was so funny to me

@WeissLiebe 8 лет назад

Animation was so cute, so accurate and Hank is so charming... LOL I always 'like' these videos before even starting 😙

@WutLawl 7 лет назад

crash course please do some grad level stuff ID LOVE YOU LONG TIME. 😎

@sonoftheway3528 4 года назад

^this

@travisk5589 5 лет назад

I have watched dozens of Crash Course videos for the past year. Everything from chemistry psychology and anatomy and physiology. This three-part series on immunity is by far the best. Hysterical and easy to understand thanks for you guys it's time for making memes.

@t0natiuh454 6 лет назад

Hello! Right now Im studying for Pharmacological Chemistry and for my 16 years old sometimes i really struggle while trying to remember things but this channel is so amazing!! the animations make everything so easily going that i just enjoy watching all your videos, definitely i will recommend this channel to my classmates!.

@maffieumufasa3155 5 лет назад

These animations are so good and helpful.

@metushelach8 5 лет назад

4:32 Actually not entirely accurate. Activation by T-independent antigens is weaker and does not result (usually) in immunologic memory (in contrast to T-dependent antigens which gives a stronger response, resulting in the development of immunologic memory). But I guess they wanted to keep it simple.

@Aphelia. 4 года назад

Yeah I wanted to hear more about T-cells

@jeanlanz2344 4 года назад

This and the other Immune System videos are some of the best in the whole A & P series. Great explanations and animations to describe adaptive immune responses to specific germs on a systemic level. Thank you!

@NjniaVanDerWald 8 лет назад

animator is on a roll! Keep taking what you're already taking. Seems like a reasonable drug!

@hendrikswart4814 7 лет назад

Wow, you make it so easy to understand this complex system. Thank you for saving my grades.

@faifai4 8 лет назад

Hank, you make this educational vid so fun for kids to watch. =D

@romero1337 8 лет назад

This is the best channel on youtube, great work crash course keep it coming!

@ersantosjr 7 лет назад

thank you guys for this. Thank God for this youtube channel. this has helped me tremendously prepare for my advanced pathophysiology class! you guys make dense information sound so fun!

@romjr1602 8 лет назад

Hi guys from CrashCourse! I'm willing to donate some of my time for you. I can translate videos to Portuguese! Just pick one!

@mistersquirtlegamingandtut5936 7 лет назад

I'll try to get them to notice

@mistersquirtlegamingandtut5936 7 лет назад

Try sending them an email

@aftermach5542 4 года назад

Cells: I remember *EVERYTHING* Me: I can’t remember for my anatomy test :(

@iartistdotme 8 лет назад

Excellent series! I wish you had a slow motion button so I could slowly absorb all you are saying. I guess just replay over and over works and appreciate this info SO much!

@user_25815youtube 7 лет назад

You are incredibly awesome. Your videos got me through graduate anatomy and phys 1 and now i'm in part 2! the little cell faces are SO cute and everything you do to put these together are wonderful and soooo beneficial!!

@TheDeekins 8 лет назад

Gonna miss this series, I learned a lot. Thanks so much for all you do Crash Course. Also scrolled down looking for anti-vaxxers, I'll admit it

@sharwinharkal9933 7 лет назад

Can't thank you guys .... appreciated n please don't Stop doing this job.... an awesome job ...... thank you

@carmenpuisis1082 5 лет назад

Crash Course should make movie of fighting germs in our bodies. It would be very interesting and knowledge that everyone need to know about our body fighting system.

@danieldonovan4063 7 лет назад

Wow ... this is the best system Crash Course has covered. VERY easy to comprehend considering how complex the immune system can be. I just emailed this to my anatomy professor. Well done, please keep these kind of videos coming!!

@BenG9C9 8 лет назад

This is a great series!

@aang7505 8 лет назад

I love how they sneak in Pokemon in their episodes!

@matthewperez07 8 лет назад

Man I love these series! I learn so much from these videos, thanks Crash Course for the amazing teaching!

@adellewoodcock2944 7 лет назад

I have to say, i have been struggling with this for 2 days, this video made so much sense. Thank you so much!

@TheCaptain14 8 лет назад

4:17 HYPER BEAM! (Pokemon Red/Blue & Gold/Silver)

@carlitosvodka 8 лет назад

I REALLY LOVE HOW THIS IS EXPLAINED. SCIENCE IS FUN! KEEP DOING GREAT STUFF. DFTBA!

@jpeg212 5 лет назад

I'd like to start by saying that I absolutely love this channel but.... According to the Fundamentals of A&P 10th Edition (Martini/Nath/Bartholomew) book chapter 22 -"The B cell differentiates into plasma cells and antibodies/immunoglobulins." - also it reads that the T cells are the ones that differentiate into Memory cells, not B cells.

@Bayezhaze 5 лет назад

jpeg212 that is wrong. The plasma cell creates the antibodies, not the B cell. When a B cell divides it creates 2 daughter cells. It divides into a plasma cell that creates antibodies and a memory cell called a B memory cell. There are both T memory and B memory cells. Have you taken microbiology ? It teaches you all of this.

@LowScoville 8 лет назад

omg, a three part series on the immune system?! my immuno final was yesterday lol Immunology was probably one of the toughest classes I've had to take, along with biochem and cell bio (immunology was the most difficult). I loved the class but hated getting tested on it, just because there are a lot of mechanisms not shown in the video. EITHER WAY yayyy I'm so glad people get to be primed with this video from here on out. This was long over due :D

@MultiMaikimaik 8 лет назад

Maplestory? xD Awesome! I didn't know anyone remembered that game :D

@Kingwut117 8 лет назад

NO I CANT WAIT :( This is so cool

@lisafink1024 4 года назад

I love this series, one of the best! Great story to illustrate immune system, thank you

@patrickperico589 7 лет назад

Never thought I'd be sooo overwhelmingly amazed and intrigued by this topic!

@brianfebles3113 Год назад

if you guys make an actual video game like that i will play for sureeee, thank you for these awesome videos.

@AHo-ne2df 8 лет назад

So excited for last episode!!!!

@jeranichols2002 8 лет назад

Same here! Going to miss these so much!

@purecargirl 8 лет назад

You have no idea how grateful I am for your videos! Thank you!!

@paulapinto5907 5 лет назад

amo que existan videos como este, tan fáciles de comprender y al mismo tiempo de recordar

@liekes9344 8 лет назад

Lol maple story! That was a game I played a lot once upon a time 😝

@Zsil33 8 лет назад

Those bacteria that got captured by antibodies were so done with the immune system...its like they were saying "Seriously? Again?"

@auggirangel8829 6 лет назад

This is the best way to teach honestly, I was engaged through the whole thing... I leveled up!

@basspulse101 8 лет назад

The animation and explanations for this video is the best ever. Perfect analogies and clear animations well done crash course :)))

@zacharylai6933 5 лет назад

The animation is so cute that i kinda feel bad when the flu virus gets binded to the b cell and frowned :(

@jenniferdoss622 4 года назад

Thank you! These videos are making it possible for me to pass (specifically write essays) for Microbiology, and Anatomy & Physiology 1 & 2

@amalbousere3470 6 лет назад

my exam is tomorrow and these videos came extremely helpful i'm really in love with this channel everything is well made the animation is fun it keeps me entertained it would had been better if you had mentionned cytokines but it's not a big deal, please guys keep up the good work

@Comp144Gaming 8 лет назад

I love how you put in positive and negative selection when describing the maturation process. Subtle and perfectly accurate :D

@disappointmentjuice8676 4 года назад

0:02 is that a neutrophil cosplaying as link im losing it-

@LolixBelle 5 лет назад

watching cells at work while playing maplestory m...didn't expect the animation to do a tribute to maple ....XD

@humanatee6639 5 лет назад

I love cells at work

@jokernu1fan 8 лет назад

This episode is great. The MMO comparison is really helpful for remembering, and I'm not even studying any more. This stuff is just interesting.

@Jtbg80 5 лет назад

Love this channel. Being a visual, these videos really help.

@ibraheemalshaer 8 лет назад

can you please make an episode about vaccines, their advantages and disadvantages .. and give a general idea about the myths like "vaccines cause autism" and so ..!! :D

@enfantterrible456 8 лет назад

Not a "myth" anymore. On August 27, 2015 dr. William Thompson who is a senior scientist and epidemiologist at the CDC through a whistleblower attorney released documents stating that the cdc lied about the connection between the MMR vaccine and autism in their 2004 article in the Journal Pediatrics. Check it out!

@joelvr101 8 лет назад

+Enfant Terrible That really, really small chance of getting autism with vaccines against that really big chance of getting polio without them. I think ill choose for the option that won''t kill me.

@ibraheemalshaer 8 лет назад

Joël Van Rijn exactly!!! thankyou! :D

@alexschrijnemaekers8067 8 лет назад

+Enfant Terrible Cool. But I prefer my sources over yours. scienceblogs.com/insolence/2015/08/05/the-cdc-whistleblower-william-thompson-appears-to-have-gone-full-antivaccine/

@mohamedalmajed2428 8 лет назад

+Enfant Terrible Wait. I can't believe that there actually *are* people who still think that Vaccines cause Autism. How shallow must you be.

@StoneCresent 8 лет назад

Hank, where is the video on the mammary glands? I thought that they would be covered as part of the reproductive system videos but they are barely mentioned. Why is a defining feature of mammals largely absent from a course on human anatomy and physiology? I can think of reasons but I would prefer to hear your explanation on the matter.

@CodexCat 8 лет назад

Nooo! I need the video about cell-mediated immunity now! My final is tomorrow :'( On the flip side, AMAZING videos. It's always so easy to understand, and I love the animations. Keep up the great work!

@ParkerSolemSevier 8 лет назад

This video just answered a question that has been bugging me for years. This has been the most anticipated CrashCourse episode for me for that reason.

@lateasecoddington-wardell3100 8 лет назад

THANKS FOR HELPING UNDERSTAND WHATS GOING ON IN MY DAUGHTERS SWOLLEN LYMPH NODES

@masol3726 7 лет назад

So cool. Like ur cells fighting ebola and dont know how to defeat it so they are trying to destroy it. Then a cell that survived ebola, tells them the hacks and how to beat ebola.

@crazyfreak9188 8 лет назад

I love learning, and I love these videos! This is more entertaining than some sitcom.

@CezrDaPleazr 8 лет назад

Thank you so much for all of these videos you guys make at Crash Course, you guys teach so much!

@denisskenderovic3707 5 лет назад

I cracked up when the flu virus got stuck to the lymphocyte .

@jackmack1061 6 лет назад

Gentlemen, take particular note... Just a warning that mumps immunity can be lost. I am a medical student nearly 50 years old and as part of preparation for placements in the clinical setting we need to be fully immunised... blood test revealed have lost my mumps immunity since having mumps as a child.

@victoriabreu5782 6 лет назад

I love crash course so much. You have taught me to love science and the way you present it is just fantastic.

@ilonalaverty 7 лет назад

I swear these videos helped maintain my A in A&P!!! Thank you!!!

@theaveragedavid8689 4 года назад

I am just saying to every one who disagrees tell me your theory because i know this stuff also my mom was a nerse

@aryankadam3714 8 лет назад

Pls make crashcourse physics

@Lumamaster 8 лет назад

+Aryan Kadam yes pls

@JM-lh8rl 8 лет назад

It's out!

@timstring0902 8 лет назад

This Immune System Crash Course series is the best crash course I ever had :)

@Tepid24 8 лет назад

Very much looking forward to the next one. This is good stuff.

@ethanrecords3612 4 года назад

Pathogen🦠:I love wondering around here

@ethanrecords3612 4 года назад

BCell: GOT IT😈

@ethanrecords3612 4 года назад

Pathogen:NOOOOOO

@aperson22222 8 лет назад

I still think reproduction would be a more logical stopping point, but cell-to-cell combat does sound like it should make for an exciting finale. I've really enjoyed this course, sad to see it go, but looking forward to the next one, whatever it is.