Immunology Lecture 16 - Type IV Hypersensitivity Reactions

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This lecture covers T cell-mediated delayed hypersensitivity reaction (Type IV). Sensitized T cells release cytokines that activate macrophages and act as chemotactic agents for inflammatory cells. Issues like Type I Diabetes Mellitus, Multiple Sclerosis, Guillain Barre Syndrome, Hashimoto's thyroiditis, Graft vs host, contact dermatitis and PPD are talked about. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

Опубликовано:

8 ноя 2013

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Комментарии : 84

@DrBeenMedicalLectures 9 лет назад

Immunology Video: Hypersensitivity Type IV ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-TJM-lBc9rWU.html

@eddiedann6472 3 года назад

Fantastic!!!! Thank u n God Bless u n ur loved ones. 👏👏👏

@MrNima1997 6 лет назад

This is the best video regarding type 4 hypersensitivity! Thank you!

@lindanguyen6108 8 лет назад

You sir, are an excellent educator.

@subhashchandrajangir3749 8 лет назад

most clear concept.. make very nice......thanks sir

@hothpalpanom4410 5 лет назад

thank you dr and i hope my presentation on type four will go better you really sacrifice.you are hero

@abbassyednhs 9 лет назад

Amazing Dr Mobeen

@hotshitattitude 3 года назад

Dr. Syed, thank you for the helpful video! Just an aside, your handwriting is beautiful.

@hafsamushtaq7677 3 года назад

Mind blowing..It is Very helpfull lecture

@siddhidesai6532 9 лет назад

Thank you. Helpful and quite in deapth.

@ozz530 10 лет назад

Thank you and God Bless

@sejal6329 5 лет назад

thankyou so much. god bless you!!

@Salma-baeisa 4 года назад

You are just amazing thank you so much god bless you

@adityadhand476 7 лет назад

Marvellous job sir ! Respect

@DrBeenMedicalLectures 7 лет назад

Thank you. Find more lectures on drbeen.com.

@safiullahrahmani5492 7 лет назад

Thank you Sir...it was super

@dnabiology6659 6 лет назад

Very nice teaching sir thanku very much keep it up god work for students

@Elly3121 9 лет назад

Thank you Dr. Mobeen

@DrBeenMedicalLectures 9 лет назад

You are welcome!

@DrBeenMedicalLectures 9 лет назад

Bokan sb: you are correct MS affects white matter of the CNS. These are Oligodendrocytes.

@vivekdadhania 9 лет назад

Awesome! Thank you.

@DrBeenMedicalLectures 9 лет назад

You are welcome!

@anjidodiya4675 6 лет назад

Superb sir nice explaination

@saynabmohamud6891 6 лет назад

Thanks drbeen, very good explanation

@DrBeenMedicalLectures 6 лет назад

Pleasure. Check drbeen.com for more lectures.

@reemalotaibi6506 6 лет назад

thanks a lot ... it was helpfull

@tulasazenith951 3 года назад

Thank you sir🥰🥰😊

@DrBeenMedicalLectures 10 лет назад

vwziful - could not reply to your post. Something with this new commenting system prevents me from replying to your post. Hope you can read this comment: I am talking about the blistering due to contact with chemical substances or plants.

@sabamalik1004 6 лет назад

Thanku much Sir for hypersensitivity lectures.. these helped alot .. thanku once again

@DrBeenMedicalLectures 6 лет назад

My pleasure. Check out drbeen.com for more lectures.

@adityamalladi1157 9 лет назад

very clear. thank u so much.

@DrBeenMedicalLectures 9 лет назад

aditya malladi you are welcome!

@enadmohamed5433 9 лет назад

thank you so much . you are really great doctor

@DrBeenMedicalLectures 9 лет назад

Thank you!

@sanaayunus4209 7 лет назад

seriously u teach in the best way..😊 thanks alote for the video

@DrBeenMedicalLectures 7 лет назад

Good to know. There are more lectures to keep you happy. Visit: www.drbeen.com/catalog

@DrBeenMedicalLectures 7 лет назад

Glad that you like our teaching. Please find more videos on www.drbeen.com/catalog Best Mobeen

@awaismehmood690 5 лет назад

Very very informative and knowledgeable

@DrBeenMedicalLectures 5 лет назад

Thank you!

@ahmadadam1044 7 лет назад

Thank you very much u are indeed great

@DrBeenMedicalLectures 7 лет назад

You are most welcome. Study well and continue being the best! Check drbeen.com for more lectures.

@tanimasasmal4081 3 года назад

Sir, please make a complete details video on 'polyclonal and monoclonal antibody "for exam. All this video on ' hypersensitivity reaction' helps me a lot. Thanks to you for this.

@venkybly 3 года назад

@MedManiac1 7 лет назад

superb

@DrBeenMedicalLectures 7 лет назад

Thanks

@Scully69 10 лет назад

very very well structured! i really enjoyed it! have you ever considered doing more pathophys / pharma? ;)

@manjarichaudhary5400 6 лет назад

I really gone fan of u sir

@DrBeenMedicalLectures 6 лет назад

Thank you, dear. Study well.

@saishannu 6 лет назад

Sir, Please upload a lecture on coagulation cascade and coagulation tests integrated within. Thank you Sir. Expecting a positive response.

@atifjan70 7 лет назад

Very interesting teaching thank you so much, have u made any video on Serology tests?

@DrBeenMedicalLectures 7 лет назад

Not yet.

@EvasiveEvo 7 лет назад

guillean barre is a type 2 hypersensitivity due to antigenic similiaruty to camplobacter.

@22inominata 8 лет назад

MS = demyelination of oligodendrocytes GBS = demyelination of schwann cells

@ramshaijaz5169 5 лет назад

Will you plz upload type 2 hyper sensitivity?

@beautyamy2487 8 лет назад

Thank you very much doctor mobeen ., please is there a video about hypersensitivite type 1 and 2 !!!?

@DrBeenMedicalLectures 8 лет назад

+imane amy yes. Check in the videos or visit drbeen.com and go to immunology module (it is free). There you will find all videos in a list.

@megwilson9627 9 лет назад

hi, was just wondering if B cells would be involved in any aspect of this immune reaction? I understand that antibodies are not produced but do the B cells act in any other ways?

@pd1296 9 лет назад

In Type 1 DM and MS, can i say that the lymphoctes are sensitised in the first exposure to the islet of langerhans or schwanna cells. then they become memory lymphocytes and they just attack these cells again? So does this mean that memory lymphocytes can straight bind to the antigen and does not need any help from APC?

@dG_Danga 6 лет назад

Sir ,,,make a video about type2 hypersensitivity pls

@md.mahamudunnobimahmud7774 9 лет назад

Sir,which one is for T Cell-mediated Cellular Immunity?

@aakashsharma7340 8 лет назад

thank u so much sir...can u plz upload hypersensitivity 2 lecture as well :)

@DrBeenMedicalLectures 8 лет назад

+aakash sharma will do!

@jordylarco3744 8 лет назад

Where do you find the informations? in which book can i find it ??

@dr.niteshpandey3096 4 года назад

Is der any specific pathogen for multiple sclerosis? like for tuberculosis myobacterium wich goes into the body n causes this reaction

@Tommytorque69 4 года назад

My father has a pet Parakeet that he is now living with for 4 years. Recently this year he was diagnosed with pulmonary fibrosis. So are you saying that the Parakeet is the culprit and that he should get rid of the poor little bird? Thank you.

@amys9058 8 лет назад

same with candida test ri8

@dr.niteshpandey3096 4 года назад

warthins tumour is also a type 4 reaction

@vwziful 10 лет назад

but blistering in pemphigoid vulgaris and bullous phemphigus is type 2??

@vfrc152 9 лет назад

Thank you, the lecture was laid out in a very organized manner and was very inclusive. The camera man could take a little less artistic license.

@DrBeenMedicalLectures 9 лет назад

Thank you for your comments Eric Watkins. I enjoyed the camera man's license thought from you :-)

@Solo.Gr8 8 лет назад

hello dr saab..i have a query in delayed hyper sensitivity reaction when cd4 is activated by antigen presenting cells (like in case of tuberculin test) they became sensitive and wait for the antigen to re enter the body. why they don't follow the tradianal path like garbbing the tuberculin molecule presenting the antigen to b cells and provoke a humoral response instead of cell mediated and damaging the tissue by casies necros? and thank you for your contributions

@DrBeenMedicalLectures 8 лет назад

+Sulaiman Gran it is not that the cells will only work through one pathway. It is the predominance of the result. All mechanisms that can engage in a given situation do become engaged. Some are more effective than others.

@Guiltfreedelight 6 лет назад

sir, type 1 diabetes is disease which is due to type 4 hypersensitivity section- intracellular pathogenic antigen where macrophage activates T1cell which in turn activates macrophage by IL12 and IFN gamma cycle and cause damage to tissue. ok but what is the pathogen here?

@DrBeenMedicalLectures 6 лет назад

No pathogen is involved for type 1 DM.

@lekshmi_sankar 4 года назад

which type of auto immune disease does crohn's disease come under?

@bibekbastakoti5290 4 года назад

Dr what about costimulus for Cytotoxic T cell activation in Contact Dermatitis? Can killer T cell function properly without co-stimulus Il-2 ???

@HimanshuKumar-dv6nb 4 года назад

Co stimuli is not needed for killing function, it is only required to activate CD8+ T cell

@HimanshuKumar-dv6nb 4 года назад

He is actually talking about memory cytotoxic t cell in skin formed after primary exposure the work in kind of same way as memory B cells they also don't need costimulation for activation